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    Sample multiprocessing
    3.
    发明授权
    Sample multiprocessing 有权
    示例多处理

    公开(公告)号：US07785535B2

    公开(公告)日：2010-08-31

    申请号：US11570184

    申请日：2005-06-07

    申请人： Shuqi Chen ,  Bertrand Lemieux ,  Lingjun Chen

    发明人： Shuqi Chen ,  Bertrand Lemieux ,  Lingjun Chen

    IPC分类号： G01N21/00 ,  G01N31/00 ,  G01N33/00

    CPC分类号： B01L3/502 ,  B01L3/505 ,  B01L7/52 ,  B01L2200/0647 ,  B01L2200/10 ,  B01L2300/0681 ,  B01L2300/0809 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/123 ,  B01L2400/0481 ,  B01L2400/0683 ,  Y10T436/25

    摘要： A sample processing cartridge may include a plurality of segments arranged in an array at least two rows long and two columns wide. Each segment may be defined by at least one wall of the sample cartridge, fluidly isolated from adjacent segments at least in part by at least one breakable seal or by at least one permanent seal, so expandable as to receive a volume of fluid expelled from another segment, and so compressible as to contain substantially no fluid when so compressed. At least two adjacent segments of at least one row of the array may be aligned along a longitudinal axis of the row and have substantially the same height along a latitudinal axis of the row. At least two adjacent segments in at least one row may be separated by a permanent seal to form at least two tracks. At least one segment, or at least two adjacent segments separated by a breakable seal, may be in fluid communication with the at least two tracks. At least one segment may contain at least one reagent.

    摘要翻译： 样品处理盒可以包括以至少两行长和两列宽排列成阵列的多个片段。 每个段可以由样品盒的至少一个壁限定，至少部分地由相邻节段隔离，至少一个可破坏的密封件或通过至少一个永久性密封件，该密封件可膨胀以接收从另一个排出的一定体积的流体 片段，并且如此可压缩，以便在被压缩时基本上不含流体。 阵列的至少一排的至少两个相邻的段可以沿着该行的纵向轴线对准，并且沿着行的纬度轴线具有基本上相同的高度。 至少一行中的至少两个相邻的区段可以通过永久密封件分开以形成至少两个轨道。 由可破坏的密封件分开的至少一个段或至少两个相邻的段可以与至少两个轨道流体连通。 至少一个片段可以含有至少一种试剂。

    Sample Multiprocessing
    5.
    发明申请
    Sample Multiprocessing 有权
    样品多重处理

    公开(公告)号：US20070292858A1

    公开(公告)日：2007-12-20

    申请号：US11570184

    申请日：2005-06-07

    申请人： Shuqi Chen ,  Bertrand Lemieux ,  Lingjun Chen

    发明人： Shuqi Chen ,  Bertrand Lemieux ,  Lingjun Chen

    IPC分类号： C12Q1/68 ,  B01J19/00 ,  C12M1/34 ,  C12Q1/00

    CPC分类号： B01L3/502 ,  B01L3/505 ,  B01L7/52 ,  B01L2200/0647 ,  B01L2200/10 ,  B01L2300/0681 ,  B01L2300/0809 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/123 ,  B01L2400/0481 ,  B01L2400/0683 ,  Y10T436/25

    摘要： A sample processing cartridge may include a plurality of segments arranged in an array at least two rows long and two columns wide. Each segment may be defined by at least one wall of the sample cartridge, fluidly isolated from adjacent segments at least in part by at least one breakable seal or by at least one permanent seal, so expandable as to receive a volume of fluid expelled from another segment, and so compressible as to contain substantially no fluid when so compressed. At least two adjacent segments of at least one row of the array may be aligned along a longitudinal axis of the row and have substantially the same height along a latitudinal axis of the row. At least two adjacent segments in at least one row may be separated by a permanent seal to form at least two tracks. At least one segment, or at least two adjacent segments separated by a breakable seal, may be in fluid communication with the at least two tracks. At least one segment may contain at least one reagent.

    摘要翻译： 样品处理盒可以包括以至少两行长和两列宽排列成阵列的多个片段。 每个段可以由样品盒的至少一个壁限定，至少部分地由相邻节段隔离，至少一个可破坏的密封件或通过至少一个永久性密封件，该密封件可膨胀以接收从另一个排出的一定体积的流体 片段，并且如此可压缩，以便在被压缩时基本上不含有流体。 阵列的至少一排的至少两个相邻的段可以沿着该行的纵向轴线对准，并且沿着行的纬度轴线具有基本上相同的高度。 至少一行中的至少两个相邻的区段可以通过永久密封件分开以形成至少两个轨道。 由可破坏的密封件分开的至少一个段或至少两个相邻的段可以与至少两个轨道流体连通。 至少一个片段可以含有至少一种试剂。

    Method of oral transmucosal delivery of a therapeutic agent
    6.
    发明授权
    Method of oral transmucosal delivery of a therapeutic agent 失效
    口服经粘膜递送治疗剂的方法

