公开(公告)号：US06525815B2

公开(公告)日：2003-02-25

申请号：US10007796

申请日：2001-11-09

Applicant: Helen L. Kung ,  David A. B. Miller

Inventor： Helen L. Kung ,  David A. B. Miller

IPC: G01J328

CPC classification number: G01J3/02 ,  G01J3/0229 ,  G01J3/0256 ,  G01J3/45 ,  G01J3/453

Abstract: A transform spectrometer determines the spectrum of light based on the Talbot effect. Light to be analyzed is passed through a spatially periodic object, thereby generating a series of Talbot images. The intensities of these Talbot images at different optical distances from the spatially periodic object are then detected, and Fourier transformed to determine the spectrum of the light. Preferably, the detector comprises a spatial masking pattern such that the intensities detected are maximized at Talbot planes or at the midpoints between Talbot planes. In one embodiment, the optical distance between the spatially periodic object and the detector is changed in order to detect image intensities at different Talbot planes. In another embodiment, the detector and the spatially periodic object are positioned along a common optical axis at relative angle &thgr; such that different detector rows detect intensities at different Talbot planes. In yet another embodiment, the spatially periodic object is both a grating and a detector, and the Talbot images generated by the grating are reflected off a mirror back to the detector.

Abstract translation: 变换光谱仪基于Talbot效应确定光谱。 要分析的光通过空间周期的物体，从而产生一系列Talbot图像。 然后检测这些Talbot图像在距离空间周期物体的不同光学距离处的强度，并进行傅里叶变换以确定光谱。 优选地，检测器包括空间掩蔽图案，使得检测到的强度在Talbot平面或Talbot平面之间的中点处最大化。 在一个实施例中，改变空间周期性物体与检测器之间的光学距离，以便检测不同Talbot平面处的图像强度。 在另一个实施例中，检测器和空间周期性物体沿着公共光轴以相对角度θ定位，使得不同的检测器行检测不同Talbot平面处的强度。 在另一个实施例中，空间周期性物体既是光栅又是检测器，并且由光栅产生的Talbot图像被反射回到检测器。

公开(公告)号：US06462826B1

公开(公告)日：2002-10-08

申请号：US09462981

申请日：2000-03-06

Applicant: John Howard

Inventor： John Howard

IPC: G01B902

CPC classification number: G01J5/04 ,  G01J1/04 ,  G01J1/0429 ,  G01J3/45 ,  G01J3/453 ,  G01J5/0014 ,  G01J5/0018 ,  G01J5/0044 ,  G01J5/08 ,  G01J5/0803 ,  G01J5/0834 ,  G01J5/58 ,  G01J2005/583 ,  G01J2005/586

Abstract: A method and apparatus for measurement of at least one of brightness, flow velocity and temperature of radiant media are provided. A substantially collimated beam of light having a selected frequency is directed to a linear polariser. The linearly polarised output is directed to an electro-optically active birefringent crystal to separate the output into two characteristic waves and to introduce a first fixed phase delay between the characteristic waves. The birefringent crystal is selectively electro-optically modulated to introduce a second variable phase delay between the characteristic waves and the characteristic waves are combined to interfere prior to detection.

Abstract translation: 提供了用于测量辐射介质的亮度，流速和温度中的至少一个的方法和装置。 具有选定频率的基本上准直的光束被引导到线性偏振器。 线性偏振输出被引导到电光学上有效的双折射晶体，以将输出分离成两个特征波并且在特征波之间引入第一固定相位延迟。 双折射晶体被选择性地电光调制以在特征波之间引入第二可变相位延迟，并且特征波被组合以在检测之前被干扰。

公开(公告)号：US6147762A

公开(公告)日：2000-11-14

申请号：US320705

申请日：1999-05-27

Applicant: Peter Haschberger ,  Nicholas King ,  Erwin Lindermeir

Inventor： Peter Haschberger ,  Nicholas King ,  Erwin Lindermeir

IPC: G01B9/02 ,  G01J3/28 ,  G01J3/42 ,  G01J3/45 ,  G01N21/35

CPC classification number: G01J3/45

Abstract: The correction method of the invention synthesizes a distortion-free interferogram (or spectrum) from a measured interferogram, which has been distorted by detector non-linearities, and a finite series of orthogonal functions derived therefrom. The coefficients of the series of functions are selected with a priori knowledge about the limited spectral sensitivity of the radiation detector, preferably with the method of Gaussian least squares fit of observation, such that the resulting spectrum assumes the value of zero of the distortion-free spectrum outside of the sensitivity range, and in freely-definable ranges. The method of the invention can be used to correct detector non-linearities, as occur in Fourier spectroscopy.

