公开(公告)号：US08688486B2

公开(公告)日：2014-04-01

申请号：US11777571

申请日：2007-07-13

Applicant: John Daniel Griffin

Inventor： John Daniel Griffin

IPC: G06Q10/00

CPC classification number: H04M3/5233 ,  G06Q10/063112 ,  H04M3/5238 ,  H04M2203/405

Abstract: System, method and program product for dynamically setting a wage offered to a multiplicity of inactive call center personnel. First program instructions automatically estimate a wait time for calls to a call center. The calls are handled by a plurality of active call center personnel. Second program instructions automatically determine and set a wage, based in part on the estimated wait time, offered to inactive call center personnel to induce them to become active call center personnel to handle calls. Third program instructions, responsive to a request by an inactive call center person to become active at said wage, automatically designate the requesting inactive call center person as active at the wage and assign a call to the requesting inactive call center personnel that was designated as active. Program instructions also set a renewal wage paid to active call center personnel, based in part on the estimated wait time, to induce the active call center personnel to remain active.

Abstract translation: 系统，方法和程序产品，用于动态设置提供给多个无效呼叫中心人员的工资。 第一程序指令自动估计呼叫中心呼叫的等待时间。 呼叫由多个主动呼叫中心人员处理。 第二个程序指令自动确定并设置工资，部分基于估计的等待时间，提供给非活动呼叫中心人员，以诱使他们成为主动呼叫中心人员来处理呼叫。 第三程序指令响应于非活动呼叫中心人员以所述工资激活的请求，自动将请求的不活动呼叫中心人员指定为工资活动，并向被指定为活动的请求的非活动呼叫中心人员分配呼叫 。 程序指令还设置了一个支付给主动呼叫中心人员的更新工资，其部分原因是估计的等待时间，以引起主动呼叫中心人员保持活跃。

公开(公告)号：US08597687B2

公开(公告)日：2013-12-03

申请号：US13569095

申请日：2012-08-07

Applicant: John Daniel

Inventor： John Daniel

IPC: A61K35/50

CPC classification number: A61K35/50 ,  A61F2/02 ,  A61J1/00 ,  A61L27/3604 ,  A61L27/3683 ,  A61L27/3687 ,  A61L27/3691 ,  A61L27/3695 ,  A61L27/40 ,  A61L27/50 ,  A61L27/54 ,  A61L27/58 ,  A61L2300/412 ,  A61L2300/60 ,  A61L2300/64 ,  A61L2430/40 ,  B65D25/205 ,  B65D81/18 ,  B65D85/70

Abstract: A method for preparing placenta membrane tissue grafts for medical use, includes obtaining a placenta from a subject, cleaning the placenta, separating the chorion tissue from the amniotic membrane, mounting a selected layer of either the chorion tissue or the amniotic membrane onto a drying fixture, dehydrating the selected layer on the drying fixture, and cutting the selected layer into a plurality of tissue grafts. Preferably, the drying fixture includes grooves or raised edges that define the outer contours of each desired tissue graft, after they are cut, and further includes raised or indented logos that emboss the middle area of the tissue grafts during dehydration and that enables an end user to distinguish the top from the bottom side of the graft. The grafts are comprised of single layers of amnion or chorion, multiple layers of amnion or chorion, or multiple layers of a combination of amnion and chorion.

Abstract translation: 一种用于制备用于医疗用途的胎盘膜组织移植物的方法，包括从受试者获得胎盘，清洁胎盘，将绒毛膜组织与羊膜分离，将选定的绒毛膜组织或羊膜安装在干燥装置上 使干燥夹具上的所选层脱水，将所选择的层切割成多个组织移植物。 优选地，干燥夹具包括凹槽或凸起边缘，其限定每个期望的组织移植物在其切割之后的外部轮廓，并且还包括在脱水期间压印组织移植物的中间区域的凸起或凹入的标识，并且使最终使用者 以区分顶部与移植物的底侧。 移植物由单层羊膜或绒毛膜，多层羊膜或绒毛膜组成，或多层羊膜和绒毛膜组合。

