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公开(公告)号：US20080051338A1
公开(公告)日：2008-02-28
申请号：US11777133
申请日：2007-07-12
申请人： George Komatsoulis , Craig Rosen , Steven Ruben , Roxanne Duan , Paul Moore , Yanggu Shi , David LaFleur , Ying-Fei Wei , Jian Ni , Kimberly Florence , Paul Young , Laurie Brewer , Daniel Soppet , Gregory Endress , Reinhard Ebner , Henrik Olsen , Michael Mucenski
发明人： George Komatsoulis , Craig Rosen , Steven Ruben , Roxanne Duan , Paul Moore , Yanggu Shi , David LaFleur , Ying-Fei Wei , Jian Ni , Kimberly Florence , Paul Young , Laurie Brewer , Daniel Soppet , Gregory Endress , Reinhard Ebner , Henrik Olsen , Michael Mucenski
IPC分类号： A61K31/70 , A61K38/00 , C07K14/00 , C07K16/18 , C12N15/00 , C12N15/11 , C12N15/87 , C12N5/06 , C12P21/04 , C12Q1/68 , G01N33/53
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20070020724A1
公开(公告)日：2007-01-25
申请号：US10886642
申请日：2004-07-09
申请人： Steven Ruben , Jian Ni , Craig Rosen , Ying-Fei Wei , Paul Young , Kimberly Florence , Daniel Soppet , Laurie Brewer , Gregory Endress , Kenneth Carter , Michael Mucenski , Reinhard Ebner , David LaFleur , Henrik Olsen , Yanggu Shi , Paul Moore , George Komatsoulis
发明人： Steven Ruben , Jian Ni , Craig Rosen , Ying-Fei Wei , Paul Young , Kimberly Florence , Daniel Soppet , Laurie Brewer , Gregory Endress , Kenneth Carter , Michael Mucenski , Reinhard Ebner , David LaFleur , Henrik Olsen , Yanggu Shi , Paul Moore , George Komatsoulis
CPC分类号： C07K14/47
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20060079670A1
公开(公告)日：2006-04-13
申请号：US11229769
申请日：2005-09-20
申请人： George Komatsoulis , Craig Rosen , Steven Ruben , Roxanne Duan , Paul Moore , Yanggu Shi , David LaFleur , Ying-Fei Wei , Jian Ni , Kimberly Florence , Paul Young , Laurie Brewer , Daniel Soppet , Gregory Endress , Reinhard Ebner , Henrik Olsen , Michael Mucenski
发明人： George Komatsoulis , Craig Rosen , Steven Ruben , Roxanne Duan , Paul Moore , Yanggu Shi , David LaFleur , Ying-Fei Wei , Jian Ni , Kimberly Florence , Paul Young , Laurie Brewer , Daniel Soppet , Gregory Endress , Reinhard Ebner , Henrik Olsen , Michael Mucenski
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20060036089A1
公开(公告)日：2006-02-16
申请号：US11240769
申请日：2005-10-03
申请人： Daniel Soppet , Paul Moore , Yanggu Shi , Steven Ruben , Craig Rosen , David LaFleur , Henrik Olsen , Reinhard Ebner , Kimberly Florence , Paul Young , George Komatsoulis , Jian Ni
发明人： Daniel Soppet , Paul Moore , Yanggu Shi , Steven Ruben , Craig Rosen , David LaFleur , Henrik Olsen , Reinhard Ebner , Kimberly Florence , Paul Young , George Komatsoulis , Jian Ni
IPC分类号： C07H21/04 , C12P21/06 , C07K14/705 , C07K14/47
摘要： The present invention relates to 33 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及33种新型人分泌蛋白和含有编码这种蛋白质的基因的编码区的分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20070014787A1
公开(公告)日：2007-01-18
申请号：US11375555
申请日：2006-03-15
申请人： Steven Ruben , George Komatsoulis , D. Duan , Craig Rosen , Paul Moore , Yanggu Shi , David LaFleur , Reinhard Ebner , Henrik Olsen , Laurie Brewer , Kimberly Florence , Paul Young , Michael Mucenski , Gregory Endress , Daniel Soppet
发明人： Steven Ruben , George Komatsoulis , D. Duan , Craig Rosen , Paul Moore , Yanggu Shi , David LaFleur , Reinhard Ebner , Henrik Olsen , Laurie Brewer , Kimberly Florence , Paul Young , Michael Mucenski , Gregory Endress , Daniel Soppet
IPC分类号： A61K39/395 , C12Q1/68 , C07H21/04 , C12P21/06 , C07K14/705 , C07K16/28
CPC分类号： C07K14/47 , A61K38/00 , C07K2319/30
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20050095612A1
公开(公告)日：2005-05-05
申请号：US10866831
申请日：2004-06-15
申请人： Steven Ruben , Paul Young , Laurie Brewer , Reinhard Ebner , Henrik Olsen , Kimberly Florence , Craig Rosen , Roxanne Duan , Paul Moore , Yanggu Shi , David LaFleur , Charles Florence , Daniel Soppet , Gregory Endress , Ping Feng , George Komatsoulis
