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    FUNCTIONAL IMAGING
    1.
    发明申请
    FUNCTIONAL IMAGING 失效
    功能成像

    公开(公告)号：US20110293143A1

    公开(公告)日：2011-12-01

    申请号：US13147402

    申请日：2010-01-12

    申请人： Manoj V. Narayanan ,  Jens-Christoph Georgi ,  Frank O. Thiele ,  Ralph Brinks ,  Michael Perkuhn

    发明人： Manoj V. Narayanan ,  Jens-Christoph Georgi ,  Frank O. Thiele ,  Ralph Brinks ,  Michael Perkuhn

    IPC分类号： G06K9/00

    CPC分类号： G06T7/0028 ,  A61B6/037 ,  G06T7/33 ,  G06T2207/10104 ,  G06T2207/30004 ,  G06T2207/30204

    摘要： A method includes generating a kinetic parameter value for a VOI in a functional image of a subject based on motion corrected projection data using an iterative algorithm, including determining a motion correction for projection data corresponding to the VOI based on the VOI, motion correcting the projection data corresponding to the VOI to generate the motion corrected projection data, and estimating the at least one kinetic parameter value based on the motion corrected projection data or image data generated with the motion corrected projection data. In another embodiment, a method includes registering functional image data indicative of tracer uptake in a scanned patient with image data from a different imaging modality, identifying a VOI in the image based on the registered images, generating at least one kinetic parameter for the VOI, and generating a feature vector including the at least one generated kinetic parameter and at least one bio- marker.

    摘要翻译： 一种方法包括：使用迭代算法，基于运动校正的投影数据，生成用于对象的功能图像中的VOI的动力学参数值，包括基于所述VOI确定对应于所述VOI的投影数据的运动校正，校正所述投影的运动 对应于VOI的数据以生成运动校正的投影数据，以及基于运动校正的投影数据或利用运动校正的投影数据生成的图像数据来估计至少一个动力学参数值。 在另一个实施例中，一种方法包括将来自不同成像模式的图像数据指示在扫描患者中的示踪剂吸收的功能图像数据，基于注册图像识别图像中的VOI，为VOI生成至少一个动力学参数， 以及生成包括所述至少一个生成的动力学参数和至少一个生物标志物的特征向量。

    Functional imaging
    2.
    发明授权
    Functional imaging 失效
    功能成像

    公开(公告)号：US08787643B2

    公开(公告)日：2014-07-22

    申请号：US13147402

    申请日：2010-01-12

    申请人： Manoj V. Narayanan ,  Jens-Christoph Georgi ,  Frank O. Thiele ,  Ralph Brinks ,  Michael Perkuhn

    发明人： Manoj V. Narayanan ,  Jens-Christoph Georgi ,  Frank O. Thiele ,  Ralph Brinks ,  Michael Perkuhn

    IPC分类号： G06K9/00 ,  G06T7/00 ,  A61B6/00

    CPC分类号： G06T7/0028 ,  A61B6/037 ,  G06T7/33 ,  G06T2207/10104 ,  G06T2207/30004 ,  G06T2207/30204

    摘要： A method includes generating a kinetic parameter value for a VOI in a functional image of a subject based on motion corrected projection data using an iterative algorithm, including determining a motion correction for projection data corresponding to the VOI based on the VOI, motion correcting the projection data corresponding to the VOI to generate the motion corrected projection data, and estimating the at least one kinetic parameter value based on the motion corrected projection data or image data generated with the motion corrected projection data. In another embodiment, a method includes registering functional image data indicative of tracer uptake in a scanned patient with image data from a different imaging modality, identifying a VOI in the image based on the registered images, generating at least one kinetic parameter for the VOI, and generating a feature vector including the at least one generated kinetic parameter and at least one bio-marker.

    摘要翻译： 一种方法包括：使用迭代算法，基于运动校正的投影数据，生成用于对象的功能图像中的VOI的动力学参数值，包括基于所述VOI确定对应于所述VOI的投影数据的运动校正，校正所述投影的运动 对应于VOI的数据以生成运动校正的投影数据，以及基于运动校正的投影数据或利用运动校正的投影数据生成的图像数据来估计至少一个动力学参数值。 在另一个实施例中，一种方法包括将来自不同成像模式的图像数据指示在扫描患者中的示踪剂吸收的功能图像数据，基于注册图像识别图像中的VOI，为VOI生成至少一个动力学参数， 以及生成包括所述至少一个生成的动力学参数和至少一个生物标记的特征向量。

    Wearable device for bioelectrical interaction with motion artifact correction means
    3.
    发明申请
    Wearable device for bioelectrical interaction with motion artifact correction means 失效
    用于与运动伪像校正装置进行生物电相互作用的穿戴装置

    公开(公告)号：US20060149146A1

    公开(公告)日：2006-07-06

    申请号：US10537886

    申请日：2003-12-08

    申请人： Ralf Schmidt ,  Olaf Such ,  Christian Reichinger ,  Michael Perkuhn ,  Harald Reiter ,  Andras Montvay ,  Josef Lauter