Abstract translation: 本发明的校正方法从已经被检测器非线性扭曲的测量干涉图和从其导出的有限系列正交函数合成了无失真干涉图（或频谱）。 利用关于辐射检测器的有限光谱灵敏度的先验知识来选择一系列函数的系数，优选地采用观测的高斯最小二乘拟合方法，使得所得到的光谱呈现零的无失真值 频谱在灵敏度范围之外，并且具有可自由限定的范围。 本发明的方法可用于校正检测器非线性，如在傅立叶光谱中发生的那样。

公开(公告)号：US5949544A

公开(公告)日：1999-09-07

申请号：US115211

申请日：1998-07-14

Applicant: Christopher J. Manning

Inventor： Christopher J. Manning

IPC: G01B9/02 ,  G01J3/02 ,  G01J3/06 ,  G01J3/28 ,  G01J3/45 ,  G01J9/02

CPC classification number: G01J9/0215 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/06 ,  G01J3/2889 ,  G01J3/45

Abstract: A spectrometer includes an actuator assembly, a mobile mirror assembly responsive to the actuator assembly, a balancing element responsive to the mobile mirror assembly, and a suspension mechanism operatively connected between the mobile mirror assembly, the balancing element and an optical support element in a relative position that isolates substantially all forces arising out of the actuation by the actuator assembly of the mobile mirror assembly and the balancing element.

Abstract translation: 光谱仪包括致动器组件，响应于致动器组件的移动反射镜组件，响应于移动反射镜组件的平衡元件，以及可操作地连接在移动反射镜组件，平衡元件和相对的光学支撑元件之间的悬架机构 位置，其通过移动镜组件和平衡元件的致动器组件基本上分离由致动产生的所有力。

公开(公告)号：US5945675A

公开(公告)日：1999-08-31

申请号：US819144

申请日：1997-03-17

Applicant: Donald C. Malins

Inventor： Donald C. Malins

IPC: C12N15/09 ,  C12Q1/68 ,  G01J3/45 ,  G01N21/35 ,  G01N33/15 ,  G01N33/566 ,  A61B6/00

CPC classification number: G01N21/35 ,  G01J3/45 ,  C12Q1/6886 ,  C12Q2600/112 ,  G01N2021/3595 ,  G01N2201/129 ,  G06F19/24

Abstract: Methods of screening for a tumor or tumor progression to the metastatic state are a provided. The screening methods are based on the characterization of DNA by principal components analysis of spectral data yielded by Fourier transform-infrared spectroscopy of DNA samples. The methods are applicable to a wide variety of DNA samples and cancer types.

Abstract translation: 提供筛选肿瘤或肿瘤进展至转移状态的方法。 筛选方法基于通过DNA样品的傅立叶变换红外光谱产生的光谱数据的主成分分析对DNA的表征。 该方法适用于各种DNA样品和癌症类型。

公开(公告)号：US5513828A

公开(公告)日：1996-05-07

申请号：US285116

申请日：1994-08-03

Applicant: Peter R. Solomon

Inventor： Peter R. Solomon

IPC: G01B9/02

CPC classification number: G01J3/45 ,  G01J3/0202

Abstract: The structure serves to support any of various elements and objects, normally for translational movement. It is effectively divided, by pivot points on an intermedial axis, into two opposite portions of equal mass, thus affording to the structure immunization against translational forces transmitted through those points. The opposite portions also have their centers of gravity remotely located, so as to generate a counteracting torque in response to moments of rotational inertia transmitted through the pivot points. Integrally formed planar pieces are assembled to provide contiguous elongate elements and an interposed connecting web element, a plurality of which web elements produce a flexure joint in the structure.

Abstract translation: 该结构用于支撑通常用于平移运动的各种元件和物体中的任何一种。 它通过中间轴上的枢轴点被有效地分成两个相等质量的相对部分，从而为通过这些点传递的平移力提供结构免疫。 相对部分还具有远离其重心的位置，以响应于通过枢转点传递的旋转惯性力矩而产生抵消力矩。 整体形成的平面件被组装以提供连续的细长元件和插入的连接腹板元件，多个网状元件在结构中产生挠曲接头。

公开(公告)号：US5003184A

公开(公告)日：1991-03-26

申请号：US398692

申请日：1989-08-25

Applicant: Robert N. Hunt ,  Robert L. Sandridge

Inventor： Robert N. Hunt ,  Robert L. Sandridge

IPC: G01J3/10 ,  G01J3/45 ,  G01N21/35

CPC classification number: G01J3/108 ,  G01J3/45 ,  G01N21/3504

Abstract: An infrared source suitable for use as a remote source for infrared interferometer spectrometers. This device is composed of a heat source, a black body radiating element and a concave reflector. A support to maintain the heat source and black body radiating elements in proper position is also preferably included. The device of the present invention enhances the accuracy and sensitivity of gas sensing devices based upon measurement of background infrared radiation, and allows the remote infrared source to be used in locations in which ignitable materials may be present.

