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公开(公告)号:US08722656B2
公开(公告)日:2014-05-13
申请号:US13459851
申请日:2012-04-30
申请人: Brian A. Duclos , Edmund L. Ellsworth , Richard A. Ewin , Paul D. Johnson , Timothy A. Johnson , Graham M. Kyne , Susan M. K. Sheehan , Rajendran Vairagoundar
发明人: Brian A. Duclos , Edmund L. Ellsworth , Richard A. Ewin , Paul D. Johnson , Timothy A. Johnson , Graham M. Kyne , Susan M. K. Sheehan , Rajendran Vairagoundar
IPC分类号: A61K31/545 , C07D501/60
CPC分类号: C07D501/24
摘要: The present invention provides novel cephalosporin derivatives of formula I, their analogues, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.
摘要翻译: 本发明提供式I的新型头孢菌素衍生物,其类似物,其用于治疗哺乳动物感染的药物组合物,含有这些新化合物的药物组合物,以及制备这些化合物的方法。
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公开(公告)号:US20140088046A1
公开(公告)日:2014-03-27
申请号:US14018993
申请日:2013-09-05
申请人: Denis Billen , Michael Curtis , Richard Andrew Ewin , Richard M. Goodwin , Paul D. Johnson , Timothy Allan Johnson , Graham M. Kyne , Todd M. Maddux , Susan Mary Kult Sheehan , Rajendran Vairagoundar
发明人: Denis Billen , Michael Curtis , Richard Andrew Ewin , Richard M. Goodwin , Paul D. Johnson , Timothy Allan Johnson , Graham M. Kyne , Todd M. Maddux , Susan Mary Kult Sheehan , Rajendran Vairagoundar
IPC分类号: C07D213/40 , C07D261/08 , C07D409/04 , C07D213/64 , C07F9/6558 , C07F9/58 , C07D213/50 , C07D333/24 , C07D333/22 , C07D401/06 , C07D277/56 , C07D285/12 , C07D405/04 , C07D401/04
CPC分类号: C07D213/40 , C07D213/50 , C07D213/56 , C07D213/57 , C07D213/64 , C07D231/12 , C07D261/08 , C07D277/30 , C07D277/56 , C07D285/12 , C07D333/22 , C07D333/24 , C07D401/04 , C07D401/06 , C07D405/04 , C07D405/06 , C07D409/04 , C07D417/04 , C07F7/2208 , C07F9/58 , C07F9/65586
摘要: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.
摘要翻译: 本发明提供了新型酚酞衍生物,其用于治疗哺乳动物感染的药物组合物,含有这些新化合物的药物组合物,以及制备这些化合物的方法。
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公开(公告)号:US20130221047A1
公开(公告)日:2013-08-29
申请号:US13385626
申请日:2012-02-27
申请人: Paul D. Johnson
发明人: Paul D. Johnson
CPC分类号: A45F3/14 , A45C13/30 , A45C2013/306 , A45F5/021 , A45F2003/142 , B62J7/08 , B62J11/00 , Y10T24/318
摘要: A strap assembly providing a means to secure large and varying sized articles to the back underside seat rails of a bicycle seat without adding weight or bulk to the bicycle. An attaching loop properly positions the strap assembly to the seat rail, aids in cinching the strap assembly tight and keeps the strap assembly attached to the seat rail when not in use. The attaching loop never permanently tightens so the strap assembly is always easily removed. The strap assembly is small and light enough to fit in a rider's jersey pocket or under-seat tool bag when not in use. The strap assembly negates the need for bicycle equipment bags. The strap assembly can also secure articles to backpacks, garment belts, car-top racks, kayak grab rails, tool boxes, bags and luggage.
摘要翻译: 一种带组件,其提供了将大型和变化尺寸的物品固定到自行车座椅的后侧座椅导轨上的装置,而不会对自行车增加重量或体积。 连接环将带组件正确地定位到座椅导轨上,有助于紧固束带组件,并且在不使用时将带组件固定在座椅导轨上。 连接环永远不会永久拧紧,因此皮带组件总是易于拆卸。 皮带组合体积小巧且足够轻巧,可以在不使用时装入骑手的平针织口袋或座椅下工具袋中。 带组件不需要自行车设备袋。 带组件还可以将物品固定到背包,服装带,车顶架,皮划艇轨道,工具箱,袋和行李箱上。
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公开(公告)号:US08397565B1
公开(公告)日:2013-03-19
申请号:US13087433
申请日:2011-04-15
申请人: Daniel R Dillon , Paul D Johnson , Frank W Huber
发明人: Daniel R Dillon , Paul D Johnson , Frank W Huber
CPC分类号: G01P1/02 , G01F1/46 , G01P13/025
摘要: A high response air angle probe to measure a flow direction in an air flow near or above Mach one. The probe is rotatably secured within an assembly with marking to indicate when a desired position of the probe within the air flow has been found. The probe includes a row of three high response pressure transducers on a leading edge region to detect when the probe is at a certain position within the air flow.
