Process for the preparation of 2-(1-hydroxyalkyl)-5,5-diphenylhydantoin
    92.
    发明授权
    Process for the preparation of 2-(1-hydroxyalkyl)-5,5-diphenylhydantoin 失效
    制备2-(1-羟烷基)-5,5-二苯乙内酰脲的方法

    公开(公告)号:US4709042A

    公开(公告)日:1987-11-24

    申请号:US909140

    申请日:1986-09-19

    IPC分类号: C07D233/72

    CPC分类号: C07D233/72

    摘要: Described is a process for preparing 2-(1-hydroxyalkyl)-5,5-diphenylhydantoin having the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are each independently hydrogen, C.sub.1 -C.sub.20 alkyl, C.sub.3 -C.sub.12 cycloalkyl, C.sub.7 -C.sub.15 aralkyl, unsubstituted or substituted aryl or heteroaryl or alternatively, or R.sub.1 and R.sub.2 together with the carbon atom form a 3 to 12 member cycloalkyl group, the process comprising: reacting diphenylhydantoin with an aldehyde or a ketone in the presence of a strong inorganic base; an alcohol was used as solvent to solubilize the reactants. The reaction is practically complete in 15 minutes.The compounds so prepared are intermediates in the preparation of phenyltoin prodrugs.

    摘要翻译: 描述了一种制备具有式“IMAGE”的2-(1-羟基烷基)-5,5-二苯基乙内酰脲的方法,其中R 1,R 2和R 3各自独立地为氢,C 1 -C 20烷基,C 3 -C 12环烷基,C 7 -C 15芳烷基 ,未取代或取代的芳基或杂芳基,或者或者R 1和R 2与碳原子一起形成3-12元环烷基,该方法包括:在强无机碱存在下使二苯乙内酰脲与醛或酮反应; 使用醇作为溶剂来溶解反应物。 反应在15分钟内完成。 如此制备的化合物是制备苯丁前药的中间体。

    Immunoassay wherein labeled antibody is displaced from immobilized
analyte-analogue
    93.
    发明授权
    Immunoassay wherein labeled antibody is displaced from immobilized analyte-analogue 失效
    其中标记的抗体从固定的分析物类似物置换的免疫测定

    公开(公告)号:US4434236A

    公开(公告)日:1984-02-28

    申请号:US435454

    申请日:1982-10-20

    摘要: A method for the rapid determination of analyte in a sample is provided. The sample is contacted with a solid phase having immobilized thereon an analyte-analogue to which there is displaceably bound a labeled anti-analyte antibody. Because the antibody has greater affinity for the analyte than the analyte-analogue, the labeled antibody is displaced from the solid phase. The complex is separated from the solid phase, and the amount of complex is measured. The measured amount is related to the amount of analyte initially present in the sample.

    摘要翻译: 提供了用于快速测定样品中分析物的方法。 样品与其上固定有分析物类似物的固相接触,可分离地结合标记的抗分析物抗体。 因为抗体对分析物类似物的亲和力较高,所以标记的抗体从固相中移位。 将复合物与固相分离,并测定复合物的量。 测量的量与样品中最初存在的分析物的量有关。

    Cell washing apparatus having radially inwardly directed retaining arms
    94.
    发明授权
    Cell washing apparatus having radially inwardly directed retaining arms 失效
    细胞洗涤装置具有径向向内定向的保持臂

    公开(公告)号:US4431423A

    公开(公告)日:1984-02-14

    申请号:US356714

    申请日:1982-03-10

    IPC分类号: B08B11/00 B04B5/04 B04B9/12

    CPC分类号: B04B5/0421

    摘要: A cell washing apparatus having a pivotally movable sample tube holder provided with a radially inwardly directed arm having a grasping hook thereon. The hook engages a retaining surface disposed radially inwardly of the pivot point of the holder to restrain radial outward movement of the sample tube holder.

    摘要翻译: 一种细胞洗涤装置,其具有可枢转地移动的样品管保持器,其设置有在其上具有抓握钩的径向向内指向的臂。 钩子接合设置在保持器的枢转点的径向内侧的保持表面,以限制样品管保持器的径向向外运动。

    Laminated sheet structures
    97.
    发明授权
    Laminated sheet structures 失效
    层压板结构

    公开(公告)号:US4424253A

    公开(公告)日:1984-01-03

    申请号:US350841

    申请日:1982-02-25

    IPC分类号: B32B25/08 B32B27/08 B32B27/32

    摘要: Blends of chlorinated hydrocarbon rubber selected from chlorosulfonated polyethylene having about 22-28 weight % Cl and 0.4-1.2 weight % S and chlorinated polyethylene having about 22-28 weight % Cl with EPM or EPDM elastomers in a proportion of 75-93% of the former and 7-25% of the latter can be compounded with usual fillers, pigments, stabilizers, and processing aids and formed into sheets which form hot bonded laminate structures with linear ethylene polymer sheets. Such laminate structures have very good adhesion peel strength, good mechanical strength and stretchability and are particularly useful in making pool and pond liners.

