公开(公告)号：US20150305595A1

公开(公告)日：2015-10-29

申请号：US14652155

申请日：2013-12-08

Applicant: GIVEN IMAGING LTD.

Inventor： Semion KHAIT ,  Oren ROSENBERG

IPC: A61B1/00 ,  A61B1/04 ,  H04B5/00

CPC classification number: A61B1/00006 ,  A61B1/00036 ,  A61B1/041 ,  H04B5/0037

Abstract: A control circuit for controlling a state of a switching circuit may include a first unit to sense and interpret a wireless signal or physical parameter as an “on” signal to transition the switching circuit to the “on” state, or as an “off” signal to transition the switching circuit to the “off” state, and to transfer a first digital signal or logic value and/or a second digital signal or logic value, which may respectively or combinatorially represent the “on” signal or the “off” signal, to a second unit via a first output and/or a second output of the first unit, respectively. The second unit may force a control input of the switching circuit to a logic value which is a function of the first digital signal or value and/or second digital signal or value and congruent with the state to which the switching circuit is to be transitioned.

Abstract translation: 用于控制开关电路的状态的控制电路可以包括：第一单元，用于感测和解释无线信号或物理参数作为“开”信号，以将开关电路转换到“接通”状态，或者作为“关” 信号将开关电路转换到“关”状态，并且传送第一数字信号或逻辑值和/或第二数字信号或逻辑值，其可以分别地或组合地表示“接通”信号或“关” 分别经由第一单元的第一输出和/或第二输出向第二单元发送信号。 第二单元可以将开关电路的控制输入强制为与第一数字信号或值和/或第二数字信号或值的函数并且与切换电路要转换的状态一致的逻辑值。

公开(公告)号：US20150148626A1

公开(公告)日：2015-05-28

申请号：US14416064

申请日：2013-07-23

Applicant: GIVEN IMAGING LTD.

Inventor： Osnat Sella-Tavor ,  Elisha Rabinovitz

IPC: A61B5/1459 ,  A61B5/00 ,  A61B5/145

CPC classification number: A61B5/1459 ,  A61B5/0059 ,  A61B5/0071 ,  A61B5/073 ,  A61B5/14507 ,  A61B5/42 ,  A61B5/4848 ,  A61K38/00 ,  C12Q1/6886

Abstract: In-vivo methods and kits for detecting presence of a combination of biomarkers indicating colorectal cancer are described. One of the methods includes inserting into a patient a combination of binding agents comprising one binding agent having high affinity to CEACAM5 and at least one binding agent having high affinity to at least one of two biomarkers selected from Olfactomedin 4- (OLFM4) and S100P. The method further includes inserting into the patient an in-vivo sensing device, detecting an optical change using the in-vivo sensing device, which occurs when at least one of the combination of binding agents binds to at least one of the corresponding combination of biomarkers, and determining, based on the optical change, presence of colorectal cancer in the patient.

Abstract translation: 描述了用于检测指示结肠直肠癌的生物标志物的组合的存在的体内方法和试剂盒。 方法之一包括将包含与CEACAM5具有高亲和力的一种结合剂和至少一种与至少一种选自Olfactomedin 4-（OLFM4）和S100P）的生物标志物的亲和力的结合剂结合在一起的患者。 该方法还包括向患者插入体内感测装置，使用体内感测装置检测光学变化，当粘合剂的组合中的至少一种与至少一个生物标志物的组合结合时发生 ，并且基于光学变化确定患者中结肠直肠癌的存在。

公开(公告)号：US20150016700A1

公开(公告)日：2015-01-15

申请号：US14375318

申请日：2013-01-30

Applicant: GIVEN IMAGING LTD.

Inventor： Michal Drozdzal ,  Santiago Segui Mesquida ,  Petia Radeva ,  Jordi Vitria ,  Laura Igual-Munoz ,  Carolina Malagelada ,  Fernando Azpiroz

IPC: G06T11/60 ,  G06T7/00 ,  G06K9/00

CPC classification number: G06T11/60 ,  A61B1/00009 ,  A61B1/00045 ,  A61B1/041 ,  G06F19/00 ,  G06F19/321 ,  G06K9/00523 ,  G06T7/0016 ,  G06T2207/30028 ,  G06T2207/30092 ,  G16H40/63

Abstract: A system and method may analyse and display intestinal motility events, based on an image stream captured by an in vivo imaging device. According to some embodiments, the system includes a storage unit to store image frames from the image stream, a processor to select a strip of pixels from a plurality of image frames of the image stream and to align the selected strips adjacently to form a motility events bar, and a visual display unit for displaying the motility events bar to a user.