摘要翻译: 一个高响应气流角度探头,用于测量马赫一附近或以上气流中的流动方向。 探针可旋转地固定在具有标记的组件中,以指示何时已经发现探针在空气流中的期望位置。 探头在前缘区域上包括一排三个高响应压力传感器,以检测探头何时位于空气流中的某个位置。
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公开(公告)号:US5852195A
公开(公告)日:1998-12-22
申请号:US809224
申请日:1996-11-04
申请人: Karen Rene Romines , Gordon L. Bundy , Theresa M. Schwartz , Ruben A. Tommasi , Joseph W. Strohbach , Steven Ronald Turner , Suvit Thaisrivongs , Paul Adrian Aristoff , Paul D. Johnson , Harvey Irving Skulnick , Louis L. Skaletzky , David John Anderson , Joel Morris , Ronald B. Gammill , George P. Luke
发明人: Karen Rene Romines , Gordon L. Bundy , Theresa M. Schwartz , Ruben A. Tommasi , Joseph W. Strohbach , Steven Ronald Turner , Suvit Thaisrivongs , Paul Adrian Aristoff , Paul D. Johnson , Harvey Irving Skulnick , Louis L. Skaletzky , David John Anderson , Joel Morris , Ronald B. Gammill , George P. Luke
IPC分类号: A61K31/365 , A61K31/366 , A61K31/415 , A61K31/425 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/47 , A61K31/4709 , A61K31/505 , A61K31/506 , A61K31/54 , A61P31/12 , C07D20060101 , C07D309/32 , C07D309/38 , C07D309/40 , C07D311/02 , C07D311/08 , C07D311/74 , C07D311/94 , C07D401/12 , C07D403/12 , C07D405/00 , C07D405/12 , C07D405/14 , C07D407/00 , C07D409/00 , C07D417/00 , C07D417/12
CPC分类号: C07D405/12 , C07D309/32 , C07D309/38 , C07D311/02 , C07D311/74 , C07D405/14
摘要: The present invention relates to compounds of formulae (I) and (II) which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-ones, 4-hydroxy-cycloalkyl�b!pyran-2-ones, and derivatives thereof, useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus, wherein R.sub.10 and R.sub.20 taken together are formulae (III) and (IV). ##STR1##
摘要翻译: PCT No.PCT / US95 / 05219 Sec。 371日期:1996年11月4日 102(e)日期1996年11月4日PCT提交1995年5月4日PCT公布。 公开号WO95 / 30670 PCT 日期:1月16日,1995本发明涉及式(I)和(II)的化合物,其为吡喃-2-酮,5,6-二氢 - 吡喃-2-酮,4-羟基 - 苯并吡喃-2-酮, 可用于抑制感染所述逆转录病毒的哺乳动物细胞中的逆转录病毒的4-羟基 - 环烷基[b]吡喃-2-酮及其衍生物,其中R 10和R 20一起为式(III)和(IV)。 (一)图像(二)<图像>(三)<图像>(四)
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公开(公告)号:US5438617A
公开(公告)日:1995-08-01
申请号:US223107
申请日:1994-04-04
IPC分类号: H01R13/66 , H01R13/703 , H04Q1/14 , H04M1/00
CPC分类号: H01R13/7035 , H04Q1/142 , H01R13/6658
摘要: A low frequency (1-3 Mbps) telecommunication network cross-connect panel 10 is described for cross-connecting eighty-four fiber multiplex circuit elements 12 and eighty-four digital loop carrier circuits 14. The panel 10 has a housing 16 for supporting twenty-one modules 30 in which each module 30 has an upper patch access section 34 and a lower cross-connection field section 36. The upper section 34 includes two sets of front access wire-wrap pins 50 and 56 for providing front patch access capability utilizing a female patch plug 130. The lower cross-connection section 36 includes two sets of cross-connect pins 62 and 68 providing eighty-four columns of eight pins each defining a cross-connect field. Each module 30 includes a printed circuit board 40 for physically electrically interconnecting the pins through electrical circuits 100, 102, 104, and 106 as illustrated in FIG. 5. The printed circuit board includes an electrical switch means 108 that is a make-before-break arrangement in which front access contact is made prior to interrupting the circuit 100, 102, 104 and 106.