    摘要翻译: 选自具有约22-28重量%Cl和0.4-1.2重量%S的氯磺化聚乙烯和约22-28重量%Cl的氯化聚乙烯与EPM或EPDM弹性体的比例为75-93%的氯化烃橡胶的共混物 前者和7-25%的后者可以与通常的填料,颜料,稳定剂和加工助剂混合,并形成为用线性乙烯聚合物片形成热粘合层压结构的片材。 这种层压结构具有非常好的粘附剥离强度,良好的机械强度和拉伸性,并且特别适用于制造池和池塘衬垫。

    Centrifuge rotor apparatus for preparing particle spreads
    98.
    发明授权
    Centrifuge rotor apparatus for preparing particle spreads 失效
    用于制备颗粒传播的离心机转子装置

    公开(公告)号:US4423699A

    公开(公告)日:1984-01-03

    申请号:US15911

    申请日:1979-02-28

    摘要: A centrifuge rotor is described which facilitates the preparation of cell dispersions on microscope slides. The rotor is bowl-like in configuration and defines an annular channel having plural circumferentially disposed septa. The septa provide plural separate regions each adapted to receive removable chambers. The outer wall in each region is flat to accommodate a microscope slide. Each chamber has an outlet orifice adapted to contact the microscope slide. A sample containing blood cells, for example, may be placed in each chamber and the cells centrifugally sedimented against the slide associated with the respective chambers. A gasket at the interface between each slide and its chamber prevents leakage of the sample and a conduit in each chamber permits removal of the supernatant fluid following cell sedimentation.

    摘要翻译: 描述了一种有助于在显微镜载玻片上制备细胞分散体的离心机转子。 转子是碗形的,并且限定了具有多个周向设置的隔片的环形通道。 隔垫提供多个单独的区域,每个区域适于接收可拆卸的室。 每个区域的外壁是平坦的,以容纳显微镜载玻片。 每个室具有适于接触显微镜载玻片的出口孔。 例如,含有血细胞的样品可以放置在每个室中,并且细胞离心沉积在与各个室相关联的载玻片上。 每个滑块和其室之间的接口处的垫圈防止样品泄漏,并且每个室中的导管允许在细胞沉淀后去除上清液。

    Acrylic plastisols and organosols and photosensitive compositions and
elements made therefrom
    99.
    发明授权
    Acrylic plastisols and organosols and photosensitive compositions and elements made therefrom 失效
    丙烯酸增塑溶胶和有机溶胶以及由其制成的感光组合物和元素

    公开(公告)号:US4421619A

    公开(公告)日:1983-12-20

    申请号:US317365

    申请日:1981-11-02

    申请人: Boynton Graham

    发明人: Boynton Graham

    摘要: Thermally coalescible acrylic resin dispersions comprising particles of single-phase, surfactant-free, random acrylic polymers or copolymers, containing at least 80% by weight of acrylic units, dispersed in a surfactant-free medium that comprises a compatible liquid plasticizer that is nonvolatile at room temperature and is not a monomer of any of the polymeric components. Incorporation of a photopolymerizable, ethylenically unsaturated compound provides photosensitive dispersions useful for making relief and planographic printing plates, photoresists, and the like.

    摘要翻译: 含有至少80重量%丙烯酸单元的单相,无表面活性剂,无规丙烯酸聚合物或共聚物颗粒的热可聚结丙烯酸树脂分散体,分散在不含表面活性剂的介质中,该介质包含不挥发性的相容性液体增塑剂 不是任何聚合物组分的单体。 引入可光聚合的烯属不饱和化合物提供用于制备浮雕和平版印刷版,光致抗蚀剂等的光敏分散体。

    Printing process
    100.
    发明授权
    Printing process 失效
    印刷过程

    公开(公告)号:US4421518A

    公开(公告)日:1983-12-20

    申请号:US392785

    申请日:1982-06-28

    申请人: Emery J. Gorondy

    发明人: Emery J. Gorondy

    IPC分类号: D06B11/00 D06P5/28 D06P5/20

    摘要: A process is described for dyeing a disperse dyeable material such as a textile or film comprising the steps of forming an image comprising a dye component which is substantially sublimable at from about 160.degree. to 215.degree. C., on a film of a thermally stable resin which is permeable to said dye component covering the dye image with a paper web or a resinous material and bringing the film into contact with a disperse dyeable material to be dyed while the film and disperse dyeable material are rotated upon a heated drum, with the disperse dyeable material facing the surface of the film opposite the side supporting the image, to thereby transfer said dye component from the film to the textile material.

    摘要翻译: 描述了用于染色分散染色材料如纺织品或薄膜的方法,包括以下步骤:在热稳定树脂的膜上形成包含基本上可升华的染料组分的图像,所述染料组分在约160-215℃下实质升华 所述染料组分可透过所述染料图像用纸幅或树脂材料覆盖,并使所述膜与待染色的分散染色材料接触,同时所述膜和分散染色材料在加热的鼓上旋转, 面向与支撑图像相对的膜的表面的可染色材料,从而将所述染料成分从膜转移到纺织材料。