公开(公告)号：US08491184B2

公开(公告)日：2013-07-23

申请号：US12038474

申请日：2008-02-27

Applicant: Dean Kamen ,  N. Christopher Perry ,  Jason A. Demers ,  Brian Tracey ,  Arun D. Chawan ,  Kevin L. Grant

Inventor： Dean Kamen ,  N. Christopher Perry ,  Jason A. Demers ,  Brian Tracey ,  Arun D. Chawan ,  Kevin L. Grant

IPC: G01N25/18 ,  G01K1/08 ,  G01K13/00 ,  G01K7/00 ,  B01D61/00

CPC classification number: G01N25/18

Abstract: A sensor apparatus and sensor apparatus system for use in conjunction with a cassette, including a disposable or replaceable cassette. In some embodiments, the cassette includes a thermal well for permitting the sensing of various properties of a subject media. The thermal well includes a hollow housing of a thermally conductive material. In other embodiments, the cassette includes sensor leads for sensing of various properties of a subject media. The thermal well has an inner surface shaped so as to form a mating relationship with a sensing probe. The mating thermally couples the inner surface with a sensing probe. In some embodiments, the thermal well is located on a disposable portion and the sensing probe on a reusable portion.

公开(公告)号：US08042563B2

公开(公告)日：2011-10-25

申请号：US12038648

申请日：2008-02-27

Applicant: Michael J. Wilt ,  Kevin L. Grant ,  James D. Dale ,  Jason A. Demers ,  Brian Tracey

Inventor： Michael J. Wilt ,  Kevin L. Grant ,  James D. Dale ,  Jason A. Demers ,  Brian Tracey

IPC: G05D11/00

CPC classification number: F04B43/06 ,  A61M1/1006 ,  A61M1/1037 ,  A61M1/1062 ,  A61M1/16 ,  A61M1/1601 ,  A61M1/1639 ,  A61M2205/12 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3331 ,  A61M2205/3368 ,  F04B45/053 ,  Y10T137/0329 ,  Y10T137/2521 ,  Y10T137/2931 ,  Y10T137/7879 ,  Y10T137/85978 ,  Y10T137/86139

Abstract: A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

公开(公告)号：US07794141B2

公开(公告)日：2010-09-14

申请号：US11787112

申请日：2007-04-13

Applicant: N. Christopher Perry ,  Jason A. Demers ,  Brian Tracey

Inventor： N. Christopher Perry ,  Jason A. Demers ,  Brian Tracey

IPC: G01N25/18

CPC classification number: A61M1/106 ,  A61F7/12 ,  A61F2007/0069 ,  A61F2007/126 ,  A61M1/1006 ,  A61M1/1012 ,  A61M1/1037 ,  A61M1/1062 ,  A61M1/1086 ,  A61M1/1087 ,  A61M1/1096 ,  A61M1/3626 ,  A61M1/369 ,  A61M2205/12 ,  A61M2205/127 ,  A61M2205/27 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/3606 ,  A61M2205/3653 ,  A61M2205/502 ,  F04B43/0054 ,  F04B43/06 ,  F04B43/0736 ,  G01K1/08 ,  G01K1/16 ,  G01M3/188

Abstract: A sensing probe is described. The sensing probe includes a probe housing having a probe tip. A thermal sensor in the housing is also included. The thermal sensor has a sensing end and a connector end, where the sensing end is thermally coupled to the probe tip. Also included are at least two leads. The leads transfer electrical signals that are used to determine temperature and conductivity. Also included is a thermal well. The thermal well includes a hollow housing of a thermally conductive material. The housing has an outer surface and an inner surface. The inner surface is a predetermined shape so as to form a mating relationship with a sensing probe. The mating thermally couples the inner surface with a sensing probe. In some embodiments, the thermal well is located on a disposable portion and the sensing probe on a reusable portion.

