-
公开(公告)号：EP0773030B1
公开(公告)日：2003-09-03
申请号：EP95921113.7
申请日：1995-06-07
CPC分类号： C07K14/285 , A61K39/00 , C07K14/235
摘要： The invention aims at providing a process for preparing a necrotoxin, an improved toxoid of a necrotoxin produced by a bordetella, and a toxoid mixture comprising the improved toxoid and a toxoid of a necrotoxin produced by a pasteurella. The invention provides a method of partially purifying a necrotoxin by bringing a necrotoxin-containing solution into contact with either a chromatographic carrier gel sulfated by direct sulfation or a chromatographic carrier gel covalently bonded to a sulfated molecule to thereby make the necrotoxin adsorbed on the gel, followed by the elution thereof from the gel. Also provided are a toxoid derived from the necrotoxin produced by a bordetella and partially purified by the above purification method and a toxoid mixture which comprises the above toxoid and a toxoid derived from a necrotoxin produced by a toxigenic pasteurella and is safe for swine and efficacious in preventing atrophic rhinitis.
-
32.发明公开CELL USABLE IN SERUM-FREE CULTURE AND SUSPENSION CULTURE AND PROCESS FOR PRODUCING VIRUS FOR VACCINE BY USING THE CELL 有权在病毒生产无血清培养合适的细胞培养物悬浮液和方法作为疫苗使用细胞
公开(公告)号：EP1260581A1
公开(公告)日：2002-11-27
申请号：EP01908228.8
申请日：2001-03-02
IPC分类号： C12N5/06 , C12N7/00 , C07K14/005 , A61K39/12
CPC分类号： C12N5/0686 , A61K39/12 , C12N7/00 , C12N2500/92 , C12N2510/02 , C12N2710/16634 , C12N2760/16134 , C12N2760/16234 , C12N2760/18434 , C12N2760/18734 , C12N2770/36234
摘要： A novel MDCK-derived cell line (B-702) is provided that can be grown in the absence of fetal calf serum and in suspension culture for allowing a tank culture on the production scale and needs no carrier in suspension culture, as well as a process for producing virus for vaccine by using said cell line in a low-cost, highly safe and stable manner.
摘要翻译： 本发明提供一种新颖的MDCK衍生细胞系（B-702）也可以在不存在胎牛血清和在悬浮培养物中生长，以允许在生产规模的罐培养，无需载体在悬浮培养中，以及一个 用于通过使用所述细胞系在一个低成本，高安全性和稳定的方式制备用于疫苗病毒的过程。
-
33.发明公开
公开(公告)号：EP0914830A4
公开(公告)日：2002-03-20
申请号：EP97907445
申请日：1997-03-24
申请人： JURIDICAL FOUNDATION
发明人： HAMURO TSUTORNU , NAKAHARA YO , TAKEMOTO SUMIYO , MIYAMOTO SEIJI
CPC分类号： A61K38/57 , Y10S514/885 , Y10S514/886 , Y10S514/914
摘要： An inhibitor for neovascularization caused by the proliferation of vascular endothelial cells characterized by containing a tissue factor pathway inhibitor (TFPI) as the active ingredient. The TFPI-containing inhibitor can effectively inhibit the neovascularization, so that it is useful as a preventive or remedy for pathological conditions accompanying neovascularization, such as malignant tumor.
