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公开(公告)号：US20230026108A1
公开(公告)日：2023-01-26
申请号：US17783839
申请日：2020-12-10
Applicant: S.D. SIGHT DIAGNOSTICS LTD
Inventor： Amir ZAIT , Dan GLUCK , Arnon HOURI YAFIN , David BRAILOVSKY , Yochay Shlomo ESHEL , Sarah LEVY , Joseph Joel POLLAK
Abstract: Apparatus and methods are described including analyzing one or more microscopic images of the blood sample using a machine-learning classifier. An entity within the one or more microscopic images is identified using a first classification model, and a first estimated concentration of the entity within the sample is determined, based upon the entity as identified using the first classification model. The entity is identified within the one or more microscopic images using a second classification model, and a second estimated concentration of the entity within the sample is determined, based upon the entity as identified using the second classification model. The first and second estimated concentrations are compared to each other, and, in response to the comparison, a hybrid classification model that is a hybrid of the first and second classification models is used. Other applications are also described.
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Patent Agency Ranking
公开(公告)号：US20250067968A1
公开(公告)日：2025-02-27
申请号：US18940926
申请日：2024-11-08
Applicant: S.D. Sight Diagnostics Ltd.
Inventor： Yonatan HALPERIN , Dan GLUCK , Noam YORAV-RAPHAEL , Yochay Shlomo ESHEL , Sarah LEVY , Joseph Joel POLLAK
Abstract: Apparatus and methods are described for use with a blood sample and a display, including acquiring a plurality of images of a microscopic imaging field of the blood sample, each of the images being acquired using respective, different imaging conditions. An artificial color microscopic display image of the microscopic imaging field is generated having a similar appearance to that of a color smear image, by mapping the plurality of images to respective channels of the artificial color microscopic display image. A display is driven to display the artificial color microscopic display image of the microscopic imaging field to a user. Other applications are also described.
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公开(公告)号：US20220299436A1
公开(公告)日：2022-09-22
申请号：US17836561
申请日：2022-06-09
Applicant: S.D. Sight Diagnostics Ltd.
Inventor： Amitai FRANKLIN , Trevor RUGGIERO , Sarah LEVY , Joseph Joel POLLAK , Aidan John CARROLL , Sharon PECKER , Yochay Shlomo ESHEL
IPC: G01N21/3577 , G02B21/36 , G02B21/02 , G01N21/31
Abstract: Apparatus and methods are described for use with a microscopy unit that comprises an objective lens and a microscope camera. A cantilever includes an objective lens housing. A motor moves the cantilever along a direction of the optical axis of the objective lens. The cantilever is configured, during the movement of the cantilever, to support the objective lens within the objective lens housing such that an optical axis of the objective lens is aligned with the camera, without the objective lens being directly connected to the camera. Other applications are also described.
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公开(公告)号：US20230028360A1
公开(公告)日：2023-01-26
申请号：US17783924
申请日：2020-12-10
Applicant: S.D. Sight Diagnostics Ltd.
Inventor： Yonatan HALPERIN , Dan GLUCK , Noam YORAV-RAPHAEL , Yochay Shlomo ESHEL , Sarah LEVY , Joseph Joel POLLAK
Abstract: Apparatus and methods are described for use with a blood sample. Using a microscope (24), three images of a microscopic imaging field of the blood sample are acquired, each of the images being acquired using respective, different imaging conditions, and the first one of the three images being acquired under violet-light brightfield imaging. Using at least one computer processor (28), an artificial color microscopic image of the microscopic imaging field is generated, by mapping the first one of the three images to a red channel of the artificial color microscopic image, mapping a second one of the three images to a second color channel of the artificial color microscopic image, and mapping a third one of the three images to a third color channel of the artificial color microscopic image. Other applications are also described.
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公开(公告)号：US20230011382A1
公开(公告)日：2023-01-12
申请号：US17783831
申请日：2020-12-10
Applicant: S.D. Sight Diagnostics Ltd.
Inventor： Dan GLUCK , Amir ZAIT , Arnon HOURI YAFIN , Yonatan HALPERIN , Yochay Shlomo ESHEL , Sarah LEVY , Joseph Joel POLLAK , Sharon PECKER , Peretz YAFIN , Dana BENBASSAT , David BRAILOVSKY , Uriyah PUMERANTZ
Abstract: Apparatus and methods are described use with a bodily sample that contains cells. A microscope (24) is focused, such that a focal plane of the microscope (24) at least approximately coincides with a level at which at least some cells belonging to the sample are at least partially disposed. At least one on-focus microscopic image of the sample, while the focal plane of the microscope (24) approximately coincides with the level. The microscope (24) is focused such that the focal plane of the microscope is offset with respect to the level, at least one off-focus microscopic image of the sample is acquired, while the focal plane of the microscope (24) is offset with respect to the level. A property of at least a portion of the sample is determined, at least partially based upon the on-focus and off-focus images. Other applications are also described.
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公开(公告)号：US20230003622A1
公开(公告)日：2023-01-05
申请号：US17783930
申请日：2020-12-10
Applicant: S.D. SIGHT DIAGNOSTICS LTD
Inventor： Peretz YAFIN , Dan GLUCK , Amir ZAIT , Yochay Shlomo ESHEL , Sarah LEVY , Joseph Joel POLLAK
Abstract: Apparatus and methods are provided including imaging a blood sample that is a cell suspension deposited in a sample chamber. The cells are allowed to settle in the sample chamber to form a monolayer of cells. At least one microscopic image is acquired of the monolayer of cells using a microscope (24) while the microscope is focused at a monolayer-depth-level, and a first platelet count of platelets that have settled within the monolayer, is determined. An additional microscopic image of the simple is acquired, while the microscope is focused at a different depth level from the monolayer-depth-level, and a second platelet count of platelets that have not settled within the monolayer is determined. An output is generated based upon the first and second platelet counts. Other applications are also described.
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