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公开(公告)号：US20210392923A1
公开(公告)日：2021-12-23
申请号：US17411029
申请日：2021-08-24
Applicant: DSM IP ASSETS B.V. , EVONIK OPERATIONS GMBH
Inventor： Dirk Luc DE VRIENDT
Abstract: The present invention relates to a blend formulation (I) comprising (i) at least 50 weight-% (wt-%), based on the total weight of the blend formulation, of a LC-PUFA-containing composition (ii) 10-50 wt-%, based on the total weight of silcate.
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公开(公告)号：US20210386645A1
公开(公告)日：2021-12-16
申请号：US17283111
申请日：2019-10-04
Applicant: DSM IP ASSETS B.V.
Inventor： Christine MENDROK-EDINGER
Abstract: The present invention is concerned with the use of a PEG-emulsifier, optionally in combination with hyaluronic acid or a salt thereof for suppressing discoloration in topical compositions comprising vitamin B6 or a derivative thereof. Furthermore, the invention relates to a method for reducing discoloration of topical compositions containing vitamin B6 or a derivative thereof, comprising preparing a topical composition comprising vitamin B6, a PEG-emulsifiers and optionally hyaluronic acid and a cosmetically acceptable carrier.
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公开(公告)号：US11191869B2
公开(公告)日：2021-12-07
申请号：US16524435
申请日：2019-07-29
Applicant: DSM IP Assets B.V.
Inventor： Timothy A. Ringeisen , William Christopher Wattengel
IPC: A61B17/68 , A61F2/28 , A61B17/70 , C08L89/06 , A61L27/16 , A61B17/72 , A61L26/00 , A61L27/46 , A61L27/48 , A61L27/52 , A61L27/58 , C08H1/06 , C08L5/04 , C08L5/08 , C08L67/04 , A61L27/24 , A61L27/56 , A61L27/18 , A61L27/20 , A61L27/22 , A61L27/36 , A61L27/38 , A61F2/00 , A61F2/24 , A61F2/30 , A61F2/44 , A61L27/12 , A61L27/26 , A61L27/54 , C08K3/013 , A61B17/00 , A61F2/42
Abstract: This invention includes malleable, biodegradable, fibrous compositions for application to a tissue site in order to promote or facilitate new tissue growth. One aspect of this invention is a fibrous component that provides unique mechanical and physical properties. The invention may be created by providing a vessel containing a slurry, said slurry comprising a plurality of natural or synthetic polymer fibers and at least one suspension fluid, wherein the polymer fibers are substantially evenly dispersed and randomly oriented throughout the volume of the suspension fluid; applying a force, e.g., centrifugal, to said vessel containing said slurry, whereupon said force serves to cause said polymer fibers to migrate through the suspension fluid and amass at a furthest extent of the vessel, forming a polymer material, with said polymer material comprising polymer fibers of sufficient length and sufficiently viscous, interlaced, or interlocked to retard dissociation of said polymer fibers.
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公开(公告)号：US11168054B2
公开(公告)日：2021-11-09
申请号：US16061418
申请日：2016-12-14
Applicant: DSM IP ASSETS B.V.
Inventor： Igor Bendik , Piero Geotti-Bianchini , Marc Heidl , Eileen Jackson , Alexander Schlifke-Poschalko
IPC: C07C401/00 , A61K8/34 , A61Q19/08
Abstract: Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
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公开(公告)号：US11160743B2
公开(公告)日：2021-11-02
申请号：US16339501
申请日：2017-10-09
Applicant: DSM IP ASSETS B.V.
Inventor： Bernd Schlegel
Abstract: The invention relates to an improved process for the manufacture of nano-sized organic UV absorbers having a mean particle size distribution (Dv50) determined by light scattering of less than 200 nm.
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Patent Agency Ranking
公开(公告)号：US20210317420A1
公开(公告)日：2021-10-14
申请号：US17345610
申请日：2021-06-11
Applicant: DSM IP ASSETS B.V.