Abstract translation: 系统和方法可以基于由体内成像装置捕获的图像流来分析和显示肠蠕动事件。 根据一些实施例，该系统包括存储单元以存储来自图像流的图像帧，处理器从图像流的多个图像帧中选择像素条，并且相邻地对准所选择的条带以形成运动性事件 酒吧和用于向使用者显示运动事件栏的视觉显示单元。

公开(公告)号：US20140275860A1

公开(公告)日：2014-09-18

申请号：US14212304

申请日：2014-03-14

Applicant: Given Imaging Ltd.

Inventor： Dan ROTTENBERG ,  Robert Sayegh

IPC: A61B5/02 ,  A61B1/06 ,  A61B1/04 ,  A61B5/00 ,  A61B5/07

CPC classification number: A61B5/02042 ,  A61B1/00087 ,  A61B1/041 ,  A61B1/06 ,  A61B5/0084 ,  A61B5/073 ,  A61B5/4233 ,  A61B5/4238 ,  A61B5/4255 ,  A61B2562/162 ,  A61B2562/18

Abstract: Devices and a system for detection of blood within in-vivo fluids are provided. A device comprises a housing that includes a gap. The gap has at least one opening through which in-vivo fluids may enter and/or exit the gap. The device further comprises an illumination source for illuminating the in-vivo fluids in the gap, a light detector for detecting light which passes through the in-vivo fluids in the gap, and flexible fins disposed on the housing in the vicinity of the gap's opening for covering the opening when the fins are folded and for pumping fluids into and out of the opening by repeated closure and opening of the opening by the fins, due to repeated peristaltic waves. This pumping effect may lead to continuous flow of fluids into and out of the opening and thus into and out of the gap of the device.

Abstract translation: 提供了用于检测体内流体内的血液的装置和系统。 一种装置包括包括间隙的壳体。 间隙具有至少一个开口，体内流体可通过该开口进入和/或离开间隙。 该装置还包括用于照射间隙中的体内流体的照明源，用于检测通过间隙中的体内流体的光的光检测器，以及设置在间隙开口附近的壳体上的柔性翅片 用于当翅片被折叠时覆盖开口，并且由于重复的蠕动波，通过由翅片重复地关闭和打开开口来将流体泵入和流出开口。 这种泵送效应可能导致流体连续流入和流出开口，从而进入和流出装置的间隙。

公开(公告)号：US20250000349A1

公开(公告)日：2025-01-02

申请号：US18882079

申请日：2024-09-11

Applicant: Given Imaging LTD.

Inventor： Eyal Dekel ,  Roni Keynan

IPC: A61B1/04 ,  A61B1/00 ,  G06T7/00 ,  G06T7/70

Abstract: Systems, devices, methods for capsule endoscopy procedures are disclosed. A swallowable capsule apparatus includes one or more processors and one or more memory storing instructions. The instructions, when executed by the one or more processors, cause the swallowable capsule apparatus at least to perform: capturing in-vivo images over time of at least a portion of a gastrointestinal tract (GIT) of a person; pruning, over time, at least a portion of the in-vivo images; and communicating images of the in-vivo images, which were not pruned, to a receiver device external to the person.

公开(公告)号：USD1026471S1

公开(公告)日：2024-05-14

申请号：US29832386

申请日：2022-03-28

Applicant: Given Imaging LTD

Designer： Eyal David ,  Eli Ziv

Abstract: FIG. 1 is a perspective view of blister packaging for a medical patch in accordance with the present design;
FIG. 2 is another perspective view of the blister packaging for a medical patch of FIG. 1;
FIG. 3 is a rear elevational view of the blister packaging for a medical patch of FIG. 1;
FIG. 4 is a front elevational view of the blister packaging for a medical patch of FIG. 1;
FIG. 5 is a left side elevational view of the blister packaging for a medical patch of FIG. 1;
FIG. 6 is a right side elevational view of the blister packaging for a medical patch of FIG. 1;
FIG. 7 is a top plan view of the blister packaging for a medical patch of FIG. 1; and,
FIG. 8 is a bottom plan view of the blister packaging for a medical patch of FIG. 1.
The broken lines immediately adjacent the shaded areas represent the bounds of the claimed design while all other broken lines are included for the purpose of illustrating portions of the blister packaging for a medical patch; the broken lines form no part of the claimed design.

