公开(公告)号：US20060264776A1

公开(公告)日：2006-11-23

申请号：US11132109

申请日：2005-05-18

申请人： Jeffrey Stahmann ,  John Hatlestad ,  Jesse Hartley ,  Richard Fogoros

发明人： Jeffrey Stahmann ,  John Hatlestad ,  Jesse Hartley ,  Richard Fogoros

IPC分类号： A61B5/05

CPC分类号： A61B5/0205 ,  A61B5/0031 ,  A61B5/0535 ,  A61B5/1116 ,  A61B5/4869 ,  A61N1/36521 ,  A61N1/36535

摘要： This patent document discusses systems, devices, and methods for increasing a sensitivity or specificity of thoracic fluid detection in a subject and differentiating between pleural effusion and pulmonary edema. In one example, a thoracic impedance measurement circuit senses a thoracic impedance signal. In another example, a processor receives the thoracic impedance signal and determines whether such thoracic impedance signal is “significant.” A significant thoracic impedance signal indicates the presence of thoracic fluid and may be recognized by comparing the thoracic impedance signal (or variation thereof) to a thoracic impedance threshold. When a significant thoracic impedance signal is recognized, the processor is adapted to detect one or both of: a pleural effusion indication and a pulmonary edema indication using one or a combination of: physiologic information, patient symptom information, and posture information. In another example, the thoracic impedance threshold is adjusted using such physiologic, patient symptom, or posture information.

摘要翻译： 该专利文献讨论了用于增加受试者胸部液体检测的敏感性或特异性并区分胸腔积液和肺水肿的系统，装置和方法。 在一个示例中，胸部阻抗测量电路感测胸部阻抗信号。 在另一示例中，处理器接收胸部阻抗信号并确定这种胸部阻抗信号是否“显着”。 显着的胸部阻抗信号表示胸腔液的存在，并且可以通过将胸部阻抗信号（或其变化）与胸部阻抗阈值进行比较来识别。 当识别出显着的胸部阻抗信号时，处理器适合于使用生理信息，患者症状信息和姿势信息中的一个或组合来检测胸腔积液指示和肺水肿指示之一或两者。 在另一个例子中，使用这种生理，患者症状或姿势信息来调整胸阻抗阈值。

公开(公告)号：US20080108907A1

公开(公告)日：2008-05-08

申请号：US11972405

申请日：2008-01-10

申请人： Jeffrey Stahmann ,  John Hatlestad ,  Jesse Hartley ,  Richard Fogoros

发明人： Jeffrey Stahmann ,  John Hatlestad ,  Jesse Hartley ,  Richard Fogoros

IPC分类号： A61B5/085

CPC分类号： A61B5/0205 ,  A61B5/0031 ,  A61B5/0535 ,  A61B5/1116 ,  A61B5/4869 ,  A61N1/36521 ,  A61N1/36535

摘要： This patent document discusses systems, devices, and methods for increasing a sensitivity or specificity of thoracic fluid detection in a subject and differentiating between pleural effusion and pulmonary edema. In one example, a thoracic impedance measurement circuit senses a thoracic impedance signal. In another example, a processor receives the thoracic impedance signal and determines whether such thoracic impedance signal is “significant.” A significant thoracic impedance signal indicates the presence of thoracic fluid and may be recognized by comparing the thoracic impedance signal (or variation thereof) to a thoracic impedance threshold. When a significant thoracic impedance signal is recognized, the processor is adapted to detect one or both of: a pleural effusion indication and a pulmonary edema indication using one or a combination of: physiologic information, patient symptom information, and posture information. In another example, the thoracic impedance threshold is adjusted using such physiologic, patient symptom, or posture information.

