公开(公告)号：US20070178023A1

公开(公告)日：2007-08-02

申请号：US11603950

申请日：2006-11-22

申请人： A. Russo ,  Phil Bergman ,  Matthew Stebulis ,  James Hope ,  Timothy Johnson ,  Howard Schreyer

发明人： A. Russo ,  Phil Bergman ,  Matthew Stebulis ,  James Hope ,  Timothy Johnson ,  Howard Schreyer

IPC分类号： B01J19/00

CPC分类号： C12P7/40 ,  B01J19/0093 ,  B01J2219/00038 ,  B01L3/5027 ,  C12M23/16 ,  C12M23/58 ,  C12M41/32 ,  C12M41/44 ,  C12P7/6463 ,  C12P13/04 ,  C12P19/34 ,  C12P33/00

摘要： Methods for forming chemical and/or biological products in reactors, and/or analyzing chemical and/or biological interactions in reactors are provided. The methods relate, more specifically, to forming such products and/or carrying out such analyses in small volume reactors with control over overall fluid volume in the reactors. The methods can be used to mimic processes in large scale reactors and/or to obtain reaction or interaction information relevant to large scale reactors (e.g., to adjust/optimize large-scale reactor processes). Advantageously, the methods can allow parameters of small scale reactors to be correlated with those of large scale reactors, where desired.

摘要翻译： 提供了在反应器中形成化学和/或生物产物和/或分析反应器中的化学和/或生物相互作用的方法。 所述方法更具体地涉及在具有对反应器中的总流体体积的控制的小体积反应器中形成这种产物和/或进行这种分析。 该方法可用于模拟大规模反应器中的工艺和/或获得与大规模反应器相关的反应或相互作用信息（例如，调整/优化大规模反应器工艺）。 有利地，如果需要，这些方法可以允许小规模反应器的参数与大规模反应器的参数相关。

公开(公告)号：US20070036690A1

公开(公告)日：2007-02-15

申请号：US11146922

申请日：2005-06-07

申请人： Scott Miller ,  A. Russo ,  Sean LeBlanc ,  Timothy Johnson

发明人： Scott Miller ,  A. Russo ,  Sean LeBlanc ,  Timothy Johnson

IPC分类号： B01J19/00 ,  B01L3/00

CPC分类号： B01J19/0093 ,  B01J2219/00837 ,  B01J2219/00862 ,  B01J2219/00869 ,  B01J2219/00907 ,  B01J2219/00952 ,  B01J2219/00963 ,  B01J2219/0097 ,  B01L3/5025 ,  B01L3/502715 ,  B01L3/502746 ,  B01L2200/027 ,  B01L2200/0668 ,  B01L2200/0684 ,  B01L2300/0816 ,  B01L2300/0825 ,  B01L2300/0877 ,  B01L2300/0887 ,  B01L2300/10 ,  B01L2400/0457 ,  B01L2400/0688 ,  B01L2400/086

摘要： The present invention generally relates to chemical, biological, and/or biochemical reactor microreactors and other reaction systems such as microreactor systems, as well as systems and methods for constructing and using such devices. In one aspect, a reactor on a chip has a container in fluid communication with a channel, and the channel is in fluid communication with a port for connecting the container to a source of fluid to be introduced into the container. The container can be very small, for example, with a volume of less than about 2 milliliters, and the fluid channel can have a channel volume of less than 1.5 percent of the container volume. According to another aspect, the combined volume of the port volume and the channel volume can be less than about 10 percent of the container volume. Such a configuration may increase the percentage of added fluid that reaches the container. In fed-batch operations, species may be added and removed via the same channel so that a gas headspace can be maintained within the reactor.

