公开(公告)号：US12054612B2

公开(公告)日：2024-08-06

申请号：US17561133

申请日：2021-12-23

Applicant: Industrial Technology Research Institute

Inventor： Yun-Chung Teng ,  Jen-Huang Huang ,  Ying-Wen Shen ,  Yu-Bing Liou ,  Hsin-Yi Hsu ,  Li-Hsin Lin ,  Yuchi Wang ,  Hsin-Hsin Shen

IPC: C08L89/06 ,  A61L27/26 ,  A61L27/52 ,  B33Y80/00 ,  C08J3/24 ,  C12N5/00

CPC classification number: C08L89/06 ,  A61L27/26 ,  A61L27/52 ,  B33Y80/00 ,  C08J3/24 ,  C12N5/0018 ,  C08J2389/06 ,  C08J2489/06 ,  C08L2203/02 ,  C08L2205/02 ,  C08L2205/16 ,  C08L2312/00 ,  C12N2500/34

Abstract: A bioprintable material is provided. The bioprintable material includes a hydrogel and microfilaments mixed in the hydrogel. The hydrogel includes a first collagen. The microfilament includes a second collagen. The diameter of the microfilament is ranging from 5 microns to 200 microns. The weight ratio of the microfilaments to the first collagen is ranging from 0.01:1 to 10:1.

公开(公告)号：US11760853B2

公开(公告)日：2023-09-19

申请号：US17537728

申请日：2021-11-30

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Wei-Hong Chang ,  Ching-Mei Chen ,  Grace H. Chen ,  Hsin-Hsin Shen ,  Yuchi Wang ,  Ming-Chia Yang ,  Li-Hsin Lin ,  Sen-Lu Chen ,  Yi-Hsuan Lee ,  Jian-Wei Lin ,  Liang-Cheng Su

IPC: C08J5/18 ,  A61L24/04 ,  B32B27/36 ,  B32B9/02 ,  B32B9/04

CPC classification number: C08J5/18 ,  A61L24/043 ,  B32B9/02 ,  B32B9/045 ,  B32B27/36 ,  C08J2335/02 ,  A61L24/043 ,  C08L5/04 ,  A61L24/043 ,  C08L67/04 ,  A61L24/043 ,  C08L29/04 ,  A61L24/043 ,  C08L71/02

Abstract: An anti-curling film is provided. The anti-curling film includes a first portion and a second portion covering the first portion. The first portion includes polylactic acid (PLA), polycaprolactone (PCL), polyethylene glycol dimethacrylate (PEGDMA) and a photoinitiator. The second portion includes polycaprolactone (PCL), gelatin, hyaluronic acid (HA), alginate (AA), polyvinyl alcohol (PVA) or a combination thereof.

公开(公告)号：US11103446B2

公开(公告)日：2021-08-31

申请号：US16731966

申请日：2019-12-31

Applicant: Industrial Technology Research Institute

Inventor： Yu-Bing Liou ,  Hsin-Yi Hsu ,  Ying-Wen Shen ,  Yun-Chung Teng ,  Yuchi Wang ,  Hsin-Hsin Shen

IPC: A61K9/00 ,  A61K47/42 ,  A61K47/34 ,  A61K47/32 ,  A61K45/06

Abstract: An ophthalmic drug delivery device and a method for fabricating the same are provided. The ophthalmic drug delivery device includes a shield element and a drug release element. The shield element has a light transmittance more than or equal to 80%. The drug release element is an annular body so that the drug release element surrounds the shield element. The drug release element is neutral and includes a cross-linked neutral collagen, a first hydrophilic biodegradable polymer and a drug. The shield element is acidic and includes a cross-linked acidic collagen and a second hydrophilic biodegradable polymer.

公开(公告)号：US12227759B2

公开(公告)日：2025-02-18

申请号：US17126942

申请日：2020-12-18

Applicant: Industrial Technology Research Institute

Inventor： Chia-Jung Lu ,  Jing-En Huang ,  Liang-Cheng Su ,  Hsin-Hsin Shen ,  Yuchi Wang ,  Ying-Hsueh Chao ,  Li-Hsin Lin ,  Hsiu-Hua Huang

IPC: C12N5/00 ,  A61K9/00 ,  A61K35/12 ,  A61K47/38 ,  A61K47/42

Abstract: A temperature-sensitive cell culture composition is provided. The temperature-sensitive cell culture composition includes a hydrogel, a cellulose, a gelatin and a collagen. Based on 1 part by weight of the collagen, a content of the hydrogel is between 0.03 parts by weight and 60 parts by weight, a content of the cellulose is between 150 parts by weight and 360 parts by weight, and a content of the gelatin is between 21 parts by weight and 12 parts by weight. In addition, a method for using the temperature-sensitive cell culture composition, a method for forming the temperature-sensitive cell culture composition, and a use of the temperature-sensitive cell culture composition are also provided.