Organic semiconductor inverting circuit
    132.
    发明授权
    Organic semiconductor inverting circuit 失效
    有机半导体反相电路

    公开(公告)号:US07030666B2

    公开(公告)日:2006-04-18

    申请号:US10788627

    申请日:2004-02-27

    IPC分类号: H03B1/00 H03K3/00

    CPC分类号: H03K19/08

    摘要: An organic semiconductor inverting circuit includes at least three organic transistors, an output terminal (110, 210, 310, 410), a reference supply voltage input (115, 215, 315, 415), a first positive supply voltage input (120, 220, 320, 420), and a negative supply voltage input (125, 225, 325, 425). One of the three organic transistors is an input transistor having a gate to which is coupled an input terminal (105, 205, 305, 405). The output terminal (110, 210, 310, 410) is coupled to a first electrode of at least one of the at least three organic transistors.

    摘要翻译: 有机半导体反相电路包括至少三个有机晶体管,输出端(110,210,310,410),参考电源电压输入(115,215,315,415),第一正电源电压输入端(120,220) ,320,420)和负电源电压输入(125,225,325,425)。 三个有机晶体管中的一个是具有与输入端(105,205,305,405)耦合的栅极的输入晶体管。 输出端子(110,210,310,410)耦合到至少三个有机晶体管中的至少一个的第一电极。

    Extended release formulations of erythromycin derivatives
    133.
    发明申请
    Extended release formulations of erythromycin derivatives 审中-公开
    红霉素衍生物的延长释放制剂

    公开(公告)号:US20060039969A1

    公开(公告)日:2006-02-23

    申请号:US11091637

    申请日:2005-03-28

    IPC分类号: A61K9/20 A61K31/7048

    摘要: Disclosed is a pharmaceutical composition for extended release of an erythromycin derivative in the gastrointestinal environment. The composition comprises an erythromycin derivative and a pharmaceutically acceptable polymer so that, when ingested orally, the composition induces statistically significantly lower Cmax in the plasma than an immediate release composition of the erythromycin derivative while maintaining bioavailability and minimum concentration substantially equivalent to that of the immediate release composition of the erythromycin derivative upon multiple dosing. The compositions of the invention have an improved taste profile and reduced gastrointestinal side effects as compared to those for the immediate release composition.

    摘要翻译: 公开了用于在胃肠环境中延长释放红霉素衍生物的药物组合物。 该组合物包含红霉素衍生物和药学上可接受的聚合物,使得当口服摄入时,组合物在血浆中诱导统计学显着降低红霉素衍生物的立即释放组合物,同时保持生物利用度和最小值 浓度基本上等同于多次给药时红霉素衍生物的速释组合物。 与立即释放组合物相比,本发明的组合物具有改善的味道特征和降低的胃肠道副作用。

    Monitoring stability of an on-frequency repeater
    134.
    发明申请
    Monitoring stability of an on-frequency repeater 审中-公开
    监控频率中继器的稳定性

    公开(公告)号:US20060034351A1

    公开(公告)日:2006-02-16

    申请号:US10917385

    申请日:2004-08-13

    IPC分类号: H04B1/707 H04L25/52

    摘要: In a system for monitoring stability of an on-frequency repeater, a wide-band signature (WBS) signal associated with the repeater is generated, and inserted into an output RF signal transmitted by the repeater. Signal components corresponding to the WBS signal in an input RF signal received by the repeater are detected and analyzed to estimate a feedback path loss L.

    摘要翻译: 在用于监视频率中继器的稳定性的系统中,生成与中继器相关联的宽带签名(WBS)信号,并将其插入到由中继器发送的输出RF信号中。 检测并分析由中继器接收的输入RF信号中与WBS信号对应的信号分量,以估计反馈路径损耗L.

    E2F oligonucleotide decoy molecules
    136.
    发明申请
    E2F oligonucleotide decoy molecules 审中-公开
    E2F寡核苷酸诱饵分子

    公开(公告)号:US20050164240A1

    公开(公告)日:2005-07-28

    申请号:US10960165

    申请日:2004-10-06

    IPC分类号: A61K38/00 C12N15/113 C12Q1/68

    摘要: The invention concerns E2F oligonucleotide decoy molecules with improved properties. In particular, the invention concerns a double-stranded E2F decoy oligodeoxynucleotide (dsODN) molecule comprising a core sequence that is capable of specific binding to an E2F transcription factor, flanked by 5′ and 3′ sequences, wherein (i) the core sequence consists of about 5 to 12 base pairs; (ii) the molecule comprises an about 12 to 28 base-pair long double-stranded region composed of two fully complementary strands; and (iii) the E2F dsODN binds to said E2F transcription factor with a binding affinity that is at least about 5-fold of the binding affinity of a reference decoy molecule shown in FIG. 1 (SEQ ID NOS: 1 and 2), as determined by a competitive gel mobility shift binding assay performed on nuclear extract from THP-1 cells.

    摘要翻译: 本发明涉及具有改进性质的E2F寡核苷酸诱饵分子。 特别地,本发明涉及双链E2F诱饵寡脱氧核苷酸(dsODN)分子,其包含能够与侧翼为5'和3'序列的E2F转录因子特异性结合的核心序列,其中(i)核心序列组成 约5至12个碱基对; (ii)分子包含由两个完全互补的链组成的约12至28个碱基对长双链区域; 和(iii)E2F dsODN以与图1所示的参考诱饵分子的结合亲和力的至少约5倍的结合亲和力结合所述E2F转录因子。 1(SEQ ID NO:1和2),其通过对来自THP-1细胞的核提取物进行的竞争性凝胶迁移率转移结合测定法测定。

    Organic semiconductor and method
    140.
    发明授权
    Organic semiconductor and method 失效
    有机半导体和方法

    公开(公告)号:US06603141B2

    公开(公告)日:2003-08-05

    申请号:US10034337

    申请日:2001-12-28

    IPC分类号: H01L2700

    摘要: A semiconductor device formed of a flexible or rigid substrate (10) having a gate electrode (11), a source electrode (12), and a drain electrode (13) formed thereon and organic semiconductor material (14) disposed at least partially thereover. With appropriate selection of material, the gate electrode (11) will form a Schottky junction and an ohmic contact will form between the organic semiconductor material (14) and each of the source electrode (12) and drain electrode (13). In many of the embodiments, any of the above elements can be formed through contact or non-contact printing. Sizing of the resultant device can be readily scaled to suit various needs.

    摘要翻译: 由具有形成在其上的栅电极(11),源电极(12)和漏电极(13)的柔性或刚性基板(10)形成的半导体器件和至少部分地设置在其上的有机半导体材料(14)构成。 通过适当选择材料,栅电极(11)将形成肖特基结,在有机半导体材料(14)与源电极(12)和漏电极(13)之间形成欧姆接触。 在许多实施例中,可以通过接触或非接触印刷形成任何上述元件。 可以容易地缩放所得到的装置的尺寸以适应各种需要。