公开(公告)号：US20050220717A1

公开(公告)日：2005-10-06

申请号：US11061529

申请日：2005-02-22

申请人： Zheng Wu ,  Nayna Govind ,  Peter Johnson

发明人： Zheng Wu ,  Nayna Govind ,  Peter Johnson

IPC分类号： A61K9/00 ,  A61K9/12 ,  A61K31/57 ,  A61K31/573 ,  A61K31/58 ,  A61K47/06 ,  A61K47/10 ,  A61L9/04 ,  A61M11/00 ,  B65D83/14

CPC分类号： A61K9/008 ,  A61K9/124 ,  A61K31/57 ,  A61K31/573 ,  A61K31/58 ,  B65D83/38 ,  B65D83/54

摘要： A medicinal aerosol steroid solution formulation product with enhanced chemical stability. The steroid is a 20-ketosteroid having an OH group at the C-17 or C-21 position and the aerosol container has a non-metal interior surface which has been found to reduce chemical degradation of such steroids.

摘要翻译： 具有增强化学稳定性的药用气溶胶类固醇溶液制剂产品。 类固醇是在C-17或C-21位置具有OH基团的20-酮类固醇，并且气溶胶容器具有非金属内表面，已被发现可减少这类类固醇的化学降解。

公开(公告)号：US06874596B2

公开(公告)日：2005-04-05

申请号：US10244794

申请日：2002-09-16

申请人： Brett Richard Zeissler ,  Peter Johnson

发明人： Brett Richard Zeissler ,  Peter Johnson

IPC分类号： A62B35/00 ,  A47L3/04

CPC分类号： A62B35/0018 ,  A62B35/00 ,  A62B35/0037

摘要： A safety harness with a front D-ring includes an upper body portion and a lower body portion. A front D-ring is positioned at a front of the upper body portion where a first shoulder strap and a second shoulder strap cross. A single length of webbing is used to form a first end of the first shoulder strap, form a first end of the second shoulder strap and connect the front D-ring in a fixed position relative to the first shoulder strap and the second shoulder strap. The single length of webbing is wrapped around a cross-piece of the front D-ring and the first end of the first shoulder strap is formed from a first loop of the single length of webbing sewn together and the second end of the second shoulder strap is formed from a second loop of the single length of webbing sewn together.

摘要翻译： 具有前D形环的安全带包括上主体部分和下主体部分。 前D形环位于第一肩带和第二肩带交叉的上身部分的前部。 使用单个长度的织带来形成第一肩带的第一端，形成第二肩带的第一端，并将前D形环相对于第一肩带和第二肩带连接在固定位置。 单个长度的织带缠绕在前D形环的横截面上，并且第一肩带的第一端由缝合在一起的单个织带的第一环和第二肩带的第二端形成 由缝制在一起的单一织带的第二环形成。

公开(公告)号：US06799718B2

公开(公告)日：2004-10-05

申请号：US10193647

申请日：2002-07-10

申请人： Ken Chan ,  Hin Boen ,  Peter Johnson ,  Campegius L. Bronkhorst

发明人： Ken Chan ,  Hin Boen ,  Peter Johnson ,  Campegius L. Bronkhorst

IPC分类号： G06F1700

CPC分类号： G06F8/33

摘要： Development assistance for a program comprising code in more than one language, is provided appropriately for each language in an integrated development environment. The assistance can include syntax highlighting, structure analysis, error reporting, completion assistance and/or context-sensitive help. The language of the subject element of code is determined and the appropriate assistance processes are applied. If the code is in a supplementary language, routines associated with the supplementary language are invoked to provide the assistance. When needed, information from other parts of the program file is provided to determine the appropriate assistance for the element of code.

摘要翻译： 对于包含多种语言的代码的程序的开发帮助，适用于集成开发环境中的每种语言。 帮助可以包括语法高亮，结构分析，错误报告，完成帮助和/或上下文相关帮助。 确定代码主题元素的语言并应用适当的辅助过程。 如果代码是补充语言，则调用与补充语言相关联的例程以提供帮助。 当需要时，提供来自程序文件其他部分的信息，以确定代码元素的适当帮助。

公开(公告)号：US06740956B1

公开(公告)日：2004-05-25

申请号：US10219896

申请日：2002-08-15

申请人： Peter J. Hopper ,  Peter Johnson ,  Kyuwoon Hwang ,  Michael Mian ,  Robert Drury

发明人： Peter J. Hopper ,  Peter Johnson ,  Kyuwoon Hwang ,  Michael Mian ,  Robert Drury

IPC分类号： H01L2900

CPC分类号： H01L23/5227 ,  H01L23/5283 ,  H01L2924/0002 ,  H01L2924/3011 ,  H01L2924/00

摘要： The RF impedance of a metal trace at gigahertz frequencies is reduced by forming the metal trace to have a base region and a number of fingers that extend away from the base region. When formed to have a number of loops, the metal trace forms an inductor with an increased Q.

