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公开(公告)号:US11905299B2
公开(公告)日:2024-02-20
申请号:US17317041
申请日:2021-05-11
Applicant: Gilead Sciences, Inc.
Inventor: Elizabeth M. Bacon , Gayatri Balan , Chien-Hung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D401/12 , C07D498/04 , C07D405/14 , C07D413/14 , C07D409/14 , C07D417/14 , C07D471/04 , C07D495/04 , C07D401/14 , C07B59/00
CPC classification number: C07D498/04 , C07B59/002 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D495/04 , C07B2200/05
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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公开(公告)号:US11066414B2
公开(公告)日:2021-07-20
申请号:US16717074
申请日:2019-12-17
Applicant: Gilead Sciences, Inc.
Inventor: Elizabeth M. Bacon , Gayatri Balan , Chien-Hung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D401/14 , C07D498/04 , C07D405/14 , C07D413/14 , C07D401/12 , C07D409/14 , C07D417/14 , C07D471/04 , C07D495/04 , C07B59/00
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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公开(公告)号:US20170008873A1
公开(公告)日:2017-01-12
申请号:US15199779
申请日:2016-06-30
Applicant: Gilead Sciences, Inc.
Inventor: Elizabeth M. Bacon , Gayatri Balan , Chien-Hung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D401/12 , C07D413/12 , C07D413/14 , C07D417/14 , C07D409/14 , C07F7/08 , C07D453/02 , C07D401/14 , C07D405/14
CPC classification number: C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/14 , C07D453/02 , C07F7/0814
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
Abstract translation: 本公开一般涉及Cot(癌症大阪甲状腺)的调节剂及其使用和制造方法。
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公开(公告)号:US12161625B2
公开(公告)日:2024-12-10
申请号:US18059806
申请日:2022-11-29
Applicant: Gilead Sciences, Inc.
Inventor: Jinfa Du , Joshua A. Kaplan , Thorsten A. Kirschberg , Tetsuya Kobayashi , Scott E. Lazerwith , Rick Andrew Lee , Jonathan William Medley , Michael L. Mitchell , Philip Anthony Morganelli , Hyung-Jung Pyun , Sophia L. Shevick , Neil H. Squires , William J. Watkins
IPC: A61K31/403 , A61K31/03 , A61K31/16 , A61K31/38 , A61K31/4192 , A61P31/20 , C07D487/04 , C07D519/00
Abstract: This application relates generally to certain substituted pyrrolizine compounds, and pharmaceutical compositions which inhibit HBV replication, and methods of making and using them.
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公开(公告)号:US10316017B2
公开(公告)日:2019-06-11
申请号:US15697755
申请日:2017-09-07
Applicant: Gilead Sciences, Inc.
Inventor: Elizabeth M. Bacon , Gayatri Balan , Chien-Hung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D401/12 , C07D453/02 , C07D417/14 , C07D413/14 , C07D413/12 , C07D409/14 , C07D405/14 , C07D401/14 , C07F7/08
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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公开(公告)号:US20180002316A1
公开(公告)日:2018-01-04
申请号:US15634314
申请日:2017-06-27
Applicant: Gilead Sciences, Inc.
Inventor: Gayatri Balan , Chien-Hung Chou , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Roland D. Saito , Neil H. Squires , James G. Taylor , William J. Watkins , Nathan E. Wright
IPC: C07D403/12 , C07D401/14 , C07D405/14 , C07D417/14
CPC classification number: C07D403/12 , C07D401/14 , C07D405/14 , C07D417/14
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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公开(公告)号:US08822430B2
公开(公告)日:2014-09-02
申请号:US13956195
申请日:2013-07-31
Applicant: Gilead Sciences, Inc.
Inventor: Elizabeth M. Bacon , Eda Canales , Aesop Cho , Jeromy J. Cottell , Manoj C. Desai , Michael Graupe , Hongyan Guo , Randall L. Halcomb , Darryl Kato , Choung U. Kim , Thorsten A. Kirschberg , Evan S. Krygowski , Scott E. Lazerwith , John O. Link , Hongtao Liu , Qi Liu , Richard L. Mackman , Michael L. Mitchell , Jay P. Parrish , Hyung-Jung Pyun , Joseph H. Saugier , Scott D. Schroeder , Jianyu Sun , James G. Taylor , James D. Trenkle , Winston C. Tse , Randall W. Vivian , William J. Watkins , Lianhong Xu
IPC: C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/04 , C07D417/04 , C07D417/14 , C07D495/04 , A61K31/4178 , A61K31/7068 , A61K31/7052 , A61K31/4184 , A61P1/16 , A61P31/14
CPC classification number: C07D403/14 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/427 , A61K31/435 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/519 , A61K31/5377 , A61K31/5415 , A61K31/55 , A61K45/06 , A61P31/12 , C07D207/16 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D491/113 , C07D495/04 , C07F5/025
Abstract: The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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公开(公告)号:US10577352B2
公开(公告)日:2020-03-03
申请号:US16045518
申请日:2018-07-25
Applicant: Gilead Sciences, Inc.
Inventor: Gayatri Balan , Chienhung Chou , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Roland D. Saito , Neil H. Squires , James G. Taylor , William J. Watkins , Nathan E. Wright
IPC: C07D401/14 , C07D403/12 , C07D405/14 , C07D417/14
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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公开(公告)号:US20200061024A1
公开(公告)日:2020-02-27
申请号:US16403247
申请日:2019-05-03
Applicant: GILEAD SCIENCES, INC.
Inventor: Jinfa Du , Joshua A. Kaplan , Thorsten A. Kirschberg , Tetsuya Kobayashi , Scott E. Lazerwith , Rick Andrew Lee , Jonathan William Medley , Michael L. Mitchell , Philip Anthony Morganelli , Hyung-Jung Pyun , Sophia L. Shevick , Neil H. Squires , William J. Watkins
IPC: A61K31/403 , A61K31/4192 , A61K31/38 , A61K31/16 , A61K31/03 , A61P31/20 , C07D519/00 , C07D487/04
Abstract: This application relates generally to certain substituted pyrrolizine compounds, and pharmaceutical compositions which inhibit HBV replication, and methods of making and using them.
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公开(公告)号:US20190248807A1
公开(公告)日:2019-08-15
申请号:US16391673
申请日:2019-04-23
Applicant: Gilead Sciences, Inc.
Inventor: Elizabeth M. Bacon , Gayatri Balan , Chienhung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary B. Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D498/04 , C07D495/04 , C07D471/04 , C07D417/14 , C07D409/14 , C07B59/00 , C07D413/14 , C07D405/14 , C07D401/14 , C07D401/12
CPC classification number: C07D498/04 , C07B59/002 , C07B2200/05 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D495/04
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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