摘要翻译： 本发明一般涉及化学，生物和/或生化反应器微反应器和其它反应系统，例如微反应器系统，以及用于构建和使用这些装置的系统和方法。 在一个方面，芯片上的反应器具有与通道流体连通的容器，并且通道与用于将容器连接到待引入容器的流体源的端口流体连通。 容器可以非常小，例如，体积小于约2毫升，并且流体通道可以具有小于容器体积的1.5％的通道体积。 根据另一方面，端口容积和通道容积的组合体积可以小于容器体积的约10％。 这种构造可以增加到达容器的添加流体的百分比。 在补料分批操作中，可以通过相同的通道添加和除去物质，使得可以在反应器内保持气体顶部空间。

公开(公告)号：US20220097354A1

公开(公告)日：2022-03-31

申请号：US17514697

申请日：2021-10-29

申请人： Thomas S. Miller ,  Timothy Johnson

发明人： Thomas S. Miller ,  Timothy Johnson

IPC分类号： B32B27/12 ,  B32B7/12 ,  B32B5/02

摘要： A composite board with a multilayer laminated facer is presented having a nonwoven, a first polymer layer, and a second polymer layer. The laminate may be printed on the nonwoven, on the upper surface of the first polymer layer or inverted printed on the backside of an applied film. A number of configurations for the polymer layers are disclosed. The laminate may include exposed fibers on the lower surface or the nonwoven may be saturated. A removable peel-ply may be included. By controlling the placement and thickness of the polymer layers it is possible to tailor additive in the polymers such as colorants, opacifiers, UV stabilizers, and fire retardants to improve quality and reduce costs. In an alternate embodiment of the present invention, a first polymer layer is applied to the topside of the nonwoven and the second polymer is laminated to the first polymer layer as a preformed film. The laminated facer is thermally or adhesively bonded to the composite board.

公开(公告)号：US20200236969A1

公开(公告)日：2020-07-30

申请号：US16756675

申请日：2018-10-16

申请人： Timothy Johnson ,  Jessica Danzeisen ,  Bonnie Weber ,  REGENTS OF THE UNIVERSITY OF MINNESOTA

发明人： Timothy Johnson ,  Jessica Danzeisen ,  Bonnie Weber

IPC分类号： A23K10/18 ,  A23K50/75 ,  A61K35/742 ,  A61K35/747

摘要： Compositions including a bacterial species or a combination of bacterial species and methods of using those compositions are described. In some embodiments, use of the compositions prevents disease and/or promotes growth in an animal. In some embodiments, the animal is a turkey. In some embodiments, the composition is antibiotic-free.

公开(公告)号：US20180022074A1

公开(公告)日：2018-01-25

申请号：US14185655

申请日：2014-02-20

申请人： Thomas Miller ,  Timothy Johnson

发明人： Thomas Miller ,  Timothy Johnson

IPC分类号： B32B27/12 ,  B32B7/12 ,  B32B5/02

CPC分类号： B32B27/12 ,  B32B5/022 ,  B32B7/12 ,  B32B2607/00

摘要： A composite board with a multilayer laminated facer is presented having a nonwoven, a first polymer layer, and a second polymer layer. The laminate may be printed on the nonwoven, on the upper surface of the first polymer layer or inverted printed on the backside of an applied film. A number of configurations for the polymer layers are disclosed. The laminate may include exposed fibers on the lower surface or the nonwoven may be saturated. A removable peel-ply may be included. By controlling the placement and thickness of the polymer layers it is possible to tailor additive in the polymers such as colorants, opacifiers, UV stabilizers, and fire retardants to improve quality and reduce costs. In an alternate embodiment of the present invention, a first polymer layer is applied to the topside of the nonwoven and the second polymer is laminated to the first polymer layer as a preformed film. The laminated facer is thermally or adhesively bonded to the composite board.

公开(公告)号：US08693466B2

公开(公告)日：2014-04-08

申请号：US12420715

申请日：2009-04-08

申请人： Timothy Johnson

发明人： Timothy Johnson

IPC分类号： H04L12/66 ,  H04W40/00

CPC分类号： H04L65/102 ,  H04M3/42246 ,  H04M3/42263 ,  H04M3/543 ,  H04M7/1205 ,  H04M2203/1091 ,  H04M2250/06

摘要： Methods and apparatus for unified communication across circuit-switched and packet-switched network domains. In one embodiment, voice or data available in one domain (e.g., circuit-switched such as a PSTN) can be seamlessly forwarded onto another domain (e.g. packet-switched such as a WLAN). A bridge or intermediary device is used that is coupled to both the circuit-switched network and packet-switched network. This bridge device allows bidirectional operation and permits, for example, a user to receive a telephone call at a user's home network via a PSTN, and forward that telephone call or information related to that call over another network such as a local IP network (e.g. a WLAN) to the user, where the user can answer that call or otherwise receive information associated with the call on their primary user device (e.g., cellular phone).

