公开(公告)号：US08162917B2

公开(公告)日：2012-04-24

申请号：US12406670

申请日：2009-03-18

Applicant: Matthew J. Stepovich ,  Michael I. Falkel

Inventor： Matthew J. Stepovich ,  Michael I. Falkel

IPC: A61B19/00

CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2072

Abstract: A device for delivering buffer solution into a buffer cartridge comprises a needle assembly and a pusher. The septa of a buffer cartridge and an anesthetic cartridge are advanced onto a transfer needle, and the pusher advances a plunger into the buffer cartridge to deliver buffer through the transfer needle into the anesthetic cartridge. A separate exhaust needle allows excess anesthetic from the anesthetic cartridge to be exhausted. A compression member is usually provided to maintain a force against the plunger on the buffer cartridge to pressurize and stabilize the contents during sterilization and/or storage.

Abstract translation: 用于将缓冲溶液输送到缓冲筒中的装置包括针组件和推动器。 缓冲药筒和麻醉药筒的隔垫前进到转移针上，推动器将柱塞推进到缓冲药筒中，以通过转移针将缓冲液输送到麻醉药筒中。 单独的排气针允许麻醉药筒的过量麻醉剂被耗尽。 通常设置压缩构件以在消毒和/或存储期间保持抵抗缓冲筒上的柱塞的力以对内容物进行加压和稳定。

公开(公告)号：US20120053555A1

公开(公告)日：2012-03-01

申请号：US13217967

申请日：2011-08-25

Applicant: Scott Ariagno ,  Frederick Charles Houghton, II ,  Daniel E. Roush

Inventor： Scott Ariagno ,  Frederick Charles Houghton, II ,  Daniel E. Roush

IPC: A61J1/14

CPC classification number: A61J1/2089 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2065 ,  A61J1/2075 ,  A61J1/2082 ,  A61J1/2086

Abstract: A reconstitution assembly includes a housing including a lower sleeve and an upper sleeve, including a first container and a second container disposed vertically opposite the first container. A transfer set assembly is disposed within the housing between the first container and the second container. The transfer set assembly includes an upper spike housing and a lower spike housing, with a flow path defined through the upper spike housing and the lower spike housing. The transfer set assembly is configured to access contents of the first container and then upon the activation of a triggering mechanism, create a fluid pathway between the first container and the second container. The triggering mechanism includes trigger fingers which ensure the transfer set assembly sequentially accesses the contents of the first container before accessing the contents of the second container. The disposition of the first container activates the triggering mechanism.

Abstract translation: 重构组件包括壳体，该壳体包括下套筒和上套筒，包括第一容器和与第一容器垂直相对设置的第二容器。 转移组件设置在第一容器和第二容器之间的壳体内。 传送组件包括上部尖钉壳体和下部突出壳体，其中流动路径限定穿过上部突出壳体和下部突出壳体。 传送组件被配置为访问第一容器的内容物，然后在激活触发机构时，在第一容器和第二容器之间产生流体通路。 触发机构包括触发指，其确保在访问第二容器的内容物之前传送组件顺序地访问第一容器的内容物。 第一容器的配置激活触发机制。

公开(公告)号：US20120029464A1

公开(公告)日：2012-02-02

申请号：US13123685

申请日：2009-10-15

Applicant: Lasse Kragelund ,  John Thrane Hansen

Inventor： Lasse Kragelund ,  John Thrane Hansen

IPC: A61J1/14

CPC classification number: A61J1/2089 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2037 ,  A61J1/2062 ,  A61J1/2075 ,  A61J1/2096 ,  A61M5/162 ,  A61M2039/0027

Abstract: A mixing system (1) adapted to allow first contents of a first container (2) and second contents of a second container (3) to mix to form a material. The mixed material is retrieved to a syringe (20) without being foamed. The mixing system (1) comprises a transfer unit (5) which is adapted to receive the first container (2) at a first port (11), the second container (3) at a second port (12) and the syringe (20) at a third port (13). The transfer unit (5) further houses a number of fluid pathways (14, 15, 16) interconnecting the three ports (11, 12, 13) as well as a number of flow control members (17, 18, 19, 22) for controlling fluid flow between the containers (2, 3) and the syringe (20). At least one of the flow control members (17, 18, 19, 22) allows a user to switch between two states of fluid flow, one in which fluid flow is enabled between the first port (11) and the third port (13) as well as between the third port (13) and the second port (12), and one in which fluid flow is enabled between the second port (12) and the third port (13). The invention also relates to a transfer unit comprising first and second ports for receiving first and second containers, respectively, a third port for coupling to a syringe, a number of fluid pathways interconnecting the ports, at least one flow control member which allows a user to switch between two states of fluid flow, and a locking means to ensure that the at least one flow control member can only be manipulated when a syringe is coupled to the third port.

