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254 条记录 (耗时 0.04 秒)

    Pyridazinone and triazinone compounds and use thereof as pharmaceutical preparations
    156.
    发明申请
    Pyridazinone and triazinone compounds and use thereof as pharmaceutical preparations 审中-公开
    哒嗪酮和三嗪酮化合物及其作为药物制剂的用途

    公开(公告)号：US20060189622A1

    公开(公告)日：2006-08-24

    申请号：US11408078

    申请日：2006-04-21

    申请人： Satoshi Nagato ,  Koki Kawano ,  Koichi Ito ,  Yoshihiko Norimine ,  Kohshi Ueno ,  Takahisa Hanada ,  Hiroyuki Amino ,  Makoto Ogo ,  Shinji Hatakeyama ,  Masataka Ueno ,  Anthony Groom ,  Leanne Rivers ,  Terence Smith

    发明人： Satoshi Nagato ,  Koki Kawano ,  Koichi Ito ,  Yoshihiko Norimine ,  Kohshi Ueno ,  Takahisa Hanada ,  Hiroyuki Amino ,  Makoto Ogo ,  Shinji Hatakeyama ,  Masataka Ueno ,  Anthony Groom ,  Leanne Rivers ,  Terence Smith

    IPC分类号： A61K31/506 ,  A61K31/501 ,  A61K31/50 ,  C07D409/02 ,  C07D403/02 ,  C07D405/02

    CPC分类号： C07D237/24 ,  C07D237/14 ,  C07D401/04 ,  C07D491/04

    摘要： The present invention provides a novel compound exhibiting an excellent inhibitory action on AMPA receptor and/or kainate receptor. That is, it provides a compound represented by the following formula, a salt thereof or a hydrate of them. In the formula, A1, A2 and A3 are independent of each other and each represents a C3-8 cycloalkyl group, a C3-8 cycloalkenyl group, a 5- to 14-membered non-aromatic heterocyclic group, a C6-14 aromatic hydrocarbon cyclic group or a 5- to 14-membered aromatic heterocyclic group, each of which may be substituted; Q represents O, S or NH; Z represents C or N; X1, X2 and X3 are independent of each other and each represents a single bond, an optionally substituted C1-6 alkylene group, an optionally substituted C2-6 alkenylene group, an optionally substituted C2-6 alkynylene group, —NH—, —O—, —NHCO—, —CONH—, —SO0-2—, etc.; R1 and R2 are independent of each other and each represents a hydrogen atom or an optionally substituted C1-6 alkyl group, or R1 and R2 may be bound together such that CR2-ZR1 forms C═C; and R3 represents a hydrogen atom or an optionally substituted C1-6 alkyl group etc., or may be bound to any atom in A1 or A3 to form, together with the atom, an optionally substituted C5-8 hydrocarbon ring or an optionally substituted 5- to 8-membered heterocyclic ring.

    摘要翻译： 本发明提供了对AMPA受体和/或红藻氨酸受体具有优异抑制作用的新化合物。 也就是说，它提供由下式表示的化合物，其盐或它们的水合物。 在该式中，A 1，A 2和A 3彼此独立，并且各自表示C 3-8， 环烷基，C 3-8环烯基，5至14元非芳族杂环基，C 6-14芳族烃环基 或5〜14元芳族杂环基，其各自可以被取代; Q表示O，S或NH; Z表示C或N; X 1，X 2和X 3 3彼此独立，各自表示单键，任选取代的C 1〜 6个亚烷基，任选取代的C 2-6亚烯基，任选取代的C 2-6亚炔基，-NH-，-O-， -NHCO - ， - CONH - ， - SO 2 - 等; R 1和R 2彼此独立，各自表示氢原子或任选取代的C 1-6烷基，或R 可以将“1”和“R”2结合在一起，使得CR 2 -ZR 1'形成CC; 和R 3表示氢原子或任选取代的C 1-6烷基等，或者可以与A 1〜O 2中的任何原子结合 >或A <3>，以与原子一起形成任选取代的C 5 -C 8烃环或任选取代的5至8元杂环。

    Portable wireless communication terminal and control method
    157.
    发明授权
    Portable wireless communication terminal and control method 有权

    公开(公告)号：US06996416B2

    公开(公告)日：2006-02-07

    申请号：US09948395

    申请日：2001-09-07

    申请人： Koichi Ito

    发明人： Koichi Ito

    IPC分类号： H04M1/00

    CPC分类号： H04M1/72522 ,  H04M1/72558 ,  Y02D70/1222

    摘要： A portable wireless communication terminal having a wireless communication function and a music recording and/or replaying function determines whether the wireless communication function is to be disable or not when an user selects the music recording/replaying function. The wireless communication function is enabled or disabled based on a result of the determination. More particularly, noise interference to the music recording/replaying function is alleviated by decreasing a transmitting power of the portable wireless communication terminal by a predetermined amount during music recording/replaying operation.

    Vehicle air conditioner with mode switching pattern
    160.
    发明授权
    Vehicle air conditioner with mode switching pattern 失效
    车载空调带模式切换模式

    公开(公告)号：US06761214B2

    公开(公告)日：2004-07-13

    申请号：US10191640

    申请日：2002-07-09

    申请人： Nobukazu Kuribayashi ,  Tatsumi Kumada ,  Shigeki Harada ,  Koichi Ito ,  Junji Yokoi

    发明人： Nobukazu Kuribayashi ,  Tatsumi Kumada ,  Shigeki Harada ,  Koichi Ito ,  Junji Yokoi

    IPC分类号： B60H100

    CPC分类号： B60H1/00842

    摘要： A vehicle air conditioner has an actuator for driving an air mixing door and various mode switching doors. An automatic range and a manual range are set in different operating angle ranges of the actuator. In the automatic range, an air outlet mode is automatically switched in accordance with an opening degree of the air mixing door. On the other hand, in the manual range, a multi-mode or a defroster mode is manually set, regardless of the opening degree of the air mixing door. In the manual range, air is simultaneously blown from all openings such as a face opening, a foot opening and a defroster opening in the multi-mode, and air is blown from the defroster opening in the defroster mode.

    摘要翻译： 车辆空调具有用于驱动空气混合门和各种模式切换门的致动器。 自动量程和手动量程设置在执行器的不同操作角度范围内。 在自动量程中，根据空气混合门的开度自动切换出气口模式。 另一方面，在手动范围中，无论空气混合门的开度如何，手动设定多模式或除霜模式。 在手动范围内，空气同时从多模式的面孔，脚踏开口和除霜器开口等所有开口吹出，在除霜模式下，从除霜器开口吹出空气。