摘要翻译： 电路交换和分组交换网络域统一通信的方法和装置。 在一个实施例中，可以将一个域（例如，诸如PSTN之类的电路交换机）中可用的语音或数据无缝地转发到另一个域（例如分组交换，例如WLAN）上。 使用耦合到电路交换网络和分组交换网络的桥接器或中间设备。 该桥接装置允许双向操作，并且例如允许用户经由PSTN在用户的家庭网络接收电话呼叫，并且通过诸如本地IP网络的其他网络（例如，本地IP网络）转发该电话呼叫或与该呼叫有关的信息。 WLAN），其中用户可以应答该呼叫或以其他方式接收与其主用户设备（例如，蜂窝电话）上的呼叫相关联的信息。

公开(公告)号：US08600080B2

公开(公告)日：2013-12-03

申请号：US12203883

申请日：2008-09-03

申请人： Wendell B. Sander ,  Jeffrey Terlizzi ,  Douglas M. Farrar ,  Timothy Johnson ,  Brian Sander ,  Brian J. Conner ,  Jesse L. Dorogusker

发明人： Wendell B. Sander ,  Jeffrey Terlizzi ,  Douglas M. Farrar ,  Timothy Johnson ,  Brian Sander ,  Brian J. Conner ,  Jesse L. Dorogusker

IPC分类号： H04R3/00

CPC分类号： H04M1/6058 ,  H04M1/05 ,  H04M1/72527 ,  H04M1/72558 ,  H04R1/1041 ,  H04R3/00 ,  H04R2499/11

摘要： Electronic devices and accessories such as headsets for electronic devices are provided. A microphone may be included in an accessory to capture sound for an associated electronic device. Buttons and other user interfaces may be included in the accessories. An accessory may have an audio plug that connects to a mating audio jack in an electronic device, thereby establishing a wired communications link between the accessory and the electronic device. The electronic device may include power supply circuitry for applying bias voltages to the accessory. The bias voltages may bias a microphone and may adjust settings in the accessory such as settings related to operating modes. User input information may be conveyed between the accessory and the electronic device using ultrasonic tone transmission. The electronic device may also gather input from the accessory using a voltage detector coupled to lines in the communications path.

摘要翻译： 提供电子设备和附件，例如电子设备的耳机。 附件中可以包括麦克风以捕获相关联的电子设备的声音。 按钮和其他用户界面可能包含在附件中。 附件可以具有连接到电子设备中的匹配音频插孔的音频插头，从而在附件和电子设备之间建立有线通信链路。 电子设备可以包括用于向附件施加偏置电压的电源电路。 偏置电压可能偏置麦克风，并可能会调整附件中的设置，例如与操作模式相关的设置。 用户输入信息可以使用超声波传输在配件和电子设备之间传送。 电子设备还可以使用耦合到通信路径中的线路的电压检测器从附件收集输入。

公开(公告)号：US20110150234A1

公开(公告)日：2011-06-23

申请号：US13038172

申请日：2011-03-01

申请人： Timothy Johnson ,  Achim Pantfoerder

发明人： Timothy Johnson ,  Achim Pantfoerder

IPC分类号： H04R1/10

CPC分类号： H04R3/00 ,  H01R13/703 ,  H01R24/58 ,  H01R29/00 ,  H01R2201/16 ,  H04M1/6058 ,  H04M1/72527 ,  H04R1/1041 ,  H04R29/00

摘要： A single prong, multiple signal conducting plug and plug detection circuitry is provided. The plug may be electrically coupled to a stereo headset including a microphone. The plug may include four signal conducting regions arranged in a predetermined order along the length of the prong. Detection circuitry may be operative to determine whether a microphone type of plug (e.g., a four region plug including a microphone region and two audio regions, or a three region plug including microphone region and only one audio region) or a non-microphone type of plug (e.g., stereo plug) is inserted into the jack of an electronic device (e.g., mobile phone). Detection circuitry may also detect user activated functions performed in response to user activation of one or more switches included with the headset. For example, the headset may include a single switch for performing a function with respect to a microphone (e.g., end-call function).

