公开(公告)号：US20180193197A1

公开(公告)日：2018-07-12

申请号：US15911895

申请日：2018-03-05

Applicant: MOR RESEARCH APPLICATIONS LTD.

Inventor： Ariel Margulis

IPC: A61F11/00 ,  A61F2/18

CPC classification number: A61F11/004 ,  A61F2/18 ,  A61F2002/183

Abstract: A method for repairing a perforation in a tympanic membrane comprising attaching a single patch to an undersurface of the tympanic membrane covering the perforation.

公开(公告)号：US09901299B2

公开(公告)日：2018-02-27

申请号：US15102588

申请日：2014-12-09

Applicant: Yeda Research and Development Co. Ltd. ,  Mor Research Applications Ltd.

Inventor： Lior Haviv ,  Noam Sobel ,  Amiram Catz ,  Itzhak Glass ,  Anton Plotkin ,  Aharon Weissbrod ,  Sagit Shushan

IPC: A61N1/00 ,  A61B5/00 ,  A61B5/087 ,  A61B5/11 ,  A61N1/36 ,  A61B5/0492 ,  A61B5/0488 ,  A61B5/08 ,  G06F3/01

CPC classification number: A61B5/4836 ,  A61B5/0488 ,  A61B5/0492 ,  A61B5/0806 ,  A61B5/0816 ,  A61B5/0823 ,  A61B5/087 ,  A61B5/1103 ,  A61B5/7282 ,  A61B5/7475 ,  A61N1/36003 ,  A61N1/3601 ,  A61N1/36014 ,  A61N1/36017 ,  G06F3/012

Abstract: A system for assisted coughing includes a first sensor for measuring a parameter which can indicate a closed glottis and producing a first signal, a processor for receiving the first signal, determining a state indicating the closed glottis and generating an instruction for a Functional Electric Stimulation (FES) controller based, at least in part, on the determining, and a FES controller for generating an electric stimulation signal.

公开(公告)号：US20170268070A1

公开(公告)日：2017-09-21

申请号：US15500104

申请日：2015-07-30

Applicant: MOR RESEARCH APPLICATIONS LTD.

Inventor： Smadar AVIGAD ,  Isaac YANIV ,  Keren SHICHRUR

IPC: C12Q1/68

CPC classification number: A61K31/7105 ,  A61K31/4025 ,  A61K39/3955 ,  C12N15/1137 ,  C12N2310/141 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/178 ,  G01N33/57426 ,  G01N2800/54

Abstract: Described herein are methods for determining the prognosis of a patient diagnosed with Acute Lymphoblastic Leukemia (ALL), and particularly determining the risk of disease relapse following standard treatment. Also described are systems of treatment that are directed by a health care provider, and which include the described prognostic methods and the treatments recommended for patients determined to have a specific relapse risk.

公开(公告)号：US20170202916A1

公开(公告)日：2017-07-20

申请号：US15129007

申请日：2015-03-30

Applicant: Ramot at Tel-Aviv University Ltd. ,  Mor Research Applications Ltd.

Inventor： Ruth SHALGI ,  Dana CHUDERLAND ,  Hadas BAR-JOSEPH ,  Keren GOLDBERG ,  Irit BEN-AHARON ,  Salomon M. STEMMER

IPC: A61K38/18 ,  C12N5/075 ,  G01N33/74 ,  A61K31/704 ,  A61K31/138

CPC classification number: A61K38/18 ,  A61K31/138 ,  A61K31/704 ,  C12N5/0609 ,  C12N2501/10 ,  G01N33/74 ,  G01N2333/475 ,  G01N2800/34 ,  G01N2800/36 ,  G01N2800/52 ,  G01N2800/709 ,  A61K2300/00

Abstract: A method of treating or preventing gonadal or uterine toxicity induced by an agent in a subject is provided. Accordingly there is provided a method comprising administering to a subject a therapeutically effective amount of pigment epithelium-derived factor (PEDF), thereby treating or preventing the gonadal toxicity induced by the agent. Also provided is, a method comprising determining gonadal function in a subject; and administering to the subject a therapeutically effective amount of PEDF, thereby treating or preventing the gonadal toxicity induced by the agent. Also provided is a PEDF for use in the treatment or prevention of gonadal toxicity induced by an agent in a subject. Also provided are cell culture, a medium, a kit and method for improving oocyte quality ex-vivo.

公开(公告)号：US20160310068A1

公开(公告)日：2016-10-27

申请号：US15102588

申请日：2014-12-09

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD. ,  MOR RESEARCH APPLICATIONS LTD.

