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公开(公告)号：US08968232B2
公开(公告)日：2015-03-03
申请号：US13018054
申请日：2011-01-31
申请人： Dean Kamen , Jason A. Demers , David E. Altobelli , Larry B. Gray , N. Christopher Perry , Brian Tracey , James D. Dale , Dirk A. van der Merwe , Kingston Owens
发明人： Dean Kamen , Jason A. Demers , David E. Altobelli , Larry B. Gray , N. Christopher Perry , Brian Tracey , James D. Dale , Dirk A. van der Merwe , Kingston Owens
IPC分类号： A61M37/00 , C02F1/44 , A61M1/00 , A61M1/10 , A61M1/36 , F04B43/06 , F04B43/073 , G01K1/08 , G01K1/16 , G01M3/18 , A61F7/12
CPC分类号： A61M1/106 , A61F7/12 , A61F2007/0069 , A61F2007/126 , A61M1/1006 , A61M1/1012 , A61M1/1037 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/3626 , A61M1/369 , A61M2205/12 , A61M2205/127 , A61M2205/27 , A61M2205/3334 , A61M2205/3368 , A61M2205/3606 , A61M2205/3653 , A61M2205/502 , F04B43/0054 , F04B43/06 , F04B43/0736 , G01K1/08 , G01K1/16 , G01M3/188
摘要： Embodiments of the present invention relate generally to heat-exchanger systems that can be used to heat or cool a fluid such as blood. Pod pumps that provide low shear and low turbulence may be used in such systems, particularly for systems that pump blood. A certain heat-exchanger system used to heat blood or other fluids may be used to provide whole-body hyperthermic treatments or regional hyperthermic chemotherapy treatments. A disposable unit may be used to separate the fluid path from the fluid control systems. The disposable unit typically includes a heat-exchanger component that is received by a corresponding heat exchanger in a base unit. Fluid pumped through the heat-exchanger component is heated by the heat exchanger.
摘要翻译： 本发明的实施例一般涉及可用于加热或冷却诸如血液的流体的热交换器系统。 可以在这种系统中使用提供低剪切和低湍流的杓式泵，特别是用于泵送血液的系统。 用于加热血液或其他液体的某种热交换器系统可用于提供全身热疗治疗或局部高热化疗治疗。 可以使用一次性单元来将流体路径与流体控制系统分离。 一次性单元通常包括由基本单元中的相应热交换器接收的热交换器部件。 泵送通过热交换器部件的流体被热交换器加热。
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公开(公告)号：US20110218600A1
公开(公告)日：2011-09-08
申请号：US13018054
申请日：2011-01-31
申请人： Dean Kamen , Jason A. Demers , David E. Altobelli , Larry B. Gray , N. Christopher Perry , Brian Tracey , James D. Dale , Dirk A. van der Merwe , Kingston Owens
发明人： Dean Kamen , Jason A. Demers , David E. Altobelli , Larry B. Gray , N. Christopher Perry , Brian Tracey , James D. Dale , Dirk A. van der Merwe , Kingston Owens
IPC分类号： A61F7/00
CPC分类号： A61M1/106 , A61F7/12 , A61F2007/0069 , A61F2007/126 , A61M1/1006 , A61M1/1012 , A61M1/1037 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/3626 , A61M1/369 , A61M2205/12 , A61M2205/127 , A61M2205/27 , A61M2205/3334 , A61M2205/3368 , A61M2205/3606 , A61M2205/3653 , A61M2205/502 , F04B43/0054 , F04B43/06 , F04B43/0736 , G01K1/08 , G01K1/16 , G01M3/188
摘要： Embodiments of the present invention relate generally to heat-exchanger systems that can be used to heat or cool a fluid such as blood. Pod pumps that provide low shear and low turbulence may be used in such systems, particularly for systems that pump blood. A certain heat-exchanger system used to heat blood or other fluids may be used to provide whole-body hyperthermic treatments or regional hyperthermic chemotherapy treatments. A disposable unit may be used to separate the fluid path from the fluid control systems. The disposable unit typically includes a heat-exchanger component that is received by a corresponding heat exchanger in a base unit. Fluid pumped through the heat-exchanger component is heated by the heat exchanger.
