公开(公告)号：US07713900B2

公开(公告)日：2010-05-11

申请号：US12133551

申请日：2008-06-05

Applicant: Albert S Chan ,  Gang Chen ,  Rongwei Guo ,  Jing Wu

Inventor： Albert S Chan ,  Gang Chen ,  Rongwei Guo ,  Jing Wu

IPC: C07F9/32 ,  C07F15/04 ,  C07F15/00 ,  B01J31/12

CPC classification number: B01J31/2409 ,  B01J2231/44 ,  B01J2531/16 ,  B01J2531/821 ,  B01J2531/822 ,  B01J2531/824 ,  B01J2531/827 ,  B01J2531/828 ,  B01J2531/847 ,  C07F9/6512 ,  C07F15/0066

Abstract: The present invention provides bipyrimidinyl diphosphine compounds of the formula wherein R is optionally substituted alkyl, cycloalkyl, aryl or heteroaryl; R′ and R″ are independently optionally substituted alkyl, cycloalkyl, aryl or heteroaryl; or an enantiomer thereof; or an enantiomeric mixture thereof. The compounds of the formula (I) are chiral atropisomeric bipyrimidinyl diphosphine compounds and, thus, may be employed as ligands to generate chiral transition metal catalysts which may be applied in a variety of asymmetric reactions, e.g., in palladium catalyzed asymmetric allylic substitution reactions. The compounds of the present invention are easily accessible in high enantiomeric purity according to the methods disclosed herein.

公开(公告)号：US07678715B2

公开(公告)日：2010-03-16

申请号：US11962674

申请日：2007-12-21

Applicant: Hemant P. Mungekar ,  Jing Wu ,  Young S. Lee ,  Anchuan Wang

Inventor： Hemant P. Mungekar ,  Jing Wu ,  Young S. Lee ,  Anchuan Wang

IPC: H01L21/00 ,  C23C14/08

CPC classification number: H01L21/3185 ,  C23C16/345 ,  C23C16/505 ,  H01L21/0217 ,  H01L21/02211 ,  H01L21/02274 ,  H01L21/31111

Abstract: The present invention pertains to methods of depositing low wet etch rate silicon nitride films on substrates using high-density plasma chemical vapor deposition techniques at substrate temperatures below 600° C. The method additionally involves the maintenance of a relatively high ratio of nitrogen to silicon in the plasma and a low process pressure.

Abstract translation: 本发明涉及在低于600℃的衬底温度下使用高密度等离子体化学气相沉积技术在衬底上沉积低湿蚀刻速率的氮化硅膜的方法。该方法还涉及维持相对较高的氮与硅比例 等离子体和低过程压力。

公开(公告)号：US07629271B1

公开(公告)日：2009-12-08

申请号：US12233881

申请日：2008-09-19

Applicant: Jing Wu ,  Anchuan Wang ,  Robert T. Chen ,  Young S. Lee

Inventor： Jing Wu ,  Anchuan Wang ,  Robert T. Chen ,  Young S. Lee

IPC: H01L21/31

CPC classification number: H01L21/3146 ,  C23C16/0218 ,  C23C16/26

Abstract: A method for forming a compressive film over a field effect transistor over a substrate is provided. The field effect transistor includes a channel region between a drain and a source within the substrate. The channel region is controlled by a gate electrode. The method includes depositing a diamond-like carbon (DLC) film over the field effect transistor to compress the channel region by generating a plasma of a processing gas including a precursor gas and an additive gas, wherein the precursor substantially includes only C2H2 and the additive gas includes Ar.

