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公开(公告)号：US20210223147A1
公开(公告)日：2021-07-22
申请号：US16096096
申请日：2018-08-09
Applicant: Kimoto Electric Co., Ltd. , Osaka University
Inventor： Takashi KIMOTO , Michisato TOYODA , Hiroshi NAKAYAMA
Abstract: A mixed solution in which a compound which forms a nonvolatile membrane at a gas-liquid interface through self-aggregation is dispersed in a volatile liquid, is ejected and atomized in a gas or in a vacuum to produce a droplet particle, and a nonvolatile membrane is then formed at the gas-liquid interface by aligning the compound on a surface of the droplet particle having a reduced diameter due to evaporation of the volatile liquid in the gas or in the vacuum to stabilize the droplet particle. The method produces a novel droplet particle which stably exists in a gas or in a vacuum without collapsing or without evaporation of the volatile liquid inside the droplet particle.
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公开(公告)号：US20210220942A1
公开(公告)日：2021-07-22
申请号：US15734338
申请日：2019-05-28
Applicant: OSAKA UNIVERSITY
Inventor： Hidetoshi Fujii , Yoshiaki Morisada , Yasuhiro Aoki , Akihiko Ikuta
IPC: B23K20/12
Abstract: Provided are a long-life and inexpensive friction stir welding tool that is not dependent on the mode of friction stir welding or the type of material to be welded, and a friction stir welding method using the friction stir welding tool. The friction stir welding tool comprises a body portion having a shoulder portion, and a probe portion disposed on a bottom surface of the body portion, and is characterized in that the probe portion is spherical-crown shaped. Preferably, the shoulder portion is flat or convex, and preferably the hardness of the shoulder portion is greater than the hardness of the probe portion.
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163.发明申请公开(公告)号：US20210214775A1
公开(公告)日：2021-07-15
申请号：US17252982
申请日：2019-06-28
Applicant: OSAKA UNIVERSITY , OTSUKA PHARMACEUTICAL CO., LTD.
Inventor： Kohji NISHIDA , Noriyasu HASHIDA , Tetsuya IIDA , Shota NAKAMURA , Daisuke MOTOOKA , Kazunobu ASAO , Satoru ANDO
Abstract: It aims to construct a technology in which the onset or progression of an aging state or a specific disease can be evaluated in an objective and highly reproducible manner, and in particular, to provide a method of detecting conjunctival diseases such as conjunctival MALT lymphoma, and to provide an aging biomarker that serves as an indicator of the aging state.
A method of detecting a conjunctival disease using an ocular surface tissue, the method comprising a step of comparing a microbial community structure of a microbiota included in an ocular surface tissue specimen sampled from a healthy person, with a microbial community structure of a microbiota included in an ocular surface tissue specimen sampled from a subject to detect an ocular surface tissue specimen which is sampled from the subject evaluated as having the conjunctival disease based on a change in the microbial community structure between the healthy person and the subject, and an aging biomarker for detecting an aging state, the aging biomarker comprising a bacterial species which belongs to at least one family selected from Corynebacteriaceae family and Propionibacteriales family in an ocular surface tissue.-
公开(公告)号：US11061088B2
公开(公告)日：2021-07-13
申请号：US16548121
申请日：2019-08-22
Applicant: Osaka University , JEOL Ltd.
Inventor： Toshimichi Fujiwara , Yoh Matsuki , Yuki Endo , Shinji Nakamura , Hiroki Takahashi
Abstract: A container has a sample installation unit and an NMR circuit therein, and is connected to a bearing gas supply path and a drive gas supply path for supplying gas to the inside of that container. This container is also connected to an exhaust path that exhausts the gas from the inside of the container. The exhaust path has a pressure control valve as an adjustment mechanism for adjusting the pressure in the container.
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公开(公告)号：US20210210244A1
公开(公告)日：2021-07-08
申请号：US16980617
申请日：2019-03-01
Applicant: OSAKA UNIVERSITY
Inventor： Atsushi SHINOHARA , Atsushi TOYOSHIMA , Zijian ZHANG , Akimitsu KANDA , Soichiro ICHIMURA
Abstract: There is provided a radionuclide manufacturing system, a computer-readable storage medium storing a radionuclide manufacturing program, a radionuclide manufacturing method, and a terminal device for more stably manufacturing a radionuclide.
