摘要:
A deposition apparatus and a method for sputtering material on a substrate is provided with a substrate holder for holding the substrate, a rotatable target adapted for being sputtered, and a heating system including a back side heating for heating the substrate from the back and a front side heating for heating the substrate from the front. The rotatable target acts as the front side heating and is adapted for heating the substrate to a temperature of at least 100° C. A method for performing this method is disclosed.
摘要:
Microfluidic nucleic acid hybridization systems are described that include a first reaction chamber to hold an analyte solution comprising nucleic acids, and a first mixing channel in fluid communication with the chamber. The mixing channel includes a textured surface to mix the analyte solution. The systems may also include pump coupled to the mixing channel to circulate the analyte solution through the reaction chamber and the mixing channel, and an input port in fluid communication with the mixing channel and the reaction chamber to supply the analyte solution to the microfluidic system. The input port can be closed to create a closed circulation path for the analyte solution through the reaction chamber and the mixing channel.
摘要:
A sphygmomanometer having an elongated tube, an air chamber coupled to a first end of the tube, and a liquid chamber coupled to a second end of the tube. The liquid chamber is partially filled with fluid and is couplable to a source of external pressure. An offset region located proximate the second end of the tube has a significantly reduced cross-sectional area so as to reduce the effect of fluid level changes on pressure measurement accuracy. At least one ventilation valve is coupled to the elongated tube and the air chamber and is operative to vent the elongated tube and the air chamber to atmosphere.
摘要:
A method of sulfating a polysaccharide is provided. The method can include providing a reaction mixture comprising at least one O-sulfotransferase (OST) enzyme and 3′-phosphoadenosine 5′-phosphosulfate (PAPS); incubating a polysaccharide substrate with the reaction mixture, wherein production of the sulfated polysaccharide from the polysaccharide substrate is catalyzed by the OST enzyme with a conversion of the PAPS to adenosine 3′,5′-diphosphate (PAP); and providing a reaction condition which modifies PAP to reduce an inhibitory effect of PAP on the polysaccharide sulfation.
摘要:
Certain novel N-acylated spiropiperidine derivatives are ligands of the human melanocortin receptor(s) and, in particular, are selective ligands of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of MC-4R, such as obesity, diabetes, nicotine addiction, alcoholism, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.
摘要:
A method for generating a laser projection by employing a laser gain medium for receiving an optical input projection from a laser pump. The method further includes a step of generating a laser of a resonant peak from a single mode selection filter.
摘要:
A fiber Chirped Pulse Amplification (CPA) laser system includes a fiber mode-locking oscillator for generating a laser and stretching into a few hundreds ps-10 ns pulse by a fiber stretcher for projecting into an acoustic-optic (AO) functioning as a pulse picker for generated a modulated laser with a reduced repetition rate for projecting to a multiple stage amplifier. The multiple stage amplifier further includes a first high-energy amplifier implemented with a large mode area (LMA) fiber for amplifying the modulated laser up to a uJ level laser and a second amplifier implemented with a PCF based Yb doped fiber to further amplify the uJ level laser to a mJ level laser.
摘要:
A method for generating a laser projection by employing a laser gain medium for receiving an optical input projection from a laser pump. The method further includes a step of employing a mode selection filter comprising an electro-optical (EO) tunable layer disposed between two parallel reflection plates for generating a laser of a resonant peak.
摘要:
A device and method for calibrating MIMO systems are disclosed. In one aspect, a calibration circuit comprises at least a first and a second input/output port, each arranged for being connected to a different transmitter/receiver pair of a multiple input multiple output (MIMO) system. The circuit further comprises at least a third and a fourth input/output port, each arranged for being connected to a different antenna. The circuit further comprises an attenuator having a first attenuator port and a second attenuator port. The circuit further comprises a first and a second non-reciprocal switch, the first switch being arranged for establishing a connection between the first input/output port and either the third input/output port or the first attenuator port, and the second switch arranged for establishing a connection between the second input/output port and either the fourth input/output port or the second attenuator port.
摘要:
Compositions and methods are disclosed for the treatment of diabetes and related diseases using peptides with incretin hormone activity. Preferably, the peptide with incretin hormone activity is GLP-1, exendin or an analog of GLP-1 or exendin. The peptides with incretin hormone activity are administered transepithelially using a transepithelial carrier peptide. The transepithelial peptide contains sufficient amino, guanidine or amidino groups to stimulate transepithelial delivery. In some embodiments, the transepithelial carrier and the peptide with incretin hormone activity are embedded in a pressure sensitive adhesive layer of a plaster or patch.