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公开(公告)号：US10052045B2
公开(公告)日：2018-08-21
申请号：US14441184
申请日：2012-12-21
Applicant: Colgate-Palmolive Company
Inventor： Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid
CPC classification number: A61B5/08 , A61B5/082 , A61B10/00 , A61B2010/0087 , A61K8/33 , A61K8/35 , A61K8/55 , A61Q11/00 , G01N33/497 , G01N2033/4975 , Y10T436/182
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from onion and garlic. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a first sample of exhaled breath from the cleaned oral cavity to provide a first test result representing a first amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a second sample of exhaled breath from the oral cavity to provide a second test result representing a second amount of the at least one oral malodor component detected in the exhaled breath.
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公开(公告)号：US20160008254A1
公开(公告)日：2016-01-14
申请号：US14652780
申请日：2012-12-19
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： Zhigang Hao , Ying Yang , Zhiqiang Liu , Xu Guofeng , Paul Joseph Vincenti
CPC classification number: A61K8/58 , A61K8/27 , A61K8/55 , A61K8/676 , A61K33/30 , A61K2800/58 , A61Q11/00
Abstract: Provided herein is an oral care composition comprising an orally-acceptable aqueous vehicle and an antimicrobial ingredient, wherein the antimicrobial ingredient comprises a zinc ascorbylphosphate and methods for treating or preventing a disease or disorder of the oral cavity using the oral care compositions disclosed herein.
Abstract translation: 本文提供了包含口服可接受的水性载体和抗微生物成分的口腔护理组合物，其中所述抗微生物成分包含抗坏血酸磷酸锌和使用本文公开的口腔护理组合物治疗或预防口腔疾病或病症的方法。
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公开(公告)号：US20150265183A1
公开(公告)日：2015-09-24
申请号：US14441184
申请日：2012-12-21
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid
IPC: A61B5/08 , A61B10/00 , G01N33/497 , A61Q11/00 , A61K8/55
CPC classification number: A61B5/08 , A61B5/082 , A61B10/00 , A61B2010/0087 , A61K8/33 , A61K8/35 , A61K8/55 , A61Q11/00 , G01N33/497 , G01N2033/4975 , Y10T436/182
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from onion and garlic. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a first sample of exhaled breath from the cleaned oral cavity to provide a first test result representing a first amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a second sample of exhaled breath from the oral cavity to provide a second test result representing a second amount of the at least one oral malodor component detected in the exhaled breath.
Abstract translation: 本发明涉及一种口服恶臭的检测方法，特别是洋葱和大蒜口服恶臭。 本文描述了用于测试口腔护理组合物降低口腔恶臭的功效的方法，该方法包括以下步骤：a）用口腔护理组合物清洁至少一部分口腔; b）从清洁的口腔测试呼出呼吸的第一样本，以提供表示在呼出气中检测到的第一量的至少一种口腔恶臭成分的第一测试结果; c）将口腔暴露于包含或能够形成至少一种口腔恶臭成分的口腔恶臭物质; 以及d）从所述口腔测试第二呼出呼气样品，以提供第二测试结果，所述第二测试结果代表在所述呼出气体中检测到的所述至少一种口腔恶臭成分的第二量。
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Patent Agency Ranking
公开(公告)号：US09823236B2
公开(公告)日：2017-11-21
申请号：US14441962
申请日：2012-12-21
Applicant: Colgate-Palmolive Company
Inventor： Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid , Ariel Haskel
CPC classification number: G01N33/497 , A61K8/24 , A61K8/33 , A61K8/35 , A61K8/4913 , A61K8/4973 , A61K2800/591 , A61Q11/00
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from coffee. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a sample of exhaled breath from the cleaned oral cavity to provide a test result representing a amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a sample of exhaled breath from the oral cavity to provide a test result representing an amount of the at least one oral malodor component detected in the exhaled breath.
