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公开(公告)号：US20150283306A1
公开(公告)日：2015-10-08
申请号：US14678525
申请日：2015-04-03
Applicant: MicroVention, Inc.
Inventor： Michael Constant , Edward Michael Keeley , Joshua Garretson , Gregory M. Cruise , Wendy Graczyk
CPC classification number: A61L31/048 , A61L31/145 , A61L31/18 , A61L2300/102 , A61L2430/36 , C08L33/26 , C08L33/10
Abstract: Described herein are apparatus, compositions, systems and methods for occluding vascular structures and vascular malformations with radiopaque hydrogel filaments. The filaments can contain no support members and can be CT and MR compatible. Methods of forming such filaments are also disclosed.
Abstract translation: 本文描述的是用不透射线水凝胶细丝阻塞血管结构和血管畸形的装置，组合物，系统和方法。 长丝不能含有支撑构件，可以兼容CT和MR。 还公开了形成这种细丝的方法。
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公开(公告)号：US20150190553A1
公开(公告)日：2015-07-09
申请号：US14661995
申请日：2015-03-18
Applicant: MicroVention, Inc.
Inventor： Michael Constant , Edward Michael Keeley , Joshua Garretson , Gregory M. Cruise
CPC classification number: A61L31/048 , A61K9/0019 , A61K9/0024 , A61K47/30 , A61K47/34 , A61K49/0404 , A61K49/126 , A61K51/1213 , A61L31/145 , A61L31/18 , A61L2430/36 , Y10T428/298 , C08L33/26
Abstract: Described herein are apparatus, compositions, systems and methods for occluding vascular structures and vascular malformations with radiopaque hydrogel filaments. The filaments can contain no support members and can be CT and MR compatible. Methods of forming such filaments are also disclosed.
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公开(公告)号：US11331340B2
公开(公告)日：2022-05-17
申请号：US16806936
申请日：2020-03-02
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US20160243157A1
公开(公告)日：2016-08-25
申请号：US15142395
申请日：2016-04-29
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
IPC: A61K31/785 , A61K9/00
CPC classification number: A61K31/785 , A61K9/0024 , A61K31/78 , A61K47/32 , A61L24/0089 , A61L24/046 , A61L2430/36
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US20130243936A1
公开(公告)日：2013-09-19
申请号：US13781385
申请日：2013-02-28
Applicant: MICROVENTION, INC.
Inventor： Joshua Garretson , John Belletto , Gregory M. Cruise
IPC: B05D5/00 , C09D171/08
CPC classification number: B05D5/00 , A61L29/085 , A61L31/10 , A61L2420/02 , B05D3/142 , B05D2503/00 , C08G18/4833 , C08G18/7831 , C09D171/08 , C09D175/08
Abstract: Described herein are methods of coating both metallic and polymeric surfaces adding hydrophilicity comprising the steps mixing a coating composition comprising at least one polyol, at least one compound having at least two isocyanate groups, and an organic solvent; introducing nucleophilic functional groups on the surface thereby creating an active surface; subjecting the active surface to the coating composition thereby forming a coated surface; and curing the coated surface. Medical devices, for example, implantable medical devices can be coated by the methods described herein.
Abstract translation: 本文描述了涂覆亲水性的金属和聚合物表面的方法，包括将包含至少一种多元醇，至少一种具有至少两个异氰酸酯基团的化合物和有机溶剂的涂料组合物混合的步骤; 在表面上引入亲核官能团从而产生活性表面; 使活性表面经受涂层组合物从而形成涂覆表面; 并固化涂层表面。 可以通过本文所述的方法来涂覆医疗装置，例如可植入医疗装置。
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Patent Agency Ranking
公开(公告)号：US20200268789A1
公开(公告)日：2020-08-27
申请号：US16806936
申请日：2020-03-02
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
IPC: A61K31/785 , A61K9/00 , A61K31/78 , A61L24/00 , A61L24/04
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US10124090B2
公开(公告)日：2018-11-13
申请号：US14678525
申请日：2015-04-03
Applicant: MicroVention, Inc.
Inventor： Michael Constant , Edward Michael Keeley , Joshua Garretson , Gregory M. Cruise , Wendy Graczyk
Abstract: Described herein are apparatus, compositions, systems and methods for occluding vascular structures and vascular malformations with radiopaque hydrogel filaments. The filaments can contain no support members and can be CT and MR compatible. Methods of forming such filaments are also disclosed.
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公开(公告)号：US10201562B2
公开(公告)日：2019-02-12
申请号：US15924028
申请日：2018-03-16
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US20180200288A1
公开(公告)日：2018-07-19
申请号：US15924028
申请日：2018-03-16
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
CPC classification number: A61K31/785 , A61K9/0024 , A61K31/78 , A61K47/32 , A61L24/0089 , A61L24/046 , A61L2430/36
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US09381278B2
公开(公告)日：2016-07-05
申请号：US14661995
申请日：2015-03-18
Applicant: MicroVention, Inc.
Inventor： Michael Constant , Edward Michael Keeley , Joshua Garretson , Gregory M. Cruise
IPC: A61K9/00 , A61L31/04 , A61K49/04 , A61K49/12 , A61L31/14 , A61L31/18 , A61K47/34 , A61K47/30 , A61K51/12
CPC classification number: A61L31/048 , A61K9/0019 , A61K9/0024 , A61K47/30 , A61K47/34 , A61K49/0404 , A61K49/126 , A61K51/1213 , A61L31/145 , A61L31/18 , A61L2430/36 , Y10T428/298 , C08L33/26
Abstract: Described herein are apparatus, compositions, systems and methods for occluding vascular structures and vascular malformations with radiopaque hydrogel filaments. The filaments can contain no support members and can be CT and MR compatible. Methods of forming such filaments are also disclosed.
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