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公开(公告)号：US06641519B1
公开(公告)日：2003-11-04
申请号：US09788265
申请日：2001-02-16
IPC分类号： A61M3600
CPC分类号： A61N5/1007 , A61N2005/1008
摘要： A drive device in a medical device for driving a wire through a guide tube from a first position with an end of the wire outside an animal body to a second position in which the end is inside the animal body. The drive device comprises first and second elements rotatable relative to each other. The first and second elements each have contact surfaces, that in each rotational position of the first and second elements relative to each other are in contact with each other in a contact area along a common contact plane. A storage space going about the axis is provided for the wire in the first element. The storage space is open along a length of it to the contact surface of the first element. The second element comprises a channel for the wire and is open to the contact plane.
摘要翻译： 一种医疗装置中的驱动装置，用于通过引导管从第一位置驱动电线，其中电线的端部在动物体外部延伸到第二位置，其中端部在动物体内。 驱动装置包括可相对于彼此旋转的第一和第二元件。 第一和第二元件各自具有接触表面，在第一和第二元件的相对于彼此的每个旋转位置中，沿着公共接触平面的接触区域中彼此接触。 为第一个元件中的导线提供围绕轴线的存储空间。 存储空间沿其长度打开到第一元件的接触表面。 第二元件包括用于导线的通道并且对接触平面开放。
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公开(公告)号：US06595908B2
公开(公告)日：2003-07-22
申请号：US09788226
申请日：2001-02-16
IPC分类号： A61M3600
CPC分类号： A61N5/1007 , A61N5/1027 , A61N2005/1008 , A61N2005/1009 , A61N2005/1011
摘要： A modular device for implanting radioactive seeds in an animal body through needles implanted in the body. Trains of radioactive seeds and non-radioactive spacers are assembled in an assembly unit. The assembly unit comprises a device for determining activity of the seeds with an accuracy that allows distinguishing between different activities within tolerance ranges of specified nominal activities for the seeds. After implantation of the seeds in the body a pre-plan may be recalculated taking into consideration actual activities of seeds implanted. Not correctly composed trains may be disposed of. A post-plan may be determined based upon actually measured activities of implanted seeds.
摘要翻译： 用于通过植入体内的针将放射性种子植入动物体内的模块化装置。 放射性种子和非放射性隔离物的火车组装在组装单元中。 组装单元包括用于以准确度确定种子的活动的装置，其允许区分种子指定的标称活动的容许范围内的不同活动。 将种子植入体内后，可以考虑植入种子的实际活动来重新计算预先计划。 不正确组合的火车可能会被处置。 可以基于实际测量的植入种子的活动来确定后期计划。
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3.发明授权Apparatus and method for effecting radiation treatment on a pre-selected anatomical portion of an animal body 有权对动物体的预先选择的解剖部分进行放射治疗的装置和方法公开(公告)号：US09387343B2
公开(公告)日：2016-07-12
申请号：US13367807
申请日：2012-02-07
IPC分类号： A61N5/10
CPC分类号： A61N5/1007 , A61N5/1075 , A61N2005/1008 , A61N2005/1012 , A61N2005/1094
摘要： A medical apparatus for effecting radiation treatment on a pre-selected anatomical portion of an animal body is disclosed. The medical apparatus may include a plurality of treatment channels configured to be positioned adjacent a body tissue and a plurality of delivery channels coupled to a corresponding number of treatment channels. The medical apparatus may also include a plurality of source channels configured to receive one or more energy sources, a tracking channel configured to receive a tracking element, and a connecting element configured to connect each delivery channel with either one of the plurality of sources channels or the tracking channel.
摘要翻译： 公开了一种用于对动物体的预先选择的解剖部分进行放射治疗的医疗装置。 医疗设备可以包括被配置为邻近身体组织定位的多个治疗通道以及耦合到相应数量的治疗通道的多个输送通道。 医疗设备还可以包括被配置为接收一个或多个能量源的多个源通道，被配置为接收跟踪元件的跟踪通道，以及被配置为将每个输送通道与多个源通道中的任一个连接的连接元件 跟踪通道。
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公开(公告)号：US07507197B2
公开(公告)日：2009-03-24
申请号：US10615844
申请日：2003-07-10
IPC分类号： A61N5/00
CPC分类号： A61B18/1485 , A61B18/1477 , A61B2017/00274 , A61B2018/00547 , A61B2018/1425 , A61N5/1007 , A61N2005/1011
摘要： A device for effecting radiation treatment of benign or malign prostate hyperplasia. The device includes a catheter probe having an elongated body with a circumferential surface which is inserted within the urethra towards the prostate. The elongated body has a longitudinal bore extending towards at least one outlet opening present in the circumferential surface near the proximal end. A catheter tube is inserted with a proximal sharp end through the longitudinal bore of the elongated body, with an outlet opening and through the urethral wall towards a desired location within the prostate. A pre-planned amount of radiation is delivered via the catheter tube at a location within the prostate for effecting the radiation treatment. The urethral insertion probe allows a quick and accurate positioning of the catheter probe and the catheter tube relative to the prostate without discomforting the patient. The catheter probe is movably accommodated within the urethral probe.
