METHOD FOR PRODUCING A FUSION MIXTURE FOR TRANSFER OF A CHARGED MOLECULE INTO AND/OR THROUGH A LIPID MEMBRANE
    188.
    发明申请
    METHOD FOR PRODUCING A FUSION MIXTURE FOR TRANSFER OF A CHARGED MOLECULE INTO AND/OR THROUGH A LIPID MEMBRANE 审中-公开
    用于生产用于将充电分子转移到和/或通过脂肪膜的熔融混合物的方法

    公开(公告)号:US20170009255A1

    公开(公告)日:2017-01-12

    申请号:US15205967

    申请日:2016-07-08

    CPC classification number: C12N15/88 A61K9/1272 A61K9/1278 A61K38/00 B01J13/10

    Abstract: A method for producing a fusion mixture for a transfer of a charged molecule into and/or through a lipid membrane is disclosed. In an embodiment, the method comprises: providing an initial mixture comprising a positively charged amphipathic molecule A, an aromatic molecule B with hydrophobic range and a neutral, amphipathic molecule C, whereby the molecule types are at hand in a ratio A:B:C of 1-2:0.02-1:0-1 mol/mol; generating a fusogenic liposome by absorption of the initial mixture in a watery solvent; providing a charged molecule; forming a complex from the charged molecule and a neutralizing agent; and incubating the complex with the fusogenic liposome so that a fusion mixture is obtained.

    Abstract translation: 公开了一种用于产生用于将带电分子转移到脂质膜中和/或通过脂质膜转移的融合混合物的方法。 在一个实施方案中,该方法包括:提供包含带正电荷的两亲性分子A,具有疏水范围的芳族分子B和中性两亲分子C的初始混合物,由此分子类型在手中的比例为A:B:C 为1-2:0.02-1:0-1mol / mol; 通过在水溶剂中吸收初始混合物产生融合脂质体; 提供带电分子; 从带电分子和中和剂形成络合物; 并将该复合物与融合脂质体孵育以获得融合混合物。

    RENEWABLE SELF-HEALING CAPSULE SYSTEM
    189.
    发明申请
    RENEWABLE SELF-HEALING CAPSULE SYSTEM 审中-公开
    可再生自愈型胶囊系统

    公开(公告)号:US20160230006A1

    公开(公告)日:2016-08-11

    申请号:US15098446

    申请日:2016-04-14

    CPC classification number: C08L89/00 B01J13/08 B01J13/10 B01J13/14 C11C3/00

    Abstract: A renewable material for releasing a self-healing agent includes a renewable polymeric substrate with capsules and a reactant dispersed in the renewable polymeric substrate. The capsules may be formed from a first renewable shell polymer and may enclose the renewable self-healing agent. The reactant may be suitable for reacting with the renewable self-healing agent to form a polymer.

    Abstract translation: 用于释放自愈剂的可再生材料包括具有胶囊的可再生聚合物基材和分散在可再生聚合物基材中的反应物。 胶囊可以由第一可再生壳聚合物形成并且可以包围可再生自愈剂。 反应物可以适于与可再生自愈剂反应以形成聚合物。

    Renewable self-healing capsule system
    190.
    发明授权
    Renewable self-healing capsule system 有权
    可再生自愈胶囊系统

    公开(公告)号:US09404065B2

    公开(公告)日:2016-08-02

    申请号:US13732738

    申请日:2013-01-02

    CPC classification number: C08L89/00 B01J13/08 B01J13/10 B01J13/14 C11C3/00

    Abstract: A renewable material for releasing a self-healing agent includes a renewable polymeric substrate with capsules and a reactant dispersed in the renewable polymeric substrate. The capsules may be formed from a first renewable shell polymer and may enclose the renewable self-healing agent. The reactant may be suitable for reacting with the renewable self-healing agent to form a polymer.

    Abstract translation: 用于释放自愈剂的可再生材料包括具有胶囊的可再生聚合物基材和分散在可再生聚合物基材中的反应物。 胶囊可以由第一可再生壳聚合物形成并且可以包围可再生自愈剂。 反应物可以适于与可再生自愈剂反应以形成聚合物。

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