公开(公告)号：US10155966B2

公开(公告)日：2018-12-18

申请号：US15013366

申请日：2016-02-02

Applicant: Inbicon A/S

Inventor： Borge Holm Christensen ,  Lena Holm Gerlach

IPC: B01J19/24 ,  D21C9/18 ,  C12P7/10 ,  C08B15/00 ,  C08B37/00 ,  C08H7/00 ,  C08H8/00 ,  C13B20/16 ,  C13K1/02 ,  C12P7/56 ,  C12P21/00 ,  C12M1/00 ,  C12M1/33 ,  C08B1/00 ,  C12P7/14 ,  C12P19/02 ,  C12P19/14

Abstract: The present invention provides an apparatus and a method for conversion of cellulosic material, such as chopped straw and corn stover, and household waste, to ethanol and other products. The cellulosic material is subjected to continuous hydrothermal pre-treatment without addition of chemicals, and a liquid and a fiber fraction are produced. The fiber fraction is subjected to enzymatic liquefaction and saccharification. The method of the present invention comprises: performing the hydrothermal pre-treatment by subjecting the cellulosic material to at least one soaking operation, and conveying the cellulosic material through at least one pressurized reactor, and subjecting the cellulosic material to at least one pressing operation, creating a fiber fraction and a liquid fraction; selecting the temperature and residence time for the hydrothermal pretreatment, so that the fibrous structure of the feedstock is maintained and at least 80% of the lignin is maintained in the fiber fraction.

公开(公告)号：US20150037856A1

公开(公告)日：2015-02-05

申请号：US14350081

申请日：2011-10-06

Applicant: Jan Larsen ,  Martin Dan Jeppesen

Inventor： Jan Larsen ,  Martin Dan Jeppesen

IPC: C12P7/14

CPC classification number: C12P7/14 ,  C12P7/00 ,  C12P7/06 ,  C12P19/00 ,  Y02E50/17

Abstract: Methods are provided for improved processing of lignocellulosic biomass. Hydrothermally pretreated lignocellulosic biomass is subject to separate hydrolysis and fermentation (SHF) or prehydrolysed and subject to simultaneous saccharification and fermentation (SSF) at high initial loadings of cellulase enzymes, at least 15 FPU/g DM. The cellulase enzymes are subsequently recycled and used in subsequent hydrolysis cycles along with a lower dose supplementation of fresh enzyme. Loss of enzyme activity between hydrolysis cycles is offset by improved overall process advantage.

Abstract translation: 提供了改进木质纤维素生物质处理的方法。 水热预处理的木质纤维素生物质经受单独的水解和发酵（SHF）或预水解，并在纤维素酶的高初始负载下进行同时糖化和发酵（SSF），至少15FPU / g DM。 随后将纤维素酶再循环使用，随后进行水解循环，同时补充新鲜的酶。 在水解循环之间的酶活性的损失被改进的整体工艺优点所抵消。

公开(公告)号：US08187849B2

公开(公告)日：2012-05-29

申请号：US12808746

申请日：2008-12-18

Applicant: Jan Larsen

Inventor： Jan Larsen

IPC: C12P7/10 ,  C12P7/08 ,  C12P7/06

CPC classification number: C12P7/06 ,  A01N43/08 ,  A01N61/00 ,  A01N65/00 ,  A01N65/44 ,  C12N1/22 ,  C12P7/10 ,  C12P2201/00 ,  Y02E50/16 ,  Y02E50/17

Abstract: A range of concentrations exists in which fermentation inhibitors derived from pretreatment of lignocellulosic feed stocks inhibit growth of lactic acid bacteria without affecting fermentive yeast. By optimizing levels of fermentation inhibitors to fall within this range, yeast fermentations of lignocellulosic biomass can be conducted under non-sterile conditions with ethanol yields comparable to those achieved under sterile conditions. Optimised inhibitor levels can be achieved by controlling the water/biomass ratio of a lignocellulosic biomass during and after pretreatment, for example by washing the fiber fraction of a previously pretreated lignocellulosic biomass with a pre-defined amount of fresh water or recycled process solutions. Crude extracts of liquid fraction or process solutions from pretreatment of lignocellulosic biomass can also provide an effective anti-bacterial treatment for first generation starch fermentations.

Abstract translation: 存在一定范围的浓度，其中衍生自木质纤维素原料的预处理的发酵抑制剂抑制乳酸菌的生长而不影响发酵酵母。 通过优化发酵抑制剂的含量落在此范围内，木质纤维素生物质的酵母发酵可以在非无菌条件下进行，乙醇产量与在无菌条件下达到的相似。 优化的抑制剂水平可以通过在预处理期间和之后控制木质纤维素生物质的水/生物量比来实现，例如通过用预定量的淡水或再循环的处理溶液洗涤先前预处理的木质纤维素生物质的纤维部分。 来自木质纤维素生物质预处理的液体馏分或处理溶液的粗提取物也可为第一代淀粉发酵提供有效的抗菌处理。

公开(公告)号：US08187848B2

公开(公告)日：2012-05-29

申请号：US13132926

申请日：2009-12-17

Applicant: Jan Larsen ,  Mai Østergaard Petersen

Inventor： Jan Larsen ,  Mai Østergaard Petersen

IPC: C12P7/06

CPC classification number: C12P19/14 ,  C12P7/10 ,  C12P2201/00 ,  Y02E50/16 ,  Y02E50/17

Abstract: The invention relates to methods of processing ensiled biomass for production of bioethanol or other fermentation products and, in particular, to methods that do not require expensive pretreatment (e.g. heat or chemical pretreatment).

