公开(公告)号：US5458596A

公开(公告)日：1995-10-17

申请号：US238862

申请日：1994-05-06

Applicant: Ronald G. Lax ,  Gary S. Fanton ,  Stuart D. Edwards

Inventor： Ronald G. Lax ,  Gary S. Fanton ,  Stuart D. Edwards

IPC: A61B17/56 ,  A61B18/00 ,  A61B18/12 ,  A61B18/14 ,  A61N1/06 ,  A61N1/40

CPC classification number: A61B18/148 ,  A61N1/40 ,  A61B2018/00023 ,  A61B2018/00083 ,  A61B2018/00452 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/143 ,  A61B2018/1472 ,  A61B2018/1497 ,  A61B2018/1861

Abstract: An apparatus and method are provided for control contraction of tissue that includes collagen fibers. The apparatus includes a handpiece, and an electrode with an electrode proximal end associated with the handpiece. A distal end of the electrode has a geometry that delivers a controlled amount of energy to the tissue for a desired contraction of the collagen fibers. This is achieved while dissociation and breakdown of the collagen fibers is minimized. The handpiece, with electrode, is adapted to be introduced through an operating cannula in percutaneous applications. Additionally, an operating cannula may be included in the apparatus and be attached to the handpiece. The apparatus and method provides for a desired level of contraction of collagen soft tissue without dissociation or breakdown of collagen fibers.

公开(公告)号：US5398683A

公开(公告)日：1995-03-21

申请号：US92762

申请日：1993-07-16

Applicant: Stuart D. Edwards ,  Michael R. Franz ,  Russel B. Thompson ,  Roger A. Stern

Inventor： Stuart D. Edwards ,  Michael R. Franz ,  Russel B. Thompson ,  Roger A. Stern

IPC: A61B5/0492 ,  A61B5/0402 ,  A61B5/042 ,  A61B5/0478 ,  A61B17/00 ,  A61B18/12 ,  A61B18/14 ,  A61N1/05 ,  A61B5/04

CPC classification number: A61B18/1206 ,  A61B18/12 ,  A61B18/1492 ,  A61B5/0422 ,  A61N1/056 ,  A61B2017/00292 ,  A61B2017/003 ,  A61B2017/00473 ,  A61B2018/00107 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/0066 ,  A61B2018/00839 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1495 ,  A61B2018/1497 ,  A61B2018/162

Abstract: A combination catheter for both detecting monophasic action potentials and ablating surface tissue in an in vivo heart of a patient is provided. The apparatus includes a catheter probe having a terminal tip portion and an electrode carried on the tip such that a portion of the tip electrode is exposed to ambient. A reference electrode is spaced along the tip from the first electrode for supplying a reference potential signal. An ablating electrode is located adjacent to but electrically insulated from both the tip and reference electrodes for providing electromagnetic energy to the tip. The electrodes are electrically connected to the proximal end of the catheter through individual conductors or wires that run through an insulated cable. An electronic filter is provided to permit the recording of MAPs during ablation without radiofrequency interference. The catheter may also include standard mapping and/or pacing electrodes. The catheter may further include a steering mechanism for positioning the catheter at various treatment sites in the heart, and a structure for holding the tip electrode in substantially perpendicular contact with heart tissue with a positive pressure, and for spacing the reference electrode from the heart tissue.

Abstract translation: 提供了用于检测患者的体内心脏中的单相动作电位和消融表面组织的组合导管。 该装置包括导管探针，其具有端子末端部分和在尖端上承载的电极，使得尖端电极的一部分暴露于环境中。 参考电极沿着尖端与第一电极间隔开，以提供参考电位信号。 烧蚀电极位于与尖端和参考电极相邻但电绝缘的位置，用于向尖端提供电磁能。 电极通过穿过绝缘电缆的各个导体或电线电连接到导管的近端。 提供电子滤波器以允许在消融期间MAP的记录而没有射频干扰。 导管还可以包括标准贴图和/或起搏电极。 导管还可以包括用于将导管定位在心脏中的各种治疗部位的转向机构，以及用于将尖端电极与正常压力基本上垂直接触心脏组织并将参考电极与心脏组织间隔开的结构 。

公开(公告)号：US5370678A

公开(公告)日：1994-12-06

申请号：US163371

申请日：1993-12-07

Applicant: Stuart D. Edwards ,  Jerome Jackson ,  Roger A. Stern ,  Thomas M. Morse ,  Patrick M. Owens

Inventor： Stuart D. Edwards ,  Jerome Jackson ,  Roger A. Stern ,  Thomas M. Morse ,  Patrick M. Owens

IPC: A61B17/22 ,  A61B18/18 ,  A61N1/05 ,  A61N1/06 ,  A61N5/02

CPC classification number: A61N1/05 ,  A61B17/22 ,  A61B18/18 ,  A61B18/1815 ,  A61N1/06 ,  A61B2018/1861

Abstract: An antenna assembly has an energy propagating region that is encapsulated in a material having a high dielectric constant for minimizing the loss of energy while having a high thermal conductivity for dissipating conductive heat patterns about the energy propagating region.

