公开(公告)号：US08262641B2

公开(公告)日：2012-09-11

申请号：US12537497

申请日：2009-08-07

Applicant: Lionel Vedrine ,  Paul G. Alchas ,  Christopher N. Cindrich

Inventor： Lionel Vedrine ,  Paul G. Alchas ,  Christopher N. Cindrich

IPC: A61M5/32 ,  A61B19/00

CPC classification number: A61J1/2096 ,  A61J1/1406 ,  A61J1/201 ,  A61J1/2055 ,  A61M5/1782 ,  A61M2039/042

Abstract: A filling system for syringes utilizing short needles to be filled from a vial having a thick septum is described. The system may be useful in any situation where the septum or vial stopper of a medication container is thicker than the usable length of the needle on the delivery device. Preferably, the syringe is filled just prior to use. The short needle includes an optional limiter which only permits a certain predetermined length of the needle cannula to protrude beyond the limiter a distance which limits penetration of the needle tip into both the skin and a vial stopper. The system and adapter may be useful for needles having a protrusion distance from approximately 0.5 mm to 3 mm, or any needle with a protrusion length shorter that the thickness of a septum to be accessed. Furthermore, a device is provided with shielding capabilities to shield the needle of the device.

Abstract translation: 描述了从具有厚的隔膜的小瓶中填充使用短针的注射器的填充系统。 在药物容器的隔膜或药瓶塞子比输送装置上的针的可用长度更厚的任何情况下，该系统可能是有用的。 优选地，注射器在使用之前被填充。 短针包括可选的限制器，其仅允许针套管的某个预定长度突出超过限制器一定距离，该距离限制针尖进入皮肤和药瓶塞子的穿透距离。 系统和适配器对于具有大约0.5mm至3mm的突出距离的针或具有比要访问的隔膜的厚度更短的突出长度的针可能是有用的。 此外，设备具有屏蔽能力以屏蔽设备的针。

公开(公告)号：US08225826B2

公开(公告)日：2012-07-24

申请号：US13111640

申请日：2011-05-19

Applicant: Petri Horppu ,  Anna Ellstrom

Inventor： Petri Horppu ,  Anna Ellstrom

IPC: A61M5/32

CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61J1/2051 ,  A61J1/2089

Abstract: A fluid transfer device for transferring fluid from a first fluid container to a second fluid container such as a piercing member protection device. The fluid transfer device can comprise a longitudinal axis A and a first connection part comprising a connector that connects to the first fluid container. The fluid transfer device can further comprise a second connection part rotatably mounted to the first connection part by a mounting element, and the second connection part can further comprise a threaded coupling that connects the second fluid container. The mounting element can enable turning of the second connection part with respect to the first connection part. Such a device can allow a user to safely turn e.g., a syringe after assembly to read a volume indication or similar.

Abstract translation: 一种流体输送装置，用于将流体从第一流体容器传送到诸如刺穿构件保护装置的第二流体容器。 流体输送装置可以包括纵向轴线A和包括连接到第一流体容器的连接器的第一连接部件。 流体传送装置还可以包括通过安装元件可旋转地安装到第一连接部分的第二连接部分，并且第二连接部分还可包括连接第二流体容器的螺纹连接件。 安装元件能够使第二连接部相对于第一连接部转动。 这样的装置可以允许用户在组装之后安全地转动注射器以读取体积指示或类似物。

公开(公告)号：US20120184938A1

公开(公告)日：2012-07-19

申请号：US13498378

申请日：2010-09-21

Applicant: Nimrod Lev ,  Niv Ben Shalom

Inventor： Nimrod Lev ,  Niv Ben Shalom

IPC: A61J1/20

CPC classification number: B65D51/002 ,  A61J1/1406 ,  A61J1/1425 ,  A61J1/201 ,  A61J1/2051 ,  A61J1/2055 ,  A61J1/2065 ,  A61J1/2096

Abstract: Vial assemblages having a vial and a pre-attached fluid transfer device for use with a needleless syringe for enabling flow communication between the syringe and the vial. The fluid transfer device includes an elongated tubular flow member having a connector for sealing flow communication with the needleless syringe and a spike having a spike end for puncturing the vial for enabling flow communication between the needleless syringe and vial interior. The spike end is in intimate sealing contact with the vial's stopper. The fluid transfer device also includes a manually removable closure for initially sealing the connector and, on removal, exposing the connector.