摘要翻译： 提供单个插脚，多信号导通插头和插头检测电路。 插头可以电耦合到包括麦克风的立体声耳机。 插头可以包括沿着插脚的长度以预定顺序布置的四个信号导通区域。 检测电路可以用于确定麦克风类型的插头（例如，包括麦克风区域和两个音频区域的四区域插头，或包括麦克风区域和仅一个音频区域的三区域插头）或非麦克风类型的 插头（例如，立体声插头）插入到电子设备（例如，移动电话）的插孔中。 检测电路还可以检测响应于耳机中包括的一个或多个开关的用户激活而执行的用户激活的功能。 例如，耳机可以包括用于执行关于麦克风的功能的单个开关（例如，终端呼叫功能）。

公开(公告)号：US07833265B2

公开(公告)日：2010-11-16

申请号：US12048053

申请日：2008-03-13

申请人： Timothy Johnson ,  George W. Keilman

发明人： Timothy Johnson ,  George W. Keilman

IPC分类号： A61F2/06

CPC分类号： A61F2/86 ,  A61F2/848 ,  A61F2/954 ,  A61F2/966 ,  A61F2002/821 ,  A61F2002/9665 ,  A61F2220/0008 ,  A61F2230/0008

摘要： As described herein vascular anchoring systems are used to position an implant in a vascular area such as a bifurcated vasculature with relatively high fluid flow, for instance, in an area of a pulmonary artery with associated left and right pulmonary arteries. Implementations include an anchoring trunk member having a first anchoring trunk section and a second anchoring trunk section. Further implementations include a first anchoring branch member extending from the anchoring trunk member. Still further implementations include a second anchoring branch member extending from the anchoring trunk member.

摘要翻译： 如本文所描述的，血管锚定系统用于将植入物定位在诸如具有相对高的流体流动的分叉血管的血管区域中，例如在具有相关联的左肺动脉和右肺动脉的肺动脉的区域中。 实施方案包括具有第一锚固干线部分和第二锚固干线部分的锚固干线部件。 另外的实施方案包括从锚固树干构件延伸的第一锚定分支构件。 另外的实施方式包括从锚固树干构件延伸的第二锚定分支构件。

公开(公告)号：US20100260173A1

公开(公告)日：2010-10-14

申请号：US12420715

申请日：2009-04-08

申请人： Timothy Johnson

发明人： Timothy Johnson

IPC分类号： H04L12/66

CPC分类号： H04L65/102 ,  H04M3/42246 ,  H04M3/42263 ,  H04M3/543 ,  H04M7/1205 ,  H04M2203/1091 ,  H04M2250/06

摘要： Methods and apparatus for unified communication across circuit-switched and packet-switched network domains. In one embodiment, voice or data available in one domain (e.g., circuit-switched such as a PSTN) can be seamlessly forwarded onto another domain (e.g. packet-switched such as a WLAN). A bridge or intermediary device is used that is coupled to both the circuit-switched network and packet-switched network. This bridge device allows bidirectional operation and permits, for example, a user to receive a telephone call at a user's home network via a PSTN, and forward that telephone call or information related to that call over another network such as a local IP network (e.g. a WLAN) to the user, where the user can answer that call or otherwise receive information associated with the call on their primary user device (e.g., cellular phone).

摘要翻译： 电路交换和分组交换网络域统一通信的方法和装置。 在一个实施例中，可以将一个域（例如，诸如PSTN之类的电路交换机）中可用的语音或数据无缝地转发到另一个域（例如分组交换，例如WLAN）上。 使用耦合到电路交换网络和分组交换网络的桥接器或中间设备。 该桥接装置允许双向操作，并且例如允许用户经由PSTN在用户的家庭网络接收电话呼叫，并且通过诸如本地IP网络的其他网络（例如，本地IP网络）转发该电话呼叫或与该呼叫有关的信息。 WLAN），其中用户可以应答该呼叫或以其他方式接收与其主用户设备（例如，蜂窝电话）上的呼叫相关联的信息。