摘要翻译： 以千兆赫兹频率的金属迹线的RF阻抗通过形成金属迹线而减小，以具有从基极区域延伸的基极区域和多个指状物。 当形成为具有多个环时，金属迹线形成具有增加的Q的电感器。

公开(公告)号：US06453324B1

公开(公告)日：2002-09-17

申请号：US09539260

申请日：2000-03-30

申请人： Donald Edward Baisley ,  Peter Johnson

发明人： Donald Edward Baisley ,  Peter Johnson

IPC分类号： G06F1730

CPC分类号： G06F17/30607 ,  Y10S707/99954

摘要： An improved computer-implemented method is disclosed, which maintains a version history of objects in a repository. Modifications to property values and links are tracked with respect to versions of a model. The method includes the steps of maintaining a start version and a list of end versions for each object in the model and maintaining a start version and a list of end versions for each attribute value in the model. Moreover, in response to a request for objects in a class with respect to a current version, only those objects whose start version is in the history of the current version and whose end versions are not in the history of the current version are retrieved. Also, in response to a request for attribute values of an object with respect to a current version, only those values whose start version is in the history of the current version and whose end versions are not in the history of the current version are retrieved.

摘要翻译： 公开了一种改进的计算机实现的方法，其维护存储库中的对象的版本历史。 关于模型的版本跟踪属性值和链接的修改。 该方法包括以下步骤：维护模型中每个对象的起始版本和最终版本列表，并维护模型中每个属性值的起始版本和最终版本列表。 此外，响应于针对当前版本的类中的对象的请求，仅检索起始版本在当前版本的历史中并且其最终版本不在当前版本的历史中的那些对象。 此外，响应于对当前版本的对象的属性值的请求，仅检索起始版本在当前版本的历史中并且其最终版本不在当前版本的历史中的那些值。

公开(公告)号：US5878056A

公开(公告)日：1999-03-02

申请号：US822974

申请日：1997-03-21

申请人： George Black ,  Peter Johnson

发明人： George Black ,  Peter Johnson

IPC分类号： H04L1/18 ,  H04L1/14

CPC分类号： H04L1/1835 ,  H04L1/1809

摘要： Provided are methods and systems for message transfer between nodes of a communication network which reduce the occurrence of repeated transfer failures associated with a particular message or messages within a batch. When a batch of messages sent from a sender node cannot be stored at a receiver node, the receiver node identifies which messages within the batch caused the rejection and communicates this information to the sender node. The sender node records the destinations of the identified messages in a "destination black list", and then separates messages having these identified problematic destinations from the other messages. The batch of messages is then retransmitted to the receiver, but with the messages which have the identified problematic destinations excluded from the batch. These excluded messages are then dealt with separately without causing repeated rejection of the batch.

摘要翻译： 提供了用于在通信网络的节点之间的消息传送的方法和系统，其减少与批次内的特定消息或消息相关联的重复传送故障的发生。 当从发送方节点发送的一批消息不能存储在接收方节点时，接收方节点识别批中的哪些消息导致拒绝，并将该信息传送给发送方节点。 发送者节点将所识别的消息的目的地记录在“目的地黑名单”中，然后将具有这些识别的有问题的目的地的消息与其他消息分离。 然后将批次的消息重新发送到接收器，但是具有从批次中排除的识别的有问题的目的地的消息。 然后，这些排除的消息将分开处理，而不会导致批次的重复拒绝。

公开(公告)号：US5756550A

公开(公告)日：1998-05-26

申请号：US708500

申请日：1996-09-05

申请人： Peter Johnson ,  Barry E. Watkins ,  Eric W. Harris

发明人： Peter Johnson ,  Barry E. Watkins ,  Eric W. Harris

IPC分类号： A61K31/165 ,  A61K31/195

CPC分类号： A61K31/195 ,  A61K31/165

摘要： 2-Amino-N-(1,2-diphenyl-1-methylethyl) acetamide (remacemide), or a pharmaceutically acceptable salt thereof, for use in the treatment of Parkinson's disease is disclosed.

