-
公开(公告)号：US20240425878A1
公开(公告)日：2024-12-26
申请号：US18437160
申请日：2024-02-08
Applicant: The Regents of the University of California
Inventor： Jan Nolta , Karen Pepper , Fernando Fierro , Gerhard Bauer
Abstract: This disclosure relates to vectors, isolated cells, compositions, and methods for the treatment of critical limb ischemia and associated disorders. One aspect of the disclosure relates to a vector comprising a nucleic acid encoding a 165A isoform VEGF protein and a promoter that regulates expression of the nucleic acid encoding the VEGF.
-
公开(公告)号：US12178130B2
公开(公告)日：2024-12-24
申请号：US17295851
申请日：2019-11-20
Applicant: The Regents of the University of California
Inventor： Renkun Chen , Sahngki Hong
Abstract: Thermoelectric devices (TE) devices may be used to power wearable electronics, such as watches and sensors by harvesting heat from the body. These TE devices may fully power or partially power the wearable devices to extend a usage time, or to recharge a battery. In other example embodiments, TE devices can be used to provide heating and/or cooling. The TE devices can be integrated into garments such as clothes, vests, and armbands for outdoor and indoor environments. For outdoor environments, applications include, but are not limited to, sports such as golfing, bicycling, running, walking, training, soccer, hiking, and other outdoor activities related to occupations, such as construction, fire-fighting, military operations, law enforcement, farming, underground mining, and so on. In other example embodiments, TE devices can be used to provide thermal camouflaging for people and objects so as to not be seen by thermal imaging devices.
-
123.发明授权公开(公告)号：US12176470B2
公开(公告)日：2024-12-24
申请号：US16994391
申请日：2020-08-14
Applicant: The Regents of the University of California
Inventor： Lorenzo Ferrari , Zhaowei Liu
Abstract: A light emitting diode may include a light emission layer and a charge transport layer disposed on the light emission layer. A grating including a plurality of nanoholes may be formed by removing a portion of the charge transport layer and/or the light emission layer and depositing a plasmonic metamaterial on a remaining portion of the charge transport layer and/or the light emission layer. The nanoholes may include the plasmonic metamaterial deposited inside the recesses formed by the remaining portion of the charge transport layer and/or the light emission layer, with an additional portion of the charge transport layer disposed on top. A pitch, diameter, and/or depth of the nanoholes may be configured to maximize the quantum efficiency of the light emitting diode, especially at a microscale of less than 100 microns.
-
公开(公告)号：US20240418582A1
公开(公告)日：2024-12-19
申请号：US18337272
申请日：2023-06-19
Applicant: The Regents of the University of California
Inventor： Tania Morimoto , Cédric Girerd , Daegue Park , Dinesh Bharadia , Agrim Gupta , Shayaun Bashar
IPC: G01L1/14
Abstract: A preferred embodiment provides a deformable passive force sensor that induces a change in an interrogation RF signal present on a conductive connection to produce a changed reflective signal and an ID circuit that responds with an ID and the changed reflective signal.
-
公开(公告)号：US20240416008A1
公开(公告)日：2024-12-19
申请号：US18443314
申请日：2024-02-16
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Dino Di Carlo , Westbrook Weaver , Tatiana Segura , Jaekyung Koh , Philip Scumpia , Donald R. Griffin
Abstract: A hydrogel material for use in a human subject or other mammal includes a collection of microgel particles having one or more network cross linker components, wherein the microgel particles, when exposed to an endogenous or exogenous annealing agent, links the microgel particles together in situ to form a covalently-stabilized scaffold of microgel particles having pores formed between the microgel particles wherein the pores are substantially devoid of hydrogel.
-
Patent Agency Ranking
公开(公告)号：US20240415858A1
公开(公告)日：2024-12-19
申请号：US18694720
申请日：2022-09-23
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Michael Demetriou , Michael Sy , Alexander Brandt
IPC: A61K31/7008 , A61K9/00 , A61P25/00
Abstract: The present invention features compositions and methods for the repair of myelin and/or treatment of demyelinating diseases. The demyelinating disease may be multiple sclerosis (MS), optic neuritis, myelin oligodendrocyte glycoprotein antibody associated disease, neuromyelitis optica spectrum disorder, transverse myelitis, or acute disseminated encephalomyelitis. The compositions may include N-acetylglucosamine (GIcNAc), GlcNAc-6-acetate, or a combination thereof. The method may involve administering the compositions to a subject in need.