公开(公告)号：US20130224159A1

公开(公告)日：2013-08-29

申请号：US13861305

申请日：2013-04-11

Applicant: John Daniel ,  Randall Spencer

Inventor： John Daniel ,  Randall Spencer

IPC: A61K35/12

CPC classification number: A61K35/28 ,  A61F2/02 ,  A61F2210/00 ,  A61F2230/00 ,  A61K9/7007 ,  A61K35/19 ,  A61K35/33 ,  A61K35/50 ,  A61L27/3604 ,  A61L27/3683 ,  A61L27/3834 ,  A61L27/56 ,  A61L2430/34 ,  A61L2430/40 ,  Y10T156/10 ,  Y10T156/1039

Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.

Abstract translation: 这里描述的是来自胎盘的组织移植物。 移植物由至少一层羊膜组织组成，其中已经基本上去除了上皮层，以便将基底层暴露于宿主细胞。 通过去除上皮层，来自宿主的细胞可以更容易地与位于基底膜顶部和内部的细胞粘附生物活性因子相互作用。 本文还描述了用于制造和使用组织移植物的方法。 羊膜组织的层粘连蛋白结构与天然人体组织例如口腔粘膜组织几乎相同。 这包括高水平的层粘连蛋白-5，细胞粘附生物活性因子显示结合牙龈上皮细胞，遍及基底膜的上部。

公开(公告)号：US08487390B2

公开(公告)日：2013-07-16

申请号：US12418911

申请日：2009-04-06

Applicant: Dimitar V. Dimitrov ,  Ivan Petrov Ivanov ,  Shuiyuan Huang ,  Antoine Khoueir ,  Brian Lee ,  John Daniel Stricklin ,  Olle Gunnar Heinonen ,  Insik Jin

Inventor： Dimitar V. Dimitrov ,  Ivan Petrov Ivanov ,  Shuiyuan Huang ,  Antoine Khoueir ,  Brian Lee ,  John Daniel Stricklin ,  Olle Gunnar Heinonen ,  Insik Jin

IPC: H01L29/82 ,  G11C11/14

CPC classification number: G11C11/1675 ,  G11C11/161

Abstract: A magnetic memory element that has a stress-induced magnetic anisotropy. The memory element has a ferromagnetic free layer having a switchable magnetization orientation switchable, a ferromagnetic reference layer having a pinned magnetization orientation, and a non-magnetic spacer layer therebetween. The free layer may be circular, essentially circular or nearly circular.

Abstract translation: 具有应力诱导的磁各向异性的磁记忆元件。 存储元件具有可切换的磁化方向可转换的铁磁自由层，具有钉扎​​磁化取向的铁磁参考层和它们之间的非磁性间隔层。 自由层可以是圆形的，基本上是圆形的或近似圆形的。

公开(公告)号：US08460716B2

公开(公告)日：2013-06-11

申请号：US13569131

申请日：2012-08-07

Applicant: John Daniel

Inventor： John Daniel

IPC: A61K35/50

CPC classification number: A61K35/50 ,  A61F2/02 ,  A61J1/00 ,  A61L27/3604 ,  A61L27/3683 ,  A61L27/3687 ,  A61L27/3691 ,  A61L27/3695 ,  A61L27/40 ,  A61L27/50 ,  A61L27/54 ,  A61L27/58 ,  A61L2300/412 ,  A61L2300/60 ,  A61L2300/64 ,  A61L2430/40 ,  B65D25/205 ,  B65D81/18 ,  B65D85/70

Abstract: A method for preparing placenta membrane tissue grafts for medical use, includes obtaining a placenta from a subject, cleaning the placenta, separating the chorion tissue from the amniotic membrane, mounting a selected layer of either the chorion tissue or the amniotic membrane onto a drying fixture, dehydrating the selected layer on the drying fixture, and cutting the selected layer into a plurality of tissue grafts. Preferably, the drying fixture includes grooves or raised edges that define the outer contours of each desired tissue graft, after they are cut, and further includes raised or indented logos that emboss the middle area of the tissue grafts during dehydration and that enables an end user to distinguish the top from the bottom side of the graft. The grafts are comprised of single layers of amnion or chorion, multiple layers of amnion or chorion, or multiple layers of a combination of amnion and chorion.