Abstract translation: 描述了感测探头。 感测探头包括具有探针尖端的探针壳体。 还包括外壳中的热传感器。 热传感器具有感测端和连接器端，其中感测端热耦合到探针尖端。 还包括至少两个潜在客户。 引线传输用于确定温度和电导率的电信号。 还包括一个热井。 热井包括导热材料的中空壳体。 壳体具有外表面和内表面。 内表面是预定的形状，以便与传感探针形成配合关系。 配对将内表面与传感探头热耦合。 在一些实施例中，热井位于可重复使用部分上的一次性部分上，并且感测探针位于可重复使用的部分上。

公开(公告)号：US20090008331A1

公开(公告)日：2009-01-08

申请号：US12072908

申请日：2008-02-27

Applicant: Michael J. Wilt ,  Jason A. Demers ,  Kevin L. Grant ,  Brian Tracey ,  James D. Dale

Inventor： Michael J. Wilt ,  Jason A. Demers ,  Kevin L. Grant ,  Brian Tracey ,  James D. Dale

IPC: B01D61/26 ,  B01D61/24 ,  A61M1/14 ,  F16K31/12 ,  F04B23/02 ,  B01D61/28

CPC classification number: A61M1/3672 ,  A61M1/16 ,  A61M1/1601 ,  A61M1/1621 ,  A61M1/1654 ,  A61M1/1694 ,  A61M1/267 ,  A61M1/3413 ,  A61M1/3424 ,  A61M1/3609 ,  A61M1/3621 ,  A61M1/3638 ,  A61M1/3643 ,  A61M1/3644 ,  A61M1/3646 ,  A61M1/3649 ,  A61M1/365 ,  A61M1/3652 ,  A61M2205/12 ,  A61M2205/123 ,  A61M2205/128 ,  A61M2205/15 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/36 ,  A61M2205/505 ,  Y10T137/87893

Abstract: The present invention generally relates to hemodialysis and similar dialysis systems, including a variety of systems and methods that would make hemodialysis more efficient, easier, and/or more affordable. One aspect of the invention is generally directed to new fluid circuits for fluid flow. In one set of embodiments, a hemodialysis system may include a blood flow path and a dialysate flow path, where the dialysate flow path includes one or more of a balancing circuit, a mixing circuit, and/or a directing circuit. Preparation of dialysate by the preparation circuit, in some instances, may be decoupled from patient dialysis. In some cases, the circuits are defined, at least partially, within one or more cassettes, optionally interconnected with conduits, pumps, or the like. In one embodiment, the fluid circuit and/or the various fluid flow paths may be at least partially isolated, spatially and/or thermally, from electrical components of the hemodialysis system. In some cases, a gas supply may be provided in fluid communication with the dialysate flow path and/or the dialyzer that, when activated, is able to urge dialysate to pass through the dialyzer and urge blood in the blood flow path back to the patient. Such a system may be useful, for example, in certain emergency situations (e.g., a power failure) where it is desirable to return as much blood to the patient as possible. The hemodialysis system may also include, in another aspect of the invention, one or more fluid handling devices, such as pumps, valves, mixers, or the like, which can be actuated using a control fluid, such as air. In some cases, the control fluid may be delivered to the fluid handling devices using an external pump or other device, which may be detachable in certain instances. In one embodiment, one or more of the fluid handling devices may be generally rigid (e.g., having a spheroid shape), optionally with a diaphragm contained within the device, dividing it into first and second compartments.

公开(公告)号：US20080253911A1

公开(公告)日：2008-10-16

申请号：US11871787

申请日：2007-10-12

Applicant: Jason A. Demers ,  Michael J. Wilt ,  Kevin L. Grant ,  James D. Dale ,  Brian Tracey

Inventor： Jason A. Demers ,  Michael J. Wilt ,  Kevin L. Grant ,  James D. Dale ,  Brian Tracey

IPC: F04B43/08

Abstract: A pump cassette is disclosed. The pump cassette includes housing. The housing includes at least one fluid inlet line and at least one fluid outlet line. Also, the cassette includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps at least one fluid from the fluid inlet line to at least one of the fluid outlet line. Also, the cassette includes at least one mixing chamber within the housing. The mixing chamber is fluidly connected to the fluid outlet line.

