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公开(公告)号：US20190194692A1
公开(公告)日：2019-06-27
申请号：US15541665
申请日：2016-01-06
Applicant: DSM IP ASSETS B.V. , RIJKSUNIVERSITEIT GRONINGEN
Inventor： Bernard MEIJRINK , René VERWAAL , Bianca Elisabeth Maria GIELESEN , Johannes Andries ROUBOS , Carsten POHL , Arnold Jacob Mattieu DRIESSEN , Roelof Ary Lans BOVENBERG , Yvonne Irene NYGÅRD
CPC classification number: C12N15/902 , C12N9/22 , C12N15/11 , C12N2310/20 , C12N2800/80
Abstract: The present invention relates to the field of molecular biology and cell biology. More specifically, the present invention relates to a CRISPR-CAS system for a filamentous fungal host cell.
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2.发明申请公开(公告)号：US20190177748A1
公开(公告)日：2019-06-13
申请号：US16283208
申请日：2019-02-22
Applicant: DSM IP ASSETS B.V.
Inventor： Paul KLAASSEN , Gijsberdina Pieternella VAN SUYLEKOM , Bianca Elisabeth Maria GIELESEN , Nicolette Jasmijn BROERS , Beate WIEDEMANN , Wilhelmus Theodorus Antonius Maria DE LAAT
Abstract: The present invention relates to a process for the production of one or more fermentation product from a sugar composition, comprising the following steps: a) fermentation of the sugar composition in the presence of a yeast belonging to the genera Saccharomyces, Kluyveromyces, Candida, Pichia, Schizosaccharomyces, Hansenula, Kloeckera, Schwanniomyces or Yarrowia: and b) recovery of the fermentation product, wherein the yeast comprises the genes araA, arae and araD and the sugar composition comprises glucose, galactose and arabinose.
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公开(公告)号：US20150291983A1
公开(公告)日：2015-10-15
申请号：US14750084
申请日：2015-06-25
Applicant: DSM IP ASSETS B.V.
Inventor： Paul KLAASSEN , Bianca Elisabeth Maria GIELESEN , Gijsberdina Pieternella VAN SUYLEKOM , Wilbert Herman Marie HEIJNE
IPC: C12P7/10 , C12N9/04 , C12N9/12 , C12N9/90 , C12P7/16 , C12P7/56 , C12P7/42 , C12P7/40 , C12P7/54 , C12P7/46 , C12P7/48 , C12P7/44 , C12P13/00 , C12P13/08 , C12P13/12 , C12P13/22 , C12P13/20 , C12P7/18 , C12P7/20 , C12P5/02 , C12P35/00 , C12P17/10 , C12N9/50 , C12N9/42 , C12N9/26 , C12N9/24 , C12N9/38 , C12N9/16 , C12N9/88 , C12N9/02 , C12N9/10 , C12N9/92
CPC classification number: C12P7/10 , C07K14/395 , C12N1/36 , C12N9/0004 , C12N9/0006 , C12N9/10 , C12N9/1205 , C12N9/16 , C12N9/2405 , C12N9/2411 , C12N9/2437 , C12N9/2468 , C12N9/248 , C12N9/50 , C12N9/88 , C12N9/90 , C12N9/92 , C12P5/026 , C12P7/16 , C12P7/18 , C12P7/20 , C12P7/40 , C12P7/42 , C12P7/44 , C12P7/46 , C12P7/48 , C12P7/54 , C12P7/56 , C12P13/005 , C12P13/08 , C12P13/12 , C12P13/20 , C12P13/227 , C12P17/10 , C12P35/00 , C12Y101/01 , C12Y207/01016 , C12Y501/03004 , C12Y503/01004 , Y02E50/16 , Y02E50/17 , Y02E50/343
Abstract: The present invention relates to a cell suitable for production of one or more fermentation product from a sugar composition comprising glucose, galactose, arabinose and xylose, wherein the cell comprises two to fifteen copies of one or more xylose isomerase gene or two to fifteen copies of one or more xylose reductase and xylitol dehydrogenase, and two to ten copies of araA, araB and araD, genes, wherein these genes are integrated into the cell genome.
