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    Drug-eluting stent cover method of use
    132.
    发明授权
    Drug-eluting stent cover method of use 有权
    药物洗脱支架覆盖法使用

    公开(公告)号：US07413574B2

    公开(公告)日：2008-08-19

    申请号：US11497652

    申请日：2006-08-01

    Applicant: Philip S. Yip ,  James Jacobs ,  Syed Hossainy ,  Jon Becker ,  Timothy A. Limon

    Inventor： Philip S. Yip ,  James Jacobs ,  Syed Hossainy ,  Jon Becker ,  Timothy A. Limon

    IPC: A61F2/06

    CPC classification number: A61F2/91 ,  A61F2/90 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2250/0036 ,  A61F2250/0067 ,  A61F2250/0071 ,  Y10S623/903

    Abstract: An intravascular stent includes an eluting sheath fabricated from a mesh for controlled release of therapeutic drugs and for delivery of the therapeutic drugs in localized drug therapy in a blood vessel. The eluting sheath is attached to at least a portion of an outside surface area of the stent structure and is fabricated from a mesh designed to neck down in response to a radially outward directed force resulting in the uniform expansion of the stent. The eluting sheath can be loaded with at least one therapeutic drug for the release thereof at a treatment site to facilitate repair of a damaged vessel. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen.

    Abstract translation: 血管内支架包括由用于控制释放治疗药物的网格和用于在血管中局部药物治疗中递送治疗药物的筛网制成的洗脱鞘。 洗脱鞘附着到支架结构的外表面区域的至少一部分上，并且由设计成颈部向下的网眼制成，以适应径向向外的力，导致支架的均匀膨胀。 洗脱鞘可以装载至少一种用于在治疗部位释放的治疗药物，以便于修复受损血管。 支架在纵向具有高度的柔性，但具有足够的容器壁覆盖和径向强度足以保持打开动脉或其他体腔。

    Bioabsorbable, biobeneficial polyester polymers for stent coatings
    137.
    发明申请
    Bioabsorbable, biobeneficial polyester polymers for stent coatings 有权
    用于支架涂层的生物可吸收，生物有益的聚酯聚合物

    公开(公告)号：US20070100123A1

    公开(公告)日：2007-05-03

    申请号：US11643331

    申请日：2006-12-20

    Applicant: Syed Hossainy ,  Stephen Pacetti

    Inventor： Syed Hossainy ,  Stephen Pacetti

    IPC: C08G63/02

    CPC classification number: A61L31/06 ,  A61L27/18 ,  C08G63/20 ,  C08G63/668 ,  C08G63/6854 ,  C08G63/6886 ,  C08L67/02 ,  C08L67/025 ,  C08L67/04 ,  C08L69/00 ,  C08L73/02 ,  C08L2666/20 ,  C08L2666/18

    Abstract: This disclosure covers polymers, some of which are useful in medical device applications. Some of these medical devices are implantable within a mammalian body, such as in a body lumen. The copolymers comprise at least one alcoholic moiety derived from a diol, triol, or polyol. Additionally, the copolymers comprise an acidic moiety, derived from a polycarboxylic acid, and a biobeneficial moiety. Some of these copolymers are biodegradable or bioerodable. Medical devices comprising these polymers and methods of making these polymers are within the scope of this disclosure.

    Abstract translation: 本公开内容涵盖聚合物，其中一些在医疗器械应用中是有用的。 这些医疗装置中的一些可植入哺乳动物体内，例如在体腔中。 共聚物包含至少一种衍生自二醇，三醇或多元醇的醇部分。 另外，共聚物包含衍生自多元羧酸的酸性部分和生物有益部分。 这些共聚物中的一些是可生物降解的或可生物侵蚀的。 包含这些聚合物的医疗装置和制备这些聚合物的方法在本公开的范围内。

    Drug-eluting stent cover and method of use
    139.
    发明申请
    Drug-eluting stent cover and method of use 有权
    药物洗脱支架盖及使用方法

    公开(公告)号：US20070073383A1

    公开(公告)日：2007-03-29

    申请号：US11497706

    申请日：2006-08-01

    Applicant: Philip Yip ,  James Jacobs ,  Syed Hossainy ,  Jon Becker ,  Timothy Limon

    Inventor： Philip Yip ,  James Jacobs ,  Syed Hossainy ,  Jon Becker ,  Timothy Limon

    IPC: A61F2/90

    CPC classification number: A61F2/91 ,  A61F2/90 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2250/0036 ,  A61F2250/0067 ,  A61F2250/0071 ,  Y10S623/903

    Abstract: An intravascular stent includes an eluting sheath fabricated from a mesh for controlled release of therapeutic drugs and for delivery of the therapeutic drugs in localized drug therapy in a blood vessel. The eluting sheath is attached to at least a portion of an outside surface area of the stent structure and is fabricated from a mesh designed to neck down in response to a radially outward directed force resulting in the uniform expansion of the stent. The eluting sheath can be loaded with at least one therapeutic drug for the release thereof at a treatment site to facilitate repair of a damaged vessel. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen.

    Abstract translation: 血管内支架包括由用于控制释放治疗药物的网格和用于在血管中局部药物治疗中递送治疗药物的筛网制成的洗脱鞘。 洗脱鞘附着到支架结构的外表面区域的至少一部分上，并且由设计成颈部向下的网眼制成，以适应径向向外的力，导致支架的均匀膨胀。 洗脱鞘可以装载至少一种用于在治疗部位释放的治疗药物，以便于修复受损血管。 支架在纵向具有高度的柔性，但具有足够的容器壁覆盖和径向强度足以保持打开动脉或其他体腔。

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