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公开(公告)号:US5849528A
公开(公告)日:1998-12-15
申请号:US918727
申请日:1997-08-21
申请人: Jennifer L. Hillman , Olga Bandman , Neil C. Corley , Preeti Lal , Purvi Shah
发明人: Jennifer L. Hillman , Olga Bandman , Neil C. Corley , Preeti Lal , Purvi Shah
CPC分类号: C07K14/4728 , A61K38/00
摘要: The invention provides two human S100 proteins designated individually as S100P1 and S100P2 and collectively as S100P, and polynucleotides which identify and encode S100P. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of S100P.
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公开(公告)号:US08043818B2
公开(公告)日:2011-10-25
申请号:US11045577
申请日:2005-01-27
申请人: Olga Bandman , Jennifer Hillman , Henry Yue , Karl J. Guegler , Neil C. Corley , Y. Tom Tang , Purvi Shah
发明人: Olga Bandman , Jennifer Hillman , Henry Yue , Karl J. Guegler , Neil C. Corley , Y. Tom Tang , Purvi Shah
IPC分类号: G01N33/53
CPC分类号: C12N9/6424 , A61K38/00 , C07K16/40 , C12N9/48 , C12N9/6472 , C12N9/6478
摘要: The invention provides human protease molecules (HUPM) and polynucleotides which identify and encode HUPM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HUPM.
摘要翻译: 本发明提供了人类蛋白酶分子(HUPM)和识别和编码HUPM的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与HUPM表达相关的病症的方法。
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公开(公告)号:US06030801A
公开(公告)日:2000-02-29
申请号:US295068
申请日:1999-04-20
申请人: Olga Bandman , Neil C. Corley , Karl J. Guegler , Mariah Baughn
发明人: Olga Bandman , Neil C. Corley , Karl J. Guegler , Mariah Baughn
IPC分类号: C12N15/09 , A61K38/00 , A61K38/45 , A61K45/00 , A61P15/00 , A61P35/00 , A61P37/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N15/54 , C12Q1/68 , C12Q1/48 , C12Q1/00 , G01N33/53
CPC分类号: C12N9/1205 , A61K38/00
摘要: The invention provides a human Nek 1-related protein kinase (NRPK) and polynucleotides which identify and encode NRPK. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of NRPK.
摘要翻译: 本发明提供了人Nek1-相关蛋白激酶(NRPK)和识别和编码NRPK的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与NRPK表达相关的紊乱的方法。
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公开(公告)号:US5989859A
公开(公告)日:1999-11-23
申请号:US967364
申请日:1997-11-07
申请人: Olga Bandman , Preeti Lal , Karl J. Guegler , Purvi Shah , Neil C. Corley
发明人: Olga Bandman , Preeti Lal , Karl J. Guegler , Purvi Shah , Neil C. Corley
CPC分类号: C07K14/4701 , A61K38/00
摘要: The invention provides three human vesicle trafficking proteins (VTP) and polynucleotides which identify and encode VTP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of VTP.
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公开(公告)号:US5888792A
公开(公告)日:1999-03-30
申请号:US892256
申请日:1997-07-11
申请人: Olga Bandman , Karl J. Guegler , Neil C. Corley , Purvi Shah
发明人: Olga Bandman , Karl J. Guegler , Neil C. Corley , Purvi Shah
摘要: The invention provides a human ATP-dependent RNA helicase (ADRH-1) and polynucleotides which identify and encode ADRH-1. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of ADRH-1.
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公开(公告)号:US06645499B1
公开(公告)日:2003-11-11
申请号:US09387811
申请日:1999-09-01
申请人: Preeti Lal , Karl J. Guegler , Neil C. Corley
发明人: Preeti Lal , Karl J. Guegler , Neil C. Corley
IPC分类号: A61K3900
CPC分类号: C07K14/4702 , Y10S530/849 , Y10T436/143333
摘要: The invention provides a human ena/VASP-like protein splice variant (EVL1) and polynucleotides which identify and encode EVL1. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of EVL1.
摘要翻译: 本发明提供了鉴定和编码EVL1的人类ena / VASP样蛋白剪接变体(EVL1)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与EVL1表达相关的病症的方法。
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公开(公告)号:US06248594B1
公开(公告)日:2001-06-19
申请号:US09467946
申请日:1999-12-21
IPC分类号: C07K100
CPC分类号: C07K14/47
摘要: The invention provides a human kinesin-like motor protein (KLIMP) and polynucleotides which identify and encode KLIMP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of KLIMP.
摘要翻译: 本发明提供了一种人驱动蛋白样运动蛋白(KLIMP)和识别和编码KLIMP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与KLIMP表达相关的紊乱的方法。
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公开(公告)号:US5994097A
公开(公告)日:1999-11-30
申请号:US919624
申请日:1997-08-28
申请人: Preeti Lal , Karl J. Guegler , Purvi Shah , Neil C. Corley
发明人: Preeti Lal , Karl J. Guegler , Purvi Shah , Neil C. Corley
IPC分类号: C12N15/09 , A61K38/00 , C07K14/705 , C07K16/28 , C12N1/21 , C12N15/12 , C12Q1/68 , C07K14/71 , C12N15/63
CPC分类号: C07K14/705 , A61K38/00 , C12N2799/026
摘要: The invention provides a human G-protein coupled receptor (GRecH) and polynucleotides which identify and encode GRecH. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of GRecH.
摘要翻译: 本发明提供了人G-蛋白偶联受体(GRecH)和识别并编码GRecH的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与GRecH表达相关的疾病的方法。
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公开(公告)号:US5989863A
公开(公告)日:1999-11-23
申请号:US172977
申请日:1998-10-14
申请人: Y. Tom Tang , Karl J. Guegler , Neil C. Corley , Henry Yue
发明人: Y. Tom Tang , Karl J. Guegler , Neil C. Corley , Henry Yue
IPC分类号: G01N33/50 , A61K38/00 , A61K45/00 , A61P29/00 , A61P37/02 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C12P21/06 , C07H21/02 , C12N1/20 , C12N15/00
CPC分类号: C07K14/47
摘要: The invention provides a human ankyrin family protein (ANFP) and polynucleotides which identify and encode ANFP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of ANFP.
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公开(公告)号:US06348576B1
公开(公告)日:2002-02-19
申请号:US09365705
申请日:1999-08-02
申请人: Jennifer L. Hillman , Neil C. Corley , Purvi Shah
发明人: Jennifer L. Hillman , Neil C. Corley , Purvi Shah
IPC分类号: C07K1447
CPC分类号: C07K14/4702 , A61K38/00
摘要: The invention provides a human cornichon protein (CORN) and polynucleotides which identify and encode CORN. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating and preventing disorders associated with expression of CORN.
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