摘要:
A sleep quality assessment approach involves collecting data based on detected physiological or non-physiological patient conditions. At least one of detecting patient conditions and collecting data is performed using an implantable device. Sleep quality may be evaluated using the collected data by an imlantable or patient-external sleep quality processor. One approach to sleep quality evaluation involves computing one or more summary metrics based on occurrences of movement disorders or breathing disorders during sleep.
摘要:
Systems and methods for evaluating a patient condition using autonomic balance information involve providing an implantable cardiac device that acquires a cardiac waveform from a patient. One or more characteristics associated with autonomic balance of the patient are detected and used to evaluate a patient condition, such as sleep onset, sleep stage, cardiac vulnerability over a predetermined duration, and sleep disordered breathing. Patient activity levels may be sensed and used to evaluate the patient's condition, such as for determining a level of systemic stress. Characteristics associated with the autonomic balance include calculating an LF/HF ratio waveform and/or determining one or more morphological features of the LF/HF ratio waveform. Coordination with a patient-external device may facilitate transmission of information about one or more of the cardiac waveform, the one or more characteristics associated with the autonomic balance, and a marked cardiac waveform.
摘要:
This invention provides pacemaker systems comprising (1) an electronic pacemaker, and (2) a biological pacemaker, wherein the biological pacemaker comprises a cell that functionally expresses a chimeric hyperpolarization-activated, cyclic nucleotide-gated (HCN) ion channel at a level effective to induce pacemaker current in the cell. The invention also provides related biological pacemakers, atrioventricular bridges, methods of making same, and methods of treating a subject afflicted with a cardiac rhythm disorder.
摘要:
Systems and methods for correlating biometric trends with a related temporal event are disclosed. A preferred embodiment utilizes an implantable medical device comprising at least one sensor in electronic communication with a patient management system adapted to temporally analyze and correlate biometric data. Some embodiments of a system disclosed herein also can be configured as an Advanced Patient Management system that helps better monitor, predict and manage chronic diseases.
摘要:
A medical system includes a housing configured for implantation within a patient's subclavicular region. Detection circuitry provided in the housing is configured to detect cardiac electrical activity. Energy delivery circuitry provided in the housing is configured to deliver therapy to treat a detected tachycardia or fibrillation episode. A lead is coupled to the housing, detection circuitry, and energy delivery circuitry. The lead is configured for subcutaneous, non-intrathoracic placement within the patient, and extends from the subclavicular region to just below the patient's ribs or the subxiphoid process. A defibrillation electrode is provided at a distal end of the lead body. A pair of sensing electrodes is provided on the lead body at locations consistent with positions V2-V5 of surface electrocardiogram electrodes.
摘要:
An implantable system includes a housing configured for subcutaneous, non-intrathoracic placement in a patient, and a plurality of electrodes coupled to the housing, each of the plurality of electrodes configured for subcutaneous, non-intrathoracic placement in the patient. Detection circuitry is provided in the housing and coupled to the plurality of electrodes. The detection circuitry is configured to detect cardiac activity necessitating a cardiac stimulation therapy. Energy delivery circuitry is provided in the housing and coupled to the plurality of electrodes. The energy delivery circuitry is configured to deliver the cardiac stimulation therapy.
摘要:
Systems and methods for an information management system for an implantable medical device are disclosed. A preferred embodiment uses an implantable medical device that is automatically recognized by a publicly accessible information access portal. Some embodiments of a system disclosed herein also can be configured as a component of an Advanced Patient Management System that helps better monitor, predict and manage chronic diseases.
摘要:
Systems and methods for sleep state classification involve detecting conditions related to sleep, including at least one condition associated with rapid eye movement (REM) sleep. Additionally, a condition modulated by the sleep-wake status of the patient may be detected. A medical system that is partially or fully implantable incorporates sensors and circuitry for detecting and processing the sleep-related signals. A sleep state processor classifies the patient's sleep state based on the sleep-related signals. Sleep state classification may be used in connection with the delivery of sleep state appropriate therapy, diagnostic testing, or patient monitoring.