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公开(公告)号：EP3738434B1
公开(公告)日：2023-09-13
申请号：EP20167746.5
申请日：2012-12-28
发明人： METCALF, Brian , CHUANG, Chihyuan , WARRINGTON, Jeffrey , PAULVANNAN, Kumar , JACOBSON, Matthew , HUA, Lan , MORGAN, Bradley
IPC分类号： A01N35/00 , A61K31/11 , C07D213/80 , C07D215/14 , C07C69/76 , C07D231/56 , C07D401/04 , C07D471/04 , C07D257/04 , C07D487/04 , C07D211/62 , C07D213/30 , C07C65/21
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公开(公告)号：EP4136076A1
公开(公告)日：2023-02-22
申请号：EP21717897.9
申请日：2021-04-14
发明人： BERCHTOLD, Stefan , GALLEY, Guido , GROEBKE ZBINDEN, Katrin , GUBA, Wolfgang , HUNZIKER, Daniel , KRUMM, Danny
IPC分类号： C07D233/60 , C07D239/36 , C07D249/08 , C07D295/145 , C07C65/21 , C07C233/55 , A61P29/00 , A61K31/513
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公开(公告)号：EP3864001A1
公开(公告)日：2021-08-18
申请号：EP19809143.1
申请日：2019-10-10
申请人： BASF AS
IPC分类号： C07C59/64 , C07C63/04 , C07C63/64 , C07C65/21 , C07C65/28 , C07C65/32 , C07C229/54 , C07C233/54 , C07C235/46 , C07C317/44 , C07C323/62 , A61P1/16 , A61P3/00 , A61P3/04 , A61P3/06
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4.发明公开
公开(公告)号：EP3738434A1
公开(公告)日：2020-11-18
申请号：EP20167746.5
申请日：2012-12-28
发明人： METCALF, Brian , CHUANG, Chihyuan , WARRINGTON, Jeffrey , PAULVANNAN, Kumar , JACOBSON, Matthew , HUA, Lan , MORGAN, Bradley
IPC分类号： A01N35/00 , A61K31/11 , C07D213/80 , C07D215/14 , C07C69/76 , C07D231/56 , C07D401/04 , C07D471/04 , C07D257/04 , C07D487/04 , C07D211/62 , C07D213/30 , C07C65/21
摘要： Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
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5.发明公开
公开(公告)号：EP3679012A1
公开(公告)日：2020-07-15
申请号：EP18778763.5
申请日：2018-09-07
发明人： YANG, Syaulan S. , LEE, Kuang Yuan , LIU, Meng Hsien , JIANG, Yan-Feng , FAN, Yu-Shiou , CHEN, Chi-Han , LIU, Sheng Hung
IPC分类号： C07C259/10 , C07C65/21 , C07C271/30 , C07C275/30 , C07C311/16 , C07C311/51 , C07C317/18 , C07C217/76 , C07C233/66 , C07C233/67 , C07C49/517
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6.发明授权
公开(公告)号：EP2746248B1
公开(公告)日：2018-05-30
申请号：EP12823807.8
申请日：2012-08-08
申请人： Kuraray Co., Ltd.
IPC分类号： B01D53/02 , C07C63/28 , B01D53/04 , B01J20/22 , B01J20/30 , B01J20/34 , C07C205/57 , C01B3/56 , C07C65/21 , C07F13/00 , C07F3/06
CPC分类号： B01D53/0462 , B01D53/02 , B01D53/047 , B01D2253/204 , B01D2256/18 , B01D2257/102 , B01D2257/104 , B01D2257/304 , B01D2257/406 , B01D2257/502 , B01D2257/504 , B01D2257/702 , B01D2257/80 , B01J20/223 , B01J20/226 , B01J20/3085 , B01J20/3425 , B01J20/3483 , B01J20/3491 , C01B3/56 , C01B2203/042 , C01B2203/043 , C01B2203/0475 , C07C63/28 , C07C65/21 , C07F3/003 , Y02C10/08 , Y02P20/152 , Y02P20/51 , Y02P30/30
摘要： The problem of providing a metal complex having excellent gas adsorption performance, gas storage performance, and gas separation performance is solved by a metal complex comprising a dicarboxylic acid compound (I) including 20 to 99 mole % of a dicarboxylic acid compound (I-1) selected from terephthalic acid derivatives having an electron-donating group in the 2nd position such as 2-methoxyterephthalic acid, 2-methylterephthalic acid, and terephthalic acid, and 80 to 1 mole % of a dicarboxylic acid compound (I-2) selected from terephthalic acid derivatives having an electron-withdrawing group in the 2nd position such as 2-nitroterephthalic acid, 2-fluoroterephthalic acid, 2-chloroterephthalic acid, 2-bromoterephthalic acid, and 2-iodoterephthalic acid; at least one kind of metal ion selected from metal ions belonging to Group 2 and Groups 7 to 12 of the periodic table; and an organic ligand capable of bidentate binding to the metal ion.