摘要翻译： 该专利文献讨论了用于增加受试者胸部液体检测的敏感性或特异性并区分胸腔积液和肺水肿的系统，装置和方法。 在一个示例中，胸部阻抗测量电路感测胸部阻抗信号。 在另一示例中，处理器接收胸部阻抗信号并确定这种胸部阻抗信号是否“显着”。 显着的胸部阻抗信号表示胸腔液的存在，并且可以通过将胸部阻抗信号（或其变化）与胸部阻抗阈值进行比较来识别。 当识别出显着的胸部阻抗信号时，处理器适合于使用生理信息，患者症状信息和姿势信息中的一个或组合来检测胸腔积液指示和肺水肿指示之一或两者。 在另一个例子中，使用这种生理，患者症状或姿势信息来调整胸阻抗阈值。

公开(公告)号：US20050074741A1

公开(公告)日：2005-04-07

申请号：US10824776

申请日：2004-04-15

申请人： Kent Lee ,  John Hatlestad ,  Qingsheng Zhu ,  Jeffrey Stahmann ,  Jesse Hartley ,  Quan Ni

发明人： Kent Lee ,  John Hatlestad ,  Qingsheng Zhu ,  Jeffrey Stahmann ,  Jesse Hartley ,  Quan Ni

IPC分类号： A61B5/00 ,  A61B5/0205 ,  A61B5/0476 ,  A61B5/0478 ,  A61B5/0488 ,  A61B5/0496 ,  A61B5/08 ,  A61B5/11 ,  A62B7/00

CPC分类号： A61B5/7264 ,  A61B5/0031 ,  A61B5/0205 ,  A61B5/0476 ,  A61B5/0478 ,  A61B5/0488 ,  A61B5/0496 ,  A61B5/08 ,  A61B5/0809 ,  A61B5/11 ,  A61B5/113 ,  A61B5/1135 ,  A61B5/4818

摘要： Disordered breathing events may be classified as central, obstructive or a combination of central an obstructive in origin based on patient motion associated with respiratory effort. Central disordered breathing is associated with disrupted respiration with reduced respiratory effort. Obstructive disordered breathing is associated with disrupted respiration accompanied by respiratory effort. A disordered breathing classification system includes a disordered breathing detector and a respiratory effort motion sensor. Components of the disordered breathing classification system may be fully or partially implantable.

摘要翻译： 基于与呼吸努力相关的患者运动，无序呼吸事件可被分类为中枢性，阻塞性或中枢性阻塞性组合。 呼吸中枢紊乱与呼吸力下降相关联。 阻塞性无序呼吸与伴随呼吸功能的呼吸中断有关。 无序呼吸分类系统包括无序呼吸检测器和呼吸力运动传感器。 无序呼吸分类系统的组成部分可以完全或部分植入。

公开(公告)号：US20050065447A1

公开(公告)日：2005-03-24

申请号：US10824941

申请日：2004-04-15

申请人： Kent Lee ,  Quan Ni ,  Jesse Hartley ,  John Hatlestad ,  Jeffrey Stahmann

发明人： Kent Lee ,  Quan Ni ,  Jesse Hartley ,  John Hatlestad ,  Jeffrey Stahmann

IPC分类号： A61B5/0205 ,  A61B5/08 ,  A61N1/08

CPC分类号： A61B5/4806 ,  A61B5/0205 ,  A61B5/08 ,  A61B5/082 ,  A61N1/08

摘要： Patient respiration may be characterized using a marked respiration waveform involving a respiration waveform annotated with symbols, markers or other indicators representing one or more respiration characteristics. A respiration waveform may be acquired by sensing a physiological parameter modulated by respiration. A marked respiration waveform may be generated based on the acquired respiration waveform and one or more detected respiration waveform characteristics and/or respiration-related conditions. One or more components used to generate the marked respiratory waveform may be fully or partially implantable.

摘要翻译： 患者呼吸可以使用标示的呼吸波形来表征，该呼吸波形涉及用符号，标记或代表一个或多个呼吸特征的其它指示符注释的呼吸波形。 可以通过感测由呼吸调制的生理参数来获取呼吸波形。 可以基于所获取的呼吸波形和一个或多个检测到的呼吸波形特征和/或呼吸相关条件来生成标记的呼吸波形。 用于产生标记的呼吸波形的一个或多个组件可以是完全或部分可植入的。

公开(公告)号：US20050042589A1

公开(公告)日：2005-02-24

申请号：US10642998

申请日：2003-08-18

申请人： John Hatlestad ,  Quan Ni ,  Jeffrey Stahmann ,  Jesse Hartley ,  Qingsheng Zhu ,  Bruce Kenknight ,  Douglas Daum ,  Kent Lee

发明人： John Hatlestad ,  Quan Ni ,  Jeffrey Stahmann ,  Jesse Hartley ,  Qingsheng Zhu ,  Bruce Kenknight ,  Douglas Daum ,  Kent Lee