Abstract translation: 本发明涉及加工用于生产生物乙醇或其他发酵产物的生物质的方法，特别涉及不需要昂贵的预处理（例如热或化学预处理）的方法。

公开(公告)号：US12188070B2

公开(公告)日：2025-01-07

申请号：US16347091

申请日：2017-11-06

Applicant: Inbicon A/S

Inventor： Martin Dan Jeppesen ,  Jan Larsen ,  Kit Haubjerg Mogensen ,  Anna Frederike Gossmann ,  Anna Granly Hansen ,  Laila Thirup ,  Lars Villadsgaard Toft ,  Hanne Risbjerg Sørensen

IPC: C12P19/02 ,  C07G1/00 ,  C08L95/00 ,  C12P7/10 ,  C12P19/14 ,  C13K1/02 ,  C13K13/00

Abstract: A method for providing a C5/C6 product from a lignocellulosic material is disclosed, said method comprising the steps: (i) pretreatment of the lignocellulosic material; (ii) solid/liquid separation of the pretreated lignocellulosic material from step (a) into a first solid fraction and a first liquid fraction; (iii) enzymatic fiber hydrolysis of said first solid fraction from step (b) by use of an enzyme composition capable of degrading lignocellulosic material, thereby providing a C5/C6 fiber slurry comprising C5 and/or C6 sugars; (iv) solid/liquid separation of the C5/C6 fiber slurry from step (c) into a second solid fraction and a second liquid fraction; and optionally (v) combining said first liquid fraction and said second liquid fraction for enzymatic mixed sugar hydrolysis (MSH), whereby a MSH C5/C6 product is provided.

公开(公告)号：US20240182649A1

公开(公告)日：2024-06-06

申请号：US18403329

申请日：2024-01-03

Applicant: Inbicon A/S

Inventor： Duy Michael Lee ,  Mia Frosch Mogensbæk Foverskov

IPC: C08H8/00 ,  C08L7/02 ,  C08L9/00 ,  C08L9/06 ,  C08L19/00 ,  C08L53/02 ,  C08L95/00 ,  C08L97/00 ,  E01C5/12 ,  E01C7/35

CPC classification number: C08H8/00 ,  C08L7/02 ,  C08L9/00 ,  C08L9/06 ,  C08L19/003 ,  C08L53/02 ,  C08L95/00 ,  C08L97/005 ,  E01C5/12 ,  E01C7/353 ,  C08L2555/52 ,  C08L2555/64 ,  C08L2555/82 ,  C08L2555/84 ,  C08L2555/86 ,  Y02A30/30

Abstract: The current invention concerns composition comprising bitumen, one or more plasticity modifying agent(s), and lignin, as well as methods and uses related to such compositions. In particular, compositions are disclosed with improved properties, such as mixing properties.

公开(公告)号：US20240102064A1

公开(公告)日：2024-03-28

申请号：US18523358

申请日：2023-11-29

Applicant: Inbicon A/S

Inventor： Jan Larsen ,  Niels Nielsen Poulsen ,  Martin Dan Jeppesen ,  Kit Kellebjerg Mogensen

IPC: C12P19/14 ,  C12P7/10 ,  C12P19/02 ,  C13K1/02 ,  C13K13/00 ,  D21C1/04 ,  D21C3/04

CPC classification number: C12P19/14 ,  C12P7/10 ,  C12P19/02 ,  C13K1/02 ,  C13K13/002 ,  D21C1/04 ,  D21C3/04 ,  C12P2201/00 ,  Y02E50/10

Abstract: The invention relates, in general, to methods of processing Lignocellulosic biomass to fermentable sugars and to methods that rely on hydrothermal pretreatment. Xylose monomer yields comparable to those achieved using two-stage pretreatments can be achieved from soft Lignocellulosic biomass feedstocks by pretreasting to very low severity in a single-stage pressurized hydrothermal pretreatment, followed by enzymatic hydrolysis to release xylose retained in the solid state. In some embodiments, pretreated biomass is separated into a solid fraction and a liquid fraction, the solid fraction subjected to enzymatic hydrolysis, and the separated liquid fraction subsequently mixed with the hydrolysed solid fraction.