Abstract translation: 提供了一种在衬底上形成场效应晶体管上的压缩膜的方法。 场效应晶体管包括在衬底内的漏极和源极之间的沟道区域。 沟道区域由栅电极控制。 该方法包括在场效应晶体管上沉积类金刚石碳（DLC）膜，以通过产生包括前体气体和添加气体的处理气体的等离子体来压缩沟道区域，其中前体基本上仅包含C2H2和添加剂 气体包括Ar。

公开(公告)号：US07574652B2

公开(公告)日：2009-08-11

申请号：US10465222

申请日：2003-06-20

Applicant: Alison Joan Lennon ,  Timothy Charles Edgoose ,  Sue-Ken Yap ,  Sammy Chan ,  Jing Wu ,  Lena Qian ,  Khanh Phi Van Doan ,  Joshua Brendon Worrill

Inventor： Alison Joan Lennon ,  Timothy Charles Edgoose ,  Sue-Ken Yap ,  Sammy Chan ,  Jing Wu ,  Lena Qian ,  Khanh Phi Van Doan ,  Joshua Brendon Worrill

IPC: G06F17/00

CPC classification number: G06F17/30554 ,  G06F17/30389 ,  G06F17/30569

Abstract: Access to heterogeneous data sources may be obtained by interactively determining transformations for use in mapping at least one source data component from at least one data source to a target data component. Selection of at least one the source data component is detected. A corresponding list of representative data examples is generated for each selected source data component. A resulting list of representative data examples is compiled for the target data component from the lists of representative data examples of the selected source data components, the resulting list of data examples being representative of the target data component. A modification of an example is identified from the resulting list of examples representative of the target data component, the example being modified as a single textual entity. At least one transformation is determined, by inferring from the modified example, to be applied to at least one source data component.

Abstract translation: 可以通过交互地确定用于将至少一个源数据组件从至少一个数据源映射到目标数据组件的变换来获得对异构数据源的访问。 检测到至少一个源数据分量的选择。 对于每个所选择的源数据组件生成相应的代表数据示例列表。 从所选择的源数据组件的代表性数据示例的列表中，针对目标数据组件编制代表性数据示例的结果列表，所得到的数据示例列表表示目标数据组件。 从表示目标数据组件的示例的所得列表中识别示例的修改，该示例被修改为单个文本实体。 通过从修改的示例推断确定要应用于至少一个源数据组件的至少一个变换。

公开(公告)号：US20080090817A1

公开(公告)日：2008-04-17

申请号：US11951097

申请日：2007-12-05

Applicant: Simeon Bowers ,  Albert Garofalo ,  Roy Hom ,  Andrei Konradi ,  Matthew Mattson ,  Martin Neitzel ,  Christopher Semko ,  Anh Truong ,  Jing Wu ,  Ying-zi Xu

Inventor： Simeon Bowers ,  Albert Garofalo ,  Roy Hom ,  Andrei Konradi ,  Matthew Mattson ,  Martin Neitzel ,  Christopher Semko ,  Anh Truong ,  Jing Wu ,  Ying-zi Xu

IPC: A61K31/5365 ,  A61K31/437 ,  A61P25/28 ,  C07D497/04 ,  C07D497/14 ,  C07D471/14 ,  A61K31/4985

CPC classification number: C07D451/14 ,  C07D471/08 ,  C07D471/18 ,  C07D471/22 ,  C07D498/08

Abstract: The invention provides N-cyclic sulfonamido compounds and salts of Formula I: wherein A is as described in the specification and R1 and R2 combine to form a [3.3.1] or a [3.2.1] ring system, where the nitrogen is attached to the two bridgehead carbons, and the [3.3.1] or [3.2.1] ring systems are optionally fused with an heteroaryl or heterocycloalkyl ring. Compounds of Formula I are useful in treating or preventing cognitive disorders, such as Alzheimer's Disease. The invention also encompasses pharmaceutical compositions comprising compounds of Formula I, methods of treating cognitive disorders, such as Alzheimer's disease, and the intermediates useful in preparing the compounds of Formula I.