A radionuclide manufacturing system includes: a heating unit configured to internally house a target holding a radionuclide; a gas supply unit; an adsorption unit configured to adsorb the radionuclide; a solvent supply unit; a storage unit configured to store a predetermined instruction; and a control unit configured to control the heating unit to heat the target at a temperature at which the radionuclide held in the target is allowed to volatilize, to control the gas supply unit to supply the carrier gas to the heating unit in order to transport the radionuclide volatilized in the heating unit to the adsorption unit, and to control the solvent supply unit in order to supply a solvent for eluting the radionuclide adsorbed to the adsorption unit to the adsorption unit based on the instruction.-
Patent Agency Ranking
公开(公告)号：US20210205446A1
公开(公告)日：2021-07-08
申请号：US17200552
申请日：2021-03-12
Applicant: OSAKA UNIVERSITY , FUNPEP CO., LTD.
Inventor： Hironori NAKAGAMI , Ryuichi MORISHITA , Akiko TENMA
IPC: A61K39/39 , A61K39/00 , A61P37/04 , A61K39/395
Abstract: The present invention provides a vaccine containing a complex of a peptide consisting of the amino acid sequence of SEQ ID NO: 1 and an epitope of a disease-causing biological protein such as DPP4, IL-17A, IgE, S100A9 or PCSK9, which vaccine uses a less antigenic carrier protein and is capable of inducing antibody production to serve as an effective vaccine.
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公开(公告)号：US20210205234A1
公开(公告)日：2021-07-08
申请号：US17163871
申请日：2021-02-01
Applicant: OSAKA UNIVERSITY , NATIONAL INSTITUTE FOR MATERIALS SCIENCE , NIPPON ZOKI PHARMACEUTICAL CO., LTD.
Inventor： Hiroyuki TANAKA , Kiyoshi OKADA , Hideki YOSHIKAWA , Koji SUZUKI , Mitsuhiro EBARA
IPC: A61K9/70 , A61K47/34 , A61K47/36 , A61K31/714 , A61K35/36 , A61K45/00 , A61K38/18 , A61P25/02 , A61K47/32
Abstract: A sustained release sheet that includes a drug for treating nerve injury, wherein the sheet is applied to a nerve injury site, can maintain a high concentration of the drug over a long period, and promotes nerve regeneration without stimulating the nerves, even when the sheet is implanted in the periphery of the nerve injury site. Also provided is a production method for the sheet. This sustained drug release sheet for treating nerve injury is a sheet including a non-woven fabric that is formed from nanofibers each containing a drug such as vitamin B12 and a biocompatible polymer such as a biodegradable aliphatic polyester, and is implanted in the periphery of the nerve injury site to promote nerve regeneration.
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公开(公告)号：US11054363B2
公开(公告)日：2021-07-06
申请号：US16936138
申请日：2020-07-22
Applicant: The University of Tokyo , Osaka University
Inventor： Sadao Ota , Ryoichi Horisaki , Kazuki Hashimoto
Abstract: Any one or both of an optical system with a structured lighting pattern and a structured detecting system having a plurality of regions with different optical characteristics are used. In addition, optical signals from an object to be observed through one or a small number of pixel detectors are detected while changing relative positions between the object to be observed and any one of the optical system and the detecting system, time series signal information of the optical signals are obtained, and an image associated with an object to be observed from the time series signal information is reconstructed.
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公开(公告)号：US20210202947A1
公开(公告)日：2021-07-01
申请号：US17192975
申请日：2021-03-05
Applicant: KANEKA CORPORATION , OSAKA UNIVERSITY
Inventor： Takashi Kikuchi , Kohei Ogawa , Kazuaki Kanai , Makio Naito , Takahiro Kozawa
Abstract: A method for producing a positive electrode active material is provided. The method can prevent a gas generation due to an oxidative degradation of a non-aqueous electrolyte in a lithium-ion secondary battery using a positive electrode active material which operates at a high potential. A method for producing a coated positive electrode active material for a lithium-ion secondary battery includes coating a surface of a positive electrode active material with an oxide-based solid electrolyte by a mechanical coating method and then conducting heat treatment at 300° C. or higher, and the positive electrode active material has an average potential of extraction and insertion of lithium of 4.5V or more and 5.0V or less based on Li+/Li.
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公开(公告)号：US20210197278A1
公开(公告)日：2021-07-01
申请号：US17181211
申请日：2021-02-22
Applicant: OSAKA UNIVERSITY
Inventor： Tomokazu SANO , Akio HIROSE , Yuji SANO
Abstract: A metal additive manufacturing technique is provided to improve various characteristics by irradiation of a pulse laser without disposing a transparent medium. A metal additive manufacturing device includes: a material supply source configured to supply a material to be deposited; a heat source configured to melt the material by outputting an energy beam; a moving driver configured to scan at least the energy beam; and a laser irradiator configured to irradiate a solidified portion of the material in a temperature lowering process with a pulse laser.
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