CONFORMABLE BARRIER SHEET, METHODS, AND DEVICE
    1.
    发明申请
    CONFORMABLE BARRIER SHEET, METHODS, AND DEVICE 审中-公开
    一致的障碍物,方法和装置

    公开(公告)号:US20120237763A1

    公开(公告)日:2012-09-20

    申请号:US13512764

    申请日:2010-11-29

    摘要: A conformable barrier sheet comprising a polymeric film having a tensile elongation at least 2 fold greater than a polyethylene terephthalate film of equal dimensions and under an equal load; a planarization layer; and a plasma-deposited amorphous glass layer comprising silicon, carbon, and hydrogen; wherein the planarization layer is disposed on the polymeric film, the amorphous glass layer is deposited on the planarization layer, and wherein the barrier sheet is sufficiently conformable that after undergoing a tensile elongation within the range of more than 2% to 20%, the barrier sheet has a moisture vapor transmission rate essentially unchanged compared with prior to being elongated, a method of making the conformable barrier sheet, a transdermal device comprising the conformable barrier sheet, a method of delivering a drug to a mammal using the device, and a method of protecting an article using the conformable barrier sheet are provided.

    摘要翻译: 一种适合的阻挡片,其包含聚合物膜,其拉伸伸长率比相同尺寸和相等载荷下的聚对苯二甲酸乙二醇酯膜大至少2倍; 平坦化层; 以及包含硅,碳和氢的等离子体沉积的非晶玻璃层; 其中所述平坦化层设置在所述聚合物膜上,所述非晶玻璃层沉积在所述平坦化层上,并且其中所述阻挡片具有足够的适应性,使得在经历超过2%至20%的范围内的拉伸伸长率时, 片材具有与延伸之前基本不变的水蒸气透过率,制造适形阻隔片的方法,包含适形阻挡片的透皮装置,使用该装置将药物递送至哺乳动物的方法,以及方法 提供了使用适形阻挡片保护制品的方法。