Abstract translation: 本发明提供N-环磺酰氨基化合物和式I的盐：其中A如说明书中所述，R 1和R 2 2结合形成[3.3.1 ]或[3.2.1]环体系，其中氮连接到两个桥头堡碳上，并且[3.3.1]或[3.2.1]环体系任选地与杂芳基或杂环烷基环稠合。 式I的化合物可用于治疗或预防认知障碍，例如阿尔茨海默病。 本发明还包括含有式I化合物的药物组合物，治疗认知障碍的方法，例如阿尔茨海默氏病，以及可用于制备式I化合物的中间体。

公开(公告)号：US07345056B2

公开(公告)日：2008-03-18

申请号：US11465726

申请日：2006-08-18

Applicant: Simeon Bowers ,  Albert W. Garofalo ,  Roy K. Hom ,  Andrei W. Konradi ,  Matthew N. Mattson ,  Martin L. Neitzel ,  Christopher M. Semko ,  Anh P. Truong ,  Jing Wu ,  Ying-zi Xu

Inventor： Simeon Bowers ,  Albert W. Garofalo ,  Roy K. Hom ,  Andrei W. Konradi ,  Matthew N. Mattson ,  Martin L. Neitzel ,  Christopher M. Semko ,  Anh P. Truong ,  Jing Wu ,  Ying-zi Xu

IPC: A01N43/42 ,  A61K31/44 ,  C07D487/00 ,  C07D491/00 ,  C07D451/02

CPC classification number: C07D451/14 ,  C07D471/08 ,  C07D471/18 ,  C07D471/22 ,  C07D498/08

Abstract: The invention provides N-cyclic sulfonamido compounds and salts of Formula I: wherein A is as described in the specification and R1 and R2 combine to form a [3.3.1] or a [3.2.1] ring system, where the nitrogen is attached to the two bridgehead carbons, and the [3.3.1] or [3.2.1] ring systems are optionally fused with an heteroaryl or heterocycloalkyl ring. Compounds of Formula I are useful in treating or preventing cognitive disorders, such as Alzheimer's Disease. The invention also encompasses pharmaceutical compositions comprising compounds of Formula I, methods of treating cognitive disorders, such as Alzheimer's disease, and the intermediates useful in preparing the compounds of Formula I.

Abstract translation: 本发明提供N-环磺酰氨基化合物和式I的盐：其中A如说明书中所述，R 1和R 2 2结合形成[3.3.1 ]或[3.2.1]环体系，其中氮连接到两个桥头堡碳上，并且[3.3.1]或[3.2.1]环体系任选地与杂芳基或杂环烷基环稠合。 式I的化合物可用于治疗或预防认知障碍，例如阿尔茨海默病。 本发明还包括含有式I化合物的药物组合物，治疗认知障碍的方法，例如阿尔茨海默氏病，以及可用于制备式I化合物的中间体。

公开(公告)号：US20070123531A1

公开(公告)日：2007-05-31

申请号：US10555508

申请日：2004-04-30

Applicant: Albert Garofalo ,  Jay Tung ,  Michael Pleiss ,  Jing Wu ,  David Wone ,  Ashley Guinn ,  Darren Dressen ,  Jennifer Marugg ,  Martin Neitzel

Inventor： Albert Garofalo ,  Jay Tung ,  Michael Pleiss ,  Jing Wu ,  David Wone ,  Ashley Guinn ,  Darren Dressen ,  Jennifer Marugg ,  Martin Neitzel

IPC: A61K31/5377 ,  A61K31/4709 ,  A61K31/4439 ,  A61K31/416 ,  A61K31/4178 ,  A61K31/427 ,  A61K31/423 ,  C07D413/02 ,  C07D417/02 ,  C07D405/02 ,  C07D403/02

CPC classification number: C07D401/12 ,  C07D231/16 ,  C07D231/40 ,  C07D403/12 ,  C07D417/12

Abstract: Disclosed are compounds that are bradykinin B1 receptor antagonists and are useful for treating diseases, or relieving adverse symptoms associated with disease conditions, in mammals mediated by bradykinin B1 receptor. Certain of the compounds exhibit increased potency and are also expected to exhibit increased duration of action.