摘要翻译： 本发明的实施例一般涉及可用于加热或冷却诸如血液的流体的热交换器系统。 可以在这种系统中使用提供低剪切和低湍流的杓式泵，特别是用于泵送血液的系统。 用于加热血液或其他液体的某种热交换器系统可用于提供全身热疗治疗或局部高热化疗治疗。 可以使用一次性单元来将流体路径与流体控制系统分离。 一次性单元通常包括由基本单元中的相应热交换器接收的热交换器部件。 泵送通过热交换器部件的流体被热交换器加热。
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3.发明授权公开(公告)号：US08979788B2
公开(公告)日：2015-03-17
申请号：US13361312
申请日：2012-01-30
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1086 , A61M1/3666 , A61M1/3667 , A61M2205/127 , Y10T137/86035
摘要： A cardiopulmonary bypass system utilizing membrane-based reciprocating positive displacement blood pumps (“pod pumps”). In one aspect, the pod pumps are constructed to provide reduced shear forces on the blood being pumped. In another aspect blood flow through the pod pumps can be controlled by a controller using information from pressure sensors in the control chamber of the pod pumps. In another aspect, the pod pumps are included on a disposable unit that can be received and held by a receptacle means on a base unit, the base unit also providing pressurized control fluid to the pod pumps on the disposable unit through the receptacle means.
摘要翻译： 一种使用膜式往复式正位移血液泵（“荚式泵”）的体外循环系统。 在一个方面，荚果泵构造成在被泵送的血液上提供减小的剪切力。 在另一方面，通过容器泵的血液流动可以由控制器使用来自荚果泵的控制室中的压力传感器的信息来控制。 在另一方面，所述荚式泵包括在一次性单元中，所述一次性单元可以由基座单元上的容器装置接收和保持，所述基座单元还通过所述容器装置向所述一次性单元上的所述容器泵提供加压控制流体。
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4.发明申请公开(公告)号：US20120130298A1
公开(公告)日：2012-05-24
申请号：US13361312
申请日：2012-01-30
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1086 , A61M1/3666 , A61M1/3667 , A61M2205/127 , Y10T137/86035
摘要： A cardiopulmonary bypass system utilizing membrane-based reciprocating positive displacement blood pumps (“pod pumps”). In one aspect, the pod pumps are constructed to provide reduced shear forces on the blood being pumped. In another aspect blood flow through the pod pumps can he controlled by a controller using information from pressure sensors in the control chamber of the pod pumps. In another aspect, the pod pumps are included on a disposable unit that can be received and held by a receptacle means on a base unit, the base unit also providing pressurized control fluid to the pod pumps on the disposable unit through the receptacle means.
摘要翻译： 一种使用膜式往复式正位移血液泵（“荚式泵”）的体外循环系统。 在一个方面，荚果泵构造成在被泵送的血液上提供减小的剪切力。 在另一方面，通过荚果泵的血流可以由控制器使用来自荚果泵的控制室中的压力传感器的信息来控制。 在另一方面，所述荚式泵包括在一次性单元中，所述一次性单元可以由基座单元上的容器装置接收和保持，所述基座单元还通过所述容器装置向所述一次性单元上的所述容器泵提供加压控制流体。
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5.发明授权公开(公告)号：US08105265B2
公开(公告)日：2012-01-31
申请号：US12249668
申请日：2008-10-10
IPC分类号： A61M37/00
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1086 , A61M1/3666 , A61M1/3667 , A61M2205/127 , Y10T137/86035
摘要： A cardiopulmonary bypass system utilizing membrane-based reciprocating positive displacement blood pumps (“pod pumps”). In one aspect, the pod pumps are constructed to provide reduced shear forces on the blood being pumped. In another aspect blood flow through the pod pumps can be controlled by a controller using information from pressure sensors in the control chamber of the pod pumps. In another aspect, the pod pumps are included on a disposable unit that can be received and held by a receptacle means on a base unit, the base unit also providing pressurized control fluid to the pod pumps on the disposable unit through the receptacle means.
