公开(公告)号：US20210140825A1

公开(公告)日：2021-05-13

申请号：US17135675

申请日：2020-12-28

Applicant: SPECLIPSE, Inc.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: G01J3/443

Abstract: Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.

公开(公告)号：US20190053711A1

公开(公告)日：2019-02-21

申请号：US16161335

申请日：2018-10-16

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: A61B5/00 ,  G01J3/02

Abstract: According to an embodiment, a tip for a diagnosis laser handpiece, coupled to a handpiece and used therein includes: a light emission module configured to emit a laser to a target; and a light adjustment module disposed on a path through which the laser emitted to the target travels. The light adjustment module is configured to adjust energy of the laser emitted to the target, and a focus size of the laser.

公开(公告)号：US20180206780A1

公开(公告)日：2018-07-26

申请号：US15895509

申请日：2018-02-13

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: A61B5/00

CPC classification number: A61B5/444 ,  A61B5/0095 ,  A61B5/7435 ,  A61N5/0616

Abstract: According to one embodiment of the present disclosure, a device for diagnosing a pigmented lesion includes: a sound detector configured to detect a photoacoustic wave generated when a laser is irradiated onto a target from which a pigmented lesion is to be identified; and a diagnosis unit configured to calculate a depth and/or thickness of the pigmented lesion, based on a time at which the photoacoustic wave is detected, and laser irradiation time information on the laser irradiated onto the target.

公开(公告)号：US20240013394A1

公开(公告)日：2024-01-11

申请号：US18065832

申请日：2022-12-14

Applicant: SPECLIPSE, INC

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: G06T7/00 ,  G06N3/04

CPC classification number: G06T7/0014 ,  G06N3/04 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30088 ,  G06T2207/30096 ,  G06T2207/30196

Abstract: Provided is a disease information providing method including obtaining first image data obtained by image-capturing a body part and one or more suspicious tissues located in the body part, analyzing the first image data using an artificial neural network, detecting at least one target tissue from among the one or more suspicious tissues included in the first image data on the basis of the analysis result, requesting second image data on the at least one target tissue, obtaining the second image data obtained by image-capturing the at least one target tissue, obtaining disease information, wherein the second artificial neural network is trained to obtain a target result value related to the plurality of disease indicators for the target tissue included in the image data, and providing a disease score on the basis of the target result value.

公开(公告)号：US20230236181A1

公开(公告)日：2023-07-27

申请号：US17702898

申请日：2022-03-24

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: G01N33/543 ,  B01L3/00 ,  G01N21/65 ,  B01D21/26 ,  B01D21/28 ,  B01D21/00

CPC classification number: G01N33/54373 ,  B01D21/0018 ,  B01D21/265 ,  B01D21/283 ,  B01L3/502753 ,  G01N21/658 ,  B01L2200/0647 ,  B01L2300/087 ,  B01L2300/0654 ,  B01L2300/0681 ,  B01L2300/0883 ,  G01N2201/06113

Abstract: A liquid refining apparatus is disclosed. The liquid refining apparatus includes a substrate, a loader which is formed on the substrate and configured to receive a first liquid, a filter which is configured to reduce a concentration of at least one substance contained in the first liquid to obtain a second liquid with a reduced concentration of the at least one substance, a reactor which is configured to mix the second liquid with a reactant for target substance detection to obtain a third liquid containing, among a plurality of substances contained in the second liquid, a first substance which undergoes a predetermined reaction with the reactant and a second substance which does not undergo the predetermined reaction with the reactant, and a separator which is configured to separate the first substance and the second substance.

公开(公告)号：US20180098726A1

公开(公告)日：2018-04-12

申请号：US15540364

申请日：2017-04-04

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: A61B5/00 ,  A61N5/06 ,  A61B18/20

CPC classification number: A61B5/441 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0082 ,  A61B5/4836 ,  A61B18/203 ,  A61B2017/00061 ,  A61B2018/00452 ,  A61B2018/00785 ,  A61N5/0616 ,  A61N2005/0626 ,  A61N2005/067

Abstract: An aesthetic or medical laser system is disclosed. The laser system includes: a spectrometer configured to measure a spectrum of light which is generated when body tissue is irradiated with a laser for beauty or medical care; a spectrum data comparison unit configured to compare the spectrum of the generated light measured by the spectrometer and a disease diagnosis reference spectrum data DB; and a disease diagnosis unit configured to determine whether there exists a disease in the body tissue based on a result of comparing by the spectrum data comparison unit.