Abstract translation: 一种适于允许第一容器（2）的第一内容物和第二容器（3）的第二内容物混合以形成材料的混合系统（1）。 将混合的材料回收到注射器（20）而不发泡。 混合系统（1）包括转移单元（5），其适于在第一端口（11）处容纳第一容器（2），第二容器（3）在第二端口（12）和注射器（20） ）在第三端口（13）。 传送单元（5）还容纳多个互连三个端口（11,12,13）的流体路径（14,15,16）以及多个流量控制构件（17,18,19,22），用于 控制容器（2,3）和注射器（20）之间的流体流动。 至少一个流量控制构件（17,18,19,22）允许使用者在两个流体流动状态之间切换，其中流体流在第一端口（11）和第三端口（13）之间启用， 以及在第三端口（13）和第二端口（12）之间以及在第二端口（12）和第三端口（13）之间能够进行流体流动的端口。 本发明还涉及一种转移单元，其包括用于分别接收第一和第二容器的第一和第二端口，用于连接到注射器的第三端口，将端口互连的多个流体通路，允许使用者的至少一个流量控制构件 以在两种流体流动状态之间切换，以及锁定装置，以确保只有当注射器联接到第三端口时，才能操纵至少一个流量控制构件。

公开(公告)号：US20120012631A1

公开(公告)日：2012-01-19

申请号：US13200207

申请日：2011-09-21

Applicant: Gale H. Thorne, JR. ,  Kendall Patterick Thorne

Inventor： Gale H. Thorne, JR. ,  Kendall Patterick Thorne

IPC: B26F3/02

CPC classification number: A61J1/16 ,  A61J1/201 ,  A61M5/162 ,  A61M39/162 ,  A61M39/18 ,  A61M2202/049 ,  Y10T225/10

Abstract: A method for remotely applying a force to a tether affixed to a sterilizing swab package to open the package for use of a swab disposed therein. The method may be applied to sterilizing a septum of a vial disposed within a bag.

Abstract translation: 用于远程地施加力的系统的方法，所述系固定到消毒拭子包装以打开用于使用其中布置的拭子的包装。 该方法可以应用于对设置在袋内的小瓶的隔膜进行消毒。

公开(公告)号：US08088118B2

公开(公告)日：2012-01-03

申请号：US12157867

申请日：2008-06-13

Applicant: David L. Reynolds ,  Daniel MacDonald ,  Julie Trepanier ,  Steven Raymond ,  Caroline Lavoie

Inventor： David L. Reynolds ,  Daniel MacDonald ,  Julie Trepanier ,  Steven Raymond ,  Caroline Lavoie

IPC: A61B19/00 ,  A61M37/00

CPC classification number: A61J1/2089 ,  A61J1/062 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2051

Abstract: A system and method for transferring a fluid from a first container to a second container, the system comprising a first container (112) having a fluid (126) therein, the first container being sealed by a septum (124) and a piston (122), the second container being sealed at its mouth by a pierceable septum (132) and having a plunger (130) at the opposite end, a moveable needle shuttle (116) having first (144) and second (146) piercing ends, the arrangement being such that upon advancement of the first container with respect to the second container, a second one of the piercing ends (144) is adapted to pierce plunger (130) of the second container and a first piercing end (146) being designed to pierce the septum (124) of the first container.