摘要翻译: 描述了低频(1-3Mbps)电信网络交叉连接面板10用于交叉连接八十四个光纤复用电路元件12和八十四个数字环路载波电路14.面板10具有用于支持二十 - 一个模块30,其中每个模块30具有上部补片存取部分34和下部交叉连接磁场部分36.上部分34包括两组前进导线缠绕销50和56,用于提供利用 下交叉连接部分36包括两组交叉连接销62和68,它们提供八个四列八个销,每个定义交叉连接字段。 每个模块30包括印刷电路板40,用于通过电路100,102,104和106将引脚物理上电互连,如图1所示。 印刷电路板包括电开关装置108,其是在断开电路100,102,104和106之前进行前接触触点的前断开装置。
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公开(公告)号:US5432847A
公开(公告)日:1995-07-11
申请号:US219766
申请日:1994-03-29
IPC分类号: H01R13/703 , H04Q1/14 , H04M3/00
CPC分类号: H01R13/7035 , H04Q1/13 , H01R2107/00 , H01R24/66
摘要: A low frequency telecommunication digital network interface patch panel 10 is described having the capability of terminating and providing front access to one-hundred-sixty-eight low frequency network elements 12 and 14 that generate low frequency signals between 1 and 3 Mbps. The panel has a housing with twenty-one adjacent modules; each module being one inch in width and having an upper set of wire-wrap pins 38 and a lower set of wire-wrap pins 40 that are spaced at one-quarter inch on center from each other. The pins 38, 40 are arranged in upper columns and lower columns that are vertically aligned with each other. The pins 38, 40 extend forward from a printed circuit board 60 through front module members 62 to ends 54 and rearward through rear module member 64 to wire-wrap terminal ends 56. The ends 56 are adapted for permanent termination with twisted wire pairs of the network elements. The forward front ends 64 are adapted to receive a female access plug 120 having four wire-wrap pin cavities 126. The printed circuit board 60 has a switch means 78 for operatively interconnecting a column 40 with a corresponding lower set of four pins 44. The female patch plug 120 includes a projecting switch actuating member 134 that serves to interrupt the normally closed condition of the switch means 78 when the female patch plug 120 is inserted over a selected column of pins 40, 44.
摘要翻译: 描述了一种低频电信数字网络接口接线板10,其能够终止并提供对产生1和3Mbps之间的低频信号的168路低频网络单元12和14的前向接入。 该面板具有一个具有二十一个相邻模块的外壳; 每个模块的宽度为一英寸,并且具有上部组的绕线销38和下部组的绕线销40,它们彼此间隔四分之一英寸。 销38,40布置在彼此垂直对齐的上列和下列中。 销38,40从印刷电路板60向前延伸通过前部模块构件62到端部54,并且向后延伸穿过后部模块构件64到线缠绕终端56.端部56适于用双绞线对 网络元素。 前部前端64适于接收具有四个线缠绕空腔126的阴接入插头120.印刷电路板60具有开关装置78,用于可操作地将柱40与相应的下部四个销44相互连接。 阴插座120包括突出开关致动构件134,用于当阴插片120插入选定的销钉40,44时,用于中断开关装置78的常闭状态。
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公开(公告)号:US5339379A
公开(公告)日:1994-08-16
申请号:US79054
申请日:1993-06-18
CPC分类号: G02B6/4455 , G02B6/4452 , G02B6/4453
摘要: A telecommunication fiber optic distribution apparatus 10 is illustrated in the drawings and includes a plurality of vertically spaced tray housings or shelves 18 that are mounted between vertical frame columns 16. Each of the tray housings slidably supports a plurality of optical fiber trays 20 that are movable linearly outward from a storage retracted position within the housing to an extended service position. Each of the trays has one or more cable carriers 60 that support and protect the optical fibers from being bent in an arc having a radius of curvature less than a predetermined value. Each of the trays 20 includes reels for storing extra lengths of the optical fibers. Releasable guides 46 are mounted along the outside of the housing for guiding fiber optic cable in a vertical direction to the desired shelves. Additionally, individual cable guides 44 are positioned adjacent the rear corners of the housing for additionally guiding the individual cables into and out of the carriers 60.