公开(公告)号：US20210348202A1

公开(公告)日：2021-11-11

申请号：US17329960

申请日：2021-05-25

Applicant: Inbicon A/S

Inventor： Jan Larsen ,  Niels Nielsen Poulsen ,  Martin Dan Jeppesen ,  Kit Kellebjerg Mogensen

IPC: C12P19/14 ,  D21C1/04 ,  C12P7/10 ,  D21C3/04 ,  C12P19/02 ,  C13K1/02 ,  C13K13/00

Abstract: The invention relates, in general, to methods of processing Lignocellulosic biomass to fermentable sugars and to methods that rely on hydrothermal pretreatment. Xylose monomer yields comparable to those achieved using two-stage pretreatments can be achieved from soft Lignocellulosic biomass feedstocks by pretreasting to very low severity in a single-stage pressurized hydrothermal pretreatment, followed by enzymatic hydrolysis to release xylose retained in the solid state. In some embodiments, pretreated biomass is separated into a solid fraction and a liquid fraction, the solid fraction subjected to enzymatic hydrolysis, and the separated liquid fraction subsequently mixed with the hydrolysed solid fraction.

公开(公告)号：US20170009261A9

公开(公告)日：2017-01-12

申请号：US14253890

申请日：2014-04-16

Applicant: Inbicon A/S

Inventor： Jan Larsen

IPC: C12P7/06

CPC classification number: C12P7/06 ,  A01N65/44 ,  C12N1/16 ,  C12N1/22 ,  C12P7/10 ,  Y02E50/16 ,  Y02E50/17

Abstract: A range of concentrations exists in which fermentation inhibitors derived from pretreatment of lignocellulosic feed stocks inhibit growth of lactic acid bacteria without affecting fermentive yeast. By optimizing levels of fermentation inhibitors to fall within this range, yeast fermentations of lignocellulosic biomass can be conducted under non-sterile conditions with ethanol yields comparable to those achieved under sterile conditions. Optimised inhibitor levels can be achieved by controlling the water/biomass ratio of a lignocellulosic biomass during and after pretreatment, for example by washing the fiber fraction of a previously pretreated lignocellulosic biomass with a pre-defined amount of fresh water or recycled process solutions. Crude extracts of liquid fraction or process solutions from pretreatment of lignocellulosic biomass can also provide an effective anti-baterial treatment for first generation starch fermentations.

Abstract translation: 存在一定范围的浓度，其中衍生自木质纤维素原料的预处理的发酵抑制剂抑制乳酸菌的生长而不影响发酵酵母。 通过优化发酵抑制剂的含量落在此范围内，木质纤维素生物质的酵母发酵可以在非无菌条件下进行，乙醇产量与在无菌条件下达到的相似。 优化的抑制剂水平可以通过在预处理期间和之后控制木质纤维素生物质的水/生物量比来实现，例如通过用预定量的淡水或再循环的处理溶液洗涤先前预处理的木质纤维素生物质的纤维部分。 来自木质纤维素生物质预处理的液体馏分或处理溶液的粗提取物也可为第一代淀粉发酵提供有效的抗物质处理。

公开(公告)号：US20160215448A1

公开(公告)日：2016-07-28

申请号：US14910531

申请日：2014-08-11

Applicant: INBICON A/S

Inventor： Jesper Dohrup ,  Brian Eskesen ,  Kit Kellebjerg Mogensen

IPC: D21C1/10 ,  D21C1/02

CPC classification number: D21C1/10 ,  B01J3/002 ,  B01J3/008 ,  B01J3/02 ,  B01J3/04 ,  B01J2219/00058 ,  B01J2219/00065 ,  B01J2219/00067 ,  B01J2219/00162 ,  B01J2219/00177 ,  B01J2219/0018 ,  B01J2219/00182 ,  B01J2219/00189 ,  C10L5/44 ,  C10L9/086 ,  C12P2201/00 ,  D21C1/02 ,  Y02E50/10 ,  Y02E50/30

Abstract: Provided is a discharge device for discharging pretreated biomass from a pressurized reactor. The device comprises: a vessel having an opening to a high pressure region at the top, and configured to be connected with a pressurized biomass pretreatment device; one or more inlet openings situated along the sides of the vessels through which water or liquid may be added; an orifice or valve at a lower part of said vessel, said orifice or valve being configured to eject pretreated biomass, optionally into a pipeline. The discharge device is characterised in that it comprises mechanical agitation means, said agitation means comprising an agitation element arranged in the interior of said vessel at a lower part of said vessel, and being configured to provide agitation of the content of said vessel, wherein said agitation means being adapted to withstand a pressure in the interior of a said vessel of 10 bar or more. The agitation means provides for a temperature equalization within a specific vertical range of heights of an aqueous slurry present in said vessel, thereby eliminating disadvantages of the prior art devices and methods.

Abstract translation: 提供一种用于从加压反应器中排出预处理的生物质的排放装置。 该装置包括：容器，其具有在顶部处于高压区域的开口，并且构造成与加压的生物质预处理装置连接; 沿着容器侧面设置的一个或多个入口开口，水或液体可以通过该入口开口; 在所述容器的下部的孔或阀，所述孔或阀构造成可任选地排出预处理的生物质到管道中。 排放装置的特征在于它包括机械搅拌装置，所述搅拌装置包括在所述容器的下部设置在所述容器的内部的搅拌元件，并且构造成提供所述容器的内容物的搅拌，其中所述 搅拌装置适于承受10巴或更多的所述容器内部的压力。 搅拌装置提供在所述容器中存在的含水浆料的特定垂直垂直范围内的温度均衡，从而消除现有技术装置和方法的缺点。