Abstract translation: 天线组件具有能量传播区域，该能量传播区域被封装在具有高介电常数的材料中，以最小化能量损失，同时具有高热导率以消散围绕能量传播区域的导电热图案。

公开(公告)号：US5314466A

公开(公告)日：1994-05-24

申请号：US868113

申请日：1992-04-13

Applicant: Roger A. Stern ,  Stuart D. Edwards ,  Jerome Jackson ,  Arye Rosen

Inventor： Roger A. Stern ,  Stuart D. Edwards ,  Jerome Jackson ,  Arye Rosen

IPC: A61B17/22 ,  A61B17/28 ,  A61B18/14 ,  A61B18/18 ,  A61N5/02

CPC classification number: A61B18/1815 ,  A61B17/22 ,  A61B18/1492 ,  A61B18/18 ,  A61B2017/2902 ,  A61B2017/2912 ,  A61B2017/2919 ,  A61B2017/2927 ,  A61B2017/2939 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/183

Abstract: An improved assembly for steering and orienting a functional element at the distal end of a catheter tube holds the functional element with its major axis aligned with the axis of the catheter tube for convenient steering to a tissue site. The mechanism can also pivot the functional element in response to an external force to orient the major axis of the functional element generally parallel to the plane of the tissue site, without bending the catheter tube.

Abstract translation: 用于在导管管的远端处转向和定向功能元件的改进的组件保持功能元件，其主轴与导管管的轴线对准，以便于转向组织部位。 机构还可以响应于外力使功能元件枢转，以使功能元件的长轴大致平行于组织部位的平面定向，而不弯曲导管。

公开(公告)号：US5293869A

公开(公告)日：1994-03-15

申请号：US951160

申请日：1992-09-25

Applicant: Stuart D. Edwards ,  Jerome Jackson

Inventor： Stuart D. Edwards ,  Jerome Jackson

IPC: A61B5/042 ,  A61B5/0402

CPC classification number: A61B5/6856 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/6852 ,  A61B5/6853 ,  A61B5/6858 ,  A61B5/6859 ,  A61B2562/0209 ,  A61B2562/043

Abstract: A cardiac probe employs a dynamic mounting element that supports one or more electrodes at its distal end in relatively constant surface contact against the expanding and contact endocardial surface.

Abstract translation: 心脏探针使用动态安装元件，其在其远端处支撑一个或多个电极，以相对于膨胀和接触的心内膜表面相对恒定的表面接触。

公开(公告)号：US5257451A

公开(公告)日：1993-11-02

申请号：US790206

申请日：1991-11-08

Applicant: Stuart D. Edwards ,  Russell B. Thompson

Inventor： Stuart D. Edwards ,  Russell B. Thompson

IPC: A61M25/01 ,  A61N1/05 ,  B29C61/02 ,  H01R13/56 ,  H01R43/00

CPC classification number: A61M25/0138 ,  A61M25/0144 ,  A61M25/0147 ,  A61N1/0565 ,  B29C61/025 ,  H01R13/56 ,  A61M2025/0161 ,  Y10S174/08 ,  Y10T29/49117 ,  Y10T29/49194

Abstract: A reinforcing sleeve encloses a bendable electrode tip assembly for a catheter. The reinforcing sleeve is flexible enough to accommodate the bending movement desired for the electrode tip assembly. Still, the reinforcing sleeve provides added strength and resistance against wear and tear during repeated bending operations. The reinforcing sleeve also holds associated steering wires and electrical conducting wires in close intimate contact against the interior support wire of the electrode tip assembly. The intimate contact prevents kinking and chafing of the steering wires and electrical conducting wires during bending operations.