公开(公告)号：US4927269A

公开(公告)日：1990-05-22

申请号：US304697

申请日：1989-01-31

Applicant: Axel Keens ,  Arno Simon

Inventor： Axel Keens ,  Arno Simon

IPC: G01J3/45

CPC classification number: G01J3/45

Abstract: An interferogram is formed as in the prior art by dividing a beam of radiation from the source into two beams and interfering these beams so as to form an interferogram on the detector. A Fourier transform is then made of this interferogram. This transform has a signal spectrum above the cutoff frequency of the detector; and because of non-linearities in the detector and in the electronic signal processing circuitry, this transform also has a spectrum below the cutoff frequency of the detector. In accordance with the invention, two correction factors are calculated from this Fourier transform and these correction factors are then used to calculate a corrected interferogram. The first correction factor is evaluated by determining from the portion of the spectrum below the cutoff frequency a valve for the spectral signal at zero frequency. In addition, the integral of the square of the spectrum signal above the cutoff frequency is determined and the correction factor is found by dividing the signal at zero frequency by the integral of the square of the spectrum above the cutoff. The second correction factor is a function of the first correction factor and the integral of the spectrum signal above cutoff. These two corrections factors are then used in calculating a second order approximation to a corrected interferogram. Finally to produce the corrected Fourier transform, a Fourier transformation is made.

Abstract translation: 通过将来自源的辐射束分成两束并干涉这些光束以形成在现有技术中形成干涉图，以便在检测器上形成干涉图。 然后由该干涉图进行傅里叶变换。 该变换的信号频谱高于检测器的截止频率; 并且由于检测器和电子信号处理电路中的非线性，该变换也具有低于检测器的截止频率的频谱。 根据本发明，从该傅里叶变换计算出两个校正因子，然后使用这些校正因子来计算校正的干涉图。 通过从零频率处的频谱信号的频谱的截止频率以下的频谱的部分确定来评估第一校正因子。 此外，确定高于截止频率的频谱信号的平方的积分，并且通过将零频率处的信号除以高于截止频率的频谱的平方的积分来确定校正因子。 第二校正因子是第一校正因子和高于截止频谱信号的积分的函数。 然后将这两个校正因子用于计算校正干涉图的二阶近似。 最后，为了产生经校正的傅里叶变换，进行傅里叶变换。

公开(公告)号：US4755056A

公开(公告)日：1988-07-05

申请号：US63921

申请日：1987-06-19

Applicant: Makoto Yasuda ,  Tsune Miyashita

Inventor： Makoto Yasuda ,  Tsune Miyashita

IPC: G01J3/10 ,  G01J3/45 ,  G01N21/01 ,  G01N21/33 ,  H01J61/20 ,  G01J3/42

CPC classification number: G01J3/10 ,  H01J61/20 ,  G01J3/45 ,  G01N21/33

Abstract: An instrument for spectroscopy according to this invention uses a metal halide lamp, in which at least mercury and dysprosium halide are enclosed, as the light source for the purpose of effecting measurements for a wavelength region extending from the ultraviolet to the visible light with a single light source. This metal halide lamp has a spectre, which is effective in a wavelength region extending from about 200 nm to about 700 nm.

Abstract translation: 根据本发明的光谱仪器使用其中封入了至少汞和镝卤化物的金属卤化物灯作为光源，用于对从紫外线到可见光延伸的波长区域进行单次测量 光源。 该金属卤化物灯具有幽灵，其在从约200nm至约700nm延伸的波长区域中有效。

公开(公告)号：US20240324875A1

公开(公告)日：2024-10-03

申请号：US18737811

申请日：2024-06-07

Applicant: Digital Diagnostics Inc.

Inventor： Michael D. Abramoff ,  Edward DeHoog

IPC: A61B3/10 ,  A61B3/00 ,  A61B3/12 ,  A61B3/14 ,  G01B9/02 ,  G01B9/02015 ,  G01B9/02091 ,  G01J3/45

CPC classification number: A61B3/102 ,  A61B3/0008 ,  A61B3/0025 ,  A61B3/1005 ,  A61B3/1225 ,  A61B3/14 ,  G01B9/02027 ,  G01B9/02028 ,  G01B9/02044 ,  G01B9/02091 ,  G01J3/45 ,  G01B2290/65

Abstract: Provided is a snapshot spectral domain optical coherence tomographer comprising a light source providing a plurality of beamlets; a beam splitter, splitting the plurality of beamlets into a reference arm and a sample arm; a first optical system that projects the sample arm onto multiple locations of a sample; a second optical system for collection of a plurality of reflected sample beamlets; a third optical system projecting the reference arm to a reflecting surface and receiving a plurality of reflected reference beamlets; a parallel interferometer that provides a plurality of interferograms from each of the plurality of sample beamlets with each of the plurality of reference beamlets; an optical image mapper configured to spatially separate the plurality of interferograms; a spectrometer configured to disperse each of the interferograms into its respective spectral components and project each interferogram in parallel; and a photodetector providing photon quantification.