公开(公告)号：US12152272B2

公开(公告)日：2024-11-26

申请号：US18527656

申请日：2023-12-04

Applicant: IntegenX Inc.

Inventor： David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich ,  Dennis Lehto ,  Kaiwan Chear ,  James Klevenberg ,  Chungsoo Charles Park ,  Corey M. Smith ,  Philip Justus Wunderle ,  David King

IPC: C12Q1/6806 ,  B01L3/00 ,  C12Q1/686 ,  G01N27/447

Abstract: An instrument includes a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to close off a fluidic channel in the body. A cartridge interface is configured to engage the cartridge.

公开(公告)号：US12141884B2

公开(公告)日：2024-11-12

申请号：US17500690

申请日：2021-10-13

Applicant: IntegenX Inc.

Inventor： Robert A. Schueren ,  David King ,  Stevan B. Jovanovich

IPC: G01N33/48 ,  G01N33/50 ,  G06F16/11 ,  G06Q10/0631 ,  G06Q30/0601 ,  G06Q50/00 ,  G06Q50/18 ,  G06Q50/26 ,  G16B50/00 ,  H04W36/30 ,  H04W56/00 ,  H04W72/21 ,  H04W76/19 ,  H04W76/27 ,  H04W4/12

Abstract: Provided herein is a system and method for review of forensic report computer files. The method can involve notifying a plurality of service providers of a job to be performed, accepting a bid from a service provider to perform the job, providing the computer file to the service provider, receiving from the service provider a forensic result such as a reviewed file.

公开(公告)号：US20240175075A1

公开(公告)日：2024-05-30

申请号：US18527656

申请日：2023-12-04

Applicant: IntegenX Inc.

Inventor： David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich ,  Dennis Lehto ,  Kaiwan Chear ,  James Klevenberg ,  Chungsoo Charles Park ,  Corey M. Smith ,  Philip Justus Wunderle ,  David King

IPC: C12Q1/6806 ,  B01L3/00 ,  C12Q1/686 ,  G01N27/447

CPC classification number: C12Q1/6806 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502738 ,  C12Q1/686 ,  G01N27/44743 ,  G01N27/44791 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/041 ,  B01L2300/0654 ,  B01L2300/0681 ,  B01L2300/0848 ,  B01L2300/087 ,  B01L2300/123 ,  B01L2400/0406 ,  B01L2400/0478

Abstract: An instrument includes a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to close off a fluidic channel in the body. A cartridge interface is configured to engage the cartridge.

公开(公告)号：US11891650B2

公开(公告)日：2024-02-06

申请号：US17181228

申请日：2021-02-22

Applicant: INTEGENX, INC.

Inventor： David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich ,  Dennis Lehto ,  Kaiwan Chear ,  James Klevenberg ,  Chungsoo Charles Park ,  Corey M. Smith ,  Philip Justus Wunderle ,  David King

IPC: C12Q1/6806 ,  B01L3/00 ,  C12Q1/686 ,  G01N27/447

CPC classification number: C12Q1/6806 ,  B01L3/50273 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/502738 ,  C12Q1/686 ,  G01N27/44743 ,  G01N27/44791 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/041 ,  B01L2300/0654 ,  B01L2300/0681 ,  B01L2300/087 ,  B01L2300/0848 ,  B01L2300/123 ,  B01L2400/0406 ,  B01L2400/0478 ,  C12Q1/6806 ,  C12Q1/6846 ,  C12Q2565/629

Abstract: Provided herein is a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to crush and close off a fluidic channel in the body. Also provided are a cartridge interface configured to engage the cartridge. Also provided is a system including a cartridge interface and methods of using the cartridge and system.

公开(公告)号：US20210278427A1

公开(公告)日：2021-09-09

申请号：US17211212

申请日：2021-03-24

Applicant: INTEGENX INC.

Inventor： James Ogg ,  David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich

IPC: G01N35/00 ,  B01L3/00 ,  B01L7/00 ,  C12Q1/6818 ,  C12Q1/686 ,  C12Q1/6888

Abstract: Provided herein are instruments and cartridges for processing samples. The cartridges include fluidic circuits in which fluid movement can be regulated by diaphragm valves. In certain cartridges, deformable material providing a diaphragm contacts an interface in the instrument that actuates the diaphragm directly, without intervening actuation layer. Certain cartridges have a plurality of fluidic circuits and fluid distribution channels or pneumatic distribution channels configured to deliver fluids or pneumatic pressure to any of the fluidic circuits, selectively. Certain cartridges have compartments containing on-board reagents. Compartments can be closed by a film attached to a body the cartridge through a heat seal.