摘要翻译: 在附图中示出了电信光纤分配设备10,并且包括安装在垂直框架列16之间的多个垂直间隔开的托盘壳体或搁架18.每个托盘壳体可滑动地支撑多个可移动的光纤托盘20 从壳体内的存储缩回位置线性地向外延伸到延伸的维修位置。 每个托盘具有一个或多个电缆支架60,其支撑和保护光纤不会弯曲成具有小于预定值的曲率半径的弧。 每个托盘20包括用于存储额外长度的光纤的卷轴。 沿着壳体的外侧安装可拆卸的导向件46,以便在垂直于所需架子的方向上引导光纤电缆。 此外,各个电缆引导件44邻近壳体的后角定位,用于将各个电缆额外引导进入和离开载体60。
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公开(公告)号:US5115484A
公开(公告)日:1992-05-19
申请号:US634660
申请日:1990-12-27
申请人: Paul D. Johnson
发明人: Paul D. Johnson
CPC分类号: G02B6/4248 , G02B6/3816 , G02B6/3825 , G02B6/3887 , G02B6/3894
摘要: A device for connecting standard plastic covered fiber optic cable and armored fiber optic cable to a housing for electrical or electronic equipment. The device consist of a portion of the housing having a passage between an exterior surface of the housing and a interior surface of the housing. At the interior end of the passage is an aperture sized to receive a standard plastic covered fiber optic cable. The passage is tapered such that the interior end has a smaller diameter than the exterior end and the passage is threaded. A bushing is received in the passage. The bushing has a passage through its center through which the fiber optic cable passes. One end of the bushing is threaded and has an aperture in the center thereof sized for receiving a standard plastic covered fiber optic cable. The threaded end of the bushing also includes a longitudinal slot. As the bushing is screwed into the housing passage the slot compresses causing the aperture at the end of the threaded portion of the bushing to clamp around the fiber optic cable. The clamping action physically connects the fiber optic cable to the electrical equipment housing.
摘要翻译: 用于将标准塑料包覆光纤电缆和铠装光纤电缆连接到电气或电子设备外壳的设备。 该装置由壳体的一部分组成,该壳体的一部分在壳体的外表面和壳体的内表面之间具有通道。 在通道的内部端部是一个尺寸适于接收标准塑料覆盖光纤电缆的孔径。 通道是锥形的,使得内端具有比外端更小的直径,并且通道是螺纹的。 在通道中接纳套管。 衬套具有穿过其中心的通道,光缆穿过该中心。 衬套的一端是螺纹的,并且在其中心具有一个孔径,用于容纳标准的塑料覆盖的光纤电缆。 衬套的螺纹端还包括纵向槽。 当衬套旋入壳体通道时,狭槽压缩,使得衬套的螺纹部分的端部处的孔围绕光纤电缆夹紧。 夹紧动作将光纤电缆物理连接到电气设备外壳。
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公开(公告)号:US4924922A
公开(公告)日:1990-05-15
申请号:US258773
申请日:1988-10-17
申请人: Paul D. Johnson
发明人: Paul D. Johnson
CPC分类号: A47J31/02 , A47J31/061 , A47J31/50 , A47J41/0005
摘要: A heat insulated coffee carafe for placement at the brewed coffee outlet of a coffee maker is provided with a securely fitting lid through which the coffee passes directly into the carafe without removal of the lid. When the carafe and its lid are placed in the coffee maker, mutual pressure between the lid and the coffee maker causes seals in the lid to open and permits the coffee to enter the carafe without removing the lid and with a minimal loss of heat and coffee aroma. Removal of the carafe and lid from the coffee maker automatically closes the seals to retain the heat and aroma in the carafe for long periods of use. In another embodiment a positive drip-stop seal in the coffee maker is closed automatically when the carafe is removed, whereby dripping from the coffee maker is prevented. In a further embodiment, a drip-stop seal in the coffee maker and a seal in the lid are both opened when the carafe is installed in the coffee maker. The flow capacity of the drip-stop seal is less than that of the seal in the lid, whereby flow control of the coffee is provided. Special provisions permit an unblocked exhaust flow of air while liquid is being admitted to the carafe.
摘要翻译: 用于放置在咖啡机的咖啡出口处的隔热咖啡瓶设置有牢固配合的盖子,咖啡通过该盖子直接进入到瓶中而不移除盖子。 当咖啡壶及其盖子放置在咖啡机中时,盖子和咖啡壶之间的相互压力使得盖子中的密封件打开,并允许咖啡进入玻璃瓶而不需要移除盖子并且以最少的热量和咖啡的损失 香气。 从咖啡壶中取出瓶盖和盖子可自动关闭密封件,以保持长时间使用的保鲜液中的热量和香气。 在另一个实施例中,当咖啡壶被移除时,咖啡壶中的积极的滴落停止密封被自动关闭,从而防止从咖啡壶滴下。 在进一步的实施例中,当咖啡壶安装在咖啡机中时,咖啡壶中的滴落密封件和盖子中的密封都打开。 滴水密封件的流量小于盖子中的密封件的流动能力,从而提供咖啡的流量控制。 特殊规定允许在液体进入玻璃瓶时排出空气而排出。
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