Abstract translation: 一种用于将流体从第一容器传送到第二容器的系统和方法，所述系统包括其中具有流体（126）的第一容器（112），所述第一容器由隔膜（124）和活塞（122）密封 ），第二容器在其口部由可刺破的隔膜（132）密封并且在相对端具有柱塞（130），具有第一（144）和第二（146）穿刺端部的可移动的针梭（116） 布置使得在相对于第二容器推进第一容器时，穿刺端（144）中的第二个适于刺穿第二容器的柱塞（130），并且第一刺穿端（146）设计成 刺穿第一个容器的隔膜（124）。

公开(公告)号：US08079977B2

公开(公告)日：2011-12-20

申请号：US12526823

申请日：2008-02-02

Applicant: Yuying Ding

Inventor： Yuying Ding

IPC: A61M37/00

CPC classification number: A61J1/2096 ,  A61J1/062 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/202 ,  A61M5/1782 ,  A61M5/284 ,  A61M2005/3139

Abstract: A device for automatically mixing powder for injection, includes an injector body, a solvent bottle, a needle, a first impelling unit and a second impelling unit. The injector body has a solute bottle and its mouth is opposite the mouth of the solvent bottle. The first impelling unit is disposed upon the solvent bottle. The second impelling unit is sleeved with a needle and located between the mouth of solute bottle and mouth of solvent bottle. A first and a second impelling sleeve-are driven by the solvent bottle to slide along the solute bottle, so the first end of the needle is fixed and extend through the solute bottle. The solvent bottle drives the first impelling sleeve and second impelling sleeve to turn with each other. The second impelling sleeve slides opposite the first impelling sleeve to make the second end of the needle extend through the solvent bottle.

Abstract translation: 用于自动混合用于注射的粉末的装置包括喷射器主体，溶剂瓶，针，第一推动单元和第二推进单元。 注射器主体具有溶质瓶，其口与溶剂瓶的口相对。 第一推进单元设置在溶剂瓶上。 第二个推动单元用针套住，位于溶质瓶口和溶剂瓶口之间。 第一和第二推力套筒由溶剂瓶驱动，沿着溶质瓶滑动，因此针头的第一端固定并延伸穿过溶质瓶。 溶剂瓶驱动第一推力套筒和第二推力套筒彼此转动。 第二推动套筒与第一推力套筒相对滑动，使得针的第二端延伸穿过溶剂瓶。

公开(公告)号：US08070739B2

公开(公告)日：2011-12-06

申请号：US12063176

申请日：2006-08-08

Applicant: Freddy Zinger ,  Igor Denenburg ,  Moshe Gilboa

Inventor： Freddy Zinger ,  Igor Denenburg ,  Moshe Gilboa

IPC: A61B19/00 ,  A61M5/32

CPC classification number: A61J1/2089 ,  A61J1/201 ,  A61J1/2055 ,  A61J1/2065 ,  A61J1/2096

Abstract: Liquid drug transfer devices including a vial adapter designed for failsafe correct snap fitting on a medicinal vial for ensuring flow communication with the vial's interior. The vial adapters include at least two non-adjacent vial retention flex members for snap fitting over a vial opening for vial retention purposes and at least two non-adjacent vial guidance flex members longer than their counterpart vial retention flex members for guiding a vial adapter with respect to a vial prior to snap fitting the vial adapter thereon.

Abstract translation: 液体药物转移装置，包括设计用于故障保护的小瓶适配器，正确地配合在药瓶上，以确保与小瓶内部的流动连通。 小瓶适配器包括至少两个不相邻的小瓶保持柔性构件，用于卡扣配合在小瓶开口上用于小瓶保持目的，并且至少两个不相邻的小瓶引导柔性构件比其对应的小瓶保持柔性构件更长，用于将小瓶适配器引导至 在将小瓶适配器卡在其上之前，相对于小瓶。

公开(公告)号：US20110291406A1

公开(公告)日：2011-12-01

申请号：US12958501

申请日：2010-12-02

Applicant: Torsten Kraft ,  James Richard McLaren ,  Allen John Pearson

Inventor： Torsten Kraft ,  James Richard McLaren ,  Allen John Pearson

IPC: F16L27/10

CPC classification number: A61J1/2089 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2055

Abstract: The present application concerns a connecting element for establishing a frictional connection with a neck portion of liquid drug container, like a vial. The connecting element may include a basic structure and contact elements connected with the basic structure that provide contact surfaces for contacting the neck portion. The contact surfaces may be configured to form a receiving space for receiving the neck portion. The receiving space can be enlarged by moving apart the contact surfaces.