IPC分类号： A61B5/00 ,  A61B5/0205 ,  A61B5/0476 ,  A61B5/0488 ,  A61B5/0496 ,  A61B5/08 ,  A61B5/11 ,  A61N1/362 ,  G09B23/28

CPC分类号： A61B5/4815 ,  A61B5/0031 ,  A61B5/0205 ,  A61B5/0476 ,  A61B5/0488 ,  A61B5/0496 ,  A61B5/0809 ,  A61B5/11 ,  A61B5/4528 ,  A61B5/4818 ,  A61N1/3621 ,  G06F19/00

摘要： A sleep quality assessment approach involves collecting data based on detected physiological or non-physiological patient conditions. At least one of detecting patient conditions and collecting data is performed using an implantable device. Sleep quality may be evaluated using the collected data by an imlantable or patient-external sleep quality processor. One approach to sleep quality evaluation involves computing one or more summary metrics based on occurrences of movement disorders or breathing disorders during sleep.

摘要翻译： 睡眠质量评估方法包括基于检测到的生理或非生理性患者状况收集数据。 使用可植入装置执行检测患者状况和收集数据中的至少一个。 睡眠质量可以使用收集的数据由不可变的或患者外部的睡眠质量处理器进行评估。 睡眠质量评估的一种方法包括基于睡眠期间的运动障碍或呼吸障碍的发生来计算一个或多个总结度量。

公开(公告)号：US20050043644A1

公开(公告)日：2005-02-24

申请号：US10643016

申请日：2003-08-18

申请人： Jeffrey Stahmann ,  John Hatlestad ,  Quan Ni ,  Jesse Hartley ,  Douglas Daum ,  Kent Lee

发明人： Jeffrey Stahmann ,  John Hatlestad ,  Quan Ni ,  Jesse Hartley ,  Douglas Daum ,  Kent Lee

IPC分类号： A61B5/00 ,  A61B5/08 ,  A61B5/11 ,  A61N1/362 ,  A61N1/365

CPC分类号： A61B5/02405 ,  A61B5/0031 ,  A61B5/08 ,  A61B5/0816 ,  A61B5/1116 ,  A61B5/1118 ,  A61B5/4812 ,  A61B5/4815 ,  A61B5/4818 ,  A61B2560/0242 ,  A61B2562/0219 ,  A61N1/362 ,  A61N1/36514

摘要： An approach for predicting disordered breathing involves detecting one or more conditions associated with disordered breathing. The detected conditions are compared to disordered breathing prediction criteria. A prediction of disordered breathing is performed based on the comparison of the detected conditions to the prediction criteria. At least one of comparing the detected conditions to the prediction criteria and predicting disordered breathing is performed at least in part implantably.

摘要翻译： 预测无序呼吸的方法涉及检测与无序呼吸相关的一个或多个情况。 将检测到的条件与无序呼吸预测标准进行比较。 基于检测到的条件与预测标准的比较来执行无序呼吸的预测。 将检测到的条件与预测标准进行比较以及预测无序呼吸的至少一个至少部分地可植入地进行。

公开(公告)号：US20060293609A1

公开(公告)日：2006-12-28

申请号：US11126723

申请日：2005-05-11

申请人： Jeffrey Stahmann ,  John Hatlestad ,  Jesse Hartley

发明人： Jeffrey Stahmann ,  John Hatlestad ,  Jesse Hartley

IPC分类号： A61B5/05

CPC分类号： A61B5/053 ,  A61B5/0537 ,  A61B5/4869 ,  A61M2230/40 ,  A61M2230/65 ,  A61N1/36521 ,  A61N1/37282

摘要： This patent document discusses, among other things, systems, devices, and methods for enhancing detection of pulmonary edema using, in addition to thoracic impedance, one or a combination of: physiologic information about a subject, at least one statistical parameter, a user-programmable detection level, at least one parameter associated with a previous pulmonary edema event, and patient symptom information about the subject. In one example, a (base) thoracic impedance threshold is modified to an adjusted thoracic impedance threshold. The adjusted thoracic impedance threshold provides an increased sensitivity of pulmonary edema detection as compared to the base thoracic impedance threshold. In another example, an alert is provided to a subject, a caregiver, or other user based on a pulmonary edema indication determined by the present systems, devices, and methods. In a further example, a therapy (provided to the subject) is adjusted or initiated in response to the pulmonary edema indication.