摘要翻译： 一种使用膜式往复式正位移血液泵（“荚式泵”）的体外循环系统。 在一个方面，荚果泵构造成在被泵送的血液上提供减小的剪切力。 在另一方面，通过容器泵的血液流动可以由控制器使用来自荚果泵的控制室中的压力传感器的信息来控制。 在另一方面，所述荚式泵包括在一次性单元中，所述一次性单元可以由基座单元上的容器装置接收和保持，所述基座单元还通过所述容器装置向所述一次性单元上的所述容器泵提供加压控制流体。
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6.发明申请公开(公告)号：US20090099498A1
公开(公告)日：2009-04-16
申请号：US12249668
申请日：2008-10-10
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1086 , A61M1/3666 , A61M1/3667 , A61M2205/127 , Y10T137/86035
摘要： A cardiopulmonary bypass system utilizing membrane-based reciprocating positive displacement blood pumps (“pod pumps”). In one aspect, the pod pumps are constructed to provide reduced shear forces on the blood being pumped. In another aspect blood flow through the pod pumps can be controlled by a controller using information from pressure sensors in the control chamber of the pod pumps. In another aspect, the pod pumps are included on a disposable unit that can be received and held by a receptacle means on a base unit, the base unit also providing pressurized control fluid to the pod pumps on the disposable unit through the receptacle means.
摘要翻译： 一种使用膜式往复式正位移血液泵（“荚式泵”）的体外循环系统。 在一个方面，荚果泵构造成在被泵送的血液上提供减小的剪切力。 在另一方面，通过容器泵的血液流动可以由控制器使用来自荚果泵的控制室中的压力传感器的信息来控制。 在另一方面，所述荚式泵包括在一次性单元中，所述一次性单元可以由基座单元上的容器装置接收和保持，所述基座单元还通过所述容器装置向所述一次性单元上的所述容器泵提供加压控制流体。
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公开(公告)号：US20080175719A1
公开(公告)日：2008-07-24
申请号：US11787212
申请日：2007-04-13
申请人： Brian Tracey , Larry B. Gray , Jason A. Demers , James D. Dale , N. Christopher Perry , Michael J. Wilt , Scott A. Leonard
发明人： Brian Tracey , Larry B. Gray , Jason A. Demers , James D. Dale , N. Christopher Perry , Michael J. Wilt , Scott A. Leonard
IPC分类号： F04B43/00
CPC分类号： A61M1/106 , A61F7/12 , A61F2007/0069 , A61F2007/126 , A61M1/1006 , A61M1/1012 , A61M1/1037 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/3626 , A61M1/369 , A61M2205/12 , A61M2205/127 , A61M2205/27 , A61M2205/3334 , A61M2205/3368 , A61M2205/3606 , A61M2205/3653 , A61M2205/502 , F04B43/0054 , F04B43/06 , F04B43/0736 , G01K1/08 , G01K1/16 , G01M3/188
摘要： Embodiments of the present invention relate generally to certain types of reciprocating positive-displacement pumps (which may be referred to hereinafter as “pods,” “pump pods,” or “pod pumps”) used to pump fluids, such as a biological fluid (e.g., blood or peritoneal fluid), a therapeutic fluid (e.g., a medication solution), or a surfactant fluid. The pumps may be configured specifically to impart low shear forces and low turbulence on the fluid as the fluid is pumped from an inlet to an outlet. Such pumps may be particularly useful in pumping fluids that may be damaged by such shear forces (e.g., blood, and particularly heated blood, which is prone to hemolysis) or turbulence (e.g., surfactants or other fluids that may foam or otherwise be damaged or become unstable in the presence of turbulence).
摘要翻译： 本发明的实施例一般涉及用于泵送流体的某些类型的往复式正排量泵（以下称为“舱”，“泵舱”或“舱泵”），例如生物流体 例如血液或腹膜液），治疗液（例如药物溶液）或表面活性剂流体。 泵可以被特别地构造成当流体从入口泵送到出口时在液体上施加低剪切力和低湍流。 这种泵可能特别可用于泵送可能被这种剪切力（例如，血液，特别是加热的血液易于溶血）或湍流（例如，可能发泡或以其他方式损坏的表面活性剂或其它流体） 在湍流的存在下变得不稳定）。
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公开(公告)号：US08292594B2
公开(公告)日：2012-10-23
申请号：US11787212
申请日：2007-04-13
申请人： Brian Tracey , Larry B. Gray , Jason A. Demers , James D. Dale , N. Christopher Perry , Michael J. Wilt , Scott A. Leonard
发明人： Brian Tracey , Larry B. Gray , Jason A. Demers , James D. Dale , N. Christopher Perry , Michael J. Wilt , Scott A. Leonard
CPC分类号： A61M1/106 , A61F7/12 , A61F2007/0069 , A61F2007/126 , A61M1/1006 , A61M1/1012 , A61M1/1037 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/3626 , A61M1/369 , A61M2205/12 , A61M2205/127 , A61M2205/27 , A61M2205/3334 , A61M2205/3368 , A61M2205/3606 , A61M2205/3653 , A61M2205/502 , F04B43/0054 , F04B43/06 , F04B43/0736 , G01K1/08 , G01K1/16 , G01M3/188
摘要： Certain types of reciprocating positive-displacement pumps (which may be referred to hereinafter as “pods,” “pump pods,” or “pod pumps”) are used to pump fluids, such as a biological fluid (e.g., blood or peritoneal fluid), a therapeutic fluid (e.g., a medication solution), or a surfactant fluid. The pumps may be configured specifically to impart low shear forces and low turbulence on the fluid as the fluid is pumped from an inlet to an outlet. Such pumps may be particularly useful in pumping fluids that may be damaged by such shear forces (e.g., blood, and particularly heated blood, which is prone to hemolysis) or turbulence (e.g., surfactants or other fluids that may foam or otherwise be damaged or become unstable in the presence of turbulence).