Abstract translation: 公开了缓激肽B1受体拮抗剂的化合物，可用于治疗由缓激肽B1受体介导的哺乳动物中疾病或与疾病状况相关的不良症状。 某些化合物表现出增加的效力，并且还预期表现出增加的作用持续时间。

公开(公告)号：US20070053359A1

公开(公告)日：2007-03-08

申请号：US11467953

申请日：2006-08-29

Applicant: Jing Wu ,  Michel Savoie

Inventor： Jing Wu ,  Michel Savoie

IPC: H04L12/56

CPC classification number: H04J3/14 ,  H04L45/02 ,  H04L45/28 ,  H04L45/507 ,  H04L45/64

Abstract: The invention provides a distributed back-up mechanism and a two-step method for facilitating fast control plane recovery in a switched network network. In a preferred embodiment, a Label Information Database (LID) maintained at a control node of a GMPLS network is mirrored to an upstream node using the Label Distribution Protocol (LDP). After a control plane interruption resulting in the LDP restart, the control node, using the mirrored information at the upstream node, conducts first a fast coarse LID recovery wherein only the idle labels are identified, to enable the restarted LDP session to process new connection setup. A detailed LDP state information recovery performs in the background in parallel to the normal LDP operations, e.g. using on-demand LDP queries.

Abstract translation: 本发明提供了分布式备份机制和用于促进交换网络中的快速控制平面恢复的两步法。 在优选实施例中，使用标签分发协议（LDP）将维护在GMPLS网络的控制节点处的标签信息数据库（LID）镜像到上游节点。 在导致LDP重新启动的控制平面中断之后，使用上游节点处的镜像信息的控制节点首先进行快速粗略LID恢复，其中仅标识空闲标签，以使得重启的LDP会话能够处理新的连接设置 。 详细的LDP状态信息恢复在背景中与正常的LDP操作并行执行，例如， 使用按需LDP查询。

公开(公告)号：US07153847B2

公开(公告)日：2006-12-26

申请号：US10733877

申请日：2003-12-12

Applicant: Jing Wu ,  Jay S. Tung ,  Jeffrey S. Nissen ,  R. Jeffrey Neitz ,  James A. Audia ,  Thomas E. Mabry

Inventor： Jing Wu ,  Jay S. Tung ,  Jeffrey S. Nissen ,  R. Jeffrey Neitz ,  James A. Audia ,  Thomas E. Mabry

IPC: C07D487/00 ,  C07D491/00 ,  A61K31/55

CPC classification number: C07D471/04 ,  A61K31/40 ,  A61K31/4015 ,  A61K31/445 ,  A61K31/5513 ,  A61K38/05 ,  C07C237/22 ,  C07C2603/32 ,  C07D223/18 ,  C07D307/33 ,  C07D311/76 ,  C07D471/06 ,  C07D471/08

Abstract: Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

公开(公告)号：US07130926B1

公开(公告)日：2006-10-31

申请号：US09891011

申请日：2001-06-25

Applicant: Jing Wu ,  Delfin Y. Montuno ,  Guoqiang Wang

Inventor： Jing Wu ,  Delfin Y. Montuno ,  Guoqiang Wang

IPC: G06F15/16

CPC classification number: H04L45/50 ,  H04L45/00 ,  H04L45/28 ,  H04L45/54

Abstract: Label information used by a downstream LSR is mirrored on an upstream LSR. In particular, a copy of the label information database in the downstream LSR from LDP sessions is stored on the upstream LSR. The label information database and corresponding mirror are synchronized. The mirror is employed to facilitate recovery from control plane failure through comparison of the label information database with the mirror. For example, the intersection of the label information database and the mirror may be calculated and employed as the updated label information database and mirror.

Abstract translation: 下游LSR使用的标签信息在上游LSR上镜像。 具体来说，LDP会话的下游LSR中的标签信息数据库的副本存储在上游LSR中。 标签信息数据库和相应的镜像同步。 通过将标签信息数据库与镜像进行比较，可以使用镜子来方便从控制平面故障恢复。 例如，可以计算标签信息数据库和镜像的交集，并将其用作更新的标签信息数据库和镜像。