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公开(公告)号：US20120255373A1
公开(公告)日：2012-10-11
申请号：US13506892
申请日：2012-05-23
申请人： John S. Foster , Daryl W. Grummitt , John C. Harley , James P. Linton , Jaquelin K. Spong , Douglas L. Thompson
发明人： John S. Foster , Daryl W. Grummitt , John C. Harley , James P. Linton , Jaquelin K. Spong , Douglas L. Thompson
IPC分类号： G01N1/28
CPC分类号： C12M47/04 , B01L3/502761 , B01L7/52 , B01L2200/0652 , B01L2300/0816 , B01L2400/043 , B01L2400/0439 , B01L2400/0478 , G01N2015/1081 , G01N2015/149
摘要： A disposable cartridge is described which is equipped with a plurality of microfabricated particle sorting structures. The disposable cartridge may include passageways which connect fluid reservoirs in the cartridge with corresponding microfluidic passageways on the particle sorting structure. A flexible gasket may prevent leakages and allow the fluid to cross the gasket barrier through a plurality of holes in the gasket, allowing fluid to be transferred from the reservoirs to the microfabricated particle sorting structures. The plurality of particle sorting structures may be arranged in the disposable cartridge in order to perform multiple separation operations, such as a sequential or parallel sorting operation.
摘要翻译： 描述了配备有多个微加工颗粒分选结构的一次性盒。 一次性药筒可以包括将药筒中的流体储存器与颗粒分选结构上的相应的微流体通道连接的通道。 柔性垫片可以防止泄漏并允许流体通过垫圈中的多个孔穿过垫圈屏障，允许流体从储存器转移到微加工颗粒分选结构。 多个颗粒分选结构可以布置在一次性盒中，以便执行多个分离操作，例如顺序或并行排序操作。
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公开(公告)号：US08993311B2
公开(公告)日：2015-03-31
申请号：US13506892
申请日：2012-05-23
申请人： John S. Foster , Daryl W. Grummitt , John C. Harley , James P. Linton , Jaquelin K. Spong , Douglas L. Thompson
发明人： John S. Foster , Daryl W. Grummitt , John C. Harley , James P. Linton , Jaquelin K. Spong , Douglas L. Thompson
CPC分类号： C12M47/04 , B01L3/502761 , B01L7/52 , B01L2200/0652 , B01L2300/0816 , B01L2400/043 , B01L2400/0439 , B01L2400/0478 , G01N2015/1081 , G01N2015/149
摘要： A disposable cartridge is described which is equipped with a plurality of microfabricated particle sorting structures. The disposable cartridge may include passageways which connect fluid reservoirs in the cartridge with corresponding microfluidic passageways on the particle sorting structure. A flexible gasket may prevent leakages and allow the fluid to cross the gasket barrier through a plurality of holes in the gasket, allowing fluid to be transferred from the reservoirs to the microfabricated particle sorting structures. The plurality of particle sorting structures may be arranged in the disposable cartridge in order to perform multiple separation operations, such as a sequential or parallel sorting operation.
摘要翻译： 描述了配备有多个微加工颗粒分选结构的一次性盒。 一次性药筒可以包括将药筒中的流体储存器与颗粒分选结构上的相应的微流体通道连接的通道。 柔性垫片可以防止泄漏并允许流体通过垫圈中的多个孔穿过垫圈屏障，允许流体从储存器转移到微加工颗粒分选结构。 多个颗粒分选结构可以布置在一次性盒中，以便执行多个分离操作，例如顺序或并行排序操作。
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公开(公告)号：US20120190105A1
公开(公告)日：2012-07-26
申请号：US13374899
申请日：2012-01-23
CPC分类号： C12M47/04 , B01L3/502761 , B01L7/52 , B01L2200/0652 , B01L2300/0816 , B01L2400/043 , B01L2400/0439 , B01L2400/0478 , B01L2400/0481 , G01N15/1459 , G01N2015/149
摘要： A disposable cartridge is described which is compatible with a MEMS particle sorting device. The disposable cartridge may include passageways which connect fluid reservoirs in the cartridge with corresponding microfluidic passageways on the MEMS chip. A flexible gasket may prevent leakages and allow the fluid to cross the gasket barrier through a plurality of holes in the gasket. Vents and septums may also be included to allow air to escape and fluids to be inserted by hypodermic needle. A MEMS-based particle sorting system using the disposable cartridge is also described.
摘要翻译： 描述了与MEMS颗粒分选装置兼容的一次性盒。 一次性盒可以包括将盒中的流体储存器与MEMS芯片上的相应微流体通道连接的通道。 柔性垫片可以防止泄漏，并允许流体通过垫圈中的多个孔穿过垫圈屏障。 还可以包括通气孔和隔膜，以允许空气逸出，并由皮下注射针插入液体。 还描述了使用一次性盒的基于MEMS的颗粒分选系统。
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公开(公告)号：US08822207B2
公开(公告)日：2014-09-02
申请号：US13374899
申请日：2012-01-23
CPC分类号： C12M47/04 , B01L3/502761 , B01L7/52 , B01L2200/0652 , B01L2300/0816 , B01L2400/043 , B01L2400/0439 , B01L2400/0478 , B01L2400/0481 , G01N15/1459 , G01N2015/149
摘要： A disposable cartridge is described which is compatible with a MEMS particle sorting device. The disposable cartridge may include passageways which connect fluid reservoirs in the cartridge with corresponding microfluidic passageways on the MEMS chip. A flexible gasket may prevent leakages and allow the fluid to cross the gasket barrier through a plurality of holes in the gasket. Vents and septums may also be included to allow air to escape and fluids to be inserted by hypodermic needle. A MEMS-based particle sorting system using the disposable cartridge is also described.
摘要翻译： 描述了与MEMS颗粒分选装置兼容的一次性盒。 一次性盒可以包括将盒中的流体储存器与MEMS芯片上的相应微流体通道连接的通道。 柔性垫片可以防止泄漏，并允许流体通过垫圈中的多个孔穿过垫圈屏障。 还可以包括通气孔和隔膜，以允许空气逸出，并由皮下注射针插入液体。 还描述了使用一次性盒的基于MEMS的颗粒分选系统。
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