-
34.发明公开POLYCRYSTALLINE THIN FILM AND METHOD FOR PREPARATION THEREOF, AND SUPERCONDUCTING OXIDE AND METHOD FOR PREPARATION THEREOF 有权多晶薄膜AND METHOD FOR ITS和超导氧化物和方法及其
公开(公告)号：EP1178129A1
公开(公告)日：2002-02-06
申请号：EP00978005.7
申请日：2000-11-29
发明人： IIJIMA, Yasuhiro, Fujikura Ltd. , KIMURA, Mariko, Fujikura Ltd. , SAITO, Takashi, Fujikura Ltd., 5-1, Kiba 1-chome
CPC分类号： H01L39/2461 , C01G25/00 , C01G27/00 , C23C14/08 , C23C14/3414 , C23C18/1216 , C23C18/14 , C30B23/002 , C30B29/22 , Y10S428/93 , Y10S505/731
摘要： The polycrystalline thin film (B) is made of a composite oxide of a cubic crystal system which has a pyrochlore type crystalline structure of a composition represented as either AZrO or AHfO (A in the formula represents a rare earth element selected from among Y, Yb, Tm, Er, Ho, Dy, Eu, Gd, Sm, Nd, Pr, Ce and La) formed on the film forming surface of the polycrystalline substrate (A), wherein the grain boundary misalignment angle (K) between the same crystal axes of different crystal grains in the polycrystalline thin film (B) along a plane parallel to the film forming surface of the polycrystalline substrate (A) are controlled within 30°.
摘要翻译： 该多晶薄膜（B）是由选自Y，镱中选择的立方晶系其中有代表作为要么Azro或AHfO（A式darstellt稀土元素中的组合物的烧绿石型结晶结构的复合氧化物的 ，TM，铒，何，镝，铕，钆，钐，钕，镨，Ce和La）的所形成的多晶基体（A）的膜形成表面上，worin相同的晶体之间的晶粒边界的未对准角度（K） 沿着平行于多晶基板（A）的膜形成表面的平面中的多晶薄膜（B）不同的晶粒的轴30 DEG内控制。
-
公开(公告)号：EP1097721A3
公开(公告)日：2001-05-23
申请号：EP00123909.4
申请日：2000-11-03
IPC分类号： A61K9/113
CPC分类号： A61K9/113
摘要： The present invention provides a W/O/W type oil adjuvant vaccine containing an outer aqueous phase containing 0.5 wt% - 20 wt% of a polyethylene glycol derivative having a molecular weight of 400 - 20,000, and an inner aqueous phase containing a biologically acceptable and effective amount of an antigen. The constitution of the present invention that a polyethylene glycol derivative having a specific molecular weight is contained in the outer aqueous phase enables preparation of a W/O/W type oil adjuvant vaccine showing a high adjuvant effect, reduced side effects such as topical response, superior preparation stability and superior workability to allow a person to give an injection easily due to the lowered viscosity.
-
36.发明授权ANTI-FELINE HERPESVIRUS-1 RECOMBINANT ANTIBODY AND GENE FRAGMENT CODING FOR SAID ANTIBODY 失效重组抗体针对猫疱疹病毒-1和基因片段编码它们
公开(公告)号：EP0671472B1
公开(公告)日：2001-03-14
申请号：EP94901002.9
申请日：1993-11-25
CPC分类号： C07K16/085 , A61K38/00 , C07K2317/24 , C07K2319/00 , Y10S424/80 , Y10S424/801 , Y10S424/809
摘要： An anti-feline herpesvirus-1 recombinant antibody which is efficacious in treating, preventing and diagnosing feline herpesvirus-1 (FHV-1) infection, and a gene fragment useful for the preparation of the antibody. A gene fragment coding for the antibody V region bearing an FHV-1 specific avidity of a mouse monoclonal antibody having an excellent activity of neutralizing FHV-1 is obtained by constructing cells which produce the antibody. A chimeric anti-FHV-1 recombinant antibody is prepared from the above gene fragment and another gene fragment coding for a feline antibody C region.