摘要翻译： 用于进行良性或恶性前列腺增生的放射治疗的装置。 该装置包括具有细长主体的导管探针，其具有朝向前列腺插入尿道内的圆周表面。 细长主体具有朝向近端附近的圆周表面中存在的至少一个出口开口延伸的纵向孔。 导管管插入具有通过细长体的纵向孔的近端尖端，具有出口开口并穿过尿道壁朝向前列腺内的期望位置。 预先计划的辐射量通过前列腺内的一个位置处的导管传送，以进行放射治疗。 尿道插入探针允许导管探针和导管相对于前列腺的快速和准确的定位，而不会使患者不舒服。 导管探针可移动地容纳在尿道探针内。
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5.发明授权Device for implanting a row of radioactive seeds and non-radioactive spacers in an animal body 有权用于在动物体内植入一排放射性种子和非放射性隔离物的装置公开(公告)号：US07288061B2
公开(公告)日：2007-10-30
申请号：US10674356
申请日：2003-10-01
IPC分类号： A61N5/00
CPC分类号： A61N5/1007 , A61N2005/1011 , A61N2005/1023
摘要： A device for implanting radioactive seeds and non-radioactive spacers in a desired configuration in an animal body for effecting radiation therapy. An elongated hollow needle is inserted in the body. A pushing element implants the row of seeds and spacers though the hollow needle towards the desired location. A tube shaped element receives the row of seeds and spacers. A lube shaped sleeve having open ends is used to insert the tube shaped element through the needle and toward the location. The pushing elements pushes the row of seeds and spacers into the desired location while still being carried in the tube shaped element.
摘要翻译： 用于在动物体内植入放射性种子和非放射性间隔物的装置，用于实现放射治疗。 细长的中空针插入体内。 推动元件通过中空针将所述种子和间隔物排排列到期望的位置。 管形元件接收一排种子和间隔物。 使用具有开口端的润滑脂套筒将管形元件穿过针头并朝向该位置。 推动元件将种子和间隔物排推入期望的位置，同时仍被携带在管状元件中。
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6.发明授权After loader apparatus as well as a device for exchanging an after loader cartridge 失效装载机装置以及用于更换后装载机筒的装置公开(公告)号：US07097609B2
公开(公告)日：2006-08-29
申请号：US10382511
申请日：2003-03-07
CPC分类号： G21F5/015 , A61N5/1007 , A61N2005/1008
摘要： The invention relates to an after loader apparatus for treatment of tumours in an animal body comprising a housing with at least one exchangeable radiation source connected to a first end of a transport wire, which wire is connected with its other end to transport means for advancing said transport wire and said radiation source through a guide tube to and from a tumour in said body, where at least the radiation source and the transport wire are mounted in an exchangeable radiation shielded after loader cartridge, which cartridge can be placed in a suitable receptable opening present in said housing.It is an object of the invention to provide an after loader apparatus wherein in a more safe manner to the environment a cartridge containing a radioactive source can be replaced by another cartridge containing a new radioactive source and according to the invention the after loader apparatus is characterized in that, for exchanging said radiation source after use an exchanging device is present for, in a first step, removing the cartridge with the used radiation source from said receptable opening and, in a second step, inserting a further cartridge containing a new radiation source in said receptable opening.The invention relates furthermore to a device for exchanging an after loader cartridge in an after loader apparatus according to the invention.