Inventor： Paulus Petrus DE WAAL , Ingrid Maria VUGT - VAN LUTZ , Jozef Petrus Johannes SCHMITZ , Hans Marinus Charles Johannes DE BRUIJN
Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter, wherein the recombinant yeast comprises overexpression of one or more PPP-genes. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.
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公开(公告)号：US20210309567A1
公开(公告)日：2021-10-07
申请号：US17218582
申请日：2021-03-31
Applicant: DSM IP Assets B.V.
Inventor： Meng HE , Thomas FAUVELL , Eric URRUTI
IPC: C03C25/285 , G02B6/02 , C09D7/48 , C03C25/6226
Abstract: Disclosed herein are compositions for coating an optical fiber containing an optional reactive monomer and/or oligomer, a self-healing component with self-healing moieties, an initiator component, and optionally an additive component. The self-healing component preferably includes polymerizable moieties. Such compositions contain greater than 30% by weight of the self-healing component, and/or greater than 0.015 equivalents of self-healing moieties per 100 g of the composition. Also disclosed herein are coated optical fibers having a glass fiber, at least one coating layer and an optional ink layer, which are configured to possess self-healing properties and/or stress relaxation behavior. Further disclosed are methods for coating self-healing optical fibers, and optical fiber cables comprising a one or more self-healing coated optical fibers.
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公开(公告)号：US11136600B2
公开(公告)日：2021-10-05
申请号：US15766184
申请日：2016-10-03
Applicant: DSM IP Assets B.V.
Inventor： Ioannis Papapetridis , Jacobus Thomas Pronk , Antonius Jeroen Adriaan Van Maris , Paul Klaassen
IPC: C12P7/02 , C12P7/10 , C12N1/18 , C12N9/00 , C12N9/04 , C12N9/02 , C12N9/12 , C12N9/18 , C12N15/52
Abstract: The present invention relates to a eukaryotic cell that is genetically modified comprising one or more heterologous gene encoding: a) D-glucose-6-phosphate dehydrogenase and/or b) 6-phosphogluconate dehydrogenase; and/or c) glucose dehydrogenase, gluconolactonase and gluconate kinase, wherein a), b) and glucose dehydrogenase in c) are NAD+ dependent.
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公开(公告)号：US11078504B2
公开(公告)日：2021-08-03
申请号：US16063810
申请日：2016-12-22
Applicant: DSM IP ASSETS B.V.
Inventor： Alrik Pieter Los , Zheng Zhao , René Verwaal , Jacobus Thomas Pronk , Rolf Poldermans
Abstract: The present invention relates to a host cell which is capable of producing a dicarboxylic acid and which comprises at least one genetic modification in its genome resulting in the deficiency of at least one enzymatic step catalysing the oxidation of a cofactor. The invention also relates to a process for producing a dicarboxylic acid, which method comprises fermenting such a host cell in a suitable fermentation medium and producing the dicarboxylic acid.
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公开(公告)号：US20210230614A1
公开(公告)日：2021-07-29
申请号：US17176073
申请日：2021-02-15
Applicant: DSM IP Assets B.V.
Inventor： Jacobus Thomas PRONK , Antonius Jeroen Adriaan VAN MARIS , Victor Gabriel GUADALUPE MEDINA
Abstract: The present invention relates to a yeast cell, in particular a recombinant yeast cell, the cell lacking enzymatic activity needed for the NADH-dependent glycerol synthesis or the cell having a reduced enzymatic activity with respect to the NADH-dependent glycerol synthesis compared to its corresponding wild-type yeast cell, the cell comprising one or more heterologous nucleic acid sequences encoding an NAD+-dependent acetylating acetaldehyde dehydrogenase (EC 1.2.1.10) activity. The invention further relates to the use of a cell according to the invention in the preparation of ethanol.
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