    发明人： Ralf Schmidt ,  Olaf Such ,  Christian Reichinger ,  Michael Perkuhn ,  Harald Reiter ,  Andras Montvay ,  Josef Lauter

    IPC分类号： A61B5/04

    CPC分类号： A61B5/02 ,  A61B5/0006 ,  A61B5/02438 ,  A61B5/02444 ,  A61B5/0404 ,  A61B5/0408 ,  A61B5/6843 ,  A61B2562/02 ,  A61B2562/0247 ,  A61B2562/046

    摘要： The invention relates to a wearable device arranged for enabling a bioelectrical interaction with an individual when being brought into contact with the individual's skin I, said device comprising electrodes 2 arranged to carry out said interaction by means of a first electrical signal, said electrodes comprise motion artifact detection means 4. The electrode assembly 1 comprises the electrode 2 arranged to carry out a bioelectrical interaction with the individual by means of measuring an electrical signal on the body of the individual I and/or applying an electrical signal to the body of the individual. In order to enable said bioelectrical interaction the electrode 2 is provided with an electrical cable 2a. According to the invention, the electrode 2 is arranged with a pressure sensor 4. The pressure sensor 4 is arranged to measure a normal force component of an external force applied to the electrode due to movement of the individual. Preferably the pressure sensor 4 is a force/pressure sensitive resistor or a capacitive pressure sensor. The pressure sensor is arranged to produce an electrical signal, referred to as the second signal, the magnitude of the second signal being proportional to the pressure load. The pressure sensor 4 is arranged with cables 4a, 4b for purposes of signal processing.

    摘要翻译： 本发明涉及一种穿戴式装置，其被布置成当与个人的皮肤I接触时能够与个人进行生物电相互作用，所述装置包括布置成通过第一电信号执行所述相互作用的电极2，所述电极包括运动 电极组件1包括布置成通过测量个体I的身体上的电信号和/或向个体的身体施加电信号来与个体进行生物电相互作用的电极2 。 为了使所述生物电相互作用，电极2设置有电缆2a。 根据本发明，电极2配置有压力传感器4.压力传感器4布置成测量由于个体的移动而施加到电极的外力的法向力分量。 优选地，压力传感器4是力/压敏电阻器或电容式压力传感器。 压力传感器被布置成产生称为第二信号的电信号，第二信号的幅度与压力负载成正比。 为了信号处理的目的，压力传感器4配置有电缆4a，4b。

    System and Method for Detecting and Predicting a Syncope Event
    5.
    发明申请
    System and Method for Detecting and Predicting a Syncope Event 审中-公开
    用于检测和预测晕厥事件的系统和方法

    公开(公告)号：US20080228088A1

    公开(公告)日：2008-09-18

    申请号：US12064998

    申请日：2006-08-23

    申请人： Xavier Aubert ,  Jens Muhlsteff ,  Michael Perkuhn

    发明人： Xavier Aubert ,  Jens Muhlsteff ,  Michael Perkuhn

    IPC分类号： A61B5/02

    CPC分类号： A61B5/6833 ,  A61B5/0002 ,  A61B5/02028 ,  A61B5/02438 ,  A61B5/026 ,  A61B5/0285 ,  A61B5/029 ,  A61B5/721 ,  A61B5/7275 ,  A61B5/7282 ,  G16H50/30

    摘要： The present invention relates to a system (1) and method for detecting and predicting a syncope event. Furthermore the invention relates to a computer program (13) to be executed in a computer (5, 17), said computer (5, 17) being part of a system (1) for detecting and predicting a syncope event. It is an object of the present invention to provide a simple and reliable technique for detecting and predicting the occurrence of syncope events. This object is achieved according to the invention by a method of detecting and predicting a syncope event, the method comprising the steps of continuously obtaining (100) the pulse wave patterns (3) from the upper vascular system of the user (4), determining (101) from the pulse wave patterns (3) a measure (21) of the blood flow to the user's brain, and generating (103) an alarm signal (6), if the blood flow measure indicates the future occurrence of a syncope.

    摘要翻译： 本发明涉及一种用于检测和预测晕厥事件的系统（1）和方法。 此外，本发明涉及要在计算机（5,17）中执行的计算机程序（13），所述计算机（5,17）是用于检测和预测晕厥事件的系统（1）的一部分。 本发明的目的是提供一种用于检测和预测晕厥事件发生的简单可靠的技术。 根据本发明，通过检测和预测晕厥事件的方法来实现本发明的目的，该方法包括以下步骤：从用户（4）的上部血管系统连续地获取（100）脉搏波图形（3），确定 （101）从所述脉搏波形图案（3）到所述用户脑部的血流的测量（21），并且如果所述血流测量指示将来发生晕厥，则产生（103）报警信号（103）。

    Monitoring Device And A Motnitoring Body-Wear
    7.
    发明申请
    Monitoring Device And A Motnitoring Body-Wear 审中-公开
    监控装置和运动身体穿戴