摘要翻译： 本发明涉及一种用于治疗动物体内的肿瘤的后装载装置，包括具有连接到输送线的第一端的至少一个可交换辐射源的壳体，该导线与其另一端连接到用于推进所述 输送线和所述辐射源通过导管连接到所述主体中的肿瘤，其中至少辐射源和输送线被安装在装载器盒之后屏蔽的可更换辐射中，所述可插入的辐射源可以放置在合适的可接收开口 存在于房屋内。 本发明的目的是提供一种后装载装置，其中以更安全的方式到达环境中，容纳放射源的筒可以被另一个包含新的放射源的筒代替，根据本发明，后装载装置的特征在于 其特征在于，为了在使用之后交换所述辐射源，存在交换装置，用于在第一步骤中用所述可接收的开口用所使用的辐射源去除所述盒，并且在第二步骤中，插入另外的包含新的辐射源的盒 在所述可接收的开口中。 本发明还涉及根据本发明的用于在后装载机装置中更换后装载机筒的装置。
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公开(公告)号：US08301228B2
公开(公告)日：2012-10-30
申请号：US13013051
申请日：2011-01-25
IPC分类号： A61B6/00
CPC分类号： A61N5/1031 , A61N5/1001 , A61N5/1007 , A61N5/1039 , A61N2005/1012 , A61N2005/1032 , A61N2005/1074 , G06F19/00 , G06F19/3481
摘要： The invention relates to a real time radiation treatment planning system for use in effecting radiation therapy of a pre-selected anatomical portion of an animal body using hollow needles. According to embodiments of the invention, the system may include a processing means processing means-configured to perform a three-dimensional imaging algorithm and a three-dimensional image segmentation algorithm, with respect to one or more specific organs within the pre-selected anatomical portion and with respect to the needles, for converting the image data obtained with an imaging means into a three-dimensional image of the anatomical portion, using at least one single or multi-objective anatomy-based genetic optimization algorithm. For pre-planning or virtual simulation purposes, the processing means is arranged to determine in real time the optimal number and position of at least one of the needles, positions of energy emitting sources within the needles, and the dwell times of the energy emitting sources at the positions. For post-planning purposes, the processing means is arranged to determine, based on three-dimensional image information, in real time the real needle positions and the dwell times of the energy emitting sources for the positions.
摘要翻译： 本发明涉及一种实时放射治疗计划系统，用于使用空心针对动物体的预先选择的解剖部分进行放射治疗。 根据本发明的实施例，系统可以包括处理装置处理装置，其被配置为相对于预先选择的解剖部分内的一个或多个特定器官执行三维成像算法和三维图像分割算法 并且相对于针，用于使用至少一个单目标或多目标基于解剖的遗传优化算法将用成像装置获得的图像数据转换成解剖部分的三维图像。 对于预先规划或虚拟模拟目的，处理装置被布置成实时确定针中的至少一个针的最佳数量和位置，针内的能量发射源的位置以及能量发射源的停留时间 在职位。 为了规划后的目的，处理装置被布置成基于三维图像信息实时确定位置的能量发射源的实际针位置和停留时间。
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公开(公告)号：US20100246766A1
公开(公告)日：2010-09-30
申请号：US12665491
申请日：2008-06-17
CPC分类号： A61N5/1001 , H01J35/06 , H01J35/14 , H01J35/16 , H01J2235/062 , H01J2235/081 , H01J2235/087 , H01J2235/164 , H01J2235/165 , H01J2235/205
摘要： A miniature X-ray source device for effecting radiation therapy at least comprising a vacuum tube containing a cathode and an anode spaced apart at some distance from each other; emitting means for emitting free electrons from the cathode; electric field generating means for applying during use a high-voltage electric field between the cathode and the anode for accelerating the emitted free electrons towards the anode, as well as an exit window for X-ray radiation being generating at the anode. The present invention provides an improved miniature X-ray source device, that can also properly be used in treating skin cancer and which is easy to handle. The anode is provided with a flat X-ray emitting surface. In particular, the cathode exhibits a concave shaped surface having a center part surrounded by an upright circumferential edge, wherein the center part of the concave shaped surface is provided with an electron emitting material.