Abstract translation: 加强套管包围用于导管的可弯曲电极末端组件。 加强套筒足够柔韧以适应电极头组件所需的弯曲运动。 仍然，加强套筒在反复弯曲操作期间提供附加的强度和抵抗磨损和抗撕裂的能力。 加强套筒还保持相关联的操纵线和电导线与电极头组件的内部支撑线紧密接触。 紧密接触可防止弯曲操作期间转向导线和导电线的扭结和擦伤。

公开(公告)号：US08906010B2

公开(公告)日：2014-12-09

申请号：US12001091

申请日：2007-12-10

Applicant: Stuart D Edwards ,  John W. Gaiser ,  David S Utley ,  Scott H. West ,  Jay Qin ,  Peter H Muller

Inventor： Stuart D Edwards ,  John W. Gaiser ,  David S Utley ,  Scott H. West ,  Jay Qin ,  Peter H Muller

IPC: A61B18/14 ,  A61B18/12 ,  A61B19/00 ,  A61B18/00 ,  A61B18/04

CPC classification number: A61B18/12 ,  A61B18/1206 ,  A61B18/1477 ,  A61B18/1485 ,  A61B18/1492 ,  A61B2018/00011 ,  A61B2018/00029 ,  A61B2018/00077 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00553 ,  A61B2018/00654 ,  A61B2018/0066 ,  A61B2018/00702 ,  A61B2018/00755 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/046 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2090/3782 ,  A61B2218/002 ,  A61B2218/007

Abstract: Systems and methods deploy an electrode structure in contact with the tissue region. The electrode structure carries a sensor at a known location on the electrode structure to monitor an operating condition. The systems and methods provide an interface, which generate an idealized image of the electrode structure and an indicator image to represent the monitored operating condition in a spatial position on the idealized image corresponding to the location of the sensor on the electrode structure. The interface displays a view image comprising the idealized image and indicator image. The systems and methods cause the electrode structure to apply energy to heat the tissue region while the view image is displayed on the display screen.

Abstract translation: 系统和方法部署与组织区域接触的电极结构。 电极结构在电极结构上的已知位置处携带传感器以监测操作状态。 系统和方法提供了一种接口，其产生电极结构的理想化图像和指示图像，以在对应于电极结构上的传感器的位置的理想化图像上的空间位置中表示监视的操作条件。 界面显示包含理想图像和指示图像的视图。 当视觉图像显示在显示屏上时，系统和方法使电极结构施加能量来加热组织区域。

公开(公告)号：US20140005660A1

公开(公告)日：2014-01-02

申请号：US14015993

申请日：2013-08-30

Applicant: Stuart D. Edwards ,  John W. Gaiser ,  David S. Utley ,  Jay J. Qin

Inventor： Stuart D. Edwards ,  John W. Gaiser ,  David S. Utley ,  Jay J. Qin

IPC: A61B18/18

CPC classification number: A61B18/14 ,  A61B17/32 ,  A61B18/1206 ,  A61B18/1477 ,  A61B18/148 ,  A61B18/1485 ,  A61B18/1492 ,  A61B18/18 ,  A61B18/1815 ,  A61B2017/00084 ,  A61B2017/00106 ,  A61B2017/003 ,  A61B2017/22061 ,  A61B2017/4216 ,  A61B2018/00011 ,  A61B2018/00023 ,  A61B2018/00029 ,  A61B2018/00065 ,  A61B2018/00077 ,  A61B2018/00083 ,  A61B2018/00113 ,  A61B2018/00148 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00488 ,  A61B2018/00494 ,  A61B2018/00553 ,  A61B2018/00577 ,  A61B2018/00648 ,  A61B2018/00654 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00708 ,  A61B2018/00726 ,  A61B2018/00744 ,  A61B2018/00755 ,  A61B2018/00761 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00827 ,  A61B2018/00875 ,  A61B2018/00886 ,  A61B2018/00892 ,  A61B2018/00898 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/00982 ,  A61B2018/0262 ,  A61B2018/046 ,  A61B2018/124 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1273 ,  A61B2018/1405 ,  A61B2018/1467 ,  A61B2018/1472 ,  A61B2018/183 ,  A61B2090/3614 ,  A61B2090/3782 ,  A61B2217/007 ,  A61B2218/002 ,  A61M3/0279 ,  A61M16/0438 ,  A61M16/0481 ,  A61M25/1002 ,  A61M2025/1052 ,  A61M2025/1086 ,  A61N1/056 ,  A61N1/06 ,  A61N1/08 ,  A61N1/40

Abstract: An apparatus treats tissue at or near a sphincter. The apparatus has an elongated member having at least one lumen including an inflation lumen, and a basket assembly including a first and a second arm. An inflatable member is coupled to the inflation lumen and has a deployed and a non-deployed state. In the deployed state, the inflatable member expands the basket assembly into contact with tissue. At least one of the first and second arms of the basket assembly has a fluid lumen having an aperture for conveying a fluid from the basket assembly. A source of fluid is coupled to the fluid lumen for conveyance of fluid through the aperture. The fluid can be, e.g., an electrolytic solution, and/or an anti-infection agent, and/or an echogenic media, and/or a steroid, and/or an anesthetic, and/or a medicament, and/or a tissue cooling agent. The source can be a drug delivery device.

