公开(公告)号：EP0274856A1

公开(公告)日：1988-07-20

申请号：EP87310689.2

申请日：1987-12-04

申请人： THE UNIVERSITY OF KENT AT CANTERBURY

发明人： Knowles, Christopher John ,  Wyatt, Jeremy Michael

IPC分类号： A62D3/00 ,  C12N1/36 ,  C02F3/12

CPC分类号： C12N1/36 ,  A62D3/02 ,  A62D2101/26 ,  C02F3/1231 ,  Y02W10/15

摘要： A process for the microbial degradation of waste characterised in that it comprises determining the significant constituent(s) of a waste, providing one or more microorganisms able at least partially to degrade and/or biotransform and/or mineralise each determined constituent of the waste, optionally providing one or more other microorganisms capable of furthering mineralisation of biotransformation or partial degradation product(s), growing one or more mixed cultures of at least some of the microorganisms on a synthetic mixture of at least some of the determined constituents of the waste and utilising the adapted population of microorganisms substantially to mineralise the actual waste is disclosed.
The present process is generally applicable, but a particular area of use is in the treatment of waste from acrylonitrile production.

摘要翻译： 一种用于废物微生物降解的方法，其特征在于，其包括测定废物的重要成分，提供一种或多种能够至少部分地降解和/或生物转化和/或矿化每个确定的废物成分的微生物， 任选提供一种或多种能够进一步使生物转化或部分降解产物矿化的其它微生物，将至少一些微生物的一种或多种混合培养物生长在至少一些所确定的废物组分的合成混合物上，以及 公开了利用适应的微生物群体实质上矿化实际废物。 本方法通常适用，但是特定的使用领域是用于处理来自丙烯腈生产的废物。

公开(公告)号：EP0047662B1

公开(公告)日：1987-12-09

申请号：EP81304084.7

申请日：1981-09-07

申请人： NATIONAL RESEARCH DEVELOPMENT CORPORATION

发明人： Shirley, Martin William

IPC分类号： C12N1/36 ,  C12N1/10 ,  A61K39/012 ,  A23K1/00

CPC分类号： C12N1/36 ,  A61K39/012 ,  C12N1/10

公开(公告)号：EP4398919A1

公开(公告)日：2024-07-17

申请号：EP22868137.5

申请日：2022-09-09

申请人： Regents of the University of Minnesota

发明人： SALTZMAN, Daniel Alan ,  SCHOTTEL, Janet Louise ,  AUGUSTIN, Lance Bischoff

IPC分类号： A61K35/74 ,  A61K38/20 ,  A61P35/00 ,  C12N1/36

CPC分类号： Y02A50/30 ,  A61K35/74 ,  C12N1/36 ,  A61P35/00 ,  C12Y304/23049 ,  C12R2001/4220210501 ,  C07K14/255 ,  C12N9/52 ,  A61K45/06 ,  A61K38/204 ,  A61K31/661 ,  A61K31/427

公开(公告)号：EP2909229B1

公开(公告)日：2018-12-12

申请号：EP13777082.2

申请日：2013-10-17

申请人： INSERM (Institut National de la Santé et de la Recherche Médicale) ,  INSTITUT PASTEUR DE LILLE ,  Université de Lille

发明人： LOCHT, Camille ,  MIELCAREK, Nathalie ,  KAMMOUN, Hana

IPC分类号： C07K14/235 ,  C12N1/36 ,  A61K39/02 ,  A61K39/12 ,  A61K39/00 ,  A61K39/09

CPC分类号： C12N1/36 ,  A61K39/092 ,  A61K39/099 ,  A61K39/12 ,  A61K2039/522 ,  A61K2039/523 ,  A61K2039/543 ,  C07K14/235 ,  C12N2760/16134 ,  C12N2760/18534

