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公开(公告)号：US20070221225A1
公开(公告)日：2007-09-27
申请号：US11626770
申请日：2007-01-24
申请人： Larry Kutt , Shaun Wallace , William Reid , Bennett Scharf , Frank Caruso , Tom Damian , Doug Ogden
发明人： Larry Kutt , Shaun Wallace , William Reid , Bennett Scharf , Frank Caruso , Tom Damian , Doug Ogden
CPC分类号： A61M16/0045 , A61G10/023 , A61M16/0051 , A61M16/024 , A61M16/101 , A61M16/107 , A61M2205/17 , A61M2230/205 , A63B23/18 , A63B2213/006
摘要： An altitude simulation system is disclosed for simulating an altitude within an enclosure or mask, wherein various improvements are provided, including: (a) a more effective use hypoxpic air generated by the system via recirculating techniques and improvements in air leakage, (b) improvements in determining when a simulated altitude is reached, (c) improvements in controlling hypoxic air generators so that peak electrical power loads are reduced and there are enhanced failsafe features for protecting the health of users, (d) using a pulse oximetry device for measuring oxygen saturation in a user's blood to thereby vary the oxygen content in the air provided to the user.
摘要翻译： 公开了一种用于模拟外壳或掩模内的高度的高度模拟系统，其中提供了各种改进，包括：（a）通过再循环技术和空气泄漏的改进来更有效地使用系统产生的低氧空气，（b）改进 在确定何时达到模拟高度时，（c）改进控制缺氧空气发生器，使峰值电力负载减小，并且有增强的故障保护功能，以保护用户的健康，（d）使用脉搏血氧仪测量氧气 使用者的血液饱和，从而改变提供给使用者的空气中的氧气含量。
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公开(公告)号：USD738330S1
公开(公告)日：2015-09-08
申请号：US29448963
申请日：2013-03-14
申请人： Allen Braswell, Jr. , Frank Caruso
设计人： Allen Braswell, Jr. , Frank Caruso
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公开(公告)号：USD689612S1
公开(公告)日：2013-09-10
申请号：US29397808
申请日：2011-07-21
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公开(公告)号：US20090028948A1
公开(公告)日：2009-01-29
申请号：US11813116
申请日：2005-12-30
申请人： Trevor Payne , Felix Meiser , Almar Postma , Raffaele Cammarano , James Williams , Paul McCormick , Aaron Dodd , Frank Caruso
发明人： Trevor Payne , Felix Meiser , Almar Postma , Raffaele Cammarano , James Williams , Paul McCormick , Aaron Dodd , Frank Caruso
IPC分类号： A61K9/14 , A61K31/519 , A61K31/551 , A61K31/192 , A61K31/196
CPC分类号： A61K9/5123 , A61K9/5192 , A61K31/192 , A61K31/196 , A61K31/4985 , A61K31/5513
摘要： The present invention relates to improved therapeutically active nanocomposite microstructure compositions, including nanoparticle compositions and nanoparticle preparations. Preferred embodiments include nanoparticle compositions comprising nanoparticles of a therapeutically active agent dispersed in a carrier matrix. The invention also relates to a method for preparing said compositions and preparations using solid-state mechanochemical synthesis. Further, it relates to therapeutic products produced using said compositions and to methods of treatment using the compositions.
摘要翻译： 本发明涉及改进的治疗活性纳米复合微结构组合物，包括纳米颗粒组合物和纳米颗粒制剂。 优选的实施方案包括纳米颗粒组合物，其包含分散在载体基质中的治疗活性剂的纳米颗粒。 本发明还涉及使用固态机械化学合成制备所述组合物和制剂的方法。 此外，它涉及使用所述组合物生产的治疗产品和使用该组合物的治疗方法。
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5.发明申请Polyelectrolyte multilayer films at liquid-liquid interfaces and methods for providing and using same 有权液 - 液界面的聚电解质多层膜及其提供和使用方法公开(公告)号：US20090023155A1
公开(公告)日：2009-01-22
申请号：US11483891
申请日：2006-07-10
CPC分类号： C08J5/20 , G01N21/6428
摘要： The present invention is directed to methods for providing a polyelectrolyte multilayer film at a liquid-liquid interface. Such methods include steps of sequentially-depositing layers of cationic and anionic polyelectrolytes at a liquid-liquid interface that is formed between immiscible first and second liquids whereby a polyelectrolyte multilayer film is provided at the liquid-liquid interface. In certain preferred embodiments, the first liquid is an aqueous solution and the second liquid is a liquid crystal. In alternative embodiments, the first liquid is an aqueous solution and the second liquid is an oil. The invention further encompasses polyelectrolyte multilayer films provided by the disclosed methods as well as applications utilizing such materials.
