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110 条记录 (耗时 0.044 秒)

    Method for producing tripeptides and/or peptides longer than tripeptides
    103.
    发明申请
    Method for producing tripeptides and/or peptides longer than tripeptides 审中-公开
    生产长于三肽的三肽和/或肽的方法

    公开(公告)号：US20050032154A1

    公开(公告)日：2005-02-10

    申请号：US10859405

    申请日：2004-06-03

    申请人： Kenzo Yokozeki ,  Sonoko Suzuki ,  Seiichi Hara ,  Isao Abe

    发明人： Kenzo Yokozeki ,  Sonoko Suzuki ,  Seiichi Hara ,  Isao Abe

    IPC分类号： C12N9/16 ,  C12N9/52 ,  C12N9/80 ,  C12P21/02 ,  C12P21/06 ,  C07K5/06

    CPC分类号： C12P21/02 ,  C12N9/16 ,  C12N9/52 ,  C12N9/80

    摘要： It is an object of the present invention to provide a method that allows the production of peptides that are equal to or longer than tripeptides easily, inexpensively and at high yield without going through a complex synthesis method. The inventors of the present invention have found a novel enzyme that efficiently produces a peptide from bacteria belonging to the genus Empedobacter or the genus Sphingobacterium. In the present invention, this enzyme is allowed to act on a carboxy component and an amine component to produce peptides that are equal to or longer than tripeptides.

    摘要翻译： 本发明的目的是提供一种能够容易地，低成本地以高收率生产等于或长于三肽的肽而不经过复合合成方法的方法。 本发明的发明人已经发现了一种新颖的酶，其能有效地从属于Empedobacter属或Sphingobacterium属的细菌产生肽。 在本发明中，使该酶作用于羧基组分和胺组分以产生等于或长于三肽的肽。

    Novel peptide-forming enzyme gene
    104.
    发明申请
    Novel peptide-forming enzyme gene 有权
    新型肽形成酶基因

    公开(公告)号：US20050019864A1

    公开(公告)日：2005-01-27

    申请号：US10855533

    申请日：2004-05-28

    申请人： Seiichi Hara ,  Kenzo Yokozeki ,  Isao Abe ,  Naoto Tonouchi ,  Yasuko Jojima

    发明人： Seiichi Hara ,  Kenzo Yokozeki ,  Isao Abe ,  Naoto Tonouchi ,  Yasuko Jojima

    IPC分类号： C12N1/21 ,  C12N9/00 ,  C12N15/57 ,  C12P21/02 ,  C12Q1/68 ,  C07H21/04 ,  C12N9/64 ,  C12P21/06

    CPC分类号： C12N9/00 ,  C12N9/93 ,  C12P21/00 ,  C12P21/02

    摘要： DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a dipeptide includes producing a dipeptide from a carboxy component and an amine component by using a culture of a microbe belonging to the genus Sphingobacterium and having the ability to form the dipeptide from the carboxy component and the amine component, a microbial cell separated from the culture, treated microbial cell product of the microbe or a peptide-forming enzyme derived from the microbe.

    摘要翻译： 公开了编码肽形成酶的DNA和重组DNA，产生肽形成酶的方法及其制备方法。 制备二肽的方法包括通过使用属于鞘氨醇杆菌属的微生物的培养物从羧基组分和胺组分制备二肽并具有从羧基组分和胺组分形成二肽的能力，微生物细胞 与培养物分离，处理微生物的微生物细胞产物或源自微生物的肽形成酶。

    Method for producing halo-L-tryptophan
    106.
    发明授权
    Method for producing halo-L-tryptophan 失效
    产生卤代-L-色氨酸的方法

    公开(公告)号：US06338957B2

    公开(公告)日：2002-01-15

    申请号：US09800885

    申请日：2001-03-08

    申请人： Norimasa Onishi ,  Kenzo Yokozeki

    发明人： Norimasa Onishi ,  Kenzo Yokozeki

    IPC分类号： C12P1322

    CPC分类号： C12P13/227 ,  C12N1/20 ,  Y10S435/822 ,  Y10S435/873

    摘要： A method for producing halo-L-tryptophan from haloindole, comprising culturing a microorganism in a culture medium and then contacting the microorganism with (a) a mixture comprising haloindole, pyruvic acid and ammonia, or (b) a mixture comprising haloindole, a source of pyruvic acid and ammonia, until the halo-L-tryptophan is produced; and recovering the halo-L-tryptophan.

    摘要翻译： 一种从卤代吲哚生产卤代-L-色氨酸的方法，包括在培养基中培养微生物，然后使微生物与（a）包含卤代吲哚，丙酮酸和氨的混合物接触，或（b）包含卤代吲哚，源 的丙酮酸和氨，直到产生卤代-L-色氨酸; 并回收卤代-L-色氨酸。

    Method for producing D-.alpha.-amino acid
    109.
    发明授权
    Method for producing D-.alpha.-amino acid 失效
    D-α-氨基酸的制备方法

    公开(公告)号：US4211840A

    公开(公告)日：1980-07-08

    申请号：US897003

    申请日：1978-04-17

    申请人： Shigeru Nakamori ,  Kenzo Yokozeki ,  Koji Mitsugi ,  Chikahiko Eguchi ,  Hisao Iwagami

    发明人： Shigeru Nakamori ,  Kenzo Yokozeki ,  Koji Mitsugi ,  Chikahiko Eguchi ,  Hisao Iwagami

    IPC分类号： C07D233/72 ,  C12P13/04 ,  C12P13/24

    CPC分类号： C12P13/04

    摘要： D-.alpha.-amino acids are produced by contacting a 5-substituted hydantoin with an effective amount of an enzyme capable of converting the 5-substituted hydantoin to the D-.alpha.-amino acid produced by a microorganism in an aqueous medium at a pH in the range of 4 to 9, the microorganism being capable of utilizing the D-isomer of the 5-substituted hydantoin as the sole nitrogen source, but substantially incapable of utilizing the L-isomer of the 5-substituted hydantoin as the nitrogen source and the substituent of the 5-position being such that upon reaction with the enzyme, an optically active D-.alpha.-amino acid isomer is produced; and recovering the D-.alpha.-amino acid which accumulates in the aqueous medium.

    摘要翻译： D-α-氨基酸是通过使5-取代的乙内酰脲与有效量的能够将5-取代的乙内酰脲转化为由微生物在水性介质中产生的D-α-氨基酸的酶在pH值 范围为4至9，微生物能够利用5-取代乙内酰脲的D-异构体作为唯一的氮源，但基本上不能利用5-取代的乙内酰脲的L-异构体作为氮源， 5位的取代基使得当与酶反应时，产生光学活性的D-α-氨基酸异构体; 并回收积聚在水性介质中的D-α-氨基酸。