Abstract translation: 公开了一种泵盒。 泵盒包括壳体。 壳体包括至少一个流体入口管线和至少一个流体出口管线。 而且，该盒子在壳体内包括至少一个往复式压力位移膜泵。 压力泵将至少一种流体从流体入口管泵送到流体出口管线中的至少一个。 此外，盒子在壳体内包括至少一个混合室。 混合室流体地连接到流体出口管线。

公开(公告)号：US20080208103A1

公开(公告)日：2008-08-28

申请号：US11871680

申请日：2007-10-12

Applicant: Jason A. Demers ,  Michael J. Wilt ,  Kevin L. Grant ,  James D. Dale ,  Brian Tracey

Inventor： Jason A. Demers ,  Michael J. Wilt ,  Kevin L. Grant ,  James D. Dale ,  Brian Tracey

IPC: F04B43/08 ,  A61M37/00

CPC classification number: F04B53/10 ,  A61M1/1006 ,  A61M1/1037 ,  A61M1/106 ,  A61M1/1062 ,  A61M1/1087 ,  A61M1/1096 ,  A61M1/16 ,  A61M1/1605 ,  A61M1/1639 ,  A61M1/1656 ,  A61M1/1664 ,  A61M1/1666 ,  A61M1/287 ,  A61M2205/12 ,  A61M2205/128 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3368 ,  F04B7/02 ,  F04B9/109 ,  F04B13/02 ,  F04B23/06 ,  F04B41/06 ,  F04B43/00 ,  F04B43/02 ,  F04B43/06 ,  F04B43/073 ,  F04B43/0733 ,  F04B43/0736 ,  F04B45/02 ,  F04B45/0536 ,  F04B49/22 ,  F04B53/06 ,  F04B53/16 ,  F17D3/00 ,  Y10T137/0324 ,  Y10T137/0379 ,  Y10T137/2521 ,  Y10T137/85978 ,  Y10T137/86139

Abstract: A pump cassette is disclosed. The pump cassette includes a housing having at least, one fluid inlet line and at least one fluid outlet line. The cassette also includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps a fluid from the fluid inlet line to the fluid outlet line. A hollow spike is also included on the housing as well as at least one metering pump The metering pump is fluidly connected to the hollow spike on the housing and to a metering pump fluid line. The metering pump fluid line is fluidly connected to the fluid outlet line.

Abstract translation: 公开了一种泵盒。 泵盒包括具有至少一个流体入口管线和至少一个流体出口管线的壳体。 该盒还包括在壳体内的至少一个往复式压力位移膜泵。 压力泵将流体从流体入口管泵送到流体出口管线。 外壳上还包括一个中空尖钉以及至少一个计量泵。计量泵流体连接到外壳上的中空尖头和计量泵流体管线。 计量泵流体管线流体地连接到流体出口管线。

公开(公告)号：US20080110523A1

公开(公告)日：2008-05-15

申请号：US11927101

申请日：2007-10-29

Applicant: Jason D. Demers ,  James D. Dale ,  Brian Tracey ,  David W. McGill ,  Larry B. Gray

Inventor： Jason D. Demers ,  James D. Dale ,  Brian Tracey ,  David W. McGill ,  Larry B. Gray

IPC: B65B3/04 ,  B65D25/08

CPC classification number: B01F13/1013 ,  A61M1/0281 ,  A61M1/3687 ,  A61M2205/12 ,  B01F13/1016 ,  B01F15/0202 ,  B01F2015/0221

Abstract: A system, device, and method for mixing a substance with a liquid pumps the liquid into a container of the substance to produce a solution. The container may be part of a container assembly including a port assembly for coupling with the container to produce an inlet and/or and outlet port for the container. The container assembly may be received within a receiving chamber for causing the coupling. The solution may be permitted to flow out of the outlet port when the solution rises within the container to a level of the outlet port so that the substance is partially diluted before flowing out of the outlet port.

Abstract translation: 用于将物质与液体混合的系统，装置和方法将液体泵送到物质的容器中以产生溶液。 容器可以是容器组件的一部分，其包括用于与容器联接以产生用于容器的入口和/或出口的端口组件。 容器组件可以被容纳在接收室内以引起联接。 当溶液在容器内升高到出口端口的水平面时，溶液可能被允许流出出口，使得物质在流出出口之前被部分地稀释。

公开(公告)号：US20080108928A1

公开(公告)日：2008-05-08

申请号：US11926811

申请日：2007-10-29

Applicant: Dean Kamen ,  Larry Gray ,  Matthew Harris ,  Richard Lanigan ,  Craig Steinfels ,  Brian Tracey

Inventor： Dean Kamen ,  Larry Gray ,  Matthew Harris ,  Richard Lanigan ,  Craig Steinfels ,  Brian Tracey

IPC: A61M35/00

CPC classification number: A61M35/006

Abstract: A method for packaging an agent for delivery within a body cavity. A reservoir within a package contains a specified quantity of the agent and is either contiguous with, or coupled to, a dispensing node such as a swab. Depth of insertion of the dispensing node into the body cavity is restricted to a specified depth by a penetration-restricting feature that forms part of the package.