摘要： The present invention relates to a recombinant genetically attenuated Bordetella strain expressing a hybrid protein comprising the N-terminal fragment of filamentous haemagglutinin (FHA) and a heterologous epitope or antigenic protein or protein fragment, different from FHA, wherein the gene coding for the native FHA protein is inactivated. The Bordetella strain is preferably a Bordetella pertussis strain, but may also be another Bordetella species, such as Bordetella bronchiseptica, Bordetella parapertussis or Bordetella avium. The invention further provides a life attenuated vaccine for the treatment of a mucosal or systemic infectious disease comprising a Bordetella strain as defined above intended to elicit a immune response against pathogens responsible for systemic or mucosal infections, including of the upper or lower respiratory tract. The present invention also relates to a method for prophylaxis of an infectious disease in a mammal, comprising administering to said mammal an effective amount of a vaccine comprising in a suitable vehicle a recombinant attenuated Bordetella strain expressing a fusion protein comprising the N-terminal fragment of filamentous haemagglutinin (FHA) and a heterologous epitome or antigenic protein or protein fragment, different from FHA, wherein the gene coding for the native FHA protein is inactivated.

公开(公告)号：EP3401388A1

公开(公告)日：2018-11-14

申请号：EP18178313.5

申请日：2013-12-06

申请人： Synthetic Genomics, Inc.

发明人： Bailey, Shaun ,  McCarren, Jay ,  Lieberman, Soyan Leung ,  Meuser, Jonathan E. ,  Romano, Anna E. ,  Yee, Daniel ,  Soriaga, Leah ,  Brown, Robert C. ,  Weissman, Joseph C. ,  Prince, Roger C. ,  Nielsen, Robert D. ,  Schwartz, Ariel S.

IPC分类号： C12N1/12 ,  C12N1/36 ,  C12N15/01 ,  C12N15/11 ,  C12N15/82 ,  C12N15/87 ,  C07K14/415 ,  C07K14/405

CPC分类号： C12N15/825 ,  C07K14/405 ,  C07K14/415 ,  C12N1/12 ,  C12N1/36 ,  C12N15/01 ,  C12N15/8269

摘要： Mutant photosynthetic microorganisms having reduced chlorophyll and increased photosynthetic efficiency are provided. The mutants have a locked in high light-acclimated phenotype, in which many of the photosynthetic parameters characteristic of high light acclimated wild type cells are found in the LIHLA mutants when acclimated to low light, such as reduced chlorophyll, reduced NPQ, higher qP, higher Ek, higher P max per unit chlorophyll with little to no reduction in P max per cell, and higher rates of electron transport through photosystem II over a wide range of light intensities. Provided herein are constructs for attenuating or disrupting genes are provided for generating mutants having the LIHLA phenotype. Also provided are methods of culturing LIHLA mutants for the production of biomass or other products.

公开(公告)号：EP3108016B1

公开(公告)日：2018-10-24

申请号：EP15709252.9

申请日：2015-02-16

申请人： Lesaffre et Compagnie

发明人： DESFOUGERES, Thomas ,  PIGNEDE, Georges ,  TECHEL, Jennifer

IPC分类号： C12R1/865 ,  C12N15/04 ,  C12P7/10 ,  C12N1/36 ,  C12N9/92 ,  C12N9/12 ,  C12N15/81

CPC分类号： C12N1/36 ,  C12N9/1205 ,  C12N9/92 ,  C12N15/81 ,  C12P7/10 ,  C12R1/865 ,  C12Y207/01006 ,  C12Y207/01017 ,  C12Y503/01005 ,  Y02E50/16 ,  Y02E50/17

公开(公告)号：EP2702141B1

公开(公告)日：2018-03-14

申请号：EP12775958.7

申请日：2012-04-25

申请人： California Institute of Technology

发明人： NEWMAN, Dianne K. ,  HUNTER, Ryan C.

IPC分类号： C12N1/36 ,  C12N1/20

CPC分类号： C12N1/20 ,  C12N1/36

摘要： Provided herein are methods and systems for interfering with viability of bacteria and related compounds and compositions.