摘要翻译： 本发明涉及在液 - 液界面处提供聚电解质多层膜的方法。 这样的方法包括在不混溶的第一和第二液体之间形成的液 - 液界面顺序地沉积阳离子和阴离子聚电解质层，由此在液 - 液界面处提供聚电解质多层膜。 在某些优选实施方案中，第一液体是水溶液，第二液体是液晶。 在替代实施例中，第一液体是水溶液，第二液体是油。 本发明还包括通过所公开的方法提供的聚电解质多层膜以及利用这种材料的应用。
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公开(公告)号：US07045146B2
公开(公告)日：2006-05-16
申请号：US10148890
申请日：2001-01-12
申请人： Frank Caruso , Dieter Trau , Helmuth Möhwald , Reinhard Renneberg
发明人： Frank Caruso , Dieter Trau , Helmuth Möhwald , Reinhard Renneberg
CPC分类号： A61K8/11 , A23P10/30 , A61K9/5089 , A61K2800/412 , A61K2800/434 , A61Q19/00 , B01J13/10 , B01J13/22
摘要： Process for encapsulation of an uncharged crystalline solid particle include treating the crystalline solid particle material with amphiphilic substances and subsequently coating the material with a layer of charged polyelectrolyte or coating the material with a multilayer comprising alternating layers of oppositely charged polyelectrolytes.
摘要翻译： 用于封装不带电的结晶固体颗粒的方法包括用两亲物质处理结晶固体颗粒材料，随后用一层带电聚电解质涂覆该材料，或用包含相反电荷的聚电解质交替层的多层涂覆该材料。
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公开(公告)号：US20070129434A1
公开(公告)日：2007-06-07
申请号：US10501692
申请日：2004-07-15
IPC分类号： A61K31/24
CPC分类号： C07D207/267 , A61K31/40 , A61K31/44 , C07D207/06 , C07D207/20 , C07D207/22 , C07D209/96 , C07D401/04
摘要： A method for inducing analgesia and/or inhibiting abuse of abusive substances includes administration of d-methadone metabolites or their structural analogs. The d-methadone metabolites, EMDP and EDDP, and their structural analogs may be incorporated into a suitable pharmaceutical composition for administration to patients. The invention includes the method itself, certain structural analogs, and pharmaceutical compositions for use in accordance with the method.
摘要翻译： 用于诱导镇痛和/或抑制滥用滥用物质的方法包括给予美沙酮代谢物或其结构类似物。 d美沙酮代谢物，EMDP和EDDP及其结构类似物可以并入用于给予患者的合适的药物组合物中。 本发明包括方法本身，某些结构类似物和根据该方法使用的药物组合物。
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公开(公告)号：US07101575B2
公开(公告)日：2006-09-05
申请号：US10376386
申请日：2003-02-27
申请人： Edwin Donath , Gleb B. Sukhorukov , Karl-Heinz Lerche , Andreas Voigt , Hans Bäumler , Frank Caruso , Helmuth Möhwald
发明人： Edwin Donath , Gleb B. Sukhorukov , Karl-Heinz Lerche , Andreas Voigt , Hans Bäumler , Frank Caruso , Helmuth Möhwald
IPC分类号： A61K9/48
CPC分类号： A61K9/5138 , A61K9/5015 , A61K9/5026 , A61K9/5031 , A61K9/5052 , A61K9/5073 , A61K9/5089 , A61K9/51 , A61K9/5192 , B01J13/02 , B01J13/22
摘要： The invention relates to capsules coated with a polyelectrolyte shell and methods for the production thereof.
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公开(公告)号：USD725779S1
公开(公告)日：2015-03-31
申请号：US29482408
申请日：2014-02-18
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公开(公告)号：US08062853B2
公开(公告)日：2011-11-22
申请号：US12685209
申请日：2010-01-11
IPC分类号： G01N33/53
CPC分类号： C08J5/20 , G01N21/6428
摘要： The present invention is directed to methods for providing a polyelectrolyte multilayer film at a liquid-liquid interface. Such methods include steps of sequentially-depositing layers of cationic and anionic polyelectrolytes at a liquid-liquid interface that is formed between immiscible first and second liquids whereby a polyelectrolyte multilayer film is provided at the liquid-liquid interface. In certain preferred embodiments, the first liquid is an aqueous solution and the second liquid is a liquid crystal. In alternative embodiments, the first liquid is an aqueous solution and the second liquid is an oil. The invention further encompasses polyelectrolyte multilayer films provided by the disclosed methods as well as applications utilizing such materials.
摘要翻译： 本发明涉及在液 - 液界面处提供聚电解质多层膜的方法。 这样的方法包括在不混溶的第一和第二液体之间形成的液 - 液界面顺序地沉积阳离子和阴离子聚电解质层，由此在液 - 液界面处提供聚电解质多层膜。 在某些优选实施方案中，第一液体是水溶液，第二液体是液晶。 在替代实施例中，第一液体是水溶液，第二液体是油。 本发明还包括通过所公开的方法提供的聚电解质多层膜以及利用这种材料的应用。
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