摘要翻译： 公开了用于治疗帕金森病的2-氨基-N-（1,2-二苯基-1-甲基乙基）乙酰胺（remacemide）或其药学上可接受的盐。

公开(公告)号：US5644764A

公开(公告)日：1997-07-01

申请号：US382303

申请日：1995-01-31

申请人： Peter Johnson ,  Sridhar Srinivasa Iyengar

发明人： Peter Johnson ,  Sridhar Srinivasa Iyengar

IPC分类号： G06F12/00 ,  G06F17/30

CPC分类号： G06F17/30607 ,  Y10S707/99944 ,  Y10S707/99953

摘要： In a computer system having a user interface, a memory, a repository and a database, a repository program operating in the computer system for accessing the database, the repository program executing a method for supporting modeling, the method comprising the steps of examining a collection of types forming a model; sorting object types into data and persistent type objects; creating all data type objects and adding to a collection of all objects owned by the model; creating all persistent type objects and adding to a collection of all objects owned by the model; initializing all persistent type objects in the collection of objects.

摘要翻译： 在具有用户接口，存储器，存储库和数据库的计算机系统中，在计算机系统中操作用于访问数据库的存储库程序，执行支持建模的方法的存储库程序，该方法包括以下步骤： 形成模型; 将对象类型分类为数据和持久类型对象; 创建所有数据类型对象并添加到模型所拥有的所有对象的集合中; 创建所有持久类型对象并添加到模型所拥有的所有对象的集合中; 初始化对象集合中的所有持久类型对象。

公开(公告)号：US10525129B2

公开(公告)日：2020-01-07

申请号：US13817744

申请日：2011-08-19

申请人： Mark Cragg ,  Martin Glennie ,  Ali Roghanian ,  Stephen Beers ,  Peter Johnson ,  Sean Lim ,  Bjorn Frendeus ,  Ingrid Teige

发明人： Mark Cragg ,  Martin Glennie ,  Ali Roghanian ,  Stephen Beers ,  Peter Johnson ,  Sean Lim ,  Bjorn Frendeus ,  Ingrid Teige

IPC分类号： A61K39/395 ,  A61K39/40 ,  C07K16/28 ,  G01N33/68 ,  C07K16/00 ,  A61K39/00

摘要： The invention provides a method of treating a patient having target cells that express FcyRIIb, the method comprising administering (i) an antibody molecule that specifically binds a surface antigen of the target cell, which antibody molecule has an Fc domain capable of binding FcyRIIb; in combination with (ii) an agent that prevents or reduces binding between the Fc domain of the antibody molecule and FcyRIIb; characterized in that the patient is selected on the basis that their target cells express an elevated level of FcyRIIb.

公开(公告)号：US09428464B2

公开(公告)日：2016-08-30

申请号：US14241699

申请日：2012-08-28

申请人： Stephen Martin Courtney ,  Michael Prime ,  William Mitchell ,  Christopher John Brown ,  Paula C. De Aguiar Pena ,  Peter Johnson ,  Celia Dominguez ,  Leticia M. Toledo-Sherman ,  Ignacio Muñoz-Sanjuan

发明人： Stephen Martin Courtney ,  Michael Prime ,  William Mitchell ,  Christopher John Brown ,  Paula C. De Aguiar Pena ,  Peter Johnson ,  Celia Dominguez ,  Leticia M. Toledo-Sherman ,  Ignacio Muñoz-Sanjuan

IPC分类号： C07D239/52 ,  A61K31/506 ,  C07D239/28 ,  C07D403/12 ,  C07D403/06 ,  C07D405/12 ,  C07D413/12 ,  C07D491/048 ,  C07D239/42 ,  C07D401/04 ,  C07D401/12 ,  C07D417/12 ,  C07D471/04 ,  C07D487/04

CPC分类号： C07D239/28 ,  A61K31/506 ,  C07D239/42 ,  C07D239/52 ,  C07D401/04 ,  C07D401/12 ,  C07D403/06 ,  C07D403/12 ,  C07D405/12 ,  C07D413/12 ,  C07D417/12 ,  C07D471/04 ,  C07D487/04 ,  C07D491/048 ,  Y02A50/401 ,  Y02A50/411 ,  Y02A50/465

摘要： Certain chemical entities are provided herein. Also provided are pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one chemical entity as a single active agent or administering at least one chemical entity in combination with one or more other therapeutic agents. Also provided are methods for screening compounds capable of inhibiting KMO activity.

摘要翻译： 本文提供了某些化学实体。 还提供了包含至少一种化学实体和一种或多种药学上可接受的载体的药物组合物。 描述了治疗患有对KMO活性的抑制作用的某些疾病和病症的患者的方法，其包括给予这些患者一定量的至少一种有效减少疾病或病症的体征或症状的化学实​​体。 这些疾病包括神经变性疾病如亨廷顿氏病。 还描述了治疗方法，包括给予至少一种作为单一活性剂的化学实体或与一种或多种其它治疗剂组合施用至少一种化学实体。 还提供了用于筛选能够抑制KMO活性的化合物的方法。