Abstract translation: 装置处理括约肌处或附近的组织。 该装置具有细长构件，其具有包括充气腔的至少一个腔，以及包括第一臂和第二臂的篮组件。 可膨胀构件联接到膨胀腔并具有展开和非展开状态。 在展开状态下，可膨胀构件将篮组件膨胀成与组织接触。 篮组件的第一和第二臂中的至少一个具有流体腔，其具有用于从篮组件输送流体的孔。 流体源耦合到流体腔，用于输送流体通过该孔。 流体可以是例如电解溶液和/或抗感染剂和/或回声介质，和/或类固醇，和/或麻醉剂，和/或药物，和/或组织 冷却剂。 来源可以是药物递送装置。

公开(公告)号：US20130253509A1

公开(公告)日：2013-09-26

申请号：US13902830

申请日：2013-05-26

Applicant: Stuart D. Edwards ,  David S. Utley ,  Ronald G. Lax ,  Theodore R. Kucklick ,  Peter H. Muller

Inventor： Stuart D. Edwards ,  David S. Utley ,  Ronald G. Lax ,  Theodore R. Kucklick ,  Peter H. Muller

IPC: A61B18/14

CPC classification number: A61B18/14 ,  A61B17/32 ,  A61B18/1477 ,  A61B18/1492 ,  A61B18/1815 ,  A61B2018/00011 ,  A61B2018/00029 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00494 ,  A61B2018/00553 ,  A61B2018/00577 ,  A61B2018/00702 ,  A61B2018/00726 ,  A61B2018/00744 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00916 ,  A61B2018/124 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1472 ,  A61B2018/183 ,  A61B2090/3614 ,  A61B2090/3782

Abstract: A sphincter treatment apparatus includes an energy delivery device introduction member including a proximal end with a first radius of curvature and a distal end with a second radius of curvature. The introduction member is configured to be introduced into the sphincter in a non-deployed state and to be expanded to a deployed state to at least partially expand the sphincter or an adjoining structure. An energy delivery device is coupled to the introduction member. A retainer member is coupled to the energy delivery device introduction member and configured to controllably position the introduction member in an orifice of the sphincter.

Abstract translation: 括约肌治疗装置包括能量输送装置导入构件，其包括具有第一曲率半径的近端和具有第二曲率半径的远端。 引入构件被配置为以非展开状态引入括约肌并且被扩展到展开状态以至少部分地扩展括约肌或相邻结构。 能量输送装置联接到引入构件。 保持器构件联接到能量输送装置引入构件并构造成将引导构件可控地定位在括约肌的孔中。

公开(公告)号：US08518032B2

公开(公告)日：2013-08-27

申请号：US12291626

申请日：2008-11-12

Applicant: Stuart D Edwards ,  David S Utley ,  Ronald G Lax ,  John Gaiser

Inventor： Stuart D Edwards ,  David S Utley ,  Ronald G Lax ,  John Gaiser

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B18/1206 ,  A61B18/1477 ,  A61B18/18 ,  A61B2018/00011 ,  A61B2018/00029 ,  A61B2018/00047 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00494 ,  A61B2018/00553 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00684 ,  A61B2018/00702 ,  A61B2018/00708 ,  A61B2018/00726 ,  A61B2018/00744 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/124 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1425 ,  A61B2218/002

Abstract: A method for treating a sphincter provides a polymer material having a liquid state. The method also provides a catheter having a distal end, a tissue piercing device carried by the distal end, and an energy delivery device coupled to the tissue piercing device. The tissue piercing device has a lumen. The method introduces the catheter into an esophagus and pierces an exterior sphincter tissue surface within with the tissue piercing device. The method advances the tissue piercing device into an interior sphincter tissue site and conveys the polymer material while in a liquid state through the lumen into the interior sphincter tissue site. The method delivers energy to the tissue piercing device to transform the polymer material into a less liquid state within the interior sphincter tissue site, to thereby remodel the sphincter.