Casein nanoparticle
    10.
    发明专利
    Casein nanoparticle 审中-公开
    CASEIN NANOPARTICLE

    公开(公告)号:JP2010132609A

    公开(公告)日:2010-06-17

    申请号:JP2008310530

    申请日:2008-12-05

    摘要: PROBLEM TO BE SOLVED: To provide a nanoparticle which can be manufactured without using a surfactant or a synthetic polymer and can be controlled over the size and besides is acidic and stable, and moreover envelops therein an active substance and has a positive charge, and to provide a method for manufacturing the same. SOLUTION: The casein particle is positive in the zeta potential. The particle is made by the following processes (a) and (b): (a) a process of mixing casein into an acidic aqueous medium of not less than pH 0.5 to less than pH 7; and (b) a process, while stirring the solution obtained in the above process (a), of increasing a pH of the solution from an isoelectric point of the casein to a pH apart therefrom by ±pH 0.5 or more. COPYRIGHT: (C)2010,JPO&INPIT

    摘要翻译: 要解决的问题:提供可以在不使用表面活性剂或合成聚合物的情况下制造的纳米颗粒,并且可以在大小上控制,此外还具有酸性和稳定性,并且还包含活性物质并具有正电荷 ,并提供其制造方法。

    解决方案:酪蛋白颗粒在ζ电位为正。 颗粒通过以下方法(a)和(b)制备:(a)将酪蛋白混合到不低于pH5.5至小于pH7的酸性水性介质中的方法; 和(b)在搅拌上述方法(a)中获得的溶液的同时,将溶液的pH从酪蛋白的等电点提高至pH为0.5以上的过程。 版权所有(C)2010,JPO&INPIT