发明人： Steven Ruben , Paul Young , Laurie Brewer , Reinhard Ebner , Henrik Olsen , Kimberly Florence , Craig Rosen , Roxanne Duan , Paul Moore , Yanggu Shi , David LaFleur , Charles Florence , Daniel Soppet , Gregory Endress , Ping Feng , George Komatsoulis
IPC分类号： G01N33/53 , A61K38/00 , A61P43/00 , C07K14/47 , C07K16/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/68 , G01N33/68 , C07H21/04 , C12N9/00
CPC分类号： C07K14/47 , A61K38/00 , G01N33/6893 , G01N2500/20
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的病症的诊断和治疗方法。
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公开(公告)号：US20050239099A1
公开(公告)日：2005-10-27
申请号：US10963903
申请日：2004-10-14
申请人： Steven Ruben , Jian Ni , Reinhard Ebner , Craig Rosen , Yanggu Shi , Charles Birse , Kimberly Florence , George Komatsoulis , David LaFleur , Paul Moore , Henrik Olsen , Paul Young
发明人： Steven Ruben , Jian Ni , Reinhard Ebner , Craig Rosen , Yanggu Shi , Charles Birse , Kimberly Florence , George Komatsoulis , David LaFleur , Paul Moore , Henrik Olsen , Paul Young
IPC分类号： G01N33/50 , A61K31/711 , A61K38/00 , A61K48/00 , A61P9/00 , A61P17/00 , A61P19/02 , A61P25/02 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/12 , A61P35/00 , A61P37/00 , A61P43/00 , C07H21/04 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N15/09 , C12P21/02 , C12Q1/00 , C12Q1/02 , C12Q1/68 , C12Q1/6883 , G01N33/15 , G01N33/53 , G01N33/566
CPC分类号： C07K14/47 , C12Q1/00 , C12Q1/6883
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20070172830A1
公开(公告)日：2007-07-26
申请号：US10849979
申请日：2004-05-21
申请人： Steven Ruben , Kimberly Florence , Jian Ni , Craig Rosen , Kenneth Carter , Paul Moore , Henrik Olsen , Yanggu Shi , Paul Young , Ying-Fei Wei , Laurie Brewer , Daniel Soppet , David LaFleur , Gregory Endress , Reinhard Ebner , Charles Birse
发明人： Steven Ruben , Kimberly Florence , Jian Ni , Craig Rosen , Kenneth Carter , Paul Moore , Henrik Olsen , Yanggu Shi , Paul Young , Ying-Fei Wei , Laurie Brewer , Daniel Soppet , David LaFleur , Gregory Endress , Reinhard Ebner , Charles Birse
CPC分类号： C07K14/47
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20060084082A1
公开(公告)日：2006-04-20
申请号：US11144947
申请日：2005-06-06
申请人： Steven Ruben , Craig Rosen , Daniel Soppet , Kenneth Carter , Daniel Bednarik , Gregory Endress , Guo-Liang Yu , Jian Ni , Ping Feng , Paul Young , John Greene , Ann Ferrie , D. Duan , Jing-Shan Hu , Kimberly Florence , Henrik Olsen , Carrie Fischer , Reinhard Ebner , Laurie Brewer , Paul Moore , Yanggu Shi , David LaFleur , Yi Li , ZhiZhen Zeng , Hla Kyaw
发明人： Steven Ruben , Craig Rosen , Daniel Soppet , Kenneth Carter , Daniel Bednarik , Gregory Endress , Guo-Liang Yu , Jian Ni , Ping Feng , Paul Young , John Greene , Ann Ferrie , D. Duan , Jing-Shan Hu , Kimberly Florence , Henrik Olsen , Carrie Fischer , Reinhard Ebner , Laurie Brewer , Paul Moore , Yanggu Shi , David LaFleur , Yi Li , ZhiZhen Zeng , Hla Kyaw
CPC分类号： C07K14/4748 , A61K38/00 , C07K14/47 , G01N33/566 , G01N2800/00
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
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公开(公告)号：US20060223077A1
公开(公告)日：2006-10-05
申请号：US11229770
申请日：2005-09-20
申请人： Jian Ni , Reinhard Ebner , David LaFleur , Paul Moore , Henrik Olsen , Craig Rosen , Steven Ruben , Daniel Soppet , Paul Young , Yanggu Shi , Kimberly Florence , Ying-Fei Wei , Charles Florence , Jing-Shan Hu , Yi Li , Hla Kyaw , Carrie Fischer , Ann Ferrie , Ping Fan , Ping Feng , Gregory Endress , Patrick Dillon , Kenneth Carter , Laurie Brewer , Guo-Liang Yu , Zhizhen Zeng , John Greene
发明人： Jian Ni , Reinhard Ebner , David LaFleur , Paul Moore , Henrik Olsen , Craig Rosen , Steven Ruben , Daniel Soppet , Paul Young , Yanggu Shi , Kimberly Florence , Ying-Fei Wei , Charles Florence , Jing-Shan Hu , Yi Li , Hla Kyaw , Carrie Fischer , Ann Ferrie , Ping Fan , Ping Feng , Gregory Endress , Patrick Dillon , Kenneth Carter , Laurie Brewer , Guo-Liang Yu , Zhizhen Zeng , John Greene
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
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