-
公开(公告)号：US12170484B2
公开(公告)日：2024-12-17
申请号：US18592043
申请日：2024-02-29
Applicant: The Regents of the University of California
Inventor： Nathan Miles Ellis
Abstract: A Cockcroft-Walton (CW) switching voltage converter is disclosed. This CW switching converter includes a set of capacitors; an inductor coupled between an input voltage source and the set of capacitors; a set of switches; and an N-phase control module coupled to the set of switches. In some embodiments, each switch is controlled by the N-phase control module which is configured to sequentially and periodically effectuate a set of N voltage-conversion phases in a sequence of switching cycles. Note that each switching cycle effectuates a voltage conversion through the set of N voltage-conversion phases, wherein N is the conversion ratio of the CW switching voltage converter. Moreover, the N-phase control module is configured to effectuate a phase transition from a current phase to a subsequent phase when a zero-current switching (ZCS) condition on a given switch is met.
-
公开(公告)号：US12168144B2
公开(公告)日：2024-12-17
申请号：US17864281
申请日：2022-07-13
Inventor： Jes Broeng , Paul Michael Petersen , Ngoc Mai Thi Nguyen , Lance Kriegsfeld
IPC: A61N5/06
Abstract: In certain embodiments a light therapy system (e.g., phototherapy device), such as for treatment of Alzheimer's disease, depression, dementia, short-term memory, or for improved learning, improved athletic performance or improved cognitive performance, is provided where the light system comprises a blue light source that operates at a frequency in the range from 20 to 50 Hz (preferably around 40 Hz), whereby the system enables retinal ganglion cells of a human to be exposed in order to stimulate brain waves (gamma oscillations in the human's brain).
-
129.发明申请公开(公告)号：US20240410662A1
公开(公告)日：2024-12-12
申请号：US18771285
申请日：2024-07-12
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Vinod NARAYANAN , Erfan RASOULI
Abstract: Designs and applications of a polymer heat exchanger that includes a set of polymer plates with internal flow passages configured to carry a first gas or liquid. The set of plates is organized into a stack, wherein consecutive plates in the stack are separated by fins to form intervening flow passages for a second gas or liquid. The system includes a first liquid or gas flow pathway, which flows from an inlet, through the internal flow passages, to a first liquid or gas outlet. It also includes a second liquid or gas flow pathway, which flows from an inlet, through the intervening second gas or liquid passages, to an outlet. The first liquid or gas flow pathway flows in a direction opposite to a direction of the second liquid or gas flow pathway to provide a counterflow design that optimizes heat transfer between the two flow pathways.
-
公开(公告)号：US20240409895A1
公开(公告)日：2024-12-12
申请号：US18424086
申请日：2024-01-26
Applicant: The United States Government As Represented By The Department Of Veterans Affairs , The Regents Of The University Of California
Inventor： Robert L. Raffai , Tuan Anh Phu , Ngan Khanh Vu , Martin Ng , Laura Bouchareychas
IPC: C12N5/0786
Abstract: Disclosed are method of producing IL-4 exposed M2 macrophage exosomes comprising culturing macrophage or macrophage precursor cells with IL-4 in culture media, and isolating exosomes from the culture media, wherein the isolated exosomes are IL-4 exposed M2 macrophage exosomes enriched with miR-21, miR-99a, miR-146b and miR378a. Disclosed are methods of reprogramming macrophages and/or adipocytes comprising exposing the macrophages and/or adipocytes to IL-4 exposed M2 macrophage exosomes, wherein immune and/or metabolic properties are altered in the macrophages and/or adipocytes. Methods of treating with IL-4 exposed M2 macrophage exosomes.
-
-
-
-
-
-
-
-
-
Search Results
15797
records
(took 0.065 seconds)