公开(公告)号：US10989723B2

公开(公告)日：2021-04-27

申请号：US16258412

申请日：2019-01-25

Applicant: IntegenX Inc.

Inventor： James Ogg ,  David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich

IPC: B01L3/00 ,  G01N35/00 ,  B01L7/00 ,  C12Q1/6818 ,  C12Q1/686 ,  C12Q1/6888

Abstract: Provided herein are instruments and cartridges for processing samples. The cartridges include fluidic circuits in which fluid movement can be regulated by diaphragm valves. In certain cartridges, deformable material providing a diaphragm contacts an interface in the instrument that actuates the diaphragm directly, without intervening actuation layer. Certain cartridges have a plurality of fluidic circuits and fluid distribution channels or pneumatic distribution channels configured to deliver fluids or pneumatic pressure to any of the fluidic circuits, selectively. Certain cartridges have compartments containing on-board reagents. Compartments can be closed by a film attached to a body the cartridge through a heat seal.

公开(公告)号：US10961561B2

公开(公告)日：2021-03-30

申请号：US16250646

申请日：2019-01-17

Applicant: IntegenX, Inc.

Inventor： David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich ,  Dennis Lehto ,  Kaiwan Chear ,  James Klevenberg ,  Chungsoo Charles Park ,  Corey M. Smith ,  Philip Justus Wunderle ,  David King

IPC: B01L3/00 ,  G01N1/10 ,  C12Q1/6806 ,  C12Q1/686 ,  G01N27/447

Abstract: Provided herein is a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to crush and close off a fluidic channel in the body. Also provided are a cartridge interface configured to engage the cartridge. Also provided is a system including a cartridge interface and methods of using the cartridge and system.

公开(公告)号：US20250156978A1

公开(公告)日：2025-05-15

申请号：US19019858

申请日：2025-01-14

Applicant: IntegenX Inc.

Inventor： Robert A. Schueren ,  David King ,  Stevan B. Jovanovich

IPC: G06Q50/26 ,  G06F16/11 ,  G06Q10/0631 ,  G06Q30/0601 ,  G06Q50/00 ,  G06Q50/18 ,  G16B50/00 ,  H04W4/12 ,  H04W36/30 ,  H04W56/00 ,  H04W72/21 ,  H04W76/19 ,  H04W76/27

Abstract: A system for automated forensic data analysis includes a processor in communication with stored instructions, wherein upon execution of the instructions the processor is configured to: analyze a forensic biological data file; and determine, based on the analysis, that the forensic biological data file does not meet a quality criteria for forensic searching. In response to determining the quality criteria is not met, the processor is configured to automatically initiate communication with one or more remote computers to request a review of the forensic biological data file; and receive information about the review.

公开(公告)号：US20190256890A1

公开(公告)日：2019-08-22

申请号：US16250646

申请日：2019-01-17

Applicant: IntegenX, Inc.

Inventor： David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich ,  Dennis Lehto ,  Kaiwan Chear ,  James Klevenberg ,  Chungsoo Charles Park ,  Corey M. Smith ,  Philip Justus Wunderle ,  David King

IPC: C12Q1/6806 ,  B01L3/00 ,  C12Q1/686 ,  G01N27/447

Abstract: Provided herein is a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to crush and close off a fluidic channel in the body. Also provided are a cartridge interface configured to engage the cartridge. Also provided is a system including a cartridge interface and methods of using the cartridge and system.

公开(公告)号：US10208332B2

公开(公告)日：2019-02-19

申请号：US15117053

申请日：2015-04-30

Applicant: IntegenX Inc.

Inventor： David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich ,  Dennis Lehto ,  Kaiwan Chear ,  James Klevenberg ,  Chungsoo Charles Park ,  Corey Smith ,  Philip Justus Wunderle ,  David King

IPC: A61J1/06 ,  B01L3/00 ,  G01N21/00 ,  G01N15/06 ,  C12Q1/6806 ,  C12Q1/686 ,  G01N27/447

Abstract: Provided herein is a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to crush and close off a fluidic channel in the body. Also provided are a cartridge interface configured to engage the cartridge. Also provided is a system including a cartridge interface and methods of using the cartridge and system.