Abstract translation: 本申请涉及用于建立与液体药物容器的颈部的摩擦连接的连接元件，如小瓶。 连接元件可以包括基本结构和与基本结构连接的接触元件，其提供用于接触颈部的接触表面。 接触表面可以被构造成形成用于接纳颈部的容纳空间。 可以通过移开接触面来扩大接收空间。

公开(公告)号：US08062280B2

公开(公告)日：2011-11-22

申请号：US12194137

申请日：2008-08-19

Applicant: Steven C. Jepson ,  James B. Winje ,  Mark C. Perry ,  David D. Hsu ,  Dan Liu ,  Richard F. Chamernik ,  Eric J. Henaut ,  Gianni Di Stefani ,  Georges Rondeau ,  Lewis E. Daniels, Jr.

Inventor： Steven C. Jepson ,  James B. Winje ,  Mark C. Perry ,  David D. Hsu ,  Dan Liu ,  Richard F. Chamernik ,  Eric J. Henaut ,  Gianni Di Stefani ,  Georges Rondeau ,  Lewis E. Daniels, Jr.

IPC: A61B19/00

CPC classification number: A61M39/26 ,  A61J1/10 ,  A61J1/1475 ,  A61J1/201 ,  A61J1/2044 ,  A61J1/2051 ,  A61M5/162 ,  A61M39/1011 ,  A61M2039/1072 ,  A61M2039/263 ,  A61M2039/267

Abstract: A port assembly includes a housing with an opening and a bore therethrough, a slit septum disposed in the bore to control access through the opening, a base joined to the housing and having a membrane attached thereto, a perforator having a first end abutting the slit septum and a second end aligned with the membrane, and a resilient member disposed between the perforator and the base. The port assembly may be used in a fluid container that includes a receptacle for retaining a fluid, and at least one conduit in communication with the receptacle. The at least one conduit may be defined, at least in part, by the port assembly.

Abstract translation: 端口组件包括具有开口和穿过其中的孔的壳体，设置在所述孔中的狭缝隔膜以控制通过所述开口的通路，连接到所述壳体并具有附接到其上的膜的基部;穿孔器，其具有邻接所述狭缝的第一端 隔膜和与膜对准的第二端，以及设置在穿孔器和基部之间的弹性构件。 端口组件可以用在包括用于保持流体的容器和与插座连通的至少一个导管的流体容器中。 至少一个管道可以至少部分地由端口组件限定。

公开(公告)号：US20110257621A1

公开(公告)日：2011-10-20

申请号：US13175605

申请日：2011-07-01

Applicant: Thomas F. Fangrow

Inventor： Thomas F. Fangrow

IPC: A61J1/22 ,  B23P11/00

CPC classification number: A61J1/22 ,  A61J1/1406 ,  A61J1/1412 ,  A61J1/201 ,  A61J1/2048 ,  A61J1/2055 ,  A61J1/2065 ,  A61J1/2072 ,  A61J1/2075 ,  A61J1/2079 ,  A61J1/2082 ,  A61J1/2086 ,  A61J1/2089 ,  A61J1/2096 ,  A61J2200/10 ,  A61J2200/76 ,  Y10T29/49826 ,  Y10T29/49885 ,  Y10T137/0402

Abstract: In certain embodiments, a vial adaptor for removing liquid contents from a vial includes a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial includes a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.

Abstract translation: 在某些实施例中，用于从小瓶中去除液体内容物的小瓶适配器包括刺穿构件和袋。 袋子可以被包含在刺穿构件内，使得当小瓶适配器与小瓶联接时将袋子引入到小瓶中。 在一些实施例中，当液体通过适配器从小瓶中移出时，袋子在小瓶内膨胀，从而调节小瓶内的压力。 在其他实施例中，小瓶包括用于在液体从其中移除时调节小瓶内的压力的袋。 在一些实施例中，将小瓶适配器与小瓶联接以便去除液体。 在一些实施例中，当液体经由适配器从小瓶中移出时，袋在小瓶内膨胀，并且在其他实施例中，袋在小瓶内收缩。