摘要翻译： 使用某些类型的往复式正排量泵（以下称为荚果，泵荚果或荚果泵）来泵送流体，例如生物流体（例如血液或腹膜液），治疗流体（例如， ，药物溶液）或表面活性剂流体。 泵可以被特别地构造成当流体从入口泵送到出口时在液体上施加低剪切力和低湍流。 这种泵可能特别可用于泵送可能被这种剪切力（例如，血液，特别是加热的血液易于溶血）或湍流（例如，可能发泡或以其他方式损坏的表面活性剂或其它流体） 在湍流的存在下变得不稳定）。
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公开(公告)号：US08158102B2
公开(公告)日：2012-04-17
申请号：US10696969
申请日：2003-10-30
申请人： Jason A. Demers , James D. Dale , Brian Tracey , David W. McGill , Larry B. Gray
发明人： Jason A. Demers , James D. Dale , Brian Tracey , David W. McGill , Larry B. Gray
CPC分类号： B01F13/1013 , A61M1/0281 , A61M1/3687 , A61M2205/12 , B01F13/1016 , B01F15/0202 , B01F2015/0221
摘要： A system, device, and method for mixing a substance with a liquid pumps the liquid into a container of the substance to produce a solution. The container may be part of a container assembly including a port assembly for coupling with the container to produce an inlet and/or and outlet port for the container. The container assembly may be received within a receiving chamber for causing the coupling. The solution may be permitted to flow out of the outlet port when the solution rises within the container to a level of the outlet port so that the substance is partially diluted before flowing out of the outlet port.
摘要翻译： 用于将物质与液体混合的系统，装置和方法将液体泵送到物质的容器中以产生溶液。 容器可以是容器组件的一部分，其包括用于与容器联接以产生用于容器的入口和/或出口的端口组件。 容器组件可以被容纳在接收室内以引起联接。 当溶液在容器内升高到出口端口的水平面时，溶液可能被允许流出出口，使得物质在流出出口之前被部分地稀释。
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公开(公告)号：US07726362B2
公开(公告)日：2010-06-01
申请号：US11927101
申请日：2007-10-29
申请人： Jason A. Demers , James D. Dale , Brian Tracey , David W. McGill , Larry B. Gray
发明人： Jason A. Demers , James D. Dale , Brian Tracey , David W. McGill , Larry B. Gray
IPC分类号： B65B1/04
CPC分类号： B01F13/1013 , A61M1/0281 , A61M1/3687 , A61M2205/12 , B01F13/1016 , B01F15/0202 , B01F2015/0221
摘要： A system, device, and method for mixing a substance with a liquid pumps the liquid into a container of the substance to produce a solution. The container may be part of a container assembly including a port assembly for coupling with the container to produce an inlet and/or and outlet port for the container. The container assembly may be received within a receiving chamber for causing the coupling. The solution may be permitted to flow out of the outlet port when the solution rises within the container to a level of the outlet port so that the substance is partially diluted before flowing out of the outlet port.
摘要翻译： 用于将物质与液体混合的系统，装置和方法将液体泵送到物质的容器中以产生溶液。 容器可以是容器组件的一部分，其包括用于与容器联接以产生用于容器的入口和/或出口的端口组件。 容器组件可以被容纳在接收室内以引起联接。 当溶液在容器内升高到出口端口的水平面时，溶液可能被允许流出出口，使得物质在流出出口之前被部分地稀释。
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