    公开(公告)号：US20080194917A1

    公开(公告)日：2008-08-14

    申请号：US10595876

    申请日：2004-11-24

    申请人： Jens Muehlsteff ,  Harald Reiter ,  Andras Montvay ,  Josef Lauter ,  Olaf Such ,  Ralf Schmidt ,  Michael Perkuhn ,  Fabian Kohler

    发明人： Jens Muehlsteff ,  Harald Reiter ,  Andras Montvay ,  Josef Lauter ,  Olaf Such ,  Ralf Schmidt ,  Michael Perkuhn ,  Fabian Kohler

    IPC分类号： A61B5/00

    CPC分类号： A61B5/6843 ,  A61B5/00

    摘要： A monitoring device (21) arranged to measure a signal (S1) representative of a physiological condition of the individual by means of a suitably arranged sensor (22) and to automatically modify a contact pressure (P) of said sensor meeting real-time requirements. For this purpose the sensor (22) is supported by a piece of elastic material, the monitoring device further comprising an actuator (27) arranged to interact with the piece of elastic material upon receipt of a control signal (CS) from a control unit (25). The control unit (25) is arranged to analyze the signal (S1) from the sensor (22) and to decide on an alteration of the contact pressure (P). For this purpose the control means (25) comprises a logic unit (25a) arranged to carry out a suitable signal analysis. Preferably, the monitoring device (21) is arranged with a further sensor (23), a signal (S3) of which is also provided for analysis to the control unit (25).

    摘要翻译： 一种监视装置（21），其被布置成通过适当布置的传感器（22）来测量代表个人的生理状态的信号（S1），并且自动修改所述传感器的接触压力（P），实时会议 要求。 为此目的，传感器（22）由一块弹性材料支撑，监测装置还包括致动器（27），该致动器被布置为当从控制单元接收到控制信号（CS）时与弹性材料相互作用 25）。 控制单元（25）被布置成分析来自传感器（22）的信号（S 1）并决定接触压力（P）的变化。 为此，控制装置（25）包括布置成执行合适的信号分析的逻辑单元（25a）。 优选地，监视装置（21）布置有另外的传感器（23），其信号（S 3）也被提供给控制单元（25）进行分析。

    Distress signaling system, a body area network for anabling a distress signaling, method for signaling a condition of a distress and a vehicle arranged witha distress signaling system
    8.
    发明申请
    Distress signaling system, a body area network for anabling a distress signaling, method for signaling a condition of a distress and a vehicle arranged witha distress signaling system 审中-公开

    公开(公告)号：US20060290516A1

    公开(公告)日：2006-12-28

    申请号：US10555844

    申请日：2004-04-29

    申请人： Jens Muehlsteff ,  Harald Reiter ,  Andras Montvay ,  Josef Lauter ,  Olaf Such ,  Ralf Schmidt ,  Michael Perkuhn ,  Fabian Kohler

    发明人： Jens Muehlsteff ,  Harald Reiter ,  Andras Montvay ,  Josef Lauter ,  Olaf Such ,  Ralf Schmidt ,  Michael Perkuhn ,  Fabian Kohler

    IPC分类号： G08B23/00

    CPC分类号： B60R21/01534 ,  A61B5/0002 ,  A61B5/024 ,  A61B5/0265 ,  A61B5/0816 ,  A61B5/113 ,  A61B5/18 ,  B60H1/00742 ,  B60H1/00985 ,  B60Q1/52 ,  B60R22/00 ,  G08B21/06

    摘要： The invention relates to a distress signaling system, a body area network for enabling a distress signaling, a method for signaling a condition of a distress and a vehicle arranged with the distress signaling system. The distress signaling system 10 according to the invention comprises monitoring means 11 arranged in a vehicle in order to monitor a vital sign of a seated passenger by means of a sensor 12 arranged to measure a signal representative to said sign. The monitoring means 11 are preferably arranged to perform a continuous monitoring of the vital sign of the passenger and are further arranged to provide a corresponding signal to the front-end electronics 20 of the system 10. The front-end electronics 20 is arranged to analyze the signal from the monitoring means 11. For that purpose the front-end electronics 20 comprises a data processing means 21 arranged to process the measured signal in order to yield data representative to a condition of the passenger. The data processing means 21 comprises a preamplifier 22, an analogue processing circuit 22 and an ADC unit 23. The data processing means 21 forwards the corresponding data to the data analysis means 25, arranged to analyze said data in order to yield a condition-related parameter. The determined condition-related parameter is written into a first look-up table 25a. The data analysis means 25 is further arranged to compare said condition-related parameter to a preset valid parameter stored in a second look-up table 25b. In case the data analysis means detects that the condition-related parameter exceeds a preset valid parameter, it generates a trigger signal to actuate the indicating means 26. The indicating means 26 receives the trigger signal and generate a suitable feedback to the passenger, preferably by means of a suitable user-interface 27. Additionally, the indicating means 26 can be arranged to control a vehicle control system 29, in order to alter a cabin environment, or to actuate an alarming means of the vehicle, like an acoustic alarm and/or the emergency lights and/or to actuate an engine of the vehicle.