公开(公告)号：EP3248614A1

公开(公告)日：2017-11-29

申请号：EP17178151.1

申请日：2011-12-22

申请人： ReVance Therapeutics, Inc.

发明人： WAUGH, Jacob ,  RUEGG, Curtis

IPC分类号： A61K39/02 ,  A61Q19/00 ,  A61K8/29 ,  A61K8/66 ,  A61K38/48 ,  A61Q19/08 ,  A61K8/20 ,  C12N1/36

CPC分类号： C12N1/36 ,  A61K8/0208 ,  A61K8/20 ,  A61K8/29 ,  A61K8/66 ,  A61K38/4893 ,  A61K2800/81 ,  A61Q19/08

摘要： This invention relates to methods and kits for safely removing and inactivating topical therapeutic or cosmetic compositions. The methods and kits according to the invention are particularly well suited for removing and inactivating highly toxic substances.

摘要翻译： 本发明涉及用于安全地除去和灭活局部治疗或美容组合物的方法和试剂盒。 根据本发明的方法和试剂盒特别适用于去除和灭活剧毒物质。

公开(公告)号：EP3099781A4

公开(公告)日：2017-10-04

申请号：EP15742642

申请日：2015-01-28

申请人： LANZATECH NEW ZEALAND LTD

发明人： HEIJSTRA BJORN DANIEL ,  AL-SINAWI BAKIR ,  SMITH LIAM BARRY ,  JENSEN RASMUS OVERGAARD ,  MITCHELL WAYNE PIERCE ,  KOEPKE MICHAEL

IPC分类号： C12N1/20 ,  C12P7/00 ,  C12P7/06 ,  C12P7/18 ,  C12P7/52 ,  C12P7/54

CPC分类号： C12N1/20 ,  C12N1/36 ,  C12P7/065 ,  C12P7/18 ,  C12P7/54 ,  C12R1/145 ,  Y02E50/17

公开(公告)号：EP3198001A1

公开(公告)日：2017-08-02

申请号：EP15844910.8

申请日：2015-09-22

申请人： Novozymes A/S

发明人： DIAO, Liuyang ,  SUTTON, Kate Brandon ,  JIANG, Yu ,  YANG, Sheng ,  QIAN, Fenghui ,  LIU, Yingmiao

IPC分类号： C12N1/19 ,  C12N1/22 ,  C12P1/00 ,  C12P7/06

CPC分类号： C12P7/14 ,  C07K14/395 ,  C12N1/36 ,  C12N9/1022 ,  C12N9/1205 ,  C12N9/90 ,  C12N15/52 ,  C12P7/10 ,  C12R1/865 ,  C12Y202/01001 ,  C12Y202/01002 ,  C12Y207/01017 ,  C12Y501/03001 ,  C12Y503/01005 ,  C12Y503/01006 ,  Y02E50/16 ,  Y02E50/17

摘要： Processes for producing ethanol comprise saccharifying cellulosic material with a cellulolytic enzyme composition and fermenting the saccharified cellulosic material with a fermenting microorganism to produce ethanol. The fermenting organism is Saccharomyces cerevisiae CIBTS1260 (deposited under Accession No. NRRL Y-50973 at the Agricultural Research Service Culture Collection (NRRL), Illinois 61604 U.S.A.) or a fermenting organism that has properties that the same or about the same as that of Saccharomyces cerevisiae CIBTS1260).

摘要翻译： 生产乙醇的方法包括用纤维素分解酶组合物糖化纤维素材料并用发酵微生物发酵糖化纤维素材料以产生乙醇。 发酵生物是酿酒酵母CIBTS1260（保藏号为NRRL Y-50973，在农业研究服务培养物保藏中心（NRRL），伊利诺斯州61604）或发酵生物，其具有与酵母属相同或大致相同的性质 酿酒酵母CIBTS1260）。