公开(公告)号：US20060258952A1

公开(公告)日：2006-11-16

申请号：US11126689

申请日：2005-05-11

申请人： Jeffrey Stahmann ,  John Hatlestad ,  Jesse Hartley

发明人： Jeffrey Stahmann ,  John Hatlestad ,  Jesse Hartley

IPC分类号： A61B5/05 ,  A61B5/02 ,  A61B7/00

CPC分类号： A61B5/0537 ,  A61B5/0002 ,  A61B5/0538 ,  A61B5/4869 ,  A61B5/4878

摘要： This patent document discusses, among other things, systems, devices, and methods for enhancing detection of pulmonary edema using, in addition to thoracic impedance, one or a combination of: physiologic information about a subject, at least one statistical parameter, a user-programmable detection level, at least one parameter associated with a previous pulmonary edema event, and patient symptom information about the subject. In one example, a (base) thoracic impedance threshold is modified to an adjusted thoracic impedance threshold. The adjusted thoracic impedance threshold provides an increased sensitivity of pulmonary edema detection as compared to the base thoracic impedance threshold. In another example, an alert is provided to a subject, a caregiver, or other user based on a pulmonary edema indication determined by the present systems, devices, and methods. In a further example, a therapy (provided to the subject) is adjusted or initiated in response to the pulmonary edema indication.

公开(公告)号：US20050080348A1

公开(公告)日：2005-04-14

申请号：US10920568

申请日：2004-08-17

申请人： Jeffrey Stahmann ,  John Hatlestad ,  Jesse Hartley ,  Quan Ni ,  Kent Lee

发明人： Jeffrey Stahmann ,  John Hatlestad ,  Jesse Hartley ,  Quan Ni ,  Kent Lee

IPC分类号： A61B5/08

CPC分类号： A61B5/0803 ,  A61B5/02405 ,  A61N1/3601

摘要： An event-based approach to collecting and organizing information associated with events affecting respiration is presented. The detection or prediction of an event affecting the respiration of a patient initiates acquisition of information associated with the event. The respiratory logbook system acquires information with the event during the event and during intervals proximate in time to the event. The information is organized as a respiratory log entry. The user can access the information by operating a user interface. The information may be presented in textual or graphical form.

摘要翻译： 提出了一种基于事件的方法来收集和组织与影响呼吸的事件相关的信息。 影响患者呼吸的事件的检测或预测启动与事件相关联的信息的获取。 呼吸记录系统在事件期间以及事件发生的时间间隔期间获取事件信息。 信息被组织为呼吸日志条目。 用户可以通过操作用户界面访问信息。 信息可以以文本或图形形式呈现。

公开(公告)号：US20050039745A1

公开(公告)日：2005-02-24

申请号：US10643203

申请日：2003-08-18

申请人： Jeffrey Stahmann ,  John Hatlestad ,  Quan Ni ,  Jesse Hartley ,  Douglas Daum ,  Kent Lee

发明人： Jeffrey Stahmann ,  John Hatlestad ,  Quan Ni ,  Jesse Hartley ,  Douglas Daum ,  Kent Lee

IPC分类号： A61N1/36 ,  A61N1/362 ,  A62B7/00

CPC分类号： A61N1/362 ,  A61N1/3601

摘要： An approach to providing disordered breathing therapy includes detecting disordered breathing and adapting a therapy to mitigate the disordered breathing. The therapy may be adapted to enhance therapy effectiveness, to provide therapy that reduces an impact of the therapy on the patient, or to achieve other therapeutic goals. Cardiac electrical therapy to mitigate the disordered breathing may include various cardiac pacing regimens and/or delivery of non-excitatory electrical stimulation to the heart.

摘要翻译： 提供无序呼吸治疗的方法包括检测无序呼吸并适应治疗以减轻无序呼吸。 治疗可以适应于增强治疗有效性，提供减少治疗对患者的影响或实现其它治疗目标的治疗。 减轻无序呼吸的心脏电疗可能包括各种心脏起搏方案和/或向心脏递送非兴奋性电刺激。