-
37.发明公开IN OVO VACCINATION OF 1 TYPE MAREK'S DISEASE VIRUS 有权在OVO IMMUNISIERUNG GEGEN DAS TYP 1 MAREK'S KRANKHEITSVIRUS
公开(公告)号：EP1064947A1
公开(公告)日：2001-01-03
申请号：EP99959691.9
申请日：1999-12-08
IPC分类号： A61K39/002 , A61K39/02 , A61K39/12 , A61K39/145 , A61K39/15 , A61K39/17 , A61K39/21 , A61K39/215 , A61K39/235 , A61K39/255 , A61K39/295 , A61P31/04 , A61P31/12 , A61P31/14 , A61P31/16 , A61P31/20 , A61P31/22 , A61P33/00 , A61P37/04
CPC分类号： A61K39/255 , A61K39/12 , A61K2039/5254 , A61K2039/5256 , A61K2039/54 , A61K2039/552 , C12N2710/16334 , C12N2710/16343 , C12N2760/18134
摘要： The preset invention provides a method for immunizing chickens which comprises inoculating into growing egg a composition comprising either cell-free attenuated viruses of Marek's disease type 1 or cells infected with attenuated viruses of Marek's disease type 1 capable of producing cell-free viruses. The present invention also provides a method for immunizing chickens which comprises inoculating into growing egg a mixed vaccine comprising said composition plus another vaccine from at least one microorganisms selected from the group consisting of viruses other than virus of Marek's disease type 1, bacteria and protozoan.
摘要翻译： 本发明提供了一种免疫鸡的方法，其包括将包含无细胞减毒的1型马立克氏病毒或能够产生无细胞病毒的1型马立克氏病毒的细胞感染的细胞接种在生长的卵中。 本发明还提供了一种免疫鸡的方法，其包括将包含所述组合物的混合疫苗和来自至少一种选自除了马立克氏病1型病毒以外的病毒的细菌和细菌和原生动物的至少一种微生物接种到生长的鸡蛋中。
-
公开(公告)号：EP0671471B1
公开(公告)日：1999-04-07
申请号：EP94901001.1
申请日：1993-11-25
CPC分类号： C12N15/85 , C07K16/00 , C12N2840/20 , C12N2840/44
摘要： A process for efficiently producing a foreign protein, in particular, a novel foreign protein suitable for the expression of a recombinant antibody with eucaryotic cells by the genetic recombination techniques, wherein a cell containing a foreign gene introduced thereinto can be cultured in a serum-free medium by using as a host cell for foreign gene expression a fused cell obtained by the fusion of mouse myeloma with a lymphoid cell and culturable in a serum-free medium.
-
公开(公告)号：EP0634140B1
公开(公告)日：1999-03-17
申请号：EP94911768.3
申请日：1993-09-24
CPC分类号： A61B17/00491 , A61B2017/00495 , A61L26/0061
摘要： An applicator for spraying tissue adhesive onto an affected portion comprises: a sterilized gas supply chamber; a sterilized gas supply pipe connected to the sterilized gas supply chamber; two sterilized gas injection nozzles for injecting the sterilized gas supplied to the sterilized gas supply chamber in the substantially same direction; two barrel connecting ports, to which forward end nozzles of the barrels are connected; and a spray head having two liquid pipes whose base end portions are connected to the barrel connecting ports and which pass through the sterilized gas supply chamber and project at the forward end portions thereof from the injection nozzles. In this applicator, coating solutions supplied from syringes of the two barrel connecting ports are injected from the forward end portions of the liquid pipes, the sterilized gases are injected from the two gas nozzles in the substantially same direction, and the two types of liquid injected from the liquid pipes are atomized and applied onto the affected portion in a mixed state.
-
40.发明公开
公开(公告)号：EP0823476A2
公开(公告)日：1998-02-11
申请号：EP97113588.4
申请日：1997-08-06
IPC分类号： C12N9/74
CPC分类号： C12N9/6429 , C12Y304/21005
摘要： A method for activating prothrombin to thrombin which comprises treating an aqueous solution containing prothrombin with polyethylene glycol in the presence or absence of the calcium salt. The method of the invention enables conversion of prothrombin to thrombin in the absence of thromboplastin and allows for preparation of thrombin on industrially large scale from easily available starting materials.
摘要翻译： 一种激活凝血酶原至凝血酶的方法，包括在存在或不存在钙盐的情况下用聚乙二醇处理含有凝血酶原的水溶液。 本发明的方法能够在不存在凝血激酶的情况下将凝血酶原转化为凝血酶，并且允许从容易获得的起始原料在工业上大规模制备凝血酶。
-
-
-
-
-
-
-
-
-
搜索结果
425 条记录 (耗时 0.022 秒)