Abstract translation: 小瓶组合件具有小瓶和预附接的流体输送装置，用于与无针注射器一起使用以实现注射器和小瓶之间的流动连通。 流体输送装置包括细长的管状流动构件，其具有用于密封与无针注射器的流动连通的连接器，以及尖头，具有用于刺穿小瓶的尖端，以实现无针注射器和小瓶内部之间的流动连通。 尖端与小瓶的塞子密封接触。 流体输送装置还包括手动可拆卸的封闭件，用于初始密封连接器，并且在移除时暴露连接器。

公开(公告)号：US20120179129A1

公开(公告)日：2012-07-12

申请号：US13496781

申请日：2010-12-03

Applicant: Masaomi Imai

Inventor： Masaomi Imai

IPC: A61J1/20

CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61J1/2055 ,  A61J1/2068

Abstract: A vial adapter is provided with a fitting portion which can be fitted into the head portion of a vial, and a hollow needle with a side hole. The base end portion of the needle is provided with a stopper contact portion which contacts the top surface of a stopper when the fitting portion is fitted in the head portion of the vial. When the fitting portion is fitted in the head portion of the vial, the stopper contact portion contacts the top surface of the stopper, and the fitting portion is fixed to the head portion of the vial by a claw engaging with the head portion of the vial, and further, the region of the side hole nearest the base end portion of the needle is positioned either roughly at the bottom surface of the stopper or inside of the stopper.

Abstract translation: 小瓶适配器设置有可装配在小瓶的头部中的装配部分和具有侧孔的空心针。 针的基端部设置有止动器接触部，该接合部在嵌合部嵌入小瓶的头部时与接合件的顶面接触。 当装配部分装配在小瓶的头部中时，止动器接触部分接触止动器的顶表面，并且装配部分通过与小瓶的头部接合的爪固定到小瓶的头部 此外，最接近针的基端部的侧孔的区域大致位于止动器的底面或止动件的内部。

公开(公告)号：US08211082B2

公开(公告)日：2012-07-03

申请号：US12305640

申请日：2007-06-19

Applicant: Mitsuru Hasegawa ,  Atsushi Ishikawa ,  Suguru Oyagi ,  Takeshi Ohguro

Inventor： Mitsuru Hasegawa ,  Atsushi Ishikawa ,  Suguru Oyagi ,  Takeshi Ohguro

IPC: A61M5/32

CPC classification number: A61J1/2096 ,  A61J1/10 ,  A61J1/1475 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2017 ,  A61J1/2058 ,  A61J1/2062 ,  A61J1/2072 ,  A61J1/2075 ,  A61J1/2086 ,  A61M5/162 ,  A61M2005/1623 ,  A61M2205/7536

Abstract: To provide a drug solution preparing kit which can be handled with ease in a substantially aseptic manner, and has no risk that a leakage of a drug solution such as a splash and a dispersion of an aerosol to an ambient environment occurs upon preparation of the drug solution There is provided a drug solution preparing kit including a pre-filled syringe and a transfusing tool, wherein the pre-filled syringe includes a sealing member which seals the tip end and can not be removed from the tip end, and that the transfusing tool includes a one-way valve which can discharge only gas from the system in an irreversible manner, and a filter which is provided so as to adjoin to the second communication channel with respect to the one-way valve.

Abstract translation: 提供可以以基本无菌的方式容易地处理的药物溶液制备试剂盒，并且不存在药物制剂在制备药物时发生诸如飞溅物和气溶胶分散体到周围环境的泄漏的风险 溶液提供了一种药液制备试剂盒，其包括预填充注射器和输液工具，其中预填充注射器包括密封前端并且不能从末端移除的密封构件，并且输液器 包括能够以不可逆方式从系统排出气体的单向阀，以及设置成与第二连通路相对于单向阀相邻的过滤器。

公开(公告)号：US08209941B2

公开(公告)日：2012-07-03

申请号：US12610759

申请日：2009-11-02

Applicant: Joel A. Osborne ,  Dennis Tribble ,  Abdul Wahid Khan ,  Morris W. Wallace ,  Edward J. Lefebre

Inventor： Joel A. Osborne ,  Dennis Tribble ,  Abdul Wahid Khan ,  Morris W. Wallace ,  Edward J. Lefebre

IPC: B65B1/04

CPC classification number: B65B3/003 ,  A61J1/201 ,  A61J1/2096

Abstract: An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device. The system includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time.

Abstract translation: 一种用于在药物递送装置中制备规定剂量的药物的自动药物制备系统。 该系统包括多个站，用于接收，处理和处理药物递送装置，使得规定剂量的药物被递送到药物递送装置，以及运送装置，其接收并保持多于一个药物递送装置并移动药物递送装置 设备以受控的方式从一个站到另一个站。 该系统被配置为使得两个或更多个单独的药物递送装置可以同时作用。

公开(公告)号：US20120156278A1

公开(公告)日：2012-06-21

申请号：US13330530

申请日：2011-12-19

Applicant: Roberto Beretta ,  Nicholas A. Grippi

Inventor： Roberto Beretta ,  Nicholas A. Grippi

IPC: A61K9/70 ,  A61P7/04 ,  A61K35/14

CPC classification number: A61B17/00491 ,  A61B2017/00495 ,  A61J1/062 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2041 ,  A61J1/2065 ,  A61J1/2089 ,  A61J1/2093

Abstract: A method of regenerating tissue in a living organism. The method includes the act of contacting an affected area of the living organism with a solid-fibrin web, the solid-fibrin web comprising platelets that release growth factors about one minute after contact to regenerate the tissue in the living organism.

