Abstract:
A method and device for enhancing the power correction of optical measurements in an optical measurement arrangement, the steps including: providing a light source for producing a light beam; splitting the light beam into two beams; directing a first split light beam through an interrogation area and into an optics separation device; directing the light beams from the optics separation device and a second split light beam representing the intensity of the illumination of the main light beam of the light source into cells of a detector array; measuring and assessing the information obtained in the cells; and using this information to calculate the corrected value for the cells receiving the light beams from the optics separation device in order to adjust the power for the intensity of the light beam of the light source and/or to correct the intensity of the light beams from the interrogation area.
Abstract:
The automatic analyzer comprises a revolving support (5) carrying vessels (6) in which an amount of samples and an amount of reagent are mixed in desired proportions. The support (5) delivers each vessel (6) to an analyzer consisting of several modules (9A) for optical interaction therewith. Each module includes, on one side of the vessels' (6) path, a light-emitting termination (13) while on the other side, in the axis of the beam emitted by said termination (13), are located an interference filter (11) and a photodetector (12). Each module (9A) has its own differential filter (11) and the vessels (6) pass through one at a time, whereby as many different measurements as there are modules are obtained. Furthermore, the vessels (6) are spaced apart so that each module (9A) can make its reference measurement when the light beam crosses the gap between two vessels.
Abstract:
Techniques are described for the detection of multiple target species in real-time PCR (polymerase chain reaction). For example, a system comprises a data acquisition device and a detection device coupled to the data acquisition device. The detection device includes a rotating disk having a plurality of process chambers having a plurality of species that emit fluorescent light at different wavelengths. The device further includes a plurality of removable optical modules that are optically configured to excite the species and capture fluorescent light emitted by the species at different wavelengths. A fiber optic bundle coupled to the plurality of removable optical modules conveys the fluorescent light from the optical modules to a single detector. In addition, the device may control the flow of fluid in the disk by locating and selectively opening valves separating chambers by heating the valves with a laser.
Abstract:
A fluorescence measuring apparatus is arranged to measure, substantially at the same time, a plurality of samples in a sample chamber or a plurality of points of the same sample, with the use of an excitation light source. The fluorescence measuring apparatus has a rotary sample stand (2) at the excitation light irradiation position, a plurality of through-holes (2a) are formed in the circumference of the rotary sample stand (2), and a sample placing unit (3) is insertable in each of the through-holes (2a). By moving the sample stand (2) relatively to the excitation light irradiation position, fluorescence measurement can be made on a plurality of samples without sample replacement required in a sample chamber (1).
Abstract:
A reaction segment (1) for a colorimetric analyzer is removably mounted on a revolving plate of the analyzer so that the reaction vessels (3) of said segment (1) are brought one after the other into contact with a measuring device of the analyzer. Said segment (1) consists of transparent vertical reaction vessels (3) which are rigidly fixed to a horizontal bar (4) having connected thereto a horizontal plate (5) to which is fixed a device (6) for positioning and guiding into loading and unloading devices of the analyzer and into the opening of the revolving plate. The loading device and the unloading device are also described.