摘要翻译： 一种用于进行放射治疗的微型X射线源装置，至少包括一个真空管，该真空管包含彼此间隔一定距离的阴极和阳极; 用于从阴极发射自由电子的发射装置; 电场产生装置，用于在使用期间施加阴极和阳极之间的高电压电场，用于加速向阳极发射的自由电子，以及在阳极处产生X射线辐射的出射窗口。 本发明提供一种改进的微型X射线源装置，其也可以适当地用于治疗皮肤癌，并且易于处理。 阳极设置有平坦的X射线发射表面。 特别地，阴极具有凹形状的表面，其中心部分被直立的周向边缘包围，其中凹形表面的中心部分设置有电子发射材料。
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9.发明授权Self controlled image guided device and method for inserting a needle in an animal body for effecting radiation therapy in said body 有权自我控制的图像引导装置和用于将针插入动物体中以在所述身体中进行放射治疗的方法公开(公告)号：US07229401B2
公开(公告)日：2007-06-12
申请号：US10301791
申请日：2002-11-22
申请人： Johann Kindlein
发明人： Johann Kindlein
CPC分类号： A61N5/1007 , A61N5/1027 , A61N2005/1011
摘要： The invention relates to a device and method for inserting a needle in an animal body for effecting radiation therapy in the body, including a template for positioning the needles to be inserted, needle drive structure for drive a needle through said template towards a desired location in the body, and real-time imaging structure for creating and presenting an image of the desired location and the position of said needle during the insertion of said needle. Due to the fact that the bevelled tip of a hollow needle cause the needle to diverge away from the “line of insertion or movement” and away from the actual desired position in the animal body adversely affecting the dosimetry quality of the implanted seeds a more accurate insertion of the needle is required. According to the invention the device is provided with adjusting structure for adjusting a movement of said needle towards said desired location during insertion.
摘要翻译： 本发明涉及一种用于将针插入动物身体中用于在体内进行放射治疗的装置和方法，包括用于定位待插入的针的模板，针驱动结构，用于通过所述模板朝向期望的位置驱动针 身体和实时成像结构，用于在插入所述针时产生和呈现期望位置的图像和所述针的位置。 由于中空针头的斜头使得针头离开“插入或移动线”而远离动物体内的实际所需位置，从而不利地影响植入的种子的剂量学质量更准确 需要插针。 根据本发明，该装置设置有用于在插入期间调节所述针朝向所述期望位置的运动的调节结构。
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公开(公告)号：US6137114A
公开(公告)日：2000-10-24
申请号：US983051
申请日：1998-03-26
CPC分类号： G21F5/00 , A61N5/1007 , G21F5/015 , A61N2005/1008
摘要： An irradiation apparatus has at least one exchangeable radiation source that may be moved by means of a transport cable between at least one rest position and at least one irradiation position and a long-distance transport container for radiation sources to be exchanged. In order to reduce the danger of control errors, the rest position is located inside the long-distance transport container and the transport container forms or may form an integral part of the irradiation apparatus. For that purpose, interface elements are provided on the transport container and other parts of the irradiation apparatus. By winding and unwinding the transport cable on and from a feeding drum with a cable-receiving groove at least partially covered by a pressing strip, particularly thin transport cables may be used, so that the width of the pressing strip substantially corresponds to the width of the cable-receiving groove. The pressing strip is helically wound in the cable-receiving groove around the feeding drum, in the axial or radial direction with respect to the feeding drum, and the cable-receiving groove is thus covered in a substantially uninterrupted manner. Means for lifting, preferably also for deflecting and lowering again the pressing strip, may be moved along the transport cable in relation to the feeding drum in order to let free an output joint for the transport cable from the feeding drum.
摘要翻译： PCT No.PCT / EP96 / 03047 Sec。 371日期：1998年3月26日 102（e）1998年3月26日PCT PCT 1996年7月11日PCT公布。 出版物WO97 / 03722 日期1997年2月6日照射装置具有至少一个可更换的辐射源，其可以通过运送电缆在至少一个静止位置和至少一个照射位置之间移动，以及用于要交换的辐射源的长途运输容器 。 为了减少控制误差的危险，休息位置位于长途运输集装箱内，运输容器形成或可形成照射装置的整体部分。 为此，在运送容器和照射装置的其它部分上设置界面元件。 通过将输送缆线卷绕和放出来自至少部分地被压条覆盖的电缆接收槽的进给滚筒上和从其上退绕，可以使用特别细的输送电缆，使得压条的宽度基本上对应于 电缆接收槽。 压带在相对于进料滚筒的轴向或径向方向上围绕进料滚筒螺旋缠绕在电缆接收槽中，因此电缆接收槽以基本不间断的方式被覆盖。 用于提升的装置，优选地也可以用于使压紧带偏转和降低，可以相对于进料滚筒沿着传送缆索移动，以便使输送缆线从进料滚筒释放出来。
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