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公开(公告)号：US09757320B2
公开(公告)日：2017-09-12
申请号：US14652780
申请日：2012-12-19
Applicant: Colgate-Palmolive Company
Inventor： Zhigang Hao , Ying Yang , Zhiqiang Liu , Xu Guofeng , Paul Joseph Vincenti
CPC classification number: A61K8/58 , A61K8/27 , A61K8/55 , A61K8/676 , A61K33/30 , A61K2800/58 , A61Q11/00
Abstract: Provided herein is an oral care composition comprising an orally-acceptable aqueous vehicle and an antimicrobial ingredient, wherein the antimicrobial ingredient comprises a zinc ascorbylphosphate and methods for treating or preventing a disease or disorder of the oral cavity using the oral care compositions disclosed herein.
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公开(公告)号：US09993414B2
公开(公告)日：2018-06-12
申请号：US14652785
申请日：2012-12-17
Applicant: Colgate-Palmolive Company
Inventor： Zhigang Hao , Ying Yang , Zhiqiang Liu , Katherine Hu , Guofeng Xu , Paul Joseph Vincenti
CPC classification number: A61K8/60 , A61K2800/92 , A61Q11/00
Abstract: The present invention relates to oral care compositions and methods of inhibiting microbial biofilm formation and/or degrading a microbial biofilm. Disclosed herein are oral care compositions comprising an Amadori compound having a glucose moiety and an amino acid moiety. The Amadori compound has use for inhibiting oral microbial biofilm formation and/or degrading an oral microbial biofilm in the oral cavity of a mammalian subject.
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公开(公告)号：US20150328120A1
公开(公告)日：2015-11-19
申请号：US14652785
申请日：2012-12-17
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： Zhigang Hao , Ying Yang , Zhiqiang Liu , Katherine Hu , Guofeng Xu , Paul Joseph Vincenti
CPC classification number: A61K8/60 , A61K2800/92 , A61Q11/00
Abstract: The present invention relates to oral care compositions and methods of inhibiting microbial biofilm formation and/or degrading a microbial biofilm. Disclosed herein are oral care compositions comprising an Amadori compound having a glucose moiety and an amino acid moiety. The Amadori compound has use for inhibiting oral microbial biofilm formation and/or degrading an oral microbial biofilm in the oral cavity of a mammalian subject.
Abstract translation: 本发明涉及口腔护理组合物和抑制微生物生物膜形成和/或降解微生物生物膜的方法。 本文公开了包含具有葡萄糖部分和氨基酸部分的阿马多里化合物的口腔护理组合物。 阿马多利化合物可用于抑制口腔微生物生物膜形成和/或降解哺乳动物受试者口腔中的口腔微生物生物膜。
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公开(公告)号：US20150293075A1
公开(公告)日：2015-10-15
申请号：US14441962
申请日：2012-12-21
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid , Ariel Haskel
IPC: G01N33/497 , A61K8/33 , A61K8/35 , A61Q11/00 , A61K8/24
CPC classification number: G01N33/497 , A61K8/24 , A61K8/33 , A61K8/35 , A61K8/4913 , A61K8/4973 , A61K2800/591 , A61Q11/00
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from coffee. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a sample of exhaled breath from the cleaned oral cavity to provide a test result representing a amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a sample of exhaled breath from the oral cavity to provide a test result representing an amount of the at least one oral malodor component detected in the exhaled breath.
Abstract translation: 本发明涉及一种用于测试口腔恶臭，特别是咖啡口服恶臭的方法。 本文描述了用于测试口腔护理组合物降低口腔恶臭的功效的方法，该方法包括以下步骤：a）用口腔护理组合物清洁至少一部分口腔; b）从清洁的口腔测试呼出的呼吸样品，以提供表示在呼出气中检测到的至少一种口腔恶臭成分的量的测试结果; c）将口腔暴露于包含或能够形成至少一种口腔恶臭成分的口腔恶臭物质; 以及d）从口腔测试呼出的呼吸样品，以提供表示在呼出气中检测到的至少一种口腔恶臭成分的量的测试结果。
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