Abstract translation: 一种在生物体内再生组织的方法。 该方法包括使生物体的受影响区域与固体纤维蛋白网接触的作用，所述固体纤维蛋白网包含在接触后约1分钟释放生长因子的血小板以再生生物体中的组织。

公开(公告)号：US08202258B2

公开(公告)日：2012-06-19

申请号：US10571314

申请日：2003-09-11

Applicant: Jean-Pascal Zambaux ,  Jean Rousseau

Inventor： Jean-Pascal Zambaux ,  Jean Rousseau

IPC: A61M5/32

CPC classification number: A61J1/2089 ,  A61J1/201 ,  A61J1/2013 ,  A61L31/126 ,  A61L31/128 ,  A61L31/129 ,  A61M5/329

Abstract: The invention relates to a plastic needle.The plastic needle of the invention is made of a polyarylethercetone polymer.The invention finds industrial applicability in particular in medical and analysis fields.

Abstract translation: 本发明涉及塑料针。 本发明的塑料针由聚芳基醚聚合物制成。 本发明特别适用于医疗和分析领域。

公开(公告)号：US20120123382A1

公开(公告)日：2012-05-17

申请号：US13384172

申请日：2010-07-12

Applicant: Tomohiko Kubo

Inventor： Tomohiko Kubo

IPC: A61J1/20

CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2051 ,  A61J1/2075 ,  A61J1/2082

Abstract: The present invention is a device capable of preventing an operation of establishing communication between a syringe and a vial from being forgotten by error. Holding means constituting a connection device includes: a syringe holding member to be attached to a syringe; a cannula holding member which includes a double-head cannula, is located at a retracted position retracted with respect to the syringe holding member in the pre-use state, and is advanced to an advanced position abutting on the syringe holding member in the use state; and separation preventing means which engages the syringe to prevent separation of the syringe from the syringe holding member in the state where the cannula holding member is located at the retracted position. When the cannula holding member is located at the advanced position, the separation preventing means releases an engagement state with the syringe to permit the separation of the syringe from the syringe holding member.

Abstract translation: 本发明是能够防止注射器与小瓶之间建立通信的操作被遗忘的装置。 构成连接装置的保持装置包括：注射器保持构件，其被附接到注射器; 包括双头插管的套管保持构件位于相对于注射器保持构件在预先使用状态下缩回的缩回位置，并且在使用状态下前进到与注射器保持构件抵接的前进位置 ; 以及分离防止装置，其在所述套管保持构件位于所述缩回位置的状态下接合所述注射器以防止所述注射器与所述注射器保持构件分离。 当套管保持构件位于前进位置时，分离防止装置释放与注射器的接合状态，以允许注射器与注射器保持构件分离。

公开(公告)号：US08177768B2

公开(公告)日：2012-05-15

申请号：US11061290

申请日：2005-02-18

Applicant: Karl R. Leinsing

Inventor： Karl R. Leinsing

IPC: A61M5/32

CPC classification number: A61J1/2089 ,  A61J1/201 ,  A61J1/2044 ,  A61J1/2055 ,  A61J1/2096 ,  A61M39/045 ,  A61M39/10 ,  A61M39/26 ,  B01L3/50825 ,  B01L2200/023 ,  B01L2200/026 ,  B01L2300/049 ,  Y10S206/828 ,  Y10S215/03 ,  Y10S604/905

Abstract: A vial adapter having a needle-free valve, a sharpened cannula used to perforate a vial's rubber stopper, and a circular array of claws of different lengths to engage vial closures of different diameters. The array of claws includes a first set of claws each having a first length extending inwardly from the periphery of the housing of the adapter and a second set of claws alternating with the first set of claws and each having a longer length. The second set of claws are mounted so that they deflect and plastically deform out of the way in the case where the adapter is engaged with a vial that exceeds a predetermined size. The housing includes a shroud that is at least as long as the sharpened cannula to protect medical personnel who use the adapter from inadvertent punctures. The needle-free valve includes a resiliently deformable piston element with a naturally open bore. The interior of the piston provides a fluid flow path through the adapter. In one embodiment, the first set of claws of the adapter may be used with a vial closure of at approximately 20 mm in diameter and the second set of claws may be used with a vial closure of approximately 13 to 17 mm in diameter.

Abstract translation: 具有无针阀的小瓶适配器，用于穿孔小瓶的橡胶塞的尖锐插管和不同长度的圆形圆形阵列以接合不同直径的小瓶盖。 爪阵列包括第一组爪，每组具有从适配器的壳体的周边向内延伸的第一长度和与第一组爪交替的每个爪具有较长长度的第二组爪。 第二组爪被安装成使得它们在适配器与超过预定尺寸的小瓶接合的情况下偏转和塑性变形。 壳体包括至少与尖锐插管一样长的护罩，以保护使用适配器的医务人员无意中穿刺。 无针阀包括具有自然开孔的可弹性变形的活塞元件。 活塞的内部提供通过适配器的流体流动路径。 在一个实施例中，适配器的第一组爪可以与直径为大约20mm的小瓶盖一起使用，并且第二组爪可以与直径约13至17mm的小瓶封闭件一起使用。