公开(公告)号：US20050095154A1

公开(公告)日：2005-05-05

申请号：US10697450

申请日：2003-10-30

Applicant: Brian Tracey ,  David McGill

Inventor： Brian Tracey ,  David McGill

IPC: A61L2/00 ,  A61L2/24 ,  A61M1/02 ,  A61M1/36 ,  B01F3/08 ,  B01F5/00 ,  B01F5/12 ,  B01F13/10 ,  B01F15/02 ,  B01F15/04 ,  F04B1/00 ,  F04B43/073 ,  F04B43/08 ,  F04B43/12 ,  F04B45/06 ,  G05D11/13

CPC classification number: F04B53/16 ,  A61L2/0088 ,  A61L2/24 ,  A61M1/0213 ,  A61M1/0272 ,  A61M1/0281 ,  A61M1/3687 ,  A61M2205/125 ,  B01F3/0865 ,  B01F3/088 ,  B01F5/0077 ,  B01F5/12 ,  B01F13/1013 ,  B01F13/1016 ,  B01F15/0202 ,  B01F15/0475 ,  B01F2015/0221 ,  F04B43/0009 ,  F04B43/06 ,  F04B49/22 ,  F04B53/22 ,  G05D11/132 ,  Y10T29/53 ,  Y10T137/0329 ,  Y10T137/0352 ,  Y10T137/86131 ,  Y10T137/87652 ,  Y10T292/0911 ,  Y10T292/212 ,  Y10T292/438

Abstract: A bezel and bezel assembly in which the bezel is a rigid block with a plurality of cavities. A depression in the block has ribs extending up therefrom to form an elevated contour. The depression includes at least one cavity therein for the application of air pressure into the depression and over the elevated contour. A gasket fits over the bezel so that positive pressure applied through the at least one cavity in the depression forces a gasket membrane to expand away from the pumping side and negative pressure applied through the at least one cavity in the depression pulls the gasket membrane against the elevated contour of the ribs. The bezel may include solvent bondable tubing connections for making pneumatic connections to the bezel.

Abstract translation: 挡板和挡板组件，其中挡板是具有多个空腔的刚性块。 块中的凹陷具有从其延伸的肋以形成升高的轮廓。 凹陷包括至少一个空腔，用于将空气压力施加到凹陷中并且在升高的轮廓上。 垫圈装配在挡板上，使得通过凹陷中的至少一个空腔施加的正压迫使垫圈膜从泵送侧膨胀，并且通过凹陷中的至少一个空腔施加的负压将衬垫膜抵靠 肋骨的轮廓升高。 挡板可以包括用于与挡板进行气动连接的溶剂粘合的管道连接。

公开(公告)号：US09173996B2

公开(公告)日：2015-11-03

申请号：US11533882

申请日：2006-09-21

Applicant: Larry B. Gray ,  Jared Hamilton ,  Richard Lanigan ,  Brian Tracey

Inventor： Larry B. Gray ,  Jared Hamilton ,  Richard Lanigan ,  Brian Tracey

IPC: A61M5/178 ,  A61M5/145 ,  A61M5/158 ,  A61M5/14 ,  A61M5/142 ,  A61M25/06 ,  A61M39/10 ,  A61M39/14

CPC classification number: A61M5/158 ,  A61M5/14 ,  A61M5/142 ,  A61M5/1452 ,  A61M5/1456 ,  A61M25/0612 ,  A61M39/1011 ,  A61M39/14 ,  A61M2005/14573 ,  A61M2005/1581 ,  A61M2005/1585 ,  A61M2005/1587

Abstract: A medical device for delivery of a fluid to a patient from a line terminating in a tubing needle. The medical device includes a cannula assembly for coupling the fluid into a cannula that is inserted into the patient. The cannula assembly has a first locking element disposed in a fixed position with respect to the cannula. Coupling the line to the cannula assembly is an infusion flap. The infusion flap includes a second locking element for engaging the first locking element of the cannula assembly and a lift tab for disconnecting the infusion flap from the cannula assembly. Coupling of the first and second locking elements requires initial mating of the infusion flap and cannula assembly followed by locking through rotation of the infusion flap with respect to the cannula assembly.