公开(公告)号：US20240138753A1

公开(公告)日：2024-05-02

申请号：US18278986

申请日：2022-03-21

Applicant: Given Imaging LTD

Inventor： Arkadiy Morgenshtein ,  Iddo Diukman ,  Benny Linder ,  Dori Peleg

IPC: A61B5/00 ,  G16H40/67 ,  G16H50/20

CPC classification number: A61B5/4233 ,  A61B5/6847 ,  A61B5/7221 ,  A61B5/7267 ,  A61B5/7282 ,  G16H40/67 ,  G16H50/20

Abstract: A system for diagnosing an esophageal disease includes at least one processor and at least one memory storing instructions. The instructions, when executed by the at least one processor, cause the system to: access, during a procedure involving an in-vivo device located within a person, data measured by the in-vivo device relating to an esophageal disease; evaluate, during the procedure while the in-vivo device is located within the person, a diagnosis for the esophageal disease for the person by applying a trained machine learning model to the data measured by the in-vivo device; and communicate, during the procedure while the in-vivo device is located within the person, the diagnosis for the esophageal disease.

公开(公告)号：US20230274422A1

公开(公告)日：2023-08-31

申请号：US18020291

申请日：2021-09-03

Applicant: Given Imaging LTD.

Inventor： Dori Peleg

IPC: G06T7/00 ,  G16H30/40 ,  G16H50/20

CPC classification number: G06T7/0012 ,  G16H30/40 ,  G16H50/20 ,  G06T2207/10068 ,  G06T2207/30092 ,  G06T2207/30096 ,  G06T2207/20081 ,  A61B1/041

Abstract: Systems and methods are disclosed for identifying images that contain polyps. An exemplary method for identifying images includes: accessing images of a gastrointestinal tract (GIT) captured by a capsule endoscopy device, where: each image of the images is suspected to include a polyp and is associated with a probability of containing the polyp, and the images include seed images, where each seed image is associated with one or more images of the images. The image(s) associated with each seed image is identified as suspected to include the same polyp as the associated seed image. The method includes applying a polyp detection system on the seed images to identify seed images which include polyps, where the polyp detection system is applied to each seed image of based on the image(s) associated with the seed image and the probabilities associated with the seed image and with the associated image(s).

公开(公告)号：US11602264B2

公开(公告)日：2023-03-14

申请号：US17149066

申请日：2021-01-14

Applicant: GIVEN IMAGING LTD.

Inventor： Dori Peleg

IPC: G06T7/00 ,  A61B1/04 ,  A61B1/00

Abstract: A method executed by a system for selecting images from a plurality of image groups originating from a plurality of imagers of an in-vivo device includes calculating, or otherwise associating, a general score (GS) for images of each image group, to indicate the probability that each image includes at least one pathology, dividing each image group into image subgroups, identifying a set Set(i) of maximum general scores (MGSs), a MGS for each image subgroup of each image group; and selecting images for processing by identifying a MGS|max in each set S(i) of MGSs; identifying the greatest MGS|max and selecting the image related to the greatest MGS|max. The method further includes modifying the set Set(i) of MGSs related to the selected image, and repeating the steps described above until a predetermined criterion selected from a group consisting of a number N of images and a score threshold is met.

公开(公告)号：US11251005B2

公开(公告)日：2022-02-15

申请号：US15710114

申请日：2017-09-20

Applicant: GIVEN IMAGING LTD.

Inventor： Arkadiy Morgenshtein

IPC: H01H47/24 ,  G01J1/44 ,  A61B1/06 ,  A61B1/00 ,  A61B1/04 ,  G01J1/02 ,  G01J1/42

Abstract: An on/off switching circuit includes an on/off switch switchable between an on state and an off state, an light emitting diode (LED) driver to power one or more LEDs to illuminate an area of interest, a switch control unit to transition the on/off switch between the on and off states, the switch control unit including a light sensing circuit comprising at least one LED of the LEDs as a light sensor, and a bi-directional gate circuit. When the on/off switch is in the off state the bi-directional gate is in a first conducting state in which the bi-directional gate circuit connects the light sensor to the light sensing circuit, and when the on/off switch is in the on state the bi-directional gate is in a second conducting state in which the bi-directional gate connects the LED driver to the one or more LEDs including the light sensor.