摘要:
In accordance with the present invention, disclosed herein are compounds of the formula ##STR1## wherein R is straight or branched loweralkyl, R.sub.1 is hydrogen, straight or branched loweralkyl, lowercycloalkyl, amino, loweralkoxy or acylamino, and R.sub.2 is straight or branched loweralkyl, amino, cyclohexyl, morpholino, piperidino, tetrahydrofuranyl, dihydrofuranyl, tetrahydropyranyl, dioxolanyl, 2,2-dimethyl dioxolanyl, dioxanyl, pyrrolidinyl, tetrahydrooxazolyl, and dihydrooxazolyl, and pharmaceutically acceptable salts thereof. The compounds are useful in the treatment of glaucoma.
摘要:
Described is a process for preparing 2-(1-hydroxyalkyl)-5,5-diphenylhydantoin having the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are each independently hydrogen, C.sub.1 -C.sub.20 alkyl, C.sub.3 -C.sub.12 cycloalkyl, C.sub.7 -C.sub.15 aralkyl, unsubstituted or substituted aryl or heteroaryl or alternatively, or R.sub.1 and R.sub.2 together with the carbon atom form a 3 to 12 member cycloalkyl group, the process comprising: reacting diphenylhydantoin with an aldehyde or a ketone in the presence of a strong inorganic base; an alcohol was used as solvent to solubilize the reactants. The reaction is practically complete in 15 minutes.The compounds so prepared are intermediates in the preparation of phenyltoin prodrugs.
摘要:
A method for the rapid determination of analyte in a sample is provided. The sample is contacted with a solid phase having immobilized thereon an analyte-analogue to which there is displaceably bound a labeled anti-analyte antibody. Because the antibody has greater affinity for the analyte than the analyte-analogue, the labeled antibody is displaced from the solid phase. The complex is separated from the solid phase, and the amount of complex is measured. The measured amount is related to the amount of analyte initially present in the sample.
摘要:
A cell washing apparatus having a pivotally movable sample tube holder provided with a radially inwardly directed arm having a grasping hook thereon. The hook engages a retaining surface disposed radially inwardly of the pivot point of the holder to restrain radial outward movement of the sample tube holder.
摘要:
A simplified method for photoimaging a photosensitive layer produces in situ a radiation-opaque photomask on the photosensitive layer or on a cover sheet of the layer. A nonvisible latent image is toned and the toner is transferred to a layer or cover sheet to form an actinic radiation-opaque photomask.
摘要:
An aqueous solution of ethyl or propyl alcohol containing a basic compound such as KOH is shown to etch the surface of polyimide material up to 400 times faster than conventional aqueous KOH etching solutions.
摘要:
Blends of chlorinated hydrocarbon rubber selected from chlorosulfonated polyethylene having about 22-28 weight % Cl and 0.4-1.2 weight % S and chlorinated polyethylene having about 22-28 weight % Cl with EPM or EPDM elastomers in a proportion of 75-93% of the former and 7-25% of the latter can be compounded with usual fillers, pigments, stabilizers, and processing aids and formed into sheets which form hot bonded laminate structures with linear ethylene polymer sheets. Such laminate structures have very good adhesion peel strength, good mechanical strength and stretchability and are particularly useful in making pool and pond liners.
摘要:
A centrifuge rotor is described which facilitates the preparation of cell dispersions on microscope slides. The rotor is bowl-like in configuration and defines an annular channel having plural circumferentially disposed septa. The septa provide plural separate regions each adapted to receive removable chambers. The outer wall in each region is flat to accommodate a microscope slide. Each chamber has an outlet orifice adapted to contact the microscope slide. A sample containing blood cells, for example, may be placed in each chamber and the cells centrifugally sedimented against the slide associated with the respective chambers. A gasket at the interface between each slide and its chamber prevents leakage of the sample and a conduit in each chamber permits removal of the supernatant fluid following cell sedimentation.
摘要:
Thermally coalescible acrylic resin dispersions comprising particles of single-phase, surfactant-free, random acrylic polymers or copolymers, containing at least 80% by weight of acrylic units, dispersed in a surfactant-free medium that comprises a compatible liquid plasticizer that is nonvolatile at room temperature and is not a monomer of any of the polymeric components. Incorporation of a photopolymerizable, ethylenically unsaturated compound provides photosensitive dispersions useful for making relief and planographic printing plates, photoresists, and the like.
摘要:
A process is described for dyeing a disperse dyeable material such as a textile or film comprising the steps of forming an image comprising a dye component which is substantially sublimable at from about 160.degree. to 215.degree. C., on a film of a thermally stable resin which is permeable to said dye component covering the dye image with a paper web or a resinous material and bringing the film into contact with a disperse dyeable material to be dyed while the film and disperse dyeable material are rotated upon a heated drum, with the disperse dyeable material facing the surface of the film opposite the side supporting the image, to thereby transfer said dye component from the film to the textile material.