Inventor： Lior HAVIV ,  Noam SOBEL ,  Amiram CATZ ,  Itzhak GLASS ,  Anton PLOTKIN ,  Aharon WEISSBROD ,  Sagit SHUSHAN

IPC: A61B5/00 ,  A61B5/11 ,  A61B5/08 ,  A61B5/087 ,  A61N1/36 ,  A61B5/0492

CPC classification number: A61B5/4836 ,  A61B5/0488 ,  A61B5/0492 ,  A61B5/0806 ,  A61B5/0816 ,  A61B5/0823 ,  A61B5/087 ,  A61B5/1103 ,  A61B5/7282 ,  A61B5/7475 ,  A61N1/36003 ,  A61N1/3601 ,  A61N1/36014 ,  A61N1/36017 ,  G06F3/012

Abstract: A system for assisted coughing includes a first sensor for measuring a parameter which can indicate a closed glottis and producing a first signal, a processor for receiving the first signal, determining a state indicating the closed glottis and generating an instruction for a Functional Electric Stimulation (FES) controller based, at least in part, on the determining, and a FES controller for generating an electric stimulation signal.

Abstract translation: 用于辅助咳嗽的系统包括用于测量可指示闭合声门并产生第一信号的参数的第一传感器，用于接收第一信号的处理器，确定指示闭合声门的状态并产生功能性电刺激指令（ FES）控制器，至少部分地基于确定，以及用于产生电刺激信号的FES控制器。

公开(公告)号：US20160089423A1

公开(公告)日：2016-03-31

申请号：US14891415

申请日：2014-05-12

Applicant: MOR RESEARCH APPLICATIONS LTD.

Inventor： Dan Abrahamov

IPC: A61K38/57 ,  A61K45/06 ,  A61K9/00

CPC classification number: A61K38/57 ,  A61K9/0019 ,  A61K45/06

Abstract: Disclosed herein are compositions and methods for treating damage inflicted by use of a cardio-pulmonary bypass (CPB) machine, particularly excessive bleeding and multi organ failure, by administering a pharmaceutical composition comprising alpha-1 antitrypsin (AAT).

Abstract translation: 本文公开了通过施用包含α-1抗胰蛋白酶（AAT）的药物组合物来治疗通过使用心肺旁路（CPB）机器造成的损伤，特别是过度出血和多器官功能衰竭的组合物和方法。

公开(公告)号：US20160029927A1

公开(公告)日：2016-02-04

申请号：US14874498

申请日：2015-10-05

Applicant: Mor Research Applications Ltd. ,  Ramot at Tel-Aviv University Ltd.

Inventor： Yehuda FINKELSTEIN ,  Lior WOLF

IPC: A61B5/107 ,  A61B5/08 ,  A61B5/00 ,  G06T7/00 ,  G06K9/46

CPC classification number: A61B5/1075 ,  A61B5/08 ,  A61B5/4818 ,  G06K9/46 ,  G06T7/0014 ,  G06T7/33 ,  G06T2200/04 ,  G06T2207/10116 ,  G06T2207/30008 ,  G06T2207/30036 ,  G06T2207/30196

Abstract: In a method of analysis, a target image is registered to define a plurality of keypoints arranged in sets corresponding to polygons or linear segments in the target image. A database of registered and annotated images is accessed and a polygon-wise comparison between the target image and each database image is employed. The comparison is used for projecting annotated locations from the database images into the target image.

Abstract translation: 在分析方法中，记录目标图像以定义与目标图像中的多边形或线性段对应的集合排列的多个关键点。 访问注册和注释的图像的数据库，并且采用目标图像和每个数据库图像之间的多边形比较。 比较用于将数据库图像中的注释位置投影到目标图像中。

公开(公告)号：US20140170644A1

公开(公告)日：2014-06-19

申请号：US14236686

申请日：2012-08-06

Applicant: Mor Research Applications Ltd.

Inventor： Amir Hadayer ,  Noa Hannah Hadayer ,  Arie Leonid Marcovich

IPC: G01N1/08

CPC classification number: G01N1/08 ,  C12M33/04 ,  G01N1/14 ,  G01N35/1079 ,  G01N2001/1427

Abstract: A sterile injector comprises a body having a cavity, a hollow needle positionable at a distal end of the injector, a probe holder receivable within the needle, a probe connected to a distal end of the holder, and a driving element axially displaceable within the cavity, for causing relative motion between the probe and the needle upon displacement of the driving element. A sample is injected into a sealed container by displacing the driving element to a first position causing the probe to extend from the needle, applying the extended probe with a sample, displacing the driving element to a second position causing the sample laden probe to be retracted within the needle, piercing a seal of a sealed container with the needle, and displacing the driving element to a third position distally spaced from the first position, after which the probe is injected into the container interior.

Abstract translation: 无菌注射器包括具有空腔的主体，可定位在注射器的远端的中空针，可接收在针内的探针保持器，连接到保持器的远端的探针和可在腔内轴向移位的驱动元件 用于在驱动元件移位时引起探针和针之间的相对运动。 将样品通过将驱动元件移位到第一位置而被注入到密封容器中，使第一位置使得探针从针上延伸，将样品施加到扩展的探针上，将驱动元件移位到第二位置，使得载有样本的探针被缩回 在针内，用针刺穿密封容器的密封，并将驱动元件移位到远离第一位置的第三位置，之后将探针注入容器内部。