MANIFOLDS, SYSTEMS AND METHODS FOR MEASURING CELL FUNCTIONS

    公开(公告)号:US20240382948A1

    公开(公告)日:2024-11-21

    申请号:US18613776

    申请日:2024-03-22

    Inventor: Jordan Miller

    Abstract: Various embodiments of the present disclosure disclose manifolds, methods, and systems for measuring cell functions. In various embodiments, a first reservoir storing a first fluid and a second reservoir storing a second fluid may be fluidically connected via a fluid channel. Further, the first fluid and the second fluid may be such that an entropic gradient force causes the first fluid to flow towards a container that is located therebetween and contains cells therein. The cells release cell products into the first fluid flowing in the fluidic channel, which in turn flows into the second reservoir. The cell products can be sampled from the second reservoir and/or from the container to measure the function of the cells.

    EFFICIENT BULK UNFUSED POWDER REMOVAL SYSTEM AND METHOD

    公开(公告)号:US20230364681A1

    公开(公告)日:2023-11-16

    申请号:US18163956

    申请日:2023-02-03

    CPC classification number: B22F10/68 B33Y40/20 B22F10/28 B33Y30/00 B33Y10/00

    Abstract: An additive manufacturing system for producing a three-dimensional article includes a print engine, a post-fabrication powder removal apparatus, a transport mechanism, and a controller. The post fabrication removal apparatus includes a rotary frame defining an internal receptacle cavity, a plurality of clamps coupled to a corresponding plurality of actuators, a clamping plate coupled to a lift apparatus, and an agitation device mounted to the clamping plate. The controller is configured to perform the following steps: (1) Operate the transport mechanism to transport the build box to the internal receptacle cavity. (2) Operate the plurality of actuators to engage the build box with the plurality of clamps to secure the build box to the rotary frame. (3) Operate the rotary frame to rotate the build box until unfused powder begins to exit the build box. (4) Operate the agitation device to facilitate pouring of the unfused powder from the build box.

    3D printing system with agitation device

    公开(公告)号:US11813796B2

    公开(公告)日:2023-11-14

    申请号:US17848452

    申请日:2022-06-24

    Abstract: A three-dimensional (3D) printing system is configured to manufacture a three-dimensional 3D article in a layer-by-layer manner. The 3D printing system includes a resin vessel, a tank agitation subsystem, a fabrication subsystem, and a controller. The resin vessel is configured to contain photocurable resin and has a lower region within a distance H of a bottom surface of the resin vessel. The agitation subsystem includes (a) a grating disposed within the lower region of the resin vessel and (b) an agitation movement mechanism coupled to the grating. The fabrication subsystem is configured to form the 3D article by a layer-by-layer selective curing of the photocurable resin. The controller is configured to operate the agitation movement mechanism to oscillate the grating along a lateral Y-axis to remix filler particulates within the photocurable resin.

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