摘要:
A compound represented by the formula (I): (R1)m-AnullXY-Bnull(R2)nnullnull(I) or a salt or a solvate thereof; and a composition and a kit both containing any of these. In said formula I, X represents CH, Sulfur, or nitrogen; Y represents CH, sulfur or nitrogen, or absent; means a single bond or a double bond; A and B each independently represents a benzene ring or six-membered heterocyclic containing one or two atoms of nitrogen, oxygen, or sulfur; and R1 and R2 represent one to seven substituents of ring A and ring B, respectively.
摘要:
The present invention relates to transition-metal-free process for the synthesis of tertiary arylamines comprises coupling reaction between arynes and N,N-dimethyl aniline compounds in presence of 18-crown-6, KF and THF.
摘要:
The present invention relates to novel processes for the preparation of substituted tetralin and substituted indane derivatives. The present invention is further directed to novel processes for the preparation of intermediates in the preparation of the substituted tetralin and substituted indane derivatives.
摘要:
The present invention is directed to processes for the synthesis of intermediates useful in the preparation of non-nucleoside reverse transcriptase inhibitors.
摘要:
The invention relates to a process for the preparation of diazonaphthoquinonesulfonylchlorides of the formula 1, 2 and 3 using diphosgene or triphosgene.
摘要:
A novel benzenesulfonamide derivative represented by the formula: ##STR1## has an inhibitory activity against phospholipase A.sub.2, so that it is effective in the treatment of diseases for which such an activity is efficacious.
摘要:
The present invention relates to improved covalent coupling of two or more entities such as biomolecules, polymer compositions, organic/inorganic molecules/materials, and the like, including their combinations, through one or more novel reactive groups attached to linker groups of 2-1000 atoms length. The present invention also contemplates the use of bifunctional bridge molecules to link two or more entities, wherein the functional groups of the bridge molecules are the novel reactive groups of the present invention.