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7.发明授权SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION 有权取代的苯甲醛化合物及其用于增加组织氧化的方法
公开(公告)号：EP2797416B1
公开(公告)日：2017-08-09
申请号：EP12862525.8
申请日：2012-12-28
发明人： METCALF, Brian , CHUANG, Chihyuan , WARRINGTON, Jeffrey , PAULVANNAN, Kumar , JACOBSON, Matthew P. , HUA, Lan , MORGAN, Bradley
IPC分类号： A01N35/00 , A61K31/11 , C07D213/80 , C07D215/14 , C07C69/76 , C07D231/56 , C07D401/04 , C07D471/04 , C07D257/04 , C07D487/04 , C07D211/62 , C07D213/30 , C07C65/21 , C07C65/30 , A61K31/192 , A61K31/235 , A61K31/41 , A61K31/416 , A61K31/437 , A61K31/4406 , A61K31/4439
CPC分类号： A61K31/4985 , A61K31/192 , A61K31/235 , A61K31/41 , A61K31/416 , A61K31/437 , A61K31/4406 , A61K31/4439 , A61K31/445 , A61K31/47 , C07C65/30 , C07C69/76 , C07D211/62 , C07D213/30 , C07D213/80 , C07D215/14 , C07D231/56 , C07D257/04 , C07D401/04 , C07D471/04 , C07D487/04
摘要： Provided are substituted benzaldehydes and derivatives thereof of formula (I) that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
摘要翻译： 提供了作为血红蛋白的变构调节剂的式（I）的取代苯甲醛及其衍生物，其制备方法和中间体，包含该调节剂的药物组合物，以及它们用于治疗由血红蛋白介导的病症的方法和将从其受益 增加组织氧合。
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8.发明授权INTERMEDIATE FILM OF LAMINATED SAFETY GLASS WITH ANTIGLARE FUNCTION AND NOVEL NEODYMIUM COMPOUND 有权BETWEEN镀膜玻璃具有防眩光功能和新的钕复合膜
公开(公告)号：EP1840096B1
公开(公告)日：2015-07-29
申请号：EP06711912.3
申请日：2006-01-18
发明人： TAKAGI, Shunji , FUJIO, Yoshiharu
IPC分类号： B32B17/10 , B60J1/00 , C03C27/12 , C07C51/41 , C07C53/124 , C07C59/70 , C07C63/04 , C07C65/21 , C07C69/80 , G02B5/22
CPC分类号： B32B17/10036 , B32B17/10761 , C07C51/412 , C07C53/124 , C07C59/70 , C07C63/04 , C07C65/21 , C07C67/30 , C07C69/80 , G02B5/223 , Y10T428/31627 , Y10T428/3163 , Y10T428/31645
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9.发明授权
公开(公告)号：EP1792888B1
公开(公告)日：2011-07-06
申请号：EP05774659.6
申请日：2005-08-23
发明人： NAGASAWA, Masaaki Zeria Pharmaceutical Co., Ltd. , ASAMI, Kazuyasu , NAKAO, Ryu Zeria Pharmaceutical Co., Ltd. , TANAKA, Nobuyuki Zeria Pharmaceutical Co., Ltd. , AIDA, Yoshiyuki Zeria Pharmaceutical Co., Ltd.
IPC分类号： C07C51/377 , C07C65/21 , C07C67/08 , C07C67/11 , C07C69/92 , C07D277/20 , C07D277/56
CPC分类号： C07C69/92 , C07C51/347 , C07C51/377 , C07C67/08 , C07C205/60 , C07D277/46 , C07D277/56 , C07C65/05
摘要： Disclosed is a selective demethylation process of a 2-methoxy group. Specifically disclosed is a method for producing a compound represented by the formula (7) below through the following reactions.
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10.发明公开INTERMEDIATES AND PROCESS FOR THE PRODUCTION OF OPTICALLY ACTIVE QUINOLONECARBOXYLIC ACID DERIVATIVES 审中-公开中间体和方法制备光学活性的喹诺酮羧酸衍生物
公开(公告)号：EP1632482A4
公开(公告)日：2009-10-28
申请号：EP04745589
申请日：2004-06-04
申请人： DAIICHI SEIYAKU CO
发明人： MUTO MAKOTO , MIURA MANABU , KITAGAWA YUTAKA
IPC分类号： C07D215/56 , A01N43/42 , C07C51/00 , C07C51/60 , C07C65/21 , C07C221/00 , C07C225/14 , C07C225/16
CPC分类号： C07D215/56 , A01N43/42 , C07C51/00 , C07C65/21 , C07C225/16 , C07C255/43 , C07C2601/02 , C07D215/54
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