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公开(公告)号:US20210047636A1
公开(公告)日:2021-02-18
申请号:US16915834
申请日:2020-06-29
Inventor: Federico KATZEN , Jonathan CHESNUT , Frank NOTKA , Matthias ARNOLD , Kevin HOFF , Stephen WHITESIDE
IPC: C12N15/10 , C07K14/195 , C12N15/66 , C12N9/90 , C12N9/96
Abstract: The invention generally relates to compositions and methods for designing and producing functional DNA binding effector molecules and associated customized services, tool kits and functional assays. In some aspects, the invention provides methods and tools for efficient assembly of customized TAL effector molecules. Furthermore, the invention relates to uses of TAL effector molecules and functional evaluation of such TAL by, for example, customized assays.
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公开(公告)号:US20210046200A1
公开(公告)日:2021-02-18
申请号:US17086723
申请日:2020-11-02
Applicant: Life Technologies Corporation
Inventor: Michael E. Goodwin , Nephi D. Jones , Bradley H. Buchanan
Abstract: A method for collecting a sterilized fluid includes passing a fluid through an inlet stem and into a chamber of a storage container so that the fluid collects within the chamber of the storage container; and applying a beam of radiation to the inlet stem so that the beam of radiation passes through the inlet stem and through at least a portion of the fluid passing through the inlet stem, the beam of radiation at least partially sterilizing the fluid passing through the inlet stem and into the chamber of the storage container.
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公开(公告)号:US10921218B2
公开(公告)日:2021-02-16
申请号:US16222933
申请日:2018-12-17
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Joel Colburn , Mousumi Rath , Sarah Ghanbari
Abstract: A carrier for holding a biological sample includes a substrate. The substrate is configured to engage a first sample chamber comprising a first opening characterized by a first opening diameter or a second sample chamber comprising a second opening characterized by a second opening diameter that is greater than the first opening diameter. The substrate includes an upper portion, a lower portion, and an intermediate portion disposed between the upper portion and the lower portion. The lower portion is disposed below the upper portion and comprises a bottom surface configured to receive a biological sample. The intermediate portion is characterized by a first substrate diameter and the lower portion is characterized by a second substrate diameter that is less than the first substrate diameter.
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公开(公告)号:US20210024882A1
公开(公告)日:2021-01-28
申请号:US16921626
申请日:2020-07-06
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Sarya MANSOUR , Joanna KERN , Anson PIERCE , Pei-Yi LIN
IPC: C12N5/00 , C12N13/00 , C12N5/0783 , C12N15/87
Abstract: Provided herein are improvements in cell culture methods and compositions related thereto. In partial particular, provided herein are compositions and methods, and kits increasing the cellular division times and viability. Also provided herein are compositions and method for performing electroporation where high levels of electroporation efficiency are achieved and where deleterious effect of electroporation on cells are decreased.
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公开(公告)号:US10898870B2
公开(公告)日:2021-01-26
申请号:US15799580
申请日:2017-10-31
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Jeffery C. Hurd , Nephi D. Jones , Jacob D. Lee
Abstract: A liquid mixing system includes a support housing at least partially bounding a compartment. A mount is secured to the support housing. A drive motor assembly is configured to engage a drive shaft for moving the drive shaft within the compartment of the support housing. A four bar linkage system extends between the mount and the drive motor assembly, the four bar linkage system being movable between a first position wherein the drive motor assembly is disposed at a first elevation and a second position wherein the drive motor assembly is disposed at a second elevation that is different from the first elevation.
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公开(公告)号:US20210018423A9
公开(公告)日:2021-01-21
申请号:US16282793
申请日:2019-02-22
Applicant: Life Technologies Corporation
Inventor: Michael D. Ward , Gregory Kaduchak
IPC: G01N15/14 , G01N29/22 , G01N27/447 , G01N21/64 , G01N33/569 , A61M1/36 , G01N15/12
Abstract: The present invention comprises methods and systems that use acoustic radiation pressure.
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公开(公告)号:US20210009942A1
公开(公告)日:2021-01-14
申请号:US17037454
申请日:2020-09-29
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Mwita PHELPS , Paul GULDE , Richard FIKE , Mary REYNOLDS , Richard HASSETT , Andrew CAMPBELL
Abstract: The present invention is directed generally to dry cell culture media or feeds in pellet formats which can be reconstituted into liquid media for culturing cells in vitro. Each pellet composition may comprise the same or a different composition; for example, different vitamins, amino acids, buffers, trace salts, pH, iron chelators, etc. The invention also relates to methods of making dry cell culture media by altering ratios of different pellet compositions, or, methods of making modular dry cell culture media, or customizing media formulations for growing a cell type using pellets. The media pellets may be easier to handle either before reconstitution, during shipping and handling; and/or during reconstitution. Media pellets may be used in any container like bags including sterile, single use bags for preparing media formulations. The invention also relates to kits and culture systems using media pellets.
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公开(公告)号:USD907797S1
公开(公告)日:2021-01-12
申请号:US29695503
申请日:2019-06-19
Applicant: LIFE TECHNOLOGIES CORPORATION
Designer: Earl Zergiebel
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公开(公告)号:USD901717S1
公开(公告)日:2020-11-10
申请号:US29661397
申请日:2018-08-27
Applicant: LIFE TECHNOLOGIES CORPORATION
Designer: Axel Unger , Elgin Meike Toepfer Taylor , Nicole Busch , Tom Hynek , Fredrik Aidehag , Todd Pelman , Martin Naley
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公开(公告)号:USD901716S1
公开(公告)日:2020-11-10
申请号:US29661395
申请日:2018-08-27
Applicant: LIFE TECHNOLOGIES CORPORATION
Designer: Axel Unger , Elgin Meike Toepfer Taylor , Nicole Busch , Tom Hynek , Fredrik Aidehag , Todd Pelman , Martin Naley
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