公开(公告)号：US20180085004A1

公开(公告)日：2018-03-29

申请号：US15540366

申请日：2017-04-04

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: A61B5/00 ,  A61B5/103

CPC classification number: A61B5/0095 ,  A61B5/1032 ,  A61B5/1075 ,  A61B5/444 ,  A61B5/4887 ,  A61B5/7278

Abstract: According to one embodiment, a system for diagnosing a pigmented lesion is provided. The system includes: a sound detector configured to detect a photoacoustic wave which is generated when a first laser is irradiated onto a target having a pigmented lesion; a disease diagnosis unit configured to determine a type of the pigmented lesion based on generated light which is generated when a second laser is irradiated onto the target; and a pigmented lesion diagnosis unit configured to calculate at least one of a depth and a thickness of the pigmented lesion based on a time at which the photoacoustic wave is detected and laser irradiation time information on the first laser irradiated onto the target.

公开(公告)号：US20240219383A1

公开(公告)日：2024-07-04

申请号：US18113108

申请日：2023-02-23

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN ,  Chang Su JEON ,  In Su KIM ,  Eun Yeong SONG

IPC: G01N33/543 ,  G01N33/58

CPC classification number: G01N33/54373 ,  G01N33/588 ,  G01N2470/06

Abstract: A method of measuring a concentration of an analyte in a bodily fluid sample is provided. The method includes introducing the bodily fluid sample containing the analyte into a test strip for a lateral flow assay (LFA) by a first volume to react the analyte with a metal nano probe for surface-enhanced Raman scattering (SERS), introducing a washing liquid into the test strip by a second volume after a first predetermined time interval has elapsed from the introduction of the bodily fluid sample, and performing a surface-enhanced Raman scattering (SERS)-based spectroscopic analysis on at least one of a test area and a control area of the test strip using a spectroscopic device.

公开(公告)号：US20230285077A1

公开(公告)日：2023-09-14

申请号：US17617793

申请日：2021-11-11

Applicant: SPECLIPSE INC

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: A61B18/20 ,  A61B18/04

CPC classification number: A61B18/203 ,  A61B18/042 ,  A61B2018/00452

Abstract: A laser irradiation device includes a housing which has an accommodation space formed therein and an opening formed in one side thereof, a laser module which is positioned in the accommodation space and outputs a pulsed beam having a predetermined focal length and a predetermined focal depth range through the opening, a guide member positioned at one side of the housing, and a contact member which is mounted on the guide member and includes a contact portion having a through-hole, through which the pulsed beam passes, formed therein, wherein the contact portion is in contact with a subject to assist in fixing an irradiation point of the pulsed beam, one end of the contact portion is positioned within the focal depth range such that plasma ablation is induced in at least a portion of the subject, and a diameter of the through-hole having a circular shape.

公开(公告)号：US20230234054A1

公开(公告)日：2023-07-27

申请号：US17702888

申请日：2022-03-24

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: B01L3/00

CPC classification number: B01L3/502753 ,  B01L2300/0816 ,  B01L2300/0681

Abstract: A fluid separation apparatus is disclosed. The fluid separation apparatus includes a diluter which includes a first filter channel through which a fluid flows, a fluid structure formed to protrude outward from the first filter channel and including an air bag, and a first vibration generator configured to generate a first sound wave and which is configured to filter at least one substance included in the fluid based on a vortex of the fluid formed on an interface between the first filter channel and the air bag, and a separator which includes a second filter channel through which the diluted fluid flows, a second vibration generator configured to generate a second sound wave passing through the second filter channel, and a plurality of outlet channels branched from the second filter channel, wherein a plurality of substances included in the diluted fluid are separated based on the molecular weight.