Abstract translation: 本发明涉及适用于从包含葡萄糖，半乳糖，阿拉伯糖和木糖的糖组合物生产一种或多种发酵产物的细胞，其中所述细胞包含两至十五份一种或多种木糖异构酶基因或两至十五份 一种或多种木糖还原酶和木糖醇脱氢酶，以及两至十个拷贝的araA，araB和araD基因，其中这些基因整合到细胞基因组中。
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Patent Agency Ranking
公开(公告)号：US20200032252A1
公开(公告)日：2020-01-30
申请号：US16500717
申请日：2018-04-04
Applicant: DSM IP ASSETS B.V.
Abstract: The present invention relates to the field of molecular biology and cell biology. More specifically, the present invention relates to a self-guiding integration construct for a genome editing system.
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5.发明申请公开(公告)号：US20170121738A1
公开(公告)日：2017-05-04
申请号：US15407341
申请日：2017-01-17
Applicant: DSM IP ASSETS B.V.
Inventor： Paul KLAASSEN , Gijsberdina Pieternella VAN SUYLEKOM , Bianca Elisabeth Maria GIELESEN , Nicolette Jasmijn BROERS , Beate WIEDEMANN , Wilhelmus Theodorus Antonius Maria DE LAAT
CPC classification number: C12P7/10 , C12P7/46 , Y02E50/16 , Y02E50/17 , Y02E50/343
Abstract: The present invention relates to a process for the production of one or more fermentation product from a sugar composition, comprising the following steps: a) fermentation of the sugar composition in the presence of a yeast belonging to the genera Saccharomyces, Kluyveromyces, Candida, Pichia, Schizosaccharomyces, Hansenula, Kloeckera, Schwanniomyces or Yarrowia: and b) recovery of the fermentation product, wherein the yeast comprises the genes araA, araB and araD and the sugar composition comprises glucose, galactose and arabinose.
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公开(公告)号：US20230287436A1
公开(公告)日：2023-09-14
申请号：US18187937
申请日：2023-03-22
Applicant: DSM IP ASSETS B.V. , MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventor： Eric Mosher YOUNG , Amar GHODASARA , René VERWAAL , Johannes Andries ROUBOS , Bianca Elisabeth Maria GIELESEN , Brenda VONK , Alec A.K. NIELSEN , Christopher Ashby VOIGT
CPC classification number: C12N15/66 , C12N9/22 , C12N2310/20
Abstract: The present invention relates to the field of molecular biology and cell biology. More specifically, the present invention relates to a guide-RNA expression system for a eukaryotic host cell.
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公开(公告)号：US20210198701A1
公开(公告)日：2021-07-01
申请号：US17199823
申请日：2021-03-12
Applicant: DSM IP ASSETS B.V.
Inventor： Paul KLAASSEN , Gijsberdina Pieternella VAN SUYLEKOM , Bianca Elisabeth Maria GIELESEN , Nicolette Jasmijn BROERS , Beate WIEDEMANN , Wilhelmus Theodorus Antonius Maria DE LAAT
Abstract: The present invention relates to a process for the production of one or more fermentation product from a sugar composition, comprising the following steps: a) fermentation of the sugar composition in the presence of a yeast belonging to the genera Saccharomyces, Kluyveromyces, Candida, Pichia, Schizosaccharomyces, Hansenula, Kloeckera, Schwanniomyces or Yarrowia: and b) recovery of the fermentation product, wherein the yeast comprises the genes araA, araB and araD and the sugar composition comprises glucose, galactose and arabinose.
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公开(公告)号：US20200165637A1
公开(公告)日：2020-05-28
申请号：US16780389
申请日：2020-02-03
Applicant: DSM IP ASSETS B.V.
Inventor： Bernard MEIJRINK , René VERWAAL , Bianca Elisabeth Maria GIELESEN , Johannes Andries ROUBOS
Abstract: The present invention relates to the field of molecular biology and cell biology. More specifically, the present invention relates to a CRISPR-CAS system for a lipolytic yeast host cell.
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