    公开(公告)号：US06896519B2

    公开(公告)日：2005-05-24

    申请号：US10229365

    申请日：2002-08-27

    申请人： Lingjun Chen ,  Shuqi Chen

    发明人： Lingjun Chen ,  Shuqi Chen

    IPC分类号： A61C15/00 ,  A61C17/02 ,  A61C19/06 ,  A61C5/00

    CPC分类号： A61C17/0211 ,  A61C15/00 ,  A61C17/0208 ,  A61C19/063

    摘要： A mouthpad for cleaning teeth and oral transmucosal drug delivery has a U-shaped plate sized to cover substantially only the biting surfaces of upper and lower teeth of a human jaw. The plate is positioned between the upper teeth and lower teeth such that when the teeth are rinsed with a liquid, the liquid flows primarily through the crevices between individual teeth and physically detaches the adhering residue within. Alternatively, using fluids containing drugs for rinsing while biting on the plate can deliver drugs through the oral mucosa. A method of cleaning teeth and delivering drugs through oral mucosa using a plate positioned between the upper and lower teeth is also disclosed.

    摘要翻译： 用于清洁牙齿和口腔经粘膜药物递送的口垫具有U形板，其大小仅基本上仅覆盖人颚的上齿和下牙的咬合表面。 板被定位在上齿和下齿之间，使得当牙齿用液体漂洗时，液体主要流过各个齿之间的缝隙并物理地分离粘附的残留物。 或者，使用含有用于冲洗的药物的流体在咬在板上时可以通过口腔粘膜递送药物。 还公开了一种通过使用位于上下牙之间的板来清洁牙齿并通过口腔粘膜输送药物的方法。

    SAMPLE PROCESSING
    9.
    发明申请
    SAMPLE PROCESSING 审中-公开
    样品加工

    公开(公告)号：US20080003564A1

    公开(公告)日：2008-01-03

    申请号：US11674117

    申请日：2007-02-12

    申请人： Shuqi Chen ,  Lingjun Chen

    发明人： Shuqi Chen ,  Lingjun Chen

    IPC分类号： C12Q1/70 ,  C12M1/00 ,  C12Q1/68

    CPC分类号： B01L3/502 ,  B01L3/5029 ,  B01L7/525 ,  B01L2200/0668 ,  B01L2200/10 ,  B01L2300/087 ,  B01L2400/0481 ,  B01L2400/0655

    摘要： A sample processing tubule may include at least three segments. Each segment may be defined by the tubule, may be fluidly isolated, at least in part by a breakable seal, may be so expandable as to receive a volume of fluid expelled from another segment, and may be so compressible as to contain substantially no fluid when so compressed. At least one segment may contain at least a control reagent. At least one segment may contain at least one of a nucleic acid amplification reagent and a detection reagent.

    摘要翻译： 样品处理小管可以包括至少三个片段。 每个段可以由小管限定，至少部分地通过可破坏的密封件被流体隔离，可以是如此可扩张的，以便接收从另一个部分排出的体积的体积，并且可以是如此可压缩的，从而基本上不含流体 当这样压缩。 至少一个片段可以含有至少一种对照试剂。 至少一个区段可以含有核酸扩增试剂和检测试剂中的至少一个。

    SAMPLE PROCESSING METHODS
    10.
    发明申请
    SAMPLE PROCESSING METHODS 有权
    样品加工方法

    公开(公告)号：US20100218621A1

    公开(公告)日：2010-09-02

    申请号：US12782354

    申请日：2010-05-18

    申请人： Shuqi Chen ,  Lingjun Chen

    发明人： Shuqi Chen ,  Lingjun Chen

    IPC分类号： G01N1/10

    CPC分类号： C12N15/1003 ,  B01L3/502 ,  B01L3/505 ,  B01L2200/0621 ,  B01L2200/10 ,  B01L2300/042 ,  B01L2300/046 ,  B01L2300/047 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/087 ,  B01L2300/10 ,  B01L2400/0481 ,  B01L2400/0677 ,  G01N1/10 ,  G01N33/543 ,  Y02A50/52 ,  Y02A50/53 ,  Y02A50/55 ,  Y02A50/58 ,  Y02A50/60 ,  Y10S435/81 ,  Y10T436/25

    摘要： A method of processing a sample may include introducing a sample into a vessel, the vessel having proximal and distal ends, the sample being introduced into the proximal end of the vessel; incubating the sample in the vessel with a substance capable of specific binding to a preselected component of the sample; propelling components of the incubated sample, other than the preselected component, toward the proximal end of the vessel by clamping the vessel distal to the incubated sample and compressing the vessel where the incubated sample is contained; propelling the preselected component toward a distal segment of the vessel by clamping the vessel proximal to the preselected component and compressing the vessel where the preselected component is contained; and mixing the preselected component with a reagent in the distal segment of the vessel.

    摘要翻译： 处理样品的方法可以包括将样品引入容器中，所述容器具有近端和远端，样品被引入容器的近端; 将样品在容器中用能够与样品的预选组分特异性结合的物质进行孵育; 将孵育的样品（除了预选组分之外）的组分通过将血管夹紧在孵育样品的远端并压缩容纳培养的样品的容器，向容器的近端推进; 通过将血管夹紧在预选组件附近并压缩容纳预选组分的血管，将预选组分推向血管的远侧段; 并将预选组分与血管远端段中的试剂混合。