Abstract translation: 一种用于制备用于医疗用途的胎盘膜组织移植物的方法，包括从受试者获得胎盘，清洁胎盘，将绒毛膜组织与羊膜分离，将选定的绒毛膜组织或羊膜安装在干燥装置上 使干燥夹具上的所选层脱水，将所选择的层切割成多个组织移植物。 优选地，干燥夹具包括凹槽或凸起边缘，其限定每个期望的组织移植物在其切割之后的外部轮廓，并且还包括在脱水期间压印组织移植物的中间区域的凸起或凹入的标识，并且使最终使用者 以区分顶部与移植物的底侧。 移植物由单层羊膜或绒毛膜，多层羊膜或绒毛膜组成，或多层羊膜和绒毛膜组合。

公开(公告)号：US08378153B2

公开(公告)日：2013-02-19

申请号：US12734629

申请日：2008-11-07

Applicant: Berian John Daniel ,  Jon Michael Stewart Deeley ,  Benjamin Patrick Gracey ,  Cong Rong Li

Inventor： Berian John Daniel ,  Jon Michael Stewart Deeley ,  Benjamin Patrick Gracey ,  Cong Rong Li

IPC: C07C27/04

CPC classification number: C07C29/159 ,  C07C29/149 ,  C07C29/1518 ,  C07C51/12 ,  C07C67/08 ,  C23F14/02 ,  Y02P20/582 ,  C07C31/08 ,  C07C31/04 ,  C07C53/08 ,  C07C69/14

Abstract: The present invention relates to an improved process for the production of ethanol from a carbonaceous feedstock; wherein the carbonaceous feedstock is first converted to synthesis gas which is then converted to ethanoic acid, which is then esterified and which is then hydrogenated to produce ethanol.

Abstract translation: 本发明涉及一种用于从碳质原料生产乙醇的改进方法; 其中碳质原料首先转化为合成气，然后将其转化为乙酸，然后将其酯化，然后将其氢化生成乙醇。

公开(公告)号：US08323701B2

公开(公告)日：2012-12-04

申请号：US12428908

申请日：2009-04-23

Applicant: John Daniel ,  Robert Tofe ,  Randall Spencer ,  John Russo

Inventor： John Daniel ,  Robert Tofe ,  Randall Spencer ,  John Russo

IPC: A61K35/50

CPC classification number: A61K35/28 ,  A61F2/02 ,  A61F2210/00 ,  A61F2230/00 ,  A61K9/7007 ,  A61K35/19 ,  A61K35/33 ,  A61K35/50 ,  A61L27/3604 ,  A61L27/3683 ,  A61L27/3834 ,  A61L27/56 ,  A61L2430/34 ,  A61L2430/40 ,  Y10T156/10 ,  Y10T156/1039

Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.

Abstract translation: 这里描述的是来自胎盘的组织移植物。 移植物由至少一层羊膜组织组成，其中已经基本上去除了上皮层，以便将基底层暴露于宿主细胞。 通过去除上皮层，来自宿主的细胞可以更容易地与位于基底膜顶部和内部的细胞粘附生物活性因子相互作用。 本文还描述了用于制造和使用组织移植物的方法。 羊膜组织的层粘连蛋白结构与天然人体组织例如口腔粘膜组织几乎相同。 这包括高水平的层粘连蛋白-5，表现为结合牙龈上皮细胞的细胞粘附生物活性因子，其遍及基底膜的上部。

公开(公告)号：US20120294810A1

公开(公告)日：2012-11-22

申请号：US13569095

申请日：2012-08-07

Applicant: John Daniel

Inventor： John Daniel

IPC: A61K35/12

CPC classification number: A61K35/50 ,  A61F2/02 ,  A61J1/00 ,  A61L27/3604 ,  A61L27/3683 ,  A61L27/3687 ,  A61L27/3691 ,  A61L27/3695 ,  A61L27/40 ,  A61L27/50 ,  A61L27/54 ,  A61L27/58 ,  A61L2300/412 ,  A61L2300/60 ,  A61L2300/64 ,  A61L2430/40 ,  B65D25/205 ,  B65D81/18 ,  B65D85/70

Abstract: A method for preparing placenta membrane tissue grafts for medical use, includes obtaining a placenta from a subject, cleaning the placenta, separating the chorion tissue from the amniotic membrane, mounting a selected layer of either the chorion tissue or the amniotic membrane onto a drying fixture, dehydrating the selected layer on the drying fixture, and cutting the selected layer into a plurality of tissue grafts. Preferably, the drying fixture includes grooves or raised edges that define the outer contours of each desired tissue graft, after they are cut, and further includes raised or indented logos that emboss the middle area of the tissue grafts during dehydration and that enables an end user to distinguish the top from the bottom side of the graft. The grafts are comprised of single layers of amnion or chorion, multiple layers of amnion or chorion, or multiple layers of a combination of amnion and chorion.

Abstract translation: 一种用于制备用于医疗用途的胎盘膜组织移植物的方法，包括从受试者获得胎盘，清洁胎盘，将绒毛膜组织与羊膜分离，将选定的绒毛膜组织或羊膜安装在干燥装置上 使干燥夹具上的所选层脱水，将所选择的层切割成多个组织移植物。 优选地，干燥夹具包括凹槽或凸起边缘，其限定每个期望的组织移植物在其切割之后的外部轮廓，并且还包括在脱水期间压印组织移植物的中间区域的凸起或凹入的标识，并且使最终使用者 以区分顶部与移植物的底侧。 移植物由单层羊膜或绒毛膜，多层羊膜或绒毛膜组成，或多层羊膜和绒毛膜组合。

公开(公告)号：US08232988B2

公开(公告)日：2012-07-31

申请号：US11931919

申请日：2007-10-31

Applicant: Brian Philip Mathews ,  Benjamin David Cochran ,  Nitin Mohan ,  Jeffrey Richard Klug ,  John Daniel Schmier

Inventor： Brian Philip Mathews ,  Benjamin David Cochran ,  Nitin Mohan ,  Jeffrey Richard Klug ,  John Daniel Schmier

IPC: G06T15/00

CPC classification number: G06T19/20 ,  G06T2219/2016

Abstract: The present disclosure includes, among other things, systems, methods and program products for pre-computing image manipulations.

Abstract translation: 本公开包括用于预计算图像操作的系统，方法和程序产品。

公开(公告)号：US20120046257A1

公开(公告)日：2012-02-23

申请号：US13284741

申请日：2011-10-28

Applicant: John Daniel Dobak ,  Kenneth Walter Locke

Inventor： John Daniel Dobak ,  Kenneth Walter Locke

IPC: A61K31/58 ,  A61P3/04 ,  A61K31/573 ,  A61K31/137 ,  A61K31/167

CPC classification number: A61K9/0019 ,  A61K9/08 ,  A61K31/137 ,  A61K31/167 ,  A61K31/56 ,  A61K31/568 ,  A61K31/573 ,  A61K31/58 ,  A61K2300/00

Abstract: Provided herein are pharmaceutical formulations, methods, and systems for treating regional fat deposits and fat-related conditions and indications. Methods comprise administering a pharmaceutical formulation consisting essentially of a long-acting beta-2 adrenergic receptor agonist, for example, salmeterol, suitable for subcutaneous administration. Methods further comprise administering a pharmaceutical formulation that is suitable for subcutaneous injection comprising: (a) a lipophilic long-acting selective beta-2 adrenergic receptor agonist and/or glucocorticosteroid, or a salt, optical isomer, racemate, solvate, or polymorph thereof; and (b) at least one subcutaneously acceptable inactive ingredient.

Abstract translation: 本文提供了用于治疗局部脂肪沉积物和脂肪相关病症和适应症的药物制剂，方法和系统。 方法包括施用基本上由适于皮下给药的长效β-2肾上腺素能受体激动剂例如沙美特罗组成的药物制剂。 方法还包括施用适于皮下注射的药物制剂，其包含：（a）亲脂性长效选择性β-2肾上腺素能受体激动剂和/或糖皮质激素，或其盐，旋光异构体，外消旋体，溶剂化